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PT88578A - Process for the manufacture of 2,6-methanopyrrolo-3-benzazocines of intermediates useful for their manufacture and of pharmaceutical compositions containing them - Google Patents

Process for the manufacture of 2,6-methanopyrrolo-3-benzazocines of intermediates useful for their manufacture and of pharmaceutical compositions containing them

Info

Publication number
PT88578A
PT88578A PT88578A PT8857888A PT88578A PT 88578 A PT88578 A PT 88578A PT 88578 A PT88578 A PT 88578A PT 8857888 A PT8857888 A PT 8857888A PT 88578 A PT88578 A PT 88578A
Authority
PT
Portugal
Prior art keywords
manufacture
methanopyrrol
benzazocines
pharmaceutical compositions
compositions containing
Prior art date
Application number
PT88578A
Other languages
English (en)
Other versions
PT88578B (pt
Inventor
Richard C Allen
David G Wettlaufer
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT88578A publication Critical patent/PT88578A/pt
Publication of PT88578B publication Critical patent/PT88578B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PT88578A 1987-09-24 1988-09-23 Processo para a preparacao de 2,6-metanopirrolo-3-benzazocinas, de intermediarios uteis para a sua preparacao e de composicoes farmaceuticas que as contem PT88578B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10171687A 1987-09-24 1987-09-24

Publications (2)

Publication Number Publication Date
PT88578A true PT88578A (pt) 1988-10-01
PT88578B PT88578B (pt) 1992-11-30

Family

ID=22286032

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88578A PT88578B (pt) 1987-09-24 1988-09-23 Processo para a preparacao de 2,6-metanopirrolo-3-benzazocinas, de intermediarios uteis para a sua preparacao e de composicoes farmaceuticas que as contem

Country Status (7)

Country Link
EP (1) EP0308913A3 (pt)
JP (1) JPH01102077A (pt)
KR (1) KR890005104A (pt)
AU (1) AU611713B2 (pt)
DK (1) DK530488A (pt)
PT (1) PT88578B (pt)
ZA (1) ZA887087B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145965A (en) * 1987-09-24 1992-09-08 Hoechst-Roussel Pharmaceuticals Incorporated 2,6-methanopyrrolo-3-benzazocines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3331849A (en) * 1963-09-11 1967-07-18 Warner Lambert Pharmaceutical Indolomorphinans and process for their production
FR3886M (pt) * 1963-12-09 1966-01-31
US4205171A (en) * 1976-01-12 1980-05-27 Sterling Drug Inc. Aminomethanobenzazocines and nitromethanobenzazocines
NL7907800A (nl) * 1979-10-23 1981-04-27 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.
CA1159459A (en) * 1980-12-11 1983-12-27 Andre A. Asselin 6,7,8,9-tetrahydro-3h-benz¬e| indolamine derivatives
AU526331B2 (en) * 1981-04-08 1983-01-06 Sterling Drug Inc. Process for preparing 2,6-methane-3-benazocines
US4510157A (en) * 1982-12-27 1985-04-09 Ayerst, Mckenna & Harrison, Inc. 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives

Also Published As

Publication number Publication date
DK530488A (da) 1989-03-25
AU2272788A (en) 1989-04-06
EP0308913A2 (en) 1989-03-29
EP0308913A3 (en) 1990-08-22
KR890005104A (ko) 1989-05-11
AU611713B2 (en) 1991-06-20
ZA887087B (en) 1989-06-28
DK530488D0 (da) 1988-09-23
JPH01102077A (ja) 1989-04-19
PT88578B (pt) 1992-11-30

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920528

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19931130