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RU2003123066A - NITROXYSUCCINATE 2,4,6-TRIMETHYL-3-OXYPYRIDINE AND METHOD FOR ITS PRODUCTION - Google Patents

NITROXYSUCCINATE 2,4,6-TRIMETHYL-3-OXYPYRIDINE AND METHOD FOR ITS PRODUCTION Download PDF

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Publication number
RU2003123066A
RU2003123066A RU2003123066/04A RU2003123066A RU2003123066A RU 2003123066 A RU2003123066 A RU 2003123066A RU 2003123066/04 A RU2003123066/04 A RU 2003123066/04A RU 2003123066 A RU2003123066 A RU 2003123066A RU 2003123066 A RU2003123066 A RU 2003123066A
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RU
Russia
Prior art keywords
trimethyl
nitroxysuccinate
oxypyridine
production
hydroxypyridine
Prior art date
Application number
RU2003123066/04A
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Russian (ru)
Other versions
RU2250210C1 (en
Inventor
Борис Сергеевич Федоров (RU)
Борис Сергеевич Федоров
Михаил Арсеньевич Фадеев (RU)
Михаил Арсеньевич Фадеев
гин Алексей Михайлович Сип (RU)
Алексей Михайлович Сипягин
Геннадий Николаевич Богданов (RU)
Геннадий Николаевич Богданов
Денис Валерьевич Мищенко (RU)
Денис Валерьевич Мищенко
Владислав Николаевич Варфоломеев (RU)
Владислав Николаевич Варфоломеев
Original Assignee
Институт проблем химической физики Российской Академии наук (ИПХФ РАН) (RU)
Институт Проблем Химической Физики Российской Академии Наук (Ипхф Ран)
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Application filed by Институт проблем химической физики Российской Академии наук (ИПХФ РАН) (RU), Институт Проблем Химической Физики Российской Академии Наук (Ипхф Ран) filed Critical Институт проблем химической физики Российской Академии наук (ИПХФ РАН) (RU)
Priority to RU2003123066/04A priority Critical patent/RU2250210C1/en
Publication of RU2003123066A publication Critical patent/RU2003123066A/en
Application granted granted Critical
Publication of RU2250210C1 publication Critical patent/RU2250210C1/en

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  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (2)

1. Нитроксисукцинат 2,4,6-триметил-3-оксипиридина формулы (1)1. Nitroxysuccinate 2,4,6-trimethyl-3-hydroxypyridine of the formula (1)
Figure 00000001
Figure 00000001
 2. Способ получения нитроксисукцината 2,4,6-триметил-3-оксипиридина, заключающийся в том, что яблочную кислоту нитруют смесью серной и азотной кислот, затем отделяют нитроксиянтарную кислоту и обрабатывают ее 2,4.6-триметил-3-оксипиридином с последующим выделением целевого продукта.2. A method of producing 2,4,6-trimethyl-3-hydroxypyridine nitroxysuccinate, which is that the malic acid is nitrated with a mixture of sulfuric and nitric acids, then nitroxy succinic acid is separated and treated with 2,4.6-trimethyl-3-hydroxypyridine, followed by isolation target product.
RU2003123066/04A 2003-07-25 2003-07-25 2,4,6-trimethyl-3-oxypyridine nitrosuccinate and method for production thereof RU2250210C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2003123066/04A RU2250210C1 (en) 2003-07-25 2003-07-25 2,4,6-trimethyl-3-oxypyridine nitrosuccinate and method for production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2003123066/04A RU2250210C1 (en) 2003-07-25 2003-07-25 2,4,6-trimethyl-3-oxypyridine nitrosuccinate and method for production thereof

Publications (2)

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RU2003123066A true RU2003123066A (en) 2005-02-20
RU2250210C1 RU2250210C1 (en) 2005-04-20

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Publication number Priority date Publication date Assignee Title
RU2276138C2 (en) * 2004-05-12 2006-05-10 Марвел Лайф Сайнсез Лтд. Substance possessing antioxidant, geroprotecting and anti-ischemic activity and method for its preparing
RU2311180C2 (en) * 2005-04-28 2007-11-27 Галина Викторовна Сукоян Agent for preventing progression of apoptotic and arresting necrotic alterations in body tissue
RU2326665C1 (en) * 2007-04-03 2008-06-20 Марвел ЛайфСайнсез Лимитед, Великобритания Medicinal agent with antihypoxic, antistroke, memory-refining action
EA011238B1 (en) * 2007-04-03 2009-02-27 Марвел Лайфсайнсез Лтд. A substance having anti-hypoxic, anti-apoplexy, improving memory activity
RU2460529C1 (en) * 2011-06-30 2012-09-10 Елена Геннадьевна Цублова Drug possessing actoprotective, antihypoxic, neuroprotective, antiamnestic and thermoprotective activity

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IT1247528B (en) * 1991-04-24 1994-12-17 Medea Res Srl THERAPEUTIC ACTIVITY COMPOUND, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20090726

NF4A Reinstatement of patent

Effective date: 20120910

MM4A The patent is invalid due to non-payment of fees

Effective date: 20170726

NF4A Reinstatement of patent

Effective date: 20181106