RU2012123787A - METHOD FOR PRODUCING A WATER-SOLUBLE BACTERICIDAL DRUG - Google Patents
METHOD FOR PRODUCING A WATER-SOLUBLE BACTERICIDAL DRUG Download PDFInfo
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- RU2012123787A RU2012123787A RU2012123787/10A RU2012123787A RU2012123787A RU 2012123787 A RU2012123787 A RU 2012123787A RU 2012123787/10 A RU2012123787/10 A RU 2012123787/10A RU 2012123787 A RU2012123787 A RU 2012123787A RU 2012123787 A RU2012123787 A RU 2012123787A
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- silver
- water
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1. Способ получения водорастворимого бактерицидного препарата, включающий смешение исходных компонентов, с последующей стабилизацией металлического серебра полимером путем восстановления ионного серебра в водных растворах с последующей сушкой, отличающийся тем, что восстановление ионного серебра в водном растворе ведут при взаимодействии нитрата серебра, лизоцима и желатина, при следующем соотношении компонентов, мас.%: лизоцим 0,043-0,045, нитрат серебра (AgNO) 0,073-0,085, желатин 0,071-0,080, вода HO остальное, полученную смесь обрабатывают УФ-облучением, затем подвергают диализу и сушке, при этом сушку проводят под вакуумом.2. Способ по п.1, отличающийся тем, что полученную смесь исходных компонентов подвергают УФ-облучению при непрерывном перемешивании в течение 25-30 минут в диапазоне коротковолнового излучения, 25-30 минут в диапазоне длинноволнового излучения, а затем 55-60 минут в диапазоне коротковолнового излучения, а диализ обработанной смеси проводят в течение 24-30 часов при непрерывном перемешивании.1. A method of obtaining a water-soluble bactericidal preparation, including mixing the initial components, followed by stabilization of metallic silver with a polymer by reducing ionic silver in aqueous solutions followed by drying, characterized in that the reduction of ionic silver in an aqueous solution is carried out by the interaction of silver nitrate, lysozyme and gelatin, with the following ratio of components, wt%: lysozyme 0.043-0.045, silver nitrate (AgNO) 0.073-0.085, gelatin 0.071-0.080, water HO, the rest, the resulting mixture is treated with UV irradiation, then dialyzed and dried, while drying is carried out under vacuum 2. The method according to claim 1, characterized in that the resulting mixture of starting components is subjected to UV irradiation with continuous stirring for 25-30 minutes in the short-wavelength range, 25-30 minutes in the long-wavelength range, and then 55-60 minutes in the short-wavelength range. radiation, and the dialysis of the treated mixture is carried out for 24-30 hours with continuous stirring.
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2012123787/10A RU2502259C1 (en) | 2012-06-07 | 2012-06-07 | Method of obtaining water-soluble bactericidal preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2012123787/10A RU2502259C1 (en) | 2012-06-07 | 2012-06-07 | Method of obtaining water-soluble bactericidal preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2012123787A true RU2012123787A (en) | 2013-12-20 |
| RU2502259C1 RU2502259C1 (en) | 2013-12-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012123787/10A RU2502259C1 (en) | 2012-06-07 | 2012-06-07 | Method of obtaining water-soluble bactericidal preparation |
Country Status (1)
| Country | Link |
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| RU (1) | RU2502259C1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111937903A (en) * | 2020-08-25 | 2020-11-17 | 清华大学 | A kind of enzyme protein-nano-silver antibacterial complex and its preparation method and application |
| CN117204439A (en) * | 2023-08-18 | 2023-12-12 | 深圳市前海四零生物技术有限公司 | A new enzyme-silver antiviral and antibacterial compound preparation and its preparation method |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2088234C1 (en) * | 1994-11-25 | 1997-08-27 | Институт высокомолекулярных соединений РАН | Water-soluble bactericidal composition and a method of its preparing |
| RU2140293C1 (en) * | 1999-04-06 | 1999-10-27 | Общество с ограниченной ответственностью "Научно-производственная фирма "ФАИНА" | Bactericide agent |
| CN1538813A (en) * | 2001-07-13 | 2004-10-20 | Composition having bacteriostatic and bactericidal activity against bacterial spores and vegetative cells and method for treating food | |
| RU2333773C1 (en) * | 2007-06-29 | 2008-09-20 | Автономная некоммерческая организация "Институт нанотехнологий Международного фонда конверсии" | Biocide solution and method for obtaining same |
| RU2407289C1 (en) * | 2009-05-13 | 2010-12-27 | Закрытое акционерное общество "Институт прикладной нанотехнологии" | Nanostructured biocide composition |
-
2012
- 2012-06-07 RU RU2012123787/10A patent/RU2502259C1/en active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111937903A (en) * | 2020-08-25 | 2020-11-17 | 清华大学 | A kind of enzyme protein-nano-silver antibacterial complex and its preparation method and application |
| CN117204439A (en) * | 2023-08-18 | 2023-12-12 | 深圳市前海四零生物技术有限公司 | A new enzyme-silver antiviral and antibacterial compound preparation and its preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2502259C1 (en) | 2013-12-27 |
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