RU1826910C - Biostimulating agent - Google Patents

Abstract

Usage: in medicine, namely in pharmacology. Essence: the product further comprises extracts of leuzea, licorice and honey in the following ratio of components, wt.%: Extract of the root of leuzea (dry) 1.2-6.0; Eleutherococcus root extract (dry 1.2-6.0); licorice root extract (dry) 2.0-5.0; natural honey the rest. In addition, the tool may additionally contain propolis extract and pollen in equal amounts of 1.5-5.4 wt.%. Positive effect: the tool increases the protective functions of the body to the action of nonspecific complex damaging factors. 1 tab.

Description

The invention relates to the field of pharmacology and can be used in medical practice to stimulate the endocrine system, sex glands, normalize the activity of the gastrointestinal tract, increase the body's resistance to complex nonspecific damaging factors, including radiation.

The aim of the invention is to increase the efficiency and specificity of the action of a pharmaceutical product, to enhance its protective effect on the effect on the body of nonspecific complex damaging factors, in particular radiation.

The goal is achieved in that the claimed product contains, in addition to the extract of Eleutherococcus, honey, extracts of propolis, roots and rhizomes of licorice, root of the lewsee and pollen. The components of the agent are in the ratio, wt.%: Eleutherococcus extract 1.2-6.0; Leuzea extract 1.2-6.0; licorice extract 2.0-5.0; propolis extract 1.5-5.4; pollen 1., 4; honey the rest.

The proposed method has the following distinctive features:

1) Honey is used as a solvent in this composition. It provides full compatibility of the extracts, masks their unpleasant taste, and has a protective effect on flzvoidoids, phenolic acids and other phenolic compounds - ingredients of medicinal plant extracts.

Honey somewhat slows down the absorption of the composition in the intestines. To compensate for this effect, propolis and pollen are added to the honey. The latter contain mineral salts and vitamins that regulate the absorption process and improve the pharmacokinetic properties of the composition.

2) A mixture of these extracts has a stronger protective effect on the action of nonspecific damaging factors than eleutherococcus and other separately taken extracts. When displaced, a synergistic effect appears.

PRI me R 1. Preparation of the composition. In a mechanical mixture of honey, pollen, propolis, taken in the indicated ratios

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Alternately thick aqueous or dry extracts of licorice root, eleutherococcus, and leuzea are added. The concentration of the extracts is taken such that, after application of the latter, the amount of water in honey exceeded 50 ml per 1 kg of the mixture.

Example 2. Testing the effect of increasing the body's resistance to the action of nonspecific damaging factors. The test was carried out in vitro by measuring the antioxidant activity by chemiluminescence. Liposomes were used as a model. Phytometoproduct and similar mixtures were tested in the concentration range 15–40 g / ml. The results of the experiments are shown in the table.

The effect of the claimed phytomedomedicine is higher than that of each of the individual honey extract mixtures.

Example 3. Clinical trials of a biostimulating agent. Tests of the biostimulating agent were carried out on two groups of subjects. The first group consisted of children 7-13 years old (80 people) suffering from chronic diseases of the ENT organs, respiratory tract, and kidneys, accompanied by exacerbations in the autumn-winter period.

It was established that prophylactic administration of the product for 9-11 days (3 times a day for one tablespoon) in the group significantly reduced the number of diseases (up to 7 people; in the control group - 29 people; in the group receiving multivitamin preparations - 17 people) .

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Tests of bioproduct in a group of patients (39 people) who suffered as a result of the Chernobyl accident; An improvement in the psychological state was revealed by increasing tone, reducing depression, normalizing the process of falling asleep, eliminating insomnia and increased irritability, and lengthening sleep.

Bioproduct increased resistance to colds, increasing the activity of the pituitary adrenal system, some immunological parameters.

In no case were manifestations of intolerance to the product, the occurrence of side effects.

Claims (3)

1. Biostimulating agent containing eleutherococcus extract, characterized in that, in order to increase the protective functions of the body to the action of nonspecific complex damaging factors, the agent additionally contains extracts of leuzea, licorice root and honey in the following ratio of components, wt.%: Leuzea extract (dry) 1.2-6.0 Eleutherococcus extract (dry) 1.2-6.0 Corn extract licorice (dry) 2.0-5.0 Honey rest 2. Means pop, 1, characterized in that it additionally contains propolis extract and pollen in equal amounts of 1.5-5.4, wt.%. Antioxidant activity of medical products depending on their composition. The composition of the medical product 1.. Levzea root extract 3% 2. Eleutherococcus extract 5% Z. Natural honey 92% 1. Licorice root extract 0.5% 2. Eleutherococcus extract 0.5% 3. Levzea root extract 0.5% 3, Honey natural 98.5% 1. Licorice root extract 2.0% 2. Eleutherococcus extract 1.2% 3. Levzea root extract 1.2% Z. Natural honey 95.6% 1. Licorice root extract 5.0% 2. Eleutherococcus extract 6.0% 3.Leux root extract 6.0% Z. Natural honey 83.0% 1. Licorice root extract 3.0% 2. Eleutherococcus extract 3.0% 3.Leux root extract 3.0% Z. Natural honey 91.0%  - All formulations contain 3 g of propolis and 3 g of pollen per 100 g of the finished product;  - Dry extract;  - Thick aqueous extract in terms of dry matter. Table continuation Antioxidant activity (constant inhibition of luminescence ig 1 8.3-8.6 9.0 - 9.2 14.1 -14.7 15.2 - 15.3 13.7-14.0