PT99057A - Processo para a preparacao de composicoes farmaceuticas contendo uma mistura sinergica de glicoproteina cd4 da superficie das ceelulas ou de um seu analogo com um agente polianionico anti-hiv, nomeadamente um polissacarido sulfatado - Google Patents
Processo para a preparacao de composicoes farmaceuticas contendo uma mistura sinergica de glicoproteina cd4 da superficie das ceelulas ou de um seu analogo com um agente polianionico anti-hiv, nomeadamente um polissacarido sulfatadoInfo
- Publication number
- PT99057A PT99057A PT99057A PT9905791A PT99057A PT 99057 A PT99057 A PT 99057A PT 99057 A PT99057 A PT 99057A PT 9905791 A PT9905791 A PT 9905791A PT 99057 A PT99057 A PT 99057A
- Authority
- PT
- Portugal
- Prior art keywords
- agent
- hiv
- pct
- polynostain
- ecelulas
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000036436 anti-hiv Effects 0.000 title abstract 2
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000002195 synergetic effect Effects 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 229920001353 Dextrin Polymers 0.000 abstract 3
- 239000004375 Dextrin Substances 0.000 abstract 3
- 235000019425 dextrin Nutrition 0.000 abstract 3
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 3
- 241000713772 Human immunodeficiency virus 1 Species 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/02—Esters
- C08B31/06—Esters of inorganic acids
- C08B31/063—Starch sulfates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909020861A GB9020861D0 (en) | 1990-09-25 | 1990-09-25 | Pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT99057A true PT99057A (pt) | 1992-08-31 |
| PT99057B PT99057B (pt) | 1999-02-26 |
Family
ID=10682722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99057A PT99057B (pt) | 1990-09-25 | 1991-09-25 | Processo para a preparacao de composicoes farmaceuticas contendo uma mistura sinergica de glicoproteina cd4 da superficie das ceelulas ou de um seu analogo com um agente polianionico anti-hiv, nomeadamente um polissacarido sulfatado |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5439892A (pt) |
| EP (1) | EP0550532B1 (pt) |
| JP (1) | JP3281373B2 (pt) |
| AT (1) | ATE165005T1 (pt) |
| AU (1) | AU649731B2 (pt) |
| CA (1) | CA2092094C (pt) |
| DE (1) | DE69129272T2 (pt) |
| DK (1) | DK0550532T3 (pt) |
| ES (1) | ES2113888T3 (pt) |
| GB (1) | GB9020861D0 (pt) |
| IE (1) | IE913340A1 (pt) |
| NZ (1) | NZ239908A (pt) |
| PT (1) | PT99057B (pt) |
| WO (1) | WO1992004904A1 (pt) |
| ZA (1) | ZA917597B (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9625193D0 (en) * | 1996-12-04 | 1997-01-22 | Ml Lab Plc | Treatment of highly vascular tumours |
| ATE317703T1 (de) * | 1997-06-12 | 2006-03-15 | Innovata Plc | Polymer-wirkstoff-konjugate zur behandlung von krebs |
| US6077503A (en) * | 1997-07-30 | 2000-06-20 | Amway Corporation | Skin whitener composition containing mercaptodextran |
| US6821958B1 (en) | 2001-03-06 | 2004-11-23 | Roger K. Hershline | Antiviral composition |
| US20050209189A1 (en) * | 2001-03-06 | 2005-09-22 | Roger Hershline | Antiviral composition |
| AU2002358222A1 (en) * | 2001-12-24 | 2003-07-15 | Ml Laboratories Plc | Composition comprising dextrinsulfate for the treatment of sexual transmitted diseases (std) |
| US20040009953A1 (en) * | 2002-01-10 | 2004-01-15 | Comper Wayne D. | Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof |
| US20030181416A1 (en) * | 2002-01-10 | 2003-09-25 | Comper Wayne D. | Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof |
| WO2004064850A1 (en) * | 2003-01-23 | 2004-08-05 | Ml Laboratories Plc | Antiviral composition comprising a sulphated glucose polymer and a bacteriostatic agent |
| WO2005004882A1 (en) * | 2003-07-09 | 2005-01-20 | Monash University | Antiviral charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and methods of use thereof |
| US7285582B2 (en) * | 2004-12-30 | 2007-10-23 | Conocophillips Company | Modified latex drag reducer and processes therefor and therewith |
| US20070225191A1 (en) * | 2006-03-27 | 2007-09-27 | The Procter & Gamble Company | Methods for modifying bioplymers in ionic liquids |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2967178A (en) * | 1957-12-06 | 1961-01-03 | Corn Products Co | Method of producing gelling starch of high clarity |
| US3017407A (en) * | 1958-08-18 | 1962-01-16 | Riker Laboratories Inc | Process for producing polysulfuric acid esters of polysaccharides |
| US3070595A (en) * | 1960-10-28 | 1962-12-25 | Riker Laboratories Inc | Process for producing polysulfuric acid esters of polysaccharides |
| DE3601136A1 (de) * | 1986-01-16 | 1987-07-23 | Max Planck Gesellschaft | Hemmstoffe der reversen transkriptase fuer prophylaxe und therapie von retrovirus-infektionen in saeugetieren |
| EP0240098A3 (en) * | 1986-04-04 | 1989-05-10 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Oligo and polysaccharides for the treatment of diseases caused by retroviruses |
| SE453394B (sv) * | 1986-07-07 | 1988-02-01 | Pharmacia Ab | Forfarande for framstellning av sulfaterade polysackarider genom anvendning av ett reducerande medel for sulfateringsreaktionen |
| WO1989003684A1 (fr) * | 1987-10-30 | 1989-05-05 | Chugai Seiyaku Kabushiki Kaisha | Agent anti-vih |
| GB9001687D0 (en) * | 1990-01-25 | 1990-03-28 | Ml Lab Plc | Treatment of poisoning and composition for use therein |
| US5221669A (en) * | 1991-04-19 | 1993-06-22 | The United States Of America As Represented By The Department Of Health And Human Services | Antiviral compositions containing α-cyclodextrin sulfates alone and in combination with other known antiviral agents and glucocorticoids and methods of treating viral infections |
-
1990
- 1990-09-25 GB GB909020861A patent/GB9020861D0/en active Pending
-
1991
- 1991-09-23 CA CA002092094A patent/CA2092094C/en not_active Expired - Fee Related
- 1991-09-23 WO PCT/GB1991/001628 patent/WO1992004904A1/en not_active Ceased
- 1991-09-23 AT AT91916848T patent/ATE165005T1/de not_active IP Right Cessation
- 1991-09-23 DK DK91916848T patent/DK0550532T3/da active
- 1991-09-23 EP EP91916848A patent/EP0550532B1/en not_active Expired - Lifetime
- 1991-09-23 DE DE69129272T patent/DE69129272T2/de not_active Expired - Fee Related
- 1991-09-23 US US08/030,227 patent/US5439892A/en not_active Expired - Fee Related
- 1991-09-23 NZ NZ239908A patent/NZ239908A/xx not_active IP Right Cessation
- 1991-09-23 ES ES91916848T patent/ES2113888T3/es not_active Expired - Lifetime
- 1991-09-23 AU AU86145/91A patent/AU649731B2/en not_active Ceased
- 1991-09-23 JP JP51528291A patent/JP3281373B2/ja not_active Expired - Fee Related
- 1991-09-24 IE IE334091A patent/IE913340A1/en not_active IP Right Cessation
- 1991-09-24 ZA ZA917597A patent/ZA917597B/xx unknown
- 1991-09-25 PT PT99057A patent/PT99057B/pt not_active IP Right Cessation
-
1995
- 1995-03-24 US US08/410,067 patent/US6015799A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0550532A1 (en) | 1993-07-14 |
| DE69129272T2 (de) | 1998-11-12 |
| PT99057B (pt) | 1999-02-26 |
| AU649731B2 (en) | 1994-06-02 |
| ES2113888T3 (es) | 1998-05-16 |
| ZA917597B (en) | 1992-05-27 |
| DE69129272D1 (de) | 1998-05-20 |
| CA2092094C (en) | 2004-08-10 |
| DK0550532T3 (da) | 1999-03-08 |
| US5439892A (en) | 1995-08-08 |
| ATE165005T1 (de) | 1998-05-15 |
| GB9020861D0 (en) | 1990-11-07 |
| AU8614591A (en) | 1992-04-15 |
| JPH06503305A (ja) | 1994-04-14 |
| JP3281373B2 (ja) | 2002-05-13 |
| IE913340A1 (en) | 1992-02-25 |
| EP0550532B1 (en) | 1998-04-15 |
| WO1992004904A1 (en) | 1992-04-02 |
| US6015799A (en) | 2000-01-18 |
| CA2092094A1 (en) | 1992-03-26 |
| NZ239908A (en) | 1993-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920407 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19981112 |
|
| MM3A | Annulment or lapse |
Effective date: 20060512 |