PT94377A - Processo de preparacao de acidos imidazolilalcenoicos e de composicoes farmaceuticas que os contem - Google Patents

Processo de preparacao de acidos imidazolilalcenoicos e de composicoes farmaceuticas que os contem

Info

Publication number: PT94377A
Authority: PT; Portugal
Prior art keywords: pharmaceutical compositions; imidazolilcenoic; acids; preparation process; compositions containing
Prior art date: 1989-06-14

Application number

PT94377A

Other languages

English (en)

Other versions

PT94377B (pt

Inventor

Joseph Weinstock

Joseph Alan Finkelstein

Richard Mcculloch Keenan

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-14

Filing date

1990-06-12

Publication date

1991-03-20

1990-06-12 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1991-03-20 Publication of PT94377A publication Critical patent/PT94377A/pt

1997-02-28 Publication of PT94377B publication Critical patent/PT94377B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
External Artificial Organs (AREA)
Polishing Bodies And Polishing Tools (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT94377A 1989-06-14 1990-06-12 Processo de preparacao de acidos imidazolilalcenoicos e de composicoes farmaceuticas que os contem PT94377B (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US36607989A	1989-06-14	1989-06-14
US50641290A	1990-04-06	1990-04-06

Publications (2)

Publication Number	Publication Date
PT94377A true PT94377A (pt)	1991-03-20
PT94377B PT94377B (pt)	1997-02-28

Family

ID=27003220

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT94377A PT94377B (pt)	1989-06-14	1990-06-12	Processo de preparacao de acidos imidazolilalcenoicos e de composicoes farmaceuticas que os contem

Country Status (25)

Country	Link
EP (2)	EP0955294B1 (pt)
JP (1)	JPH0768223B2 (pt)
KR (1)	KR0165837B1 (pt)
CN (2)	CN1027504C (pt)
AT (2)	ATE250587T1 (pt)
CA (1)	CA2018438C (pt)
CY (1)	CY2232B1 (pt)
DE (3)	DE69033469T2 (pt)
DK (2)	DK0955294T3 (pt)
ES (2)	ES2142789T3 (pt)
FI (1)	FI102610B (pt)
GR (1)	GR3033452T3 (pt)
HU (1)	HU208537B (pt)
IE (2)	IE902140A1 (pt)
IL (1)	IL94698A (pt)
LU (1)	LU90562I2 (pt)
MA (1)	MA21896A1 (pt)
NL (1)	NL300006I2 (pt)
NO (1)	NO175977C (pt)
NZ (1)	NZ233997A (pt)
PH (1)	PH27592A (pt)
PL (3)	PL165609B1 (pt)
PT (1)	PT94377B (pt)
SG (1)	SG52330A1 (pt)
ZW (1)	ZW9490A1 (pt)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
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ATE146076T1 (de) *	1990-06-22	1996-12-15	Du Pont	Behandlung des chronischen nierenversagens mit imidazol-angiotensin-ii-rezeptorantagonisten
NZ238688A (en) *	1990-06-28	1992-05-26	Smithkline Beecham Corp	Substituted histidines: pharmaceutical compositions, preparation and uses thereof
NZ239161A (en) *	1990-07-31	1994-01-26	Smithkline Beecham Corp	Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
GB9027197D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
US6028091A (en) *	1990-12-14	2000-02-22	Smithkline Beecham Plc	Medicament
GB9027198D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
GB9027209D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
GB9027212D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
GB9027210D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
GB9027199D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
GB9027211D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
GB9027200D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
GB9027208D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
US6025380A (en) *	1990-12-14	2000-02-15	Smithkline Beecham Plc	Medicament
DE69131021T2 (de) *	1990-12-14	1999-08-12	Smithkline Beecham Corp., Philadelphia, Pa. 19101	Angiotensin-ii-rezeptor blockierende zusammensetzungen
US6034114A (en) *	1990-12-14	2000-03-07	Smithkline Beecham Plc	Medicament
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US5656650A (en) *	1990-12-14	1997-08-12	Smithkline Beecham Corp.	Angiotensin II receptor blocking compositions
GB9027201D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
US5236928A (en) *	1991-03-19	1993-08-17	Merck & Co., Inc.	Imidazole derivatives bearing acidic functional groups at the 5-position, their compositions and methods of use as angiotensin II antagonists
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US5187179A (en) *	1991-03-22	1993-02-16	Merck & Co., Inc.	Angiotensin II antagonists incorporating a substituted imidazo [1,2-b][1,2,4]triazole
US5128327A (en) *	1991-03-25	1992-07-07	Merck & Co., Inc.	Angiotensin II antagonists incorporating a nitrogen containing six membered ring heterocycle
US5177074A (en) *	1991-03-26	1993-01-05	Merck & Co., Inc.	Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5252574A (en) *	1991-04-26	1993-10-12	Merck & Co., Inc.	Angiotensin II antagonists incorporating a substituted thiophene or furan
US5198438A (en) *	1991-05-07	1993-03-30	Merck & Co., Inc.	Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5447949A (en) *	1991-05-15	1995-09-05	Smithkline Beecham Corporation	N-(heteroaryl) imidazolyl-alkenoic acids having angiotension II receptor antagonist activity
GB9110532D0 (en) *	1991-05-15	1991-07-03	Smithkline Beecham Corp	Chemical compounds
GB9110636D0 (en) *	1991-05-16	1991-07-03	Glaxo Group Ltd	Chemical compounds
US5175164A (en) *	1991-06-05	1992-12-29	Merck & Co., Inc.	Angiotensin ii antagonists incorporating a substituted indole or dihydroindole
DE4132632A1 (de) *	1991-10-01	1993-04-08	Bayer Ag	Substituierte imidazolyl-propensaeurederivate
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DE4132633A1 (de) *	1991-10-01	1993-04-08	Bayer Ag	Cyclisch substituierte imidazolyl-propensaeurederivate
GB9121463D0 (en) *	1991-10-10	1991-11-27	Smithkline Beecham Corp	Medicament
US5389661A (en) *	1991-12-05	1995-02-14	Warner-Lambert Company	Imidazole and 1,2,4-triazole derivatives with angiotensin II antagonist properties
US5322950A (en) *	1991-12-05	1994-06-21	Warner-Lambert Company	Imidazole with angiotensin II antagonist properties
US5308853A (en) *	1991-12-20	1994-05-03	Warner-Lambert Company	Substituted-5-methylidene hydantoins with AT1 receptor antagonist properties
US5240953A (en) *	1992-01-30	1993-08-31	Ortho Pharmaceutical Corporation	Substituted triazoles as angiotensin ii inhibitors
FR2687674B1 (fr) *	1992-02-07	1995-05-19	Roussel Uclaf	Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
DE4206042A1 (de) *	1992-02-27	1993-09-02	Bayer Ag	Sulfonylbenzyl-substituierte imidazopyridine
DE4206041A1 (de) *	1992-02-27	1993-09-02	Bayer Ag	Sulfonylbenzyl-substituierte imidazolylpropensaeurederivate
DE4206045A1 (de) *	1992-02-27	1993-09-02	Bayer Ag	Sulfonylbenzyl substituierte pyridone
DE4206043A1 (de) *	1992-02-27	1993-09-02	Bayer Ag	Sulfonylbenzyl-substituierte imidazole
US5364869A (en) *	1992-03-09	1994-11-15	Abbott Laboratories	Heterocycle-substituted benzyaminopyridine angiotensin II receptor antagonists
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FR2689508B1 (fr) *	1992-04-01	1994-06-17	Fournier Ind & Sante	Derives de l'imidazole, leur procede de preparation et leur application en therapeutique.
DE4212796A1 (de) *	1992-04-16	1993-10-21	Bayer Ag	Propenoyl-imidazolderivate
DE4215588A1 (de) *	1992-05-12	1993-11-18	Bayer Ag	Biphenylmethyl-substituierte Pyridone
DE4215587A1 (de) *	1992-05-12	1993-11-18	Bayer Ag	Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone
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JP3004728B2 (ja) *	1994-04-29	2000-01-31	ファイザーインク．	神経伝達物質放出増強薬としての新規な非環式および環式アミド類
JPH10505085A (ja) *	1994-09-02	1998-05-19	スミスクライン・ビーチャム・コーポレイション	エンドセリン受容体拮抗薬
US20030004202A1 (en)	1997-04-28	2003-01-02	Smithkline Beecham Corporation	Endothelin receptor antagonists
US6071931A (en) *	1995-10-06	2000-06-06	Novartis Ag	AT1 -receptor antagonists for preventing and treating postischemic renal failure and for protecting ischemic kidneys
EP0868180A4 (en) *	1995-12-21	1999-08-04	Smithkline Beecham Corp	ENDOTHELINM RECEPTOR ANTOGONISTS
ES2189940T3 (es)	1996-02-29	2003-07-16	Novartis Ag	Antagonista de receptor at1 para la estimulacion de la apoptosis.
AR011126A1 (es)	1997-02-14	2000-08-02	Smithkline Beecham Corp	Procedimiento para preparar eprosartano y compuestos intermediarios.
JP2002520385A (ja)	1998-07-18	2002-07-09	バイエルアクチェンゲゼルシャフト	イミドアミド誘導体
US6465502B1 (en)	1998-12-23	2002-10-15	Novartis Ag	Additional therapeutic use
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AR033390A1 (es)	2000-08-22	2003-12-17	Novartis Ag	Una composicion farmaceutica que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina, el uso de dicha composicion para la fabricacion de un medicamento y un kit de partes
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1990
- 1990-06-07 ES ES90306204T patent/ES2142789T3/es not_active Expired - Lifetime
- 1990-06-07 ES ES99115614T patent/ES2207091T3/es not_active Expired - Lifetime
- 1990-06-07 DE DE69033469T patent/DE69033469T2/de not_active Expired - Lifetime
- 1990-06-07 DE DE69034103T patent/DE69034103T2/de not_active Expired - Lifetime
- 1990-06-07 SG SG1996002914A patent/SG52330A1/en unknown
- 1990-06-07 AT AT99115614T patent/ATE250587T1/de not_active IP Right Cessation
- 1990-06-07 DE DE2000175018 patent/DE10075018I2/de active Active
- 1990-06-07 EP EP99115614A patent/EP0955294B1/en not_active Expired - Lifetime
- 1990-06-07 CA CA002018438A patent/CA2018438C/en not_active Expired - Lifetime
- 1990-06-07 DK DK99115614T patent/DK0955294T3/da active
- 1990-06-07 EP EP90306204A patent/EP0403159B1/en not_active Expired - Lifetime
- 1990-06-07 AT AT90306204T patent/ATE190051T1/de active
- 1990-06-07 DK DK90306204T patent/DK0403159T3/da active
- 1990-06-08 NZ NZ233997A patent/NZ233997A/en unknown
- 1990-06-08 ZW ZW94/90A patent/ZW9490A1/xx unknown
- 1990-06-11 PH PH40649A patent/PH27592A/en unknown
- 1990-06-11 IL IL9469890A patent/IL94698A/en unknown
- 1990-06-12 PL PL90285591A patent/PL165609B1/pl unknown
- 1990-06-12 PT PT94377A patent/PT94377B/pt not_active IP Right Cessation
- 1990-06-12 PL PL90301863A patent/PL166669B1/pl unknown
- 1990-06-12 PL PL90301864A patent/PL166722B1/pl unknown
- 1990-06-13 IE IE214090A patent/IE902140A1/en not_active IP Right Cessation
- 1990-06-13 FI FI902970A patent/FI102610B/fi active IP Right Grant
- 1990-06-13 IE IE20000297A patent/IE20000297A1/en unknown
- 1990-06-13 NO NO902632A patent/NO175977C/no not_active IP Right Cessation
- 1990-06-13 MA MA22145A patent/MA21896A1/fr unknown
- 1990-06-14 KR KR1019900008739A patent/KR0165837B1/ko not_active Expired - Lifetime
- 1990-06-14 JP JP2156627A patent/JPH0768223B2/ja not_active Expired - Lifetime
- 1990-06-14 HU HU903847A patent/HU208537B/hu unknown
- 1990-06-14 CN CN90104438A patent/CN1027504C/zh not_active Expired - Lifetime
1993
- 1993-03-16 CN CN93103111A patent/CN1048159C/zh not_active Expired - Lifetime
2000
- 2000-04-05 LU LU90562C patent/LU90562I2/xx unknown
- 2000-05-16 NL NL300006C patent/NL300006I2/nl unknown
- 2000-05-19 GR GR20000401140T patent/GR3033452T3/el not_active IP Right Cessation
2001
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Also Published As

Publication number	Publication date
ZW9490A1 (en)	1990-10-31
FI102610B1 (fi)	1999-01-15
ES2207091T3 (es)	2004-05-16
EP0403159A3 (en)	1991-12-27
IL94698A (en)	1994-07-31
DK0955294T3 (da)	2004-02-02
HU208537B (en)	1993-11-29
NL300006I1 (nl)	2000-07-03
NO175977C (no)	1995-01-11
EP0403159B1 (en)	2000-03-01
PL166669B1 (pl)	1995-06-30
EP0403159A2 (en)	1990-12-19
KR0165837B1 (ko)	1999-02-18
PL165609B1 (pl)	1995-01-31
AU5690190A (en)	1991-01-10
CN1079649A (zh)	1993-12-22
ATE250587T1 (de)	2003-10-15
ES2142789T3 (es)	2000-05-01
NL300006I2 (nl)	2000-10-02
CN1048038A (zh)	1990-12-26
NO902632L (no)	1990-12-17
PT94377B (pt)	1997-02-28
SG52330A1 (en)	1998-09-28
AU633322B2 (en)	1993-01-28
FI902970A0 (fi)	1990-06-13
IE20000297A1 (en)	2000-12-13
FI102610B (fi)	1999-01-15
HUT55011A (en)	1991-04-29
NZ233997A (en)	1991-04-26
EP0955294A3 (en)	2000-04-19
LU90562I2 (fr)	2000-06-05
DE10075018I1 (de)	2000-09-21
DE69034103D1 (de)	2003-10-30
DE69033469T2 (de)	2000-09-07
EP0955294B1 (en)	2003-09-24
JPH03115278A (ja)	1991-05-16
IE902140L (en)	1990-12-14
CN1027504C (zh)	1995-01-25
DE69034103T2 (de)	2004-07-15
EP0955294A2 (en)	1999-11-10
JPH0768223B2 (ja)	1995-07-26
DE69033469D1 (de)	2000-04-06
NO902632D0 (no)	1990-06-13
HK1025315A1 (en)	2000-11-10
PL285591A1 (en)	1991-03-25
PH27592A (en)	1993-08-31
DK0403159T3 (da)	2000-08-14
GR3033452T3 (en)	2000-09-29
IE902140A1 (en)	1991-01-02
HU903847D0 (en)	1990-11-28
CN1048159C (zh)	2000-01-12
HK1012384A1 (en)	1999-07-30
CY2232B1 (en)	2003-04-18
KR910000658A (ko)	1991-01-29
CA2018438C (en)	2000-08-08
DE10075018I2 (de)	2001-08-09
MA21896A1 (fr)	1991-04-01
ATE190051T1 (de)	2000-03-15
NO175977B (no)	1994-10-03
PL166722B1 (pl)	1995-06-30
IL94698A0 (en)	1991-04-15
CA2018438A1 (en)	1990-12-14

Publication	Publication Date	Title
PT94377A (pt)	1991-03-20	Processo de preparacao de acidos imidazolilalcenoicos e de composicoes farmaceuticas que os contem
ES2062403T3 (es)	1994-12-16	5-((tetrazolil)-alquenil)-imidazoles sustituidos.
PL287631A1 (en)	1991-12-16	Method of obtaining novel substituted derivatives of n-/imidazolil/-alkyl-alamine
PT90717A (pt)	1989-12-29	Processo de preparacao de 3,4,5,6-tetra-hidrofuro {4,3,2,ef}{3}benzazepinas substituidas e de composicoes farmaceuticas que as contem

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1997-02-28

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Effective date: 19961121

2011-11-29

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