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PT90706A - Processo para a preparacao de derivados de antraciclinas dotados de actividade citostatica - Google Patents

Processo para a preparacao de derivados de antraciclinas dotados de actividade citostatica

Info

Publication number
PT90706A
PT90706A PT90706A PT9070689A PT90706A PT 90706 A PT90706 A PT 90706A PT 90706 A PT90706 A PT 90706A PT 9070689 A PT9070689 A PT 9070689A PT 90706 A PT90706 A PT 90706A
Authority
PT
Portugal
Prior art keywords
hydrogen
hydroxyl
preparation
hydroxyl group
group
Prior art date
Application number
PT90706A
Other languages
English (en)
Other versions
PT90706B (pt
Inventor
Cenek Kolar
Dieter Hoffmann
Hans Peter Kraemer
Manfred Gerken
Peter Hermentin
Ulrich Stache
Ernst Raab
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of PT90706A publication Critical patent/PT90706A/pt
Publication of PT90706B publication Critical patent/PT90706B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT90706A 1988-06-04 1989-06-01 Processo para a preparacao de derivados de antraciclinas dotados de actividade citostatica PT90706B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3819092A DE3819092A1 (de) 1988-06-04 1988-06-04 Zytostatisch wirksame anthracyclinderivate

Publications (2)

Publication Number Publication Date
PT90706A true PT90706A (pt) 1989-12-29
PT90706B PT90706B (pt) 1993-12-31

Family

ID=6355890

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90706A PT90706B (pt) 1988-06-04 1989-06-01 Processo para a preparacao de derivados de antraciclinas dotados de actividade citostatica

Country Status (12)

Country Link
US (1) US5260425A (pt)
EP (1) EP0345598B1 (pt)
JP (1) JP2838145B2 (pt)
KR (1) KR0132566B1 (pt)
AT (1) ATE169630T1 (pt)
AU (1) AU623892B2 (pt)
CA (1) CA1340021C (pt)
DE (2) DE3819092A1 (pt)
DK (1) DK270889A (pt)
ES (1) ES2120944T3 (pt)
FI (1) FI93220C (pt)
PT (1) PT90706B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3913742A1 (de) * 1989-04-26 1990-10-31 Behringwerke Ag Zytostatisch wirksame rhodomycinderivate
DE3913743A1 (de) * 1989-04-26 1990-10-31 Behringwerke Ag Zytostatisch wirksame rhodomycinderivate
DE4036155A1 (de) * 1990-11-14 1992-05-21 Behringwerke Ag Semisynthetische diastereomerenreine n-glycidyl-anthracycline, verfahren zu ihrer stereoselektiven herstellung und ihre verwendung als zytostatika
KR100741280B1 (ko) * 2003-04-30 2007-07-19 주식회사 만도 쇽 업소버의 높이 조절 가능한 상부캡
KR20190050433A (ko) 2017-11-03 2019-05-13 신영훈 신호장치와 인식장치를 이용한 고속열차 위치 검출 시스템

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5287158A (en) * 1976-01-14 1977-07-20 Microbial Chem Res Found Deoxypypromycin and antimalignant tumor agents containing it as active constituent
JPS54141759A (en) * 1978-04-24 1979-11-05 Microbial Chem Res Found Novel anthracycline derivative
CH648327A5 (de) * 1980-10-16 1985-03-15 Hoffmann La Roche Anthracycline.
JPS57176995A (en) * 1981-04-23 1982-10-30 Sanraku Inc Novel anthracyclinone glycoside and its preparation
DE3325957A1 (de) * 1983-07-19 1985-02-07 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika
US4591637A (en) * 1985-01-17 1986-05-27 Sri International Open chain-morpholino adriamycins
JPS61227588A (ja) * 1985-04-02 1986-10-09 Sanraku Inc 新規アントラサイクリン抗生物質
JPS61236792A (ja) * 1985-04-12 1986-10-22 Sanraku Inc 新規アントラサイクリン抗生物質
FR2591599B1 (fr) * 1985-12-17 1988-08-05 Hoechst Lab Nouvelles anthracyclines et medicaments les contenant
DE3641833A1 (de) * 1986-12-08 1988-06-09 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
JPS63227599A (ja) * 1987-03-14 1988-09-21 Kirin Brewery Co Ltd アンスラサイクリン化合物およびその用途
DE3716308A1 (de) * 1987-05-15 1988-11-24 Paals Packpressen Fabrik Gmbh Kanalballenpresse
DE3722699A1 (de) * 1987-07-09 1989-01-19 Behringwerke Ag Zytostatisch wirksame anthacyclin-konjugate

Also Published As

Publication number Publication date
ATE169630T1 (de) 1998-08-15
FI892685A7 (fi) 1989-12-05
DE3819092A1 (de) 1989-12-14
JPH0225497A (ja) 1990-01-26
ES2120944T3 (es) 1998-11-16
FI93220C (fi) 1995-03-10
EP0345598A3 (de) 1990-07-18
JP2838145B2 (ja) 1998-12-16
PT90706B (pt) 1993-12-31
DK270889D0 (da) 1989-06-02
DK270889A (da) 1989-12-05
US5260425A (en) 1993-11-09
FI93220B (fi) 1994-11-30
CA1340021C (en) 1998-09-01
FI892685A0 (fi) 1989-06-01
DE58909836D1 (de) 1998-09-17
KR0132566B1 (ko) 1998-04-14
AU623892B2 (en) 1992-05-28
EP0345598A2 (de) 1989-12-13
EP0345598B1 (de) 1998-08-12
KR910000777A (ko) 1991-01-30
AU3595689A (en) 1989-12-07

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19930622

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20041222