RU2009133338A - Композиции, содержащие экстракты cynara scolymus и phaseolus vulgaris, которые полезны для лечения ожирения - Google Patents
Композиции, содержащие экстракты cynara scolymus и phaseolus vulgaris, которые полезны для лечения ожирения Download PDFInfo
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- RU2009133338A RU2009133338A RU2009133338/15A RU2009133338A RU2009133338A RU 2009133338 A RU2009133338 A RU 2009133338A RU 2009133338/15 A RU2009133338/15 A RU 2009133338/15A RU 2009133338 A RU2009133338 A RU 2009133338A RU 2009133338 A RU2009133338 A RU 2009133338A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
1. Композиция, содержащая экстракт Cynara scolymus и экстракт Phaseolus vulgaris с соотношением от 1:0,25 до 1:1. ! 2. Композиция по п.1, в которой экстракт Cynara scolymus имеет содержание кофеоилхинных кислотт в диапазоне от 30 до 60% и содержание гликозидов лютеолина в диапазоне от 2 до 5%. ! 3. Композиция по п.1, в которой экстракт Phaseolus vulgaris отличается содержанием ингибитора альфа-амилазы от 1200 до 1600 ед. USP/мг (ВЭЖХ-титр от 7 до 14% мас./мас.) и содержанием фитогемагглютинина в диапазоне от 12000 до 30000 гемагглютинирующих ед./г. !4. Композиция по п.2, в которой экстракт Phaseolus vulgaris отличается содержанием ингибитора альфа-амилазы от 1200 до 1600 ед. USP/мг (ВЭЖХ-титр от 7 до 14% мас./мас.) и содержанием фитогемагглютинина в диапазоне от 12000 до 30000 гемагглютинирующих ед./г. ! 5. Композиция по любому из пп.1-4, дополнительно содержащая масло Oenothera biennis. ! 6. Применение композиции, определенной в любом из пп.1-5, для получения лекарственных средств с гипогликемическим действием и активностью против ожирения.
Claims (6)
1. Композиция, содержащая экстракт Cynara scolymus и экстракт Phaseolus vulgaris с соотношением от 1:0,25 до 1:1.
2. Композиция по п.1, в которой экстракт Cynara scolymus имеет содержание кофеоилхинных кислотт в диапазоне от 30 до 60% и содержание гликозидов лютеолина в диапазоне от 2 до 5%.
3. Композиция по п.1, в которой экстракт Phaseolus vulgaris отличается содержанием ингибитора альфа-амилазы от 1200 до 1600 ед. USP/мг (ВЭЖХ-титр от 7 до 14% мас./мас.) и содержанием фитогемагглютинина в диапазоне от 12000 до 30000 гемагглютинирующих ед./г.
4. Композиция по п.2, в которой экстракт Phaseolus vulgaris отличается содержанием ингибитора альфа-амилазы от 1200 до 1600 ед. USP/мг (ВЭЖХ-титр от 7 до 14% мас./мас.) и содержанием фитогемагглютинина в диапазоне от 12000 до 30000 гемагглютинирующих ед./г.
5. Композиция по любому из пп.1-4, дополнительно содержащая масло Oenothera biennis.
6. Применение композиции, определенной в любом из пп.1-5, для получения лекарственных средств с гипогликемическим действием и активностью против ожирения.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90532007P | 2007-03-07 | 2007-03-07 | |
| EP07425132.3 | 2007-03-07 | ||
| EP07425132A EP1967198B1 (en) | 2007-03-07 | 2007-03-07 | Formulations containing cynara scolymus and phaseolus vulgaris extracts which are useful in the treatment of obesity |
| US60/905,320 | 2007-03-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2009133338A true RU2009133338A (ru) | 2011-03-10 |
| RU2453323C2 RU2453323C2 (ru) | 2012-06-20 |
Family
ID=38229761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009133338/15A RU2453323C2 (ru) | 2007-03-07 | 2008-03-06 | Композиции, содержащие экстракты cynara scolymus и phaseolus vulgaris, которые полезны для лечения ожирения |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7887854B2 (ru) |
| EP (1) | EP1967198B1 (ru) |
| JP (1) | JP5355424B2 (ru) |
| KR (1) | KR101456555B1 (ru) |
| CN (1) | CN101641111B (ru) |
| AT (1) | ATE431155T1 (ru) |
| AU (1) | AU2008224057B2 (ru) |
| BR (1) | BRPI0808563B1 (ru) |
| CA (1) | CA2680078C (ru) |
| DE (1) | DE602007001128D1 (ru) |
| DK (1) | DK1967198T3 (ru) |
| ES (1) | ES2323815T3 (ru) |
| IL (1) | IL200709A (ru) |
| NO (1) | NO339322B1 (ru) |
| PL (1) | PL1967198T3 (ru) |
| PT (1) | PT1967198E (ru) |
| RU (1) | RU2453323C2 (ru) |
| SI (1) | SI1967198T1 (ru) |
| WO (1) | WO2008107184A1 (ru) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20052450A1 (it) | 2005-12-22 | 2007-06-23 | Indena Spa | Estratti di phaseolus vulgaris loro uso e formulazioni che li contengono |
| CN105816498A (zh) | 2009-04-27 | 2016-08-03 | 玫琳凯有限公司 | 植物性抗痤疮制剂 |
| EP2345646A1 (en) * | 2010-01-14 | 2011-07-20 | InterMed Discovery GmbH | Use of tricyclic sesquiterpene lactones in the treatment of obesity and related diseases and non-therapeutic treatable conditions |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| KR101330190B1 (ko) | 2011-09-20 | 2013-11-15 | (주)그린솔루션스 | 하고초 추출물의 헴 옥시게나아제-1 발현 조절을 통한 지방 생성 억제용 화장료 조성물 |
| DE202012013018U1 (de) | 2011-12-19 | 2014-08-20 | Mary Kay Inc. | Kombination von Pflanzenextrakten zur Verbesserung des Hauttons |
| ITMI20121570A1 (it) * | 2012-09-20 | 2014-03-21 | Indena Spa | Nuovi estratti di cynara scolimus, coffea spp. e olea europaea per il trattamento della sindrome metabolica |
| ITMI20121727A1 (it) * | 2012-10-12 | 2014-04-13 | Indena Spa | Formulazioni per il trattamento e la prevenzione dell'obesita' |
| ITMI20121749A1 (it) * | 2012-10-16 | 2014-04-17 | Indena Spa | Estratti di helianthus annuus utili nel trattamento della sindrome metabolica e nella diminuzione dell'indice glicemico di alimenti e procedimento per la loro preparazione e composizioni che li contengono |
| KR102323049B1 (ko) | 2014-03-10 | 2021-11-05 | 마리 케이 인코포레이티드 | 피부 라이트닝 조성물 |
| DE202014005450U1 (de) * | 2014-07-04 | 2015-10-06 | Ursapharm Arzneimittel Gmbh | Lactosefreies Arzneimittel |
| US20160302451A1 (en) * | 2015-04-16 | 2016-10-20 | Michael Hudnall | Medical Food for Patients with Chronic Liver Disease |
| FR3075570B1 (fr) * | 2017-12-22 | 2020-01-03 | Agro Innovation International | Stimulation de la nitrification d'un sol avec des compositions comprenant un extrait de plante |
| IT201900000367A1 (it) * | 2019-01-10 | 2020-07-10 | Altergon Sa | Composizioni comprendenti un peptide in grado di stimolare la via del segnale gprc6a-dipendente |
| CN110433280A (zh) * | 2019-09-11 | 2019-11-12 | 周口师范学院 | 植物血凝素在制备预防或治疗肥胖药物中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8524275D0 (en) * | 1985-10-02 | 1985-11-06 | Efamol Ltd | Pharmaceutical & dietary compositions |
| DE19627376A1 (de) * | 1996-07-06 | 1998-01-08 | Aar Pharma Adler Apotheke | Verwendung von Artischocken-(Cynara)-Extrakten |
| HRP990080B1 (en) * | 1999-03-12 | 2003-04-30 | Vladimir Leko | Plant mixture and a medical preparation for the treatment of diabetes mellitus, type ii, obtained therefrom |
| US6818234B1 (en) * | 1999-08-27 | 2004-11-16 | Access Business Group International Llc | Dietary food supplement containing natural cyclooxygenase inhibitors and methods for inhibiting pain and inflammation |
| ITMI20051347A1 (it) | 2005-07-14 | 2007-01-15 | Indena Spa | Estratti di cynara scolimus loro uso e formulazioni che li contengono |
| ITMI20052450A1 (it) | 2005-12-22 | 2007-06-23 | Indena Spa | Estratti di phaseolus vulgaris loro uso e formulazioni che li contengono |
-
2007
- 2007-03-07 DE DE602007001128T patent/DE602007001128D1/de active Active
- 2007-03-07 PT PT07425132T patent/PT1967198E/pt unknown
- 2007-03-07 DK DK07425132T patent/DK1967198T3/da active
- 2007-03-07 EP EP07425132A patent/EP1967198B1/en active Active
- 2007-03-07 SI SI200730037T patent/SI1967198T1/sl unknown
- 2007-03-07 ES ES07425132T patent/ES2323815T3/es active Active
- 2007-03-07 PL PL07425132T patent/PL1967198T3/pl unknown
- 2007-03-07 AT AT07425132T patent/ATE431155T1/de active
-
2008
- 2008-03-05 US US12/042,354 patent/US7887854B2/en active Active
- 2008-03-06 WO PCT/EP2008/001787 patent/WO2008107184A1/en not_active Ceased
- 2008-03-06 JP JP2009552122A patent/JP5355424B2/ja not_active Expired - Fee Related
- 2008-03-06 BR BRPI0808563-3A patent/BRPI0808563B1/pt not_active IP Right Cessation
- 2008-03-06 CA CA2680078A patent/CA2680078C/en active Active
- 2008-03-06 US US12/529,990 patent/US7887855B2/en active Active
- 2008-03-06 AU AU2008224057A patent/AU2008224057B2/en not_active Ceased
- 2008-03-06 RU RU2009133338/15A patent/RU2453323C2/ru active
- 2008-03-06 CN CN200880007206XA patent/CN101641111B/zh not_active Expired - Fee Related
- 2008-03-06 KR KR1020097018545A patent/KR101456555B1/ko not_active Expired - Fee Related
-
2009
- 2009-09-03 IL IL200709A patent/IL200709A/en active IP Right Grant
-
2010
- 2010-04-14 NO NO20100527A patent/NO339322B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008224057A1 (en) | 2008-09-12 |
| AU2008224057B2 (en) | 2012-07-19 |
| IL200709A0 (en) | 2010-05-17 |
| PT1967198E (pt) | 2009-06-15 |
| KR20090118051A (ko) | 2009-11-17 |
| IL200709A (en) | 2013-07-31 |
| US20100136145A1 (en) | 2010-06-03 |
| BRPI0808563B1 (pt) | 2018-02-14 |
| NO339322B1 (no) | 2016-11-28 |
| CN101641111A (zh) | 2010-02-03 |
| US20080220097A1 (en) | 2008-09-11 |
| JP2010520246A (ja) | 2010-06-10 |
| RU2453323C2 (ru) | 2012-06-20 |
| EP1967198B1 (en) | 2009-05-13 |
| BRPI0808563A2 (pt) | 2014-09-02 |
| JP5355424B2 (ja) | 2013-11-27 |
| ATE431155T1 (de) | 2009-05-15 |
| US7887854B2 (en) | 2011-02-15 |
| CA2680078A1 (en) | 2008-09-12 |
| EP1967198A1 (en) | 2008-09-10 |
| KR101456555B1 (ko) | 2014-10-31 |
| ES2323815T3 (es) | 2009-07-24 |
| DE602007001128D1 (de) | 2009-06-25 |
| WO2008107184A1 (en) | 2008-09-12 |
| SI1967198T1 (sl) | 2009-08-31 |
| US7887855B2 (en) | 2011-02-15 |
| NO20100527A1 (no) | 2010-05-19 |
| HK1121694A1 (en) | 2009-04-30 |
| CA2680078C (en) | 2016-12-06 |
| PL1967198T3 (pl) | 2009-10-30 |
| CN101641111B (zh) | 2012-05-23 |
| DK1967198T3 (da) | 2009-08-10 |
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