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PT97133A - Processo para a preparacao de derivados da xantina que constituem agentes selectivos receptores da adenosina e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados da xantina que constituem agentes selectivos receptores da adenosina e de composicoes farmaceuticas que os contem

Info

Publication number
PT97133A
PT97133A PT97133A PT9713391A PT97133A PT 97133 A PT97133 A PT 97133A PT 97133 A PT97133 A PT 97133A PT 9713391 A PT9713391 A PT 9713391A PT 97133 A PT97133 A PT 97133A
Authority
PT
Portugal
Prior art keywords
adenosine
preparation
pharmaceutical compositions
compositions containing
xanthine derivatives
Prior art date
Application number
PT97133A
Other languages
English (en)
Other versions
PT97133B (pt
Inventor
Norton Paul Peet
Nelsen Lowell Lentz
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of PT97133A publication Critical patent/PT97133A/pt
Publication of PT97133B publication Critical patent/PT97133B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT97133A 1990-03-26 1991-03-25 Processo para a preparacao de derivados da xantina que constituem agentes selectivos receptores da adenosina e de composicoes farmaceuticas que os contem PT97133B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/499,111 US5047534A (en) 1990-03-26 1990-03-26 Selective adenosine receptor agents

Publications (2)

Publication Number Publication Date
PT97133A true PT97133A (pt) 1991-12-31
PT97133B PT97133B (pt) 1998-07-31

Family

ID=23983864

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97133A PT97133B (pt) 1990-03-26 1991-03-25 Processo para a preparacao de derivados da xantina que constituem agentes selectivos receptores da adenosina e de composicoes farmaceuticas que os contem

Country Status (22)

Country Link
US (1) US5047534A (pt)
EP (1) EP0449175B1 (pt)
JP (1) JP3181305B2 (pt)
KR (1) KR100195368B1 (pt)
CN (1) CN1032815C (pt)
AR (1) AR247887A1 (pt)
AT (1) ATE156130T1 (pt)
AU (1) AU632914B2 (pt)
CA (1) CA2038747C (pt)
DE (1) DE69127010T2 (pt)
DK (1) DK0449175T3 (pt)
ES (1) ES2107431T3 (pt)
FI (1) FI98461C (pt)
GR (1) GR3025135T3 (pt)
HU (1) HU208824B (pt)
IE (1) IE910982A1 (pt)
IL (1) IL97656A (pt)
NO (1) NO177591C (pt)
NZ (1) NZ237484A (pt)
PH (1) PH27511A (pt)
PT (1) PT97133B (pt)
ZA (1) ZA912038B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208240A (en) * 1991-03-12 1993-05-04 Merrell Dow Pharmaceuticals Inc. 8-substituted purines as selective adenosine receptor agents
DE69331843T2 (de) * 1992-07-08 2002-09-26 Kyowa Hakko Kogyo Co., Ltd. Xanthine-Derivate als Antidepressiva
ES2120025T3 (es) * 1993-02-26 1998-10-16 Merrell Pharma Inc Derivados de xantina utilizados como antagonistas de receptores de adenosina a1.
AU6781194A (en) * 1993-05-03 1994-11-21 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
HUT72327A (en) * 1993-05-06 1996-04-29 Merrell Pharma Inc 8-substituted xanthines as selective adenosine receptor agents
US5629298A (en) * 1995-03-13 1997-05-13 University Of Massachusetts Medical Center Adenosine as a positive inotrop in the compromised heart
GB9819382D0 (en) 1998-09-04 1998-10-28 Cerebrus Ltd Chemical compounds I
US6258794B1 (en) 1999-12-14 2001-07-10 The Mclean Hospital Corporation Treatment of mental conditions including depression
KR20060037252A (ko) 2003-06-10 2006-05-03 교와 핫꼬 고교 가부시끼가이샤 불안 장애의 치료 방법
WO2007036491A1 (de) * 2005-09-30 2007-04-05 Basf Aktiengesellschaft Verfahren zur herstellung von alpha-substituierten carbonsäuren
US7592461B2 (en) * 2005-12-21 2009-09-22 Bristol-Myers Squibb Company Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1435916A (en) * 1972-05-11 1976-05-19 Beecham Group Ltd Pharmaceutical weight-reducing compositions
SE416810C (sv) * 1977-10-14 1982-07-19 Draco Ab Forfarande for framstellning av xantinderivat med antiallergisk aktivitet
JPS57198544A (en) * 1981-05-28 1982-12-06 Sony Corp Manufacture of magnetic recording medium
US4593095A (en) * 1983-02-18 1986-06-03 The Johns Hopkins University Xanthine derivatives
US4772607A (en) * 1986-05-20 1988-09-20 Warner-Lambert Company Dialkenyl derivatives of xanthine, pharmaceutical compositions and methods of use therefor
US4783530A (en) * 1986-11-13 1988-11-08 Marion Laboratories, Inc. 8-arylxanthines
DE8817122U1 (de) * 1988-12-22 1993-02-04 Boehringer Ingelheim Kg, 55218 Ingelheim Neue Xanthinderivate mit Adenosinantogenistischer Wirkung

Also Published As

Publication number Publication date
NZ237484A (en) 1993-10-26
PH27511A (en) 1993-08-18
IE910982A1 (en) 1991-10-09
DK0449175T3 (da) 1998-02-23
NO177591C (no) 1995-10-18
KR100195368B1 (ko) 1999-06-15
IL97656A0 (en) 1992-06-21
HU208824B (en) 1994-01-28
FI911420A0 (fi) 1991-03-25
DE69127010T2 (de) 1997-11-13
FI98461B (fi) 1997-03-14
KR910016752A (ko) 1991-11-05
NO911200L (no) 1991-09-27
CA2038747A1 (en) 1991-09-27
NO177591B (no) 1995-07-10
JPH04221384A (ja) 1992-08-11
NO911200D0 (no) 1991-03-25
IL97656A (en) 1996-06-18
US5047534A (en) 1991-09-10
FI98461C (fi) 1997-06-25
FI911420L (fi) 1991-09-27
CN1032815C (zh) 1996-09-18
EP0449175A3 (en) 1993-01-20
CN1055181A (zh) 1991-10-09
ES2107431T3 (es) 1997-12-01
AR247887A1 (es) 1995-04-28
AU632914B2 (en) 1993-01-14
CA2038747C (en) 2002-05-28
DE69127010D1 (de) 1997-09-04
ZA912038B (en) 1991-12-24
GR3025135T3 (en) 1998-02-27
PT97133B (pt) 1998-07-31
ATE156130T1 (de) 1997-08-15
EP0449175A2 (en) 1991-10-02
HUT56570A (en) 1991-09-30
JP3181305B2 (ja) 2001-07-03
AU7353791A (en) 1991-10-03
EP0449175B1 (en) 1997-07-30

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910926

FG3A Patent granted, date of granting

Effective date: 19980421

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20031031