RO71305A - Procede pour la preparation des d-halo-6-methyle-2,8-cyano-(carboxamido)ergolines - Google Patents

Procede pour la preparation des d-halo-6-methyle-2,8-cyano-(carboxamido)ergolines

Info

Publication number: RO71305A
Authority: RO; Romania
Prior art keywords: geroline; carboxamido; halo; cyano; methyl
Prior art date: 1972-07-21

Application number

RO7375548A

Other languages

English (en)

Romanian (ro)

Inventor

James A Clemens

Edmund C Komfeld

Nicholas J Bach

Original Assignee

Eli Lilly And Co,Us

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-07-21

Filing date

1973-07-20

Publication date

1982-03-24

1973-07-20 Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us

1982-03-24 Publication of RO71305A publication Critical patent/RO71305A/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

RO7375548A 1972-07-21 1973-07-20 Procede pour la preparation des d-halo-6-methyle-2,8-cyano-(carboxamido)ergolines RO71305A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US27390272A	1972-07-21	1972-07-21

Publications (1)

Publication Number	Publication Date
RO71305A true RO71305A (fr)	1982-03-24

Family

ID=23045910

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
RO7300083213A RO63792A (fr)	1972-07-21	1973-07-20	Procede pour la preparation d'ergolines-0-6-methyle-2-8-substituees
RO7375548A RO71305A (fr)	1972-07-21	1973-07-20	Procede pour la preparation des d-halo-6-methyle-2,8-cyano-(carboxamido)ergolines

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
RO7300083213A RO63792A (fr)	1972-07-21	1973-07-20	Procede pour la preparation d'ergolines-0-6-methyle-2-8-substituees

Country Status (24)

Country	Link
JP (2)	JPS576431B2 (fr)
AR (3)	AR206772A1 (fr)
AT (1)	AT331425B (fr)
BE (1)	BE802531A (fr)
BG (3)	BG21411A3 (fr)
CA (1)	CA1006159A (fr)
CH (5)	CH580626A5 (fr)
CS (1)	CS208164B2 (fr)
DD (1)	DD107690A5 (fr)
DE (2)	DE2365974A1 (fr)
DK (1)	DK140986B (fr)
ES (5)	ES417078A1 (fr)
FR (1)	FR2193606B1 (fr)
GB (1)	GB1423065A (fr)
HU (1)	HU167274B (fr)
IE (1)	IE37936B1 (fr)
IL (3)	IL42730A (fr)
NL (1)	NL7309969A (fr)
PH (1)	PH11229A (fr)
RO (2)	RO63792A (fr)
SE (3)	SE393111B (fr)
SU (3)	SU645581A3 (fr)
YU (1)	YU36953B (fr)
ZA (1)	ZA734627B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1517971A (en) *	1974-07-19	1978-07-19	Sandoz Ltd	8alpha-substituted ergoline i derivatives
US3968111A (en) *	1974-12-06	1976-07-06	Eli Lilly And Company	8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) *	1978-09-08	1983-01-27	Farmitalia Carlo Erba S.P.A.	Ergoline derivatives
EP0160842B1 (fr) *	1984-04-09	1994-06-22	Schering Aktiengesellschaft	Dérivés d'ergoline substitués sur la position 2, procédés pour leur préparation et leur utilisation comme médicaments
HU196598B (en) *	1986-04-25	1988-12-28	Richter Gedeon Vegyeszet	Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (de) *	1986-06-16	1987-12-17	Schering Ag	1-und/oder 2-substituierte ergolinderivate
JPH0596382U (ja) *	1992-05-28	1993-12-27	イビデン株式会社	ドアユニット

1973
- 1973-01-01 AR AR249167A patent/AR206772A1/es active
- 1973-07-10 ZA ZA734627A patent/ZA734627B/xx unknown
- 1973-07-10 GB GB3289073A patent/GB1423065A/en not_active Expired
- 1973-07-12 SE SE7309781A patent/SE393111B/xx unknown
- 1973-07-12 IL IL42730A patent/IL42730A/en unknown
- 1973-07-12 IL IL48288A patent/IL48288A/en unknown
- 1973-07-13 DE DE2365974A patent/DE2365974A1/de not_active Withdrawn
- 1973-07-13 DE DE2335750A patent/DE2335750C3/de not_active Expired
- 1973-07-17 YU YU1945/73A patent/YU36953B/xx unknown
- 1973-07-17 NL NL7309969A patent/NL7309969A/xx not_active Application Discontinuation
- 1973-07-18 PH PH14835A patent/PH11229A/en unknown
- 1973-07-19 DK DK399873AA patent/DK140986B/da unknown
- 1973-07-19 HU HUEI485A patent/HU167274B/hu unknown
- 1973-07-19 BE BE1005246A patent/BE802531A/fr not_active IP Right Cessation
- 1973-07-20 CH CH391276A patent/CH580626A5/xx not_active IP Right Cessation
- 1973-07-20 BG BG26855A patent/BG21411A3/xx unknown
- 1973-07-20 ES ES417078A patent/ES417078A1/es not_active Expired
- 1973-07-20 CH CH391176A patent/CH578563A5/xx not_active IP Right Cessation
- 1973-07-20 AT AT643473A patent/AT331425B/de not_active IP Right Cessation
- 1973-07-20 DD DD172402A patent/DD107690A5/xx unknown
- 1973-07-20 SU SU731948966A patent/SU645581A3/ru active
- 1973-07-20 CH CH391076A patent/CH580625A5/xx not_active IP Right Cessation
- 1973-07-20 CH CH391376A patent/CH578564A5/xx not_active IP Right Cessation
- 1973-07-20 BG BG024148A patent/BG21410A3/xx unknown
- 1973-07-20 CH CH1067873A patent/CH581135A5/xx not_active IP Right Cessation
- 1973-07-20 RO RO7300083213A patent/RO63792A/fr unknown
- 1973-07-20 FR FR7326708A patent/FR2193606B1/fr not_active Expired
- 1973-07-20 IE IE1238/73A patent/IE37936B1/xx unknown
- 1973-07-20 CA CA177,021A patent/CA1006159A/en not_active Expired
- 1973-07-20 BG BG028443A patent/BG22400A3/xx unknown
- 1973-07-20 RO RO7375548A patent/RO71305A/fr unknown
- 1973-07-20 CS CS735239A patent/CS208164B2/cs unknown
- 1973-07-20 JP JP8074973A patent/JPS576431B2/ja not_active Expired
1974
- 1974-01-01 AR AR252738A patent/AR206887A1/es active
- 1974-12-04 SU SU7402080295A patent/SU584780A3/ru active
1975
- 1975-01-14 SU SU7502098198A patent/SU575029A3/ru active
- 1975-01-30 AR AR257473A patent/AR210072A1/es active
- 1975-10-13 IL IL48288A patent/IL48288A0/xx unknown
- 1975-11-21 ES ES442886A patent/ES442886A1/es not_active Expired
- 1975-11-21 ES ES442887A patent/ES442887A1/es not_active Expired
- 1975-11-21 ES ES442885A patent/ES442885A1/es not_active Expired
1976
- 1976-04-07 ES ES446789A patent/ES446789A1/es not_active Expired
- 1976-10-15 SE SE7611467A patent/SE410603B/xx unknown
- 1976-10-15 SE SE7611466A patent/SE410459B/xx unknown
1981
- 1981-08-07 JP JP56123937A patent/JPS5813541B2/ja not_active Expired

Also Published As

Publication number	Publication date
BG21411A3 (fr)	1976-05-20
SE7611467L (sv)	1976-10-15
NL7309969A (fr)	1974-01-23
DE2335750C3 (de)	1978-10-19
AR210072A1 (es)	1977-06-30
DE2335750A1 (de)	1974-02-14
ES446789A1 (es)	1977-06-01
SE393111B (sv)	1977-05-02
IL48288A (en)	1976-06-30
CH580626A5 (fr)	1976-10-15
CH580625A5 (fr)	1976-10-15
ZA734627B (en)	1974-06-26
IL48288A0 (en)	1975-12-31
AT331425B (de)	1976-08-25
JPS576431B2 (fr)	1982-02-04
CH578564A5 (fr)	1976-08-13
DK140986B (da)	1979-12-17
DE2335750B2 (de)	1978-02-23
SU584780A3 (ru)	1977-12-15
DD107690A5 (fr)	1974-08-12
SU645581A3 (ru)	1979-01-30
CS208164B2 (en)	1981-08-31
ES442887A1 (es)	1977-05-16
BG21410A3 (bg)	1976-05-20
IE37936B1 (en)	1977-11-23
BG22400A3 (bg)	1977-02-20
IL42730A0 (en)	1973-10-25
PH11229A (en)	1977-10-28
AR206772A1 (es)	1976-08-23
HU167274B (fr)	1975-09-27
AR206887A1 (es)	1976-08-31
JPS4985099A (fr)	1974-08-15
SU575029A3 (ru)	1977-09-30
GB1423065A (en)	1976-01-28
ES442886A1 (es)	1977-04-16
DE2365974A1 (de)	1977-03-24
BE802531A (fr)	1974-01-21
IL42730A (en)	1976-06-30
DK140986C (fr)	1980-07-21
YU36953B (en)	1984-08-31
CH578563A5 (fr)	1976-08-13
ATA643473A (de)	1975-11-15
JPS5813541B2 (ja)	1983-03-14
SE7611466L (sv)	1976-10-15
JPS5781487A (en)	1982-05-21
ES417078A1 (es)	1976-05-01
SE410459B (sv)	1979-10-15
YU194573A (en)	1982-06-18
FR2193606B1 (fr)	1977-07-15
FR2193606A1 (fr)	1974-02-22
SE410603B (sv)	1979-10-22
ES442885A1 (es)	1977-04-16
RO63792A (fr)	1978-12-15
CH581135A5 (fr)	1976-10-29
CA1006159A (en)	1977-03-01
AU5792673A (en)	1975-01-16
IE37936L (en)	1974-01-21

Similar Documents

Publication	Publication Date	Title
RO67479A (fr)	1981-06-21	Procede pour la preparation des pleuromutilines
IT998245B (it)	1976-01-20	Proccesso per la preparazione di novolacche
NO741223L (no)	1974-10-22	Fremgangsmåte for fremstilling av 6-deoksytetracykliner.
RO71305A (fr)	1982-03-24	Procede pour la preparation des d-halo-6-methyle-2,8-cyano-(carboxamido)ergolines
DK134604B (da)	1976-12-06	Fremgangsmåde til fremstilling af indenyl-3-acetoglucuronider.
BG20596A3 (bg)	1975-12-05	Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазини
RO69492A2 (fr)	1980-06-16	Procede pour la preparation de perchlore-methyle-mercaptane
FI52735C (fi)	1977-11-10	Menetelmä uusien pregnadieeni-21-happojohdannaisten valmistamiseksi.
BG22815A3 (bg)	1977-04-20	Метод за получаване на 2,6-диамино-дихидропиридини
DK132233B (da)	1975-11-10	Fremgangsmåde til fremstilling af antibiotikum A-2315.
FI53452C (fi)	1978-05-10	Foerfarande foer framstaellning av n-laegre-alkyl-1,4-dihydro-4-oxokinolin-3-karboxylsyror
DK131575B (da)	1975-06-04	Analogifremgangsmåde til fremstilling af 2beta-hydroxy-3alfa-aminosteroider.
DK138645B (da)	1978-10-09	Analogifremgangsmåde til fremstilling af sulfamoylfenyl-imidazolidiner.
DK131864B (da)	1975-09-15	Fremgangsmåde til fremstilling af pregnan-21-syrederivater.
DK135166B (da)	1977-03-14	Analogifremgangsmåde til fremstilling af 2-methyl-5-nitro-imidazoler.
DK132410B (da)	1975-12-01	Analogifremgangsmåde til fremstilling af 2-amino-4H-pyraner.
DK129657B (da)	1974-11-04	Analogifremgangsmåde til fremstilling af 3-methylpyrazol-5-carboxamider.
RO64462A (fr)	1980-06-15	Procede pour la preparation du magnesie syntherisee
RO65994A (fr)	1980-02-15	Procede pour la preparation des diaminobenzophenones
BG19804A3 (bg)	1975-10-10	Метод за получаване на 4-или-5-нитроимидазоли
BG20795A3 (bg)	1975-12-20	Метод за получаване на триазинобензимидазоли
DK139677B (da)	1979-03-26	Fremgangsmåde til fremstilling af 7-benzoylindolin-2-oner.
DK139225B (da)	1979-01-15	Fremgangsmåde til fremstilling af morphanthridiner.
DK134236B (da)	1976-10-04	Analogifremgangsmåde til fremstilling af 3-cycloalkoxy-16alfa-cyanopregn-5-en-20-oner.
AR202282A1 (es)	1975-05-30	Procedimiento de produccion de nitro-2-benzofuranos