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RU2004120632A - METHOD FOR COMBINED TREATMENT OF LOCAL DISTRIBUTED MALIGNANT TUMORS OF TRAJA AND / OR BRONCH - Google Patents

METHOD FOR COMBINED TREATMENT OF LOCAL DISTRIBUTED MALIGNANT TUMORS OF TRAJA AND / OR BRONCH Download PDF

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Publication number
RU2004120632A
RU2004120632A RU2004120632/14A RU2004120632A RU2004120632A RU 2004120632 A RU2004120632 A RU 2004120632A RU 2004120632/14 A RU2004120632/14 A RU 2004120632/14A RU 2004120632 A RU2004120632 A RU 2004120632A RU 2004120632 A RU2004120632 A RU 2004120632A
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RU
Russia
Prior art keywords
malignant tumors
combined treatment
traja
bronch
local distributed
Prior art date
Application number
RU2004120632/14A
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Russian (ru)
Other versions
RU2286817C2 (en
Inventor
Марк Львович Гельфонд (RU)
Марк Львович Гельфонд
Андрей Иванович Арсеньев (RU)
Андрей Иванович Арсеньев
Алексей Степанович Барчук (RU)
Алексей Степанович Барчук
Александр Михайлович Щербаков (RU)
Александр Михайлович Щербаков
Сергей Васильевич Канаев (RU)
Сергей Васильевич Канаев
Александр Вениаминович Шулепов (RU)
Александр Вениаминович Шулепов
Original Assignee
ГУН НИИ онкологии им. проф. Н.Н. Петрова Минздрава РФ (RU)
ГУН НИИ онкологии им. проф. Н.Н. Петрова Минздрава РФ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by ГУН НИИ онкологии им. проф. Н.Н. Петрова Минздрава РФ (RU), ГУН НИИ онкологии им. проф. Н.Н. Петрова Минздрава РФ filed Critical ГУН НИИ онкологии им. проф. Н.Н. Петрова Минздрава РФ (RU)
Priority to RU2004120632/14A priority Critical patent/RU2286817C2/en
Publication of RU2004120632A publication Critical patent/RU2004120632A/en
Application granted granted Critical
Publication of RU2286817C2 publication Critical patent/RU2286817C2/en

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Claims (1)

Способ комбинированного лечения местно-распространенных злокачественных опухолей трахеи и/или бронхов, включающий проведение реканализации просвета трахеи и/или бронхов и фотодинамической терапии, отличающийся тем, что производят аргоноплазменную реканализацию при мощности 60-90 Вт с последующей фотодинамической терапией с препаратом "фотодитазин" 0,8-1,2 мг/кг и излучением полупроводникового лазера длиной волны 662 нм и суммарной дозой энергии 400 Дж, затем проводят брахитерапию при длине траектории движения источника 5-20 см, шаге 5 мм и глубине референтной изодозы 10 мм от источника; с обеспечением движения аппликатора выше и ниже опухоли от 1 до 3 см и подведением дозы от 14 до 28 Гр в режиме 1 раз в неделю по 7 Гр и дистанционную лучевую терапию в режиме 5 раз в неделю по 1-2 Гр до СОД доз 45-55 Гр.A method for the combined treatment of locally advanced malignant tumors of the trachea and / or bronchi, including recanalization of the lumen of the trachea and / or bronchi and photodynamic therapy, characterized in that argon plasma recanalization is performed at a power of 60-90 W, followed by photodynamic therapy with photoditazine 0 , 8-1.2 mg / kg and radiation of a semiconductor laser with a wavelength of 662 nm and a total dose of energy of 400 J, then brachytherapy is carried out with a source path of 5-20 cm, a step of 5 mm and a depth inert reference isodose 10 mm from the source; with the provision of the applicator movement above and below the tumor from 1 to 3 cm and dose adjustment from 14 to 28 Gy in the regimen of 1 time per week of 7 Gy and remote radiation therapy in the regime of 5 times a week for 1-2 Gy to SOD doses of 45- 55 gr.
RU2004120632/14A 2004-07-06 2004-07-06 Method for combined therapy of locally metastasing malignant tumors of trachea and/or bronchi RU2286817C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2004120632/14A RU2286817C2 (en) 2004-07-06 2004-07-06 Method for combined therapy of locally metastasing malignant tumors of trachea and/or bronchi

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2004120632/14A RU2286817C2 (en) 2004-07-06 2004-07-06 Method for combined therapy of locally metastasing malignant tumors of trachea and/or bronchi

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RU2004120632A true RU2004120632A (en) 2006-01-10
RU2286817C2 RU2286817C2 (en) 2006-11-10

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RU2004120632/14A RU2286817C2 (en) 2004-07-06 2004-07-06 Method for combined therapy of locally metastasing malignant tumors of trachea and/or bronchi

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2372119C1 (en) * 2008-05-15 2009-11-10 Федеральное государственное учреждение "Научно-исследовательский институт онкологии имени Н.Н. Петрова Федерального агентства по высокотехнологичной медицинской помощи" Method of integrated treatment of locally advanced malignant bronchial and/or tracheal tumours
RU2533979C1 (en) * 2013-03-11 2014-11-27 государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации Method of treating central obstructing tracheal and bronchial tumours
RU2724480C2 (en) * 2019-07-18 2020-06-23 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации" (ФГБУ "НМИЦ радиологии" Минздрава России) Method of combined radiotherapy and photodynamic therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2217183C2 (en) * 2001-04-09 2003-11-27 Государственное учреждение системы высшего и послевузовского профессионального образования "Сибирский государственный медицинский университет" Method for treating the cases of first degree dysplasia (pretumor) changes of bronchial epithelium in patients suffering from nonspecific pulmonary diseases

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RU2286817C2 (en) 2006-11-10

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Effective date: 20080707