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PT930933E - Metodo para a libertacao de um principio activo contido numa emulsao multipla - Google Patents

Metodo para a libertacao de um principio activo contido numa emulsao multipla

Info

Publication number
PT930933E
PT930933E PT98941547T PT98941547T PT930933E PT 930933 E PT930933 E PT 930933E PT 98941547 T PT98941547 T PT 98941547T PT 98941547 T PT98941547 T PT 98941547T PT 930933 E PT930933 E PT 930933E
Authority
PT
Portugal
Prior art keywords
emulsion
aqueous phase
liberation
active principle
active ingredient
Prior art date
Application number
PT98941547T
Other languages
English (en)
Inventor
Jerome Bibette
Marie-Francoise Ficheux
Fernando Leal Calderon
Lida Bonnakdar
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of PT930933E publication Critical patent/PT930933E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02—Separation of non-miscible liquids
    • B01D17/04—Breaking emulsions
    • B01D17/047—Breaking emulsions with separation aids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/4105—Methods of emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4141—High internal phase ratio [HIPR] emulsions, e.g. having high percentage of internal phase, e.g. higher than 60-90 % of water in oil [W/O]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Colloid Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PT98941547T 1997-08-07 1998-08-05 Metodo para a libertacao de um principio activo contido numa emulsao multipla PT930933E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9710154A FR2767064B1 (fr) 1997-08-07 1997-08-07 Procede de liberation d'un principe actif contenu dans une emulsion multiple

Publications (1)

Publication Number Publication Date
PT930933E true PT930933E (pt) 2003-07-31

Family

ID=9510141

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98941547T PT930933E (pt) 1997-08-07 1998-08-05 Metodo para a libertacao de um principio activo contido numa emulsao multipla

Country Status (11)

Country Link
US (1) US6627603B1 (pt)
EP (1) EP0930933B1 (pt)
JP (1) JP3725559B2 (pt)
AT (1) ATE237395T1 (pt)
AU (1) AU729461B2 (pt)
CA (1) CA2267083C (pt)
DE (1) DE69813498T2 (pt)
ES (1) ES2200364T3 (pt)
FR (1) FR2767064B1 (pt)
PT (1) PT930933E (pt)
WO (1) WO1999007463A1 (pt)

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FR2798601B1 (fr) * 1999-09-20 2001-12-21 Centre Nat Rech Scient Emulsion double polydisperse, emulsion double monodisperse correspondante et procede de preparation de l'emulsion monodisperse
FR2808703B1 (fr) * 2000-05-09 2002-08-02 Centre Nat Rech Scient Procede de preparation d'une emulsion double monodisperse
DE10211313A1 (de) * 2002-03-14 2003-10-02 Wacker Chemie Gmbh Mehrfachemulsionen
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
FR2860717B1 (fr) * 2003-10-13 2006-02-03 Ethypharm Sa Compositions de particules lipidiques solides monodisperses
FR2862235B1 (fr) * 2003-11-13 2007-12-28 Rhodia Chimie Sa Emulsion pour vehiculer une matiere active hydrophobe vers un substrat en milieu aqueux
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
AU2006257727B2 (en) * 2005-06-17 2010-09-09 Encap Hive Pty Ltd Particles comprising a releasable dopant therein
CN101237860B (zh) * 2005-06-17 2011-11-09 澳大利亚核科学技术组织 其中具有疏水材料的颗粒
JP5388005B2 (ja) * 2005-06-17 2014-01-15 オーストラリアン ニュークリア サイエンス アンド テクノロジー オーガニゼーション 放出可能なドーパントをその中に含有する粒子
AU2006257726B2 (en) * 2005-06-17 2010-09-09 Australian Nuclear Science And Technology Organisation Particles having hydrophobic material therein
AU2006335290A1 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
EP4190448A3 (en) 2006-05-11 2023-09-20 Bio-Rad Laboratories, Inc. Microfluidic devices
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP3536396B1 (en) 2006-08-07 2022-03-30 The President and Fellows of Harvard College Fluorocarbon emulsion stabilizing surfactants
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
EP4047367A1 (en) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Method for detecting target analytes with droplet libraries
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
EP3415235B1 (en) 2009-03-23 2025-11-12 Bio-Rad Laboratories, Inc. Manipulation of microfluidic droplets
US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
EP2517025B1 (en) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Methods for reducing the exchange of molecules between droplets
WO2011100604A2 (en) 2010-02-12 2011-08-18 Raindance Technologies, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
GB2482911A (en) 2010-08-20 2012-02-22 Sphere Fluidics Ltd Microdroplet emulsion system
WO2012045012A2 (en) 2010-09-30 2012-04-05 Raindance Technologies, Inc. Sandwich assays in droplets
EP3859011A1 (en) 2011-02-11 2021-08-04 Bio-Rad Laboratories, Inc. Methods for forming mixed droplets
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
WO2012140155A1 (en) * 2011-04-14 2012-10-18 Novo Nordisk A/S Fatty acid acylated amino acids for oral peptide delivery
DE202012013668U1 (de) 2011-06-02 2019-04-18 Raindance Technologies, Inc. Enzymquantifizierung
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
WO2013165579A1 (en) 2012-04-30 2013-11-07 Life Technologies Corporation Polymer-based emulsion breaking methods
WO2014060447A1 (en) * 2012-10-17 2014-04-24 Novo Nordisk A/S Fatty acid acylated d-amino acids for oral peptide delivery
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
EP3662756A1 (en) * 2018-12-07 2020-06-10 General Mills, Inc. Multiple emulsions, method of making them and applications in food, cosmetics and pharmaceuticals
CN110638666B (zh) * 2019-11-13 2022-06-24 瑞希(重庆)生物科技有限公司 一种w/o/w型多重乳液及其制备方法

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DE69229779T2 (de) * 1991-04-19 1999-12-23 Lds Technologies, Inc. Konvertierbare mikroemulsionsverbindungen
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
US5589177A (en) * 1994-12-06 1996-12-31 Helene Curtis, Inc. Rinse-off water-in-oil-in-water compositions
DE19509301A1 (de) * 1995-03-15 1996-09-19 Henkel Kgaa Multiple W/O/W-Emulsionen

Also Published As

Publication number Publication date
FR2767064A1 (fr) 1999-02-12
US6627603B1 (en) 2003-09-30
JP3725559B2 (ja) 2005-12-14
FR2767064B1 (fr) 1999-11-12
EP0930933B1 (fr) 2003-04-16
ATE237395T1 (de) 2003-05-15
CA2267083C (fr) 2004-01-27
DE69813498T2 (de) 2003-12-24
ES2200364T3 (es) 2004-03-01
EP0930933A1 (fr) 1999-07-28
CA2267083A1 (fr) 1999-02-18
DE69813498D1 (de) 2003-05-22
AU729461B2 (en) 2001-02-01
WO1999007463A1 (fr) 1999-02-18
AU8988798A (en) 1999-03-01
JP2000503685A (ja) 2000-03-28

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