[go: up one dir, main page]

PT90341A - Processo para a preparacao de um sistema de fornecimento oral de distribuicao continua osmotica, contendo metoprolol como agente activo farmaceuticamente aceitavel, tendo melhores propriedades de adesao da membrana do nucleo - Google Patents

Processo para a preparacao de um sistema de fornecimento oral de distribuicao continua osmotica, contendo metoprolol como agente activo farmaceuticamente aceitavel, tendo melhores propriedades de adesao da membrana do nucleo

Info

Publication number
PT90341A
PT90341A PT90341A PT9034189A PT90341A PT 90341 A PT90341 A PT 90341A PT 90341 A PT90341 A PT 90341A PT 9034189 A PT9034189 A PT 9034189A PT 90341 A PT90341 A PT 90341A
Authority
PT
Portugal
Prior art keywords
adhesion
preparation
pharmaceutically acceptable
active agent
supply system
Prior art date
Application number
PT90341A
Other languages
English (en)
Other versions
PT90341B (pt
Inventor
Shailesh B Shah
Arun Dattatreya Koparkar
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT90341A publication Critical patent/PT90341A/pt
Publication of PT90341B publication Critical patent/PT90341B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Confectionery (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • External Artificial Organs (AREA)
PT90341A 1988-04-25 1989-04-21 Processo para a preparacao de um sistema de fornecimento oral de distribuicao continua osmotica, contendo metoprolol como agente activo farmaceuticamente aceitavel, tendo melhores propriedades de adesao da membrana do nucleo PT90341B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/185,564 US4892739A (en) 1988-04-25 1988-04-25 Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties

Publications (2)

Publication Number Publication Date
PT90341A true PT90341A (pt) 1989-11-10
PT90341B PT90341B (pt) 1994-08-31

Family

ID=22681522

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90341A PT90341B (pt) 1988-04-25 1989-04-21 Processo para a preparacao de um sistema de fornecimento oral de distribuicao continua osmotica, contendo metoprolol como agente activo farmaceuticamente aceitavel, tendo melhores propriedades de adesao da membrana do nucleo

Country Status (22)

Country Link
US (1) US4892739A (pt)
EP (1) EP0339506B1 (pt)
JP (1) JP2750150B2 (pt)
KR (1) KR0125935B1 (pt)
AT (1) ATE75939T1 (pt)
AU (1) AU618083B2 (pt)
CA (1) CA1334382C (pt)
DD (1) DD288093A5 (pt)
DE (1) DE58901373D1 (pt)
DK (1) DK175232B1 (pt)
ES (1) ES2031302T3 (pt)
FI (1) FI90203C (pt)
GR (1) GR3005399T3 (pt)
HU (1) HU201469B (pt)
IE (1) IE61223B1 (pt)
IL (1) IL90019A (pt)
MX (1) MX15754A (pt)
NO (1) NO175186C (pt)
NZ (1) NZ228845A (pt)
PH (1) PH27150A (pt)
PT (1) PT90341B (pt)
ZA (1) ZA892998B (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023076A (en) * 1987-02-27 1991-06-11 Alza Corporation Lamina comprising carboxyvinyl polymer
US5156850A (en) * 1990-08-31 1992-10-20 Alza Corporation Dosage form for time-varying patterns of drug delivery
US5232705A (en) * 1990-08-31 1993-08-03 Alza Corporation Dosage form for time-varying patterns of drug delivery
US6764697B1 (en) 1991-06-27 2004-07-20 Alza Corporation System for delaying drug delivery up to seven hours
ATE195252T1 (de) * 1993-04-23 2000-08-15 Novartis Erfind Verwalt Gmbh Wirkstoffabgabevorrichtung mit gesteuerter freigabe
US8524277B2 (en) * 1998-03-06 2013-09-03 Alza Corporation Extended release dosage form
US6099859A (en) * 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
US6099862A (en) 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
SE0003125D0 (sv) * 2000-09-05 2000-09-05 Astrazeneca Ab Modified polymers
US6790459B1 (en) 2000-11-03 2004-09-14 Andrx Labs, Llc Methods for treating diabetes via administration of controlled release metformin
JP2004531463A (ja) 2000-11-03 2004-10-14 アンドルクス ラブス，エルエルシー 徐放メトホルミン組成物
US20060034922A1 (en) * 2000-11-03 2006-02-16 Andrx Labs, Llc Controlled release metformin compositions
US6866866B1 (en) * 2000-11-03 2005-03-15 Andrx Labs, Llc Controlled release metformin compositions
US6610326B2 (en) * 2001-02-16 2003-08-26 Andrx Corporation Divalproex sodium tablets
WO2003011255A1 (en) * 2001-07-04 2003-02-13 Sun Pharmaceutical Industries Limited Gastric retention controlled drug delivery system
GB2384986B (en) * 2002-02-12 2004-01-07 Reckitt Benckiser Healthcare Compositions for the treatment of disorders of the upper gastrointestinal tract
WO2003099214A2 (en) * 2002-05-23 2003-12-04 Andrx Corporation Biguanide formulations
US20050048119A1 (en) * 2002-09-20 2005-03-03 Avinash Nangia Controlled release composition with semi-permeable membrane and poloxamer flux enhancer
WO2004026241A2 (en) 2002-09-20 2004-04-01 Andrx Labs Llc Multistage formulation containing a biguanide and thiazolidindione derivatives
US20050051922A1 (en) * 2002-09-20 2005-03-10 Avinash Nangia Pharmaceutical composition with sodium lauryl sulfate as an extra-granular absorption/compression enhancer and the process to make the same
AU2003903507A0 (en) * 2003-07-08 2003-07-24 U. S. Filter Wastewater Group, Inc. Membrane post-treatment
US7314640B2 (en) * 2003-07-11 2008-01-01 Mongkol Sriwongjanya Formulation and process for drug loaded cores
US20050196448A1 (en) * 2004-03-05 2005-09-08 Hai Yong Huang Polymeric compositions and dosage forms comprising the same
US20050196446A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196447A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
MXPA06010003A (es) * 2004-03-05 2007-03-21 Johnson & Johnson Composiciones polimericas y formas de dosificacion que comprenden las mismas.
US20050196442A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050287185A1 (en) * 2004-06-23 2005-12-29 David Wong Extended release oxybutynin formulation
ATE523240T1 (de) * 2004-07-05 2011-09-15 Siemens Water Tech Corp Hydrophile membranen
IL166114A0 (en) * 2005-01-03 2006-01-15 Calcident Active Ltd Long-acting controlled-release pharmaceutical preparation for use in the oral cavity
CN102670539A (zh) * 2011-03-14 2012-09-19 北京天衡药物研究院 琥珀酸美托洛尔渗透泵控释片
CN102670555A (zh) * 2011-03-14 2012-09-19 北京天衡药物研究院 富马酸美托洛尔渗透泵控释片
EP2895257A1 (en) 2012-09-14 2015-07-22 Evoqua Water Technologies LLC A polymer blend for membranes
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
AU2016294153B2 (en) 2015-07-14 2022-01-20 Evoqua Water Technologies Llc Aeration device for filtration system
CA3107174A1 (en) * 2018-07-24 2020-01-30 Bayer Aktiengesellschaft Pharmaceutical dosage form which can be administered orally and has modified release
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
US20230355939A1 (en) * 2020-09-15 2023-11-09 Synagile Corporation Devices and methods for continuous extrusion of a drug into the mouth

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4256108A (en) * 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4439195A (en) * 1980-10-14 1984-03-27 Alza Corporation Theophylline therapy
US4326525A (en) * 1980-10-14 1982-04-27 Alza Corporation Osmotic device that improves delivery properties of agent in situ
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4455143A (en) * 1982-03-22 1984-06-19 Alza Corporation Osmotic device for dispensing two different medications
US4681583A (en) * 1982-12-20 1987-07-21 Alza Corporation System for dispersing drug in biological environment
US4578075A (en) * 1982-12-20 1986-03-25 Alza Corporation Delivery system housing a plurality of delivery devices
US4576604A (en) * 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
SE457505B (sv) * 1984-01-10 1989-01-09 Lejus Medical Ab Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
WO1985003436A1 (en) * 1984-02-10 1985-08-15 A/S Alfred Benzon Diffusion coated multiple-units dosage form
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
US4609374A (en) * 1985-04-22 1986-09-02 Alza Corporation Osmotic device comprising means for governing initial time of agent release therefrom
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
EP0271438B1 (de) * 1986-11-14 1992-04-29 Ciba-Geigy Ag Orales osmotisches System für Metoprolol mit verbesserten Formulierungseigenschaften

Also Published As

Publication number Publication date
IL90019A0 (en) 1989-12-15
KR900015734A (ko) 1990-11-10
ES2031302T3 (es) 1992-12-01
FI90203B (fi) 1993-09-30
IE61223B1 (en) 1994-10-19
EP0339506A1 (de) 1989-11-02
US4892739A (en) 1990-01-09
FI891921A0 (fi) 1989-04-21
DK196189A (da) 1989-10-26
JPH029815A (ja) 1990-01-12
DK175232B1 (da) 2004-07-19
GR3005399T3 (pt) 1993-05-24
FI90203C (fi) 1994-01-10
ATE75939T1 (de) 1992-05-15
NZ228845A (en) 1990-10-26
IE891316L (en) 1989-10-25
DE58901373D1 (de) 1992-06-17
CA1334382C (en) 1995-02-14
HU201469B (en) 1990-11-28
NO891680L (no) 1989-10-26
PT90341B (pt) 1994-08-31
AU3268789A (en) 1989-10-26
AU618083B2 (en) 1991-12-12
PH27150A (en) 1993-04-02
DK196189D0 (da) 1989-04-24
JP2750150B2 (ja) 1998-05-13
ZA892998B (en) 1989-12-27
NO891680D0 (no) 1989-04-24
NO175186C (no) 1994-09-14
DD288093A5 (de) 1991-03-21
IL90019A (en) 1994-04-12
HUT50625A (en) 1990-03-28
FI891921A7 (fi) 1989-10-26
NO175186B (pt) 1994-06-06
MX15754A (es) 1994-01-31
KR0125935B1 (ko) 1997-12-26
EP0339506B1 (de) 1992-05-13

Similar Documents

Publication Publication Date Title
PT90341A (pt) Processo para a preparacao de um sistema de fornecimento oral de distribuicao continua osmotica, contendo metoprolol como agente activo farmaceuticamente aceitavel, tendo melhores propriedades de adesao da membrana do nucleo
PT862396E (pt) Aneis intravaginais com nucleo inserivel contendo farmaco
ATE124261T1 (de) Zusammensetzung in form eines schaumes enthaltend 5-aminosalicylic säure zur intra-rektal verabreichung.
ES2194989T3 (es) Composicion adminstrada por via oral, que comprende una toxina de zonula occludens y un agente que tiene una actividad biologica, y su utilizacion.
AU1534699A (en) Osmotic dosage form comprising first and second coats
PT88945A (pt) Processo para a preparacao de formas de dosagem farmaceuticas de libertacao controlada contendo um antagonista do calcio, tal como cloridrato de diltiazem
ES2094539T3 (es) Preparacion farmaceutica y procedimiento para su preparacion.
NO974618L (no) Farmasöytiske preparater for intranasal administrasjon
FI853934L (fi) Doseringssystem som bestaor av flera enheter och har en belaeggning som tillaoter diffusion.
BRPI0415007A (pt) método para tratar, prevenir, modificar ou administrar dor, e, composição farmacêutica
SE8601791L (sv) Osmotisk anordning med sjelvforseglande passage
DE3684354D1 (de) Arzneimittel, die hohle, feine, roehrchenfoermige wirkstoffabgabesysteme enthalten.
DE3689748D1 (de) Benzimidazolderivate, Verfahren zu deren Herstellung und deren therapeutische Anwendung.
HRP20010684B1 (hr) Izravno stlaciva matrica za kontrolirano otpustanje jednostruke dnevne doze klaritromicina
BR9812553A (pt) Formulação medicamentosa com liberação de substância ativa controlada
DE3787477D1 (de) Nasal applizierbares Arzneimittel, Verfahren zu seiner Herstellung und seine Verwendung.
DE69803772D1 (de) Oral anzuwendende feste arzneizubereitungen mit modulierter wirkstoffabgabe enthaltend nicorandil und verfahren zu deren herstellung
ATE2272T1 (de) 9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2b)thiophen-4,9-imine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
ATE6856T1 (de) Cyclopeptide und pharmazeutische praeparate davon, sowie verfahren zu ihrer herstellung und deren anwendung.
ATE52090T1 (de) Pyrazinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen mit diesen.
ATE18200T1 (de) P-acylamino-phenol-derivate mit therapeutischem effekt, verfahren zu deren herstellung und zusammensetzung mit therapeutischem effekt, diese derivate als pharmakologische aktive ingredienzen enthaltend.

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940202

PC3A Transfer or assignment

Free format text: 970530 NOVARTIS AG CH

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20090421