PT932678E - Familia de genes que codificam peptidos relacionados com apoptose, peptidos por eles codificados e metodos para sua utilizacao - Google Patents
Familia de genes que codificam peptidos relacionados com apoptose, peptidos por eles codificados e metodos para sua utilizacaoInfo
- Publication number
- PT932678E PT932678E PT97945277T PT97945277T PT932678E PT 932678 E PT932678 E PT 932678E PT 97945277 T PT97945277 T PT 97945277T PT 97945277 T PT97945277 T PT 97945277T PT 932678 E PT932678 E PT 932678E
- Authority
- PT
- Portugal
- Prior art keywords
- sarp
- methods
- genes
- peptide
- family
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2660396P | 1996-09-24 | 1996-09-24 | |
| US2836396P | 1996-10-11 | 1996-10-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT932678E true PT932678E (pt) | 2006-07-31 |
Family
ID=26701439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97945277T PT932678E (pt) | 1996-09-24 | 1997-09-24 | Familia de genes que codificam peptidos relacionados com apoptose, peptidos por eles codificados e metodos para sua utilizacao |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6433155B1 (pt) |
| EP (1) | EP0932678B2 (pt) |
| JP (2) | JP4299886B2 (pt) |
| AT (1) | ATE318915T1 (pt) |
| AU (1) | AU737323B2 (pt) |
| CA (1) | CA2266325C (pt) |
| DE (1) | DE69735375T3 (pt) |
| DK (1) | DK0932678T4 (pt) |
| ES (1) | ES2263181T5 (pt) |
| PT (1) | PT932678E (pt) |
| WO (1) | WO1998013493A2 (pt) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070299005A1 (en) * | 1996-09-24 | 2007-12-27 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
| EP0954580B1 (en) * | 1997-02-06 | 2003-12-17 | Genetics Institute, LLC | Human sdf-5 protein and compositions |
| CA2224473A1 (en) * | 1997-05-21 | 1998-11-21 | Smithkline Beecham Corporation | A novel human gene similar to a secreted murine protein sdf5 |
| EP0879885A1 (en) * | 1997-05-23 | 1998-11-25 | Smithkline Beecham Corporation | A novel human gene similar to a secreted murine protein sFRP-1 |
| AU7704498A (en) * | 1997-05-29 | 1998-12-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Human frp and fragments thereof including methods for using them |
| US20030203446A1 (en) * | 1998-10-07 | 2003-10-30 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| JP2002538769A (ja) * | 1998-10-30 | 2002-11-19 | ユニバーシティ オブ ネブラスカ−リンカーン | アポトーシス遺伝子の異種間移入及びそれにより開発されたトランスジェニック植物 |
| GB9921009D0 (en) * | 1999-09-07 | 1999-11-10 | Neuropa Ltd | Essential genes and assays relating thereto |
| US20080166356A9 (en) * | 1999-09-13 | 2008-07-10 | Peter Bodine | Pharmaceutical compositions and methods of using secreted frizzled related protein |
| US6600018B1 (en) * | 2000-04-10 | 2003-07-29 | The United States Of America As Represented By The Department Of Health And Human Services | Secreted frizzled related protein, sFRP, fragments and methods of use thereof |
| AU2002226366B2 (en) * | 2000-12-06 | 2007-03-22 | Laboratoires Serono Sa | Use of SARP-1 for the treatment and/or prevention of scleroderma |
| JP4029041B2 (ja) | 2001-01-10 | 2008-01-09 | アメリカ合衆国 | sFRPおよびsFRPと相互作用するペプチドモチーフならびにそれらの使用法 |
| EP1222933A1 (en) * | 2001-01-15 | 2002-07-17 | Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum | Generation and/or reduction of new lung tissue in an affected lung, by modulation of the Wnt-pathway |
| AU2002308557A1 (en) | 2001-05-01 | 2002-11-11 | The Regents Of The University Of California | Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas |
| US20030044409A1 (en) * | 2001-05-01 | 2003-03-06 | Carson Dennis A. | Immunologic compositions and methods for studying and treating cancers expressing frizzled antigens |
| AU2003259285A1 (en) * | 2002-07-29 | 2004-02-16 | Hmgene, Inc. | Methods of identifying adipocyte specific genes, the genes identified, and their uses |
| US20050054599A1 (en) * | 2003-05-02 | 2005-03-10 | Coles John G. | Biosynthetic platform for cardioprotective stress response in human fetal heart tissue |
| KR20060129263A (ko) * | 2003-12-16 | 2006-12-15 | 아벤티스 파마슈티칼스 인크. | 분비된 신경 아폽토시스 억제 단백질 |
| BRPI0513692B8 (pt) | 2004-07-23 | 2021-07-27 | Pacific Edge Biotechnology Ltd | processos para detecção de câncer de bexiga em um indivíduo |
| US7638128B2 (en) * | 2005-08-19 | 2009-12-29 | The Brigham And Women's Hospital, Inc. | Method of enhancing cardiac tissue repair by administering a SFRP polypeptide |
| US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
| PT2500360E (pt) * | 2005-10-31 | 2015-10-15 | Oncomed Pharm Inc | Composições e métodos para diagnóstico e tratamento do cancro |
| NZ545243A (en) | 2006-02-10 | 2009-07-31 | Pacific Edge Biotechnology Ltd | Urine gene expression ratios for detection of cancer |
| PE20120807A1 (es) * | 2006-09-08 | 2012-07-26 | Genentech Inc | Antagonistas del gen wnt y su uso en el diagnostico y tratamiento de trastornos mediados por el wnt |
| MX2011003183A (es) | 2008-09-26 | 2011-04-21 | Oncomed Pharm Inc | Agentes que se unen a receptor encrespado y usos de los mismos. |
| TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Wnt拮抗劑及治療和篩選方法 |
| KR20130043102A (ko) | 2010-04-01 | 2013-04-29 | 온코메드 파마슈티칼스, 인크. | 프리즐드-결합 작용제 및 그의 용도 |
| CA2807552A1 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| EP3431485B2 (en) | 2010-10-01 | 2024-09-04 | ModernaTX, Inc. | Engineered nucleic acids and methods of use thereof |
| WO2012135805A2 (en) | 2011-03-31 | 2012-10-04 | modeRNA Therapeutics | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| EP2763701B1 (en) | 2011-10-03 | 2018-12-19 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
| KR20140102759A (ko) | 2011-12-16 | 2014-08-22 | 모더나 세라퓨틱스, 인코포레이티드 | 변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물 |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| DE18200782T1 (de) | 2012-04-02 | 2021-10-21 | Modernatx, Inc. | Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen |
| HK1212216A1 (en) | 2012-10-23 | 2016-06-10 | Oncomed Pharmaceuticals, Inc. | Methods of treating neuroendocrine tumors using wnt pathway-binding agents |
| CA2892529C (en) | 2012-11-26 | 2023-04-25 | Moderna Therapeutics, Inc. | Terminally modified rna |
| HK1211887A1 (en) | 2013-02-04 | 2016-06-03 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a wnt pathway inhibitor |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| EA201690675A1 (ru) | 2013-10-03 | 2016-08-31 | Модерна Терапьютикс, Инк. | Полинуклеотиды, кодирующие рецептор липопротеинов низкой плотности |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| WO1993004169A1 (en) | 1991-08-20 | 1993-03-04 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
| US5639856A (en) * | 1993-09-13 | 1997-06-17 | The Regents Of The University Of California | Semaphorin gene family |
| US5663070A (en) | 1993-11-15 | 1997-09-02 | Lxr Biotechnology Inc. | Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM |
| US5759548A (en) | 1993-11-30 | 1998-06-02 | Lxr Biotechnology Inc. | Compositions which inhibit apoptosis, methods of purifying the compositions and uses thereof |
| US5672686A (en) | 1994-08-09 | 1997-09-30 | Immunogen, Inc. | Bcl-Y - specific antibodies |
-
1997
- 1997-09-24 PT PT97945277T patent/PT932678E/pt unknown
- 1997-09-24 JP JP51587798A patent/JP4299886B2/ja not_active Expired - Lifetime
- 1997-09-24 CA CA2266325A patent/CA2266325C/en not_active Expired - Lifetime
- 1997-09-24 US US08/937,067 patent/US6433155B1/en not_active Expired - Lifetime
- 1997-09-24 WO PCT/US1997/017154 patent/WO1998013493A2/en not_active Ceased
- 1997-09-24 AU AU46513/97A patent/AU737323B2/en not_active Expired
- 1997-09-24 DK DK97945277.8T patent/DK0932678T4/da active
- 1997-09-24 AT AT97945277T patent/ATE318915T1/de active
- 1997-09-24 DE DE69735375T patent/DE69735375T3/de not_active Expired - Lifetime
- 1997-09-24 EP EP97945277A patent/EP0932678B2/en not_active Expired - Lifetime
- 1997-09-24 ES ES97945277T patent/ES2263181T5/es not_active Expired - Lifetime
-
2002
- 2002-05-14 US US10/146,474 patent/US7045596B2/en not_active Expired - Lifetime
- 2002-11-20 US US10/301,764 patent/US7045604B2/en not_active Expired - Lifetime
-
2008
- 2008-07-28 JP JP2008194206A patent/JP2009050257A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009050257A (ja) | 2009-03-12 |
| DK0932678T3 (da) | 2006-05-22 |
| DE69735375D1 (de) | 2006-04-27 |
| ES2263181T5 (es) | 2011-04-07 |
| DE69735375T2 (de) | 2006-11-30 |
| EP0932678B2 (en) | 2010-03-10 |
| WO1998013493A3 (en) | 1998-06-04 |
| EP0932678B1 (en) | 2006-03-01 |
| CA2266325A1 (en) | 1998-04-02 |
| US7045604B2 (en) | 2006-05-16 |
| WO1998013493A2 (en) | 1998-04-02 |
| CA2266325C (en) | 2012-07-17 |
| ATE318915T1 (de) | 2006-03-15 |
| AU4651397A (en) | 1998-04-17 |
| US6433155B1 (en) | 2002-08-13 |
| JP4299886B2 (ja) | 2009-07-22 |
| ES2263181T3 (es) | 2006-12-01 |
| US7045596B2 (en) | 2006-05-16 |
| DE69735375T3 (de) | 2010-09-02 |
| DK0932678T4 (da) | 2010-07-12 |
| US20040039184A1 (en) | 2004-02-26 |
| US20030023061A1 (en) | 2003-01-30 |
| JP2002516564A (ja) | 2002-06-04 |
| AU737323B2 (en) | 2001-08-16 |
| EP0932678A2 (en) | 1999-08-04 |
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