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RU2006127134A - METHOD FOR TREATING DISEASES - Google Patents

METHOD FOR TREATING DISEASES Download PDF

Info

Publication number
RU2006127134A
RU2006127134A RU2006127134/14A RU2006127134A RU2006127134A RU 2006127134 A RU2006127134 A RU 2006127134A RU 2006127134/14 A RU2006127134/14 A RU 2006127134/14A RU 2006127134 A RU2006127134 A RU 2006127134A RU 2006127134 A RU2006127134 A RU 2006127134A
Authority
RU
Russia
Prior art keywords
patient
treating diseases
fragmented dna
dna
amount
Prior art date
Application number
RU2006127134/14A
Other languages
Russian (ru)
Other versions
RU2322264C1 (en
Inventor
Михаил Аркадьевич Шурдов (RU)
Михаил Аркадьевич Шурдов
Сергей Станиславович Богачев (RU)
Сергей Станиславович Богачев
Леонид Анатольевич Якубов (RU)
Леонид Анатольевич ЯКУБОВ
Владимир Алексеевич Рогачев (RU)
Владимир Алексеевич Рогачев
Валерий Петрович Николин (RU)
Валерий Петрович Николин
Нелли Александровна Попова (RU)
Нелли Александровна Попова
Анастаси Сергеевна Лихачева (RU)
Анастасия Сергеевна Лихачева
Тамара Егоровна Себелева (RU)
Тамара Егоровна Себелева
Александр Геннадиевич Шилов (RU)
Александр Геннадиевич Шилов
Наталь Сергеевна Жданова (RU)
Наталья Сергеевна Жданова
Людмила Васильевна Мечетина (RU)
Людмила Васильевна Мечетина
Оксана В чеславовна Врацких (RU)
Оксана Вячеславовна Врацких
Сергей Николаевич Серегин (RU)
Сергей Николаевич Серегин
Елена Рэмовна Черных (RU)
Елена Рэмовна Черных
Евгений Львович Гельфгат (RU)
Евгений Львович Гельфгат
Original Assignee
Михаил Аркадьевич Шурдов (RU)
Михаил Аркадьевич Шурдов
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Михаил Аркадьевич Шурдов (RU), Михаил Аркадьевич Шурдов filed Critical Михаил Аркадьевич Шурдов (RU)
Priority to RU2006127134/14A priority Critical patent/RU2322264C1/en
Priority to PCT/RU2007/000007 priority patent/WO2008013473A1/en
Priority to CN2007800283047A priority patent/CN101495157B/en
Publication of RU2006127134A publication Critical patent/RU2006127134A/en
Application granted granted Critical
Publication of RU2322264C1 publication Critical patent/RU2322264C1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (1)

Способ лечения заболеваний, основанный на введении в организм пациента фрагментированной ДНК, отличающийся тем, что фрагментированная ДНК является аллогенной и состоит из фрагментов, длина которых соответствует 1-10 нуклеосомным единицам, составляющих полный геном пациента в ассоциации с белками ядерного матрикса, при этом количество фрагментированной ДНК принимают равным или превышающим количество собственно ДНК плазмы крови и тканевых жидкостей пациента, но не более 1500 нг/мл.A method of treating diseases based on the introduction of fragmented DNA into the patient’s body, characterized in that the fragmented DNA is allogeneic and consists of fragments whose length corresponds to 1-10 nucleosome units that make up the patient’s complete genome in association with nuclear matrix proteins, the amount of fragmented DNA is taken equal to or greater than the amount of DNA in the blood plasma and tissue fluids of the patient, but not more than 1500 ng / ml.
RU2006127134/14A 2006-07-27 2006-07-27 Method for treating diseases RU2322264C1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
RU2006127134/14A RU2322264C1 (en) 2006-07-27 2006-07-27 Method for treating diseases
PCT/RU2007/000007 WO2008013473A1 (en) 2006-07-27 2007-01-11 Disease treating method
CN2007800283047A CN101495157B (en) 2006-07-27 2007-01-11 disease treatment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2006127134/14A RU2322264C1 (en) 2006-07-27 2006-07-27 Method for treating diseases

Publications (2)

Publication Number Publication Date
RU2006127134A true RU2006127134A (en) 2008-02-10
RU2322264C1 RU2322264C1 (en) 2008-04-20

Family

ID=38981715

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006127134/14A RU2322264C1 (en) 2006-07-27 2006-07-27 Method for treating diseases

Country Status (3)

Country Link
CN (1) CN101495157B (en)
RU (1) RU2322264C1 (en)
WO (1) WO2008013473A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013084002A2 (en) * 2011-12-07 2013-06-13 Singapore Volition Pte Limited Method for detecting nucleosome adducts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9402642D0 (en) * 1994-08-05 1994-08-05 Maria Anvret Gene Therapy
RU2234323C1 (en) * 2003-05-27 2004-08-20 Шурдов Михаил Аркадьевич Preparation eliciting antitumor, antitoxic and radioprotecting effect
US7888121B2 (en) * 2003-08-08 2011-02-15 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination

Also Published As

Publication number Publication date
RU2322264C1 (en) 2008-04-20
CN101495157B (en) 2013-02-13
CN101495157A (en) 2009-07-29
WO2008013473A1 (en) 2008-01-31

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Legal Events

Date Code Title Description
PC41 Official registration of the transfer of exclusive right

Effective date: 20141006

MM4A The patent is invalid due to non-payment of fees

Effective date: 20150728

NF4A Reinstatement of patent

Effective date: 20170208

MM4A The patent is invalid due to non-payment of fees

Effective date: 20200728