PT90261A - Processo para a preparacao de novos derivados com a estrutura do 3-(1-fenil-2-propenil)-{2h}-cromeno - Google Patents
Processo para a preparacao de novos derivados com a estrutura do 3-(1-fenil-2-propenil)-{2h}-cromenoInfo
- Publication number
- PT90261A PT90261A PT90261A PT9026189A PT90261A PT 90261 A PT90261 A PT 90261A PT 90261 A PT90261 A PT 90261A PT 9026189 A PT9026189 A PT 9026189A PT 90261 A PT90261 A PT 90261A
- Authority
- PT
- Portugal
- Prior art keywords
- group
- aminocarbonyl
- lower alkyl
- alkyloxy
- cromene
- Prior art date
Links
- -1 1-PHENYL-2-PROPENYL Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 2
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8804870A FR2630110B1 (fr) | 1988-04-13 | 1988-04-13 | Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT90261A true PT90261A (pt) | 1989-11-10 |
| PT90261B PT90261B (pt) | 1994-07-29 |
Family
ID=9365267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT90261A PT90261B (pt) | 1988-04-13 | 1989-04-12 | Processo para a preparacao de novos derivados com a estrutura do 3-(1-fenil-2-propenil)-{2h}-cromeno |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4975455A (pt) |
| EP (1) | EP0338895B1 (pt) |
| JP (1) | JPH01305078A (pt) |
| AT (1) | ATE80881T1 (pt) |
| AU (1) | AU610379B2 (pt) |
| CA (1) | CA1326674C (pt) |
| DE (1) | DE68902946T2 (pt) |
| DK (1) | DK179289A (pt) |
| ES (1) | ES2035598T3 (pt) |
| FR (1) | FR2630110B1 (pt) |
| GR (1) | GR3006480T3 (pt) |
| IE (1) | IE64357B1 (pt) |
| NZ (1) | NZ228716A (pt) |
| OA (1) | OA09114A (pt) |
| PT (1) | PT90261B (pt) |
| ZA (1) | ZA892716B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2630111B1 (fr) * | 1988-04-13 | 1990-07-27 | Adir | Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
| US5686465A (en) * | 1988-10-31 | 1997-11-11 | Endorecherche Inc. | Sex steroid activity inhibitors |
| US5183827A (en) * | 1989-09-19 | 1993-02-02 | Allergan, Inc. | Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
| US5250547A (en) * | 1991-08-29 | 1993-10-05 | Syntex (U.S.A.) Inc. | Benzopyran derivatives |
| US6060503A (en) * | 1991-12-02 | 2000-05-09 | Endorecherche, Inc. | Benzopyran-containing compounds and method for their use |
| JPH0852659A (ja) * | 1994-08-08 | 1996-02-27 | Tousetsu Denki Kk | バイス |
| US6586460B1 (en) | 2001-04-02 | 2003-07-01 | The Board Of Regents For Oklahoma State University | Heteroarotinoids containing urea or thiourea linker |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH651034A5 (de) * | 1982-05-12 | 1985-08-30 | Hoffmann La Roche | Chroman-, thiochroman- oder 1,2,3,4-tetrahydrochinolinderivate und ihre verwendung als arzneimittel-wirkstoffe. |
| US4808597A (en) * | 1983-07-05 | 1989-02-28 | Pfizer Inc. | Method for inhibiting the degradation of cartilage |
| JPS60178815A (ja) * | 1984-02-24 | 1985-09-12 | Rikagaku Kenkyusho | 制癌剤 |
| US4826984A (en) * | 1984-04-09 | 1989-05-02 | The Board Of Regents For The Oklahoma Agricultural And Mechanical College Acting For And On Behalf Of Oklahoma State University | Heteroarotinoid compounds as anticancer agents |
| FR2630111B1 (fr) * | 1988-04-13 | 1990-07-27 | Adir | Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2642065B1 (fr) * | 1989-01-24 | 1991-05-24 | Lipha | Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant |
-
1988
- 1988-04-13 FR FR8804870A patent/FR2630110B1/fr not_active Expired - Lifetime
-
1989
- 1989-04-10 CA CA000596390A patent/CA1326674C/fr not_active Expired - Fee Related
- 1989-04-11 US US07/336,224 patent/US4975455A/en not_active Expired - Fee Related
- 1989-04-12 NZ NZ228716A patent/NZ228716A/en unknown
- 1989-04-12 AU AU32659/89A patent/AU610379B2/en not_active Ceased
- 1989-04-12 IE IE116189A patent/IE64357B1/en not_active IP Right Cessation
- 1989-04-12 PT PT90261A patent/PT90261B/pt not_active IP Right Cessation
- 1989-04-13 DE DE8989401016T patent/DE68902946T2/de not_active Expired - Fee Related
- 1989-04-13 OA OA59560A patent/OA09114A/xx unknown
- 1989-04-13 ZA ZA892716A patent/ZA892716B/xx unknown
- 1989-04-13 JP JP1094306A patent/JPH01305078A/ja active Granted
- 1989-04-13 ES ES198989401016T patent/ES2035598T3/es not_active Expired - Lifetime
- 1989-04-13 AT AT89401016T patent/ATE80881T1/de not_active IP Right Cessation
- 1989-04-13 DK DK179289A patent/DK179289A/da not_active Application Discontinuation
- 1989-04-13 EP EP89401016A patent/EP0338895B1/fr not_active Expired - Lifetime
-
1992
- 1992-12-09 GR GR920402836T patent/GR3006480T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2630110B1 (fr) | 1990-07-27 |
| FR2630110A1 (fr) | 1989-10-20 |
| DE68902946T2 (de) | 1993-04-29 |
| ATE80881T1 (de) | 1992-10-15 |
| DK179289D0 (da) | 1989-04-13 |
| OA09114A (fr) | 1991-10-31 |
| IE891161L (en) | 1989-10-13 |
| IE64357B1 (en) | 1995-07-26 |
| ES2035598T3 (es) | 1993-04-16 |
| PT90261B (pt) | 1994-07-29 |
| ZA892716B (en) | 1989-12-27 |
| DK179289A (da) | 1989-10-14 |
| EP0338895A1 (fr) | 1989-10-25 |
| AU610379B2 (en) | 1991-05-16 |
| CA1326674C (fr) | 1994-02-01 |
| JPH0585550B2 (pt) | 1993-12-07 |
| NZ228716A (en) | 1990-11-27 |
| DE68902946D1 (de) | 1992-10-29 |
| GR3006480T3 (pt) | 1993-06-21 |
| US4975455A (en) | 1990-12-04 |
| AU3265989A (en) | 1989-12-21 |
| JPH01305078A (ja) | 1989-12-08 |
| EP0338895B1 (fr) | 1992-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940105 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19970731 |