PT832082E - N-HETEROARIL-PYRIDINESULFONAMID DERIVATIVES AND THEIR USE AS ENDOTHELINE ANTAGONISTS - Google Patents

N-HETEROARIL-PYRIDINESULFONAMID DERIVATIVES AND THEIR USE AS ENDOTHELINE ANTAGONISTS

Info

Publication number: PT832082E
Authority: PT; Portugal
Prior art keywords: pyridinesulfonamid; heteroaril; derivatives; endotheline antagonists; endotheline
Prior art date: 1995-06-07

Application number

PT96919941T

Other languages

Portuguese (pt)

Inventor

Robert Hugh Bradbury

Roger James

Roger John Butlin

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-07

Filing date

1996-06-03

Publication date

2002-04-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26307176&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT832082(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-06-07 Priority claimed from GBGB9511507.7A external-priority patent/GB9511507D0/en

1995-09-27 Priority claimed from GBGB9519666.3A external-priority patent/GB9519666D0/en

1996-06-03 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2002-04-29 Publication of PT832082E publication Critical patent/PT832082E/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Hydrogenated Pyridines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

PT96919941T 1995-06-07 1996-06-03 N-HETEROARIL-PYRIDINESULFONAMID DERIVATIVES AND THEIR USE AS ENDOTHELINE ANTAGONISTS PT832082E (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9511507.7A GB9511507D0 (en)	1995-06-07	1995-06-07	Heterocyclic compounds
GBGB9519666.3A GB9519666D0 (en)	1995-09-27	1995-09-27	Heterocyclic derivatives

Publications (1)

Publication Number	Publication Date
PT832082E true PT832082E (en)	2002-04-29

Family

ID=26307176

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT96919941T PT832082E (en)	1995-06-07	1996-06-03	N-HETEROARIL-PYRIDINESULFONAMID DERIVATIVES AND THEIR USE AS ENDOTHELINE ANTAGONISTS

Country Status (31)

Country	Link
US (3)	US5866568A (en)
EP (1)	EP0832082B1 (en)
JP (1)	JP3193058B2 (en)
KR (1)	KR100451523B1 (en)
CN (1)	CN1097051C (en)
AR (1)	AR003132A1 (en)
AT (1)	ATE209200T1 (en)
AU (1)	AU715041B2 (en)
BR (1)	BR9608611A (en)
CA (1)	CA2219742C (en)
CZ (1)	CZ289387B6 (en)
DE (1)	DE69617236T2 (en)
DK (1)	DK0832082T3 (en)
EG (1)	EG25227A (en)
ES (1)	ES2168487T3 (en)
GE (1)	GEP20053470B (en)
HR (1)	HRP960272B1 (en)
HU (1)	HUP9802300A3 (en)
IL (1)	IL122464A (en)
MX (1)	MX9709521A (en)
MY (1)	MY114926A (en)
NO (1)	NO314503B1 (en)
NZ (1)	NZ308619A (en)
PL (1)	PL187897B1 (en)
PT (1)	PT832082E (en)
RU (1)	RU2172738C2 (en)
SK (1)	SK282338B6 (en)
TR (1)	TR199701502T1 (en)
TW (1)	TW340845B (en)
UA (1)	UA58494C2 (en)
WO (1)	WO1996040681A1 (en)

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US6432994B1 (en)	1997-04-28	2002-08-13	Texas Biotechnology Corporation	Sulfonamides for treatment of endothelin-mediated disorders
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US6448239B1 (en) *	1999-06-03	2002-09-10	Trustees Of Princeton University	Peroxynitrite decomposition catalysts and methods of use thereof
EE200200363A (en)	1999-12-31	2003-08-15	Texas Biotechnology Corporation	Sulphonamides and their derivatives which modulate endothelin activity
US6639082B2 (en)	2000-10-17	2003-10-28	Bristol-Myers Squibb Company	Methods for the preparation of biphenyl isoxazole sulfonamides
US7041280B2 (en) *	2001-06-29	2006-05-09	Genzyme Corporation	Aryl boronate functionalized polymers for treating obesity
US6858592B2 (en)	2001-06-29	2005-02-22	Genzyme Corporation	Aryl boronic acids for treating obesity
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1996
- 1996-03-06 UA UA98010043A patent/UA58494C2/en unknown
- 1996-06-03 AT AT96919941T patent/ATE209200T1/en active
- 1996-06-03 EP EP96919941A patent/EP0832082B1/en not_active Expired - Lifetime
- 1996-06-03 KR KR1019970708807A patent/KR100451523B1/en not_active Expired - Fee Related
- 1996-06-03 PT PT96919941T patent/PT832082E/en unknown
- 1996-06-03 NZ NZ308619A patent/NZ308619A/en not_active IP Right Cessation
- 1996-06-03 RU RU98100054/04A patent/RU2172738C2/en not_active IP Right Cessation
- 1996-06-03 CZ CZ19973887A patent/CZ289387B6/en not_active IP Right Cessation
- 1996-06-03 AU AU58403/96A patent/AU715041B2/en not_active Ceased
- 1996-06-03 WO PCT/GB1996/001295 patent/WO1996040681A1/en not_active Ceased
- 1996-06-03 DK DK96919941T patent/DK0832082T3/en active
- 1996-06-03 HU HU9802300A patent/HUP9802300A3/en unknown
- 1996-06-03 BR BR9608611A patent/BR9608611A/en not_active IP Right Cessation
- 1996-06-03 JP JP50020997A patent/JP3193058B2/en not_active Expired - Fee Related
- 1996-06-03 ES ES96919941T patent/ES2168487T3/en not_active Expired - Lifetime
- 1996-06-03 MX MX9709521A patent/MX9709521A/en unknown
- 1996-06-03 SK SK1680-97A patent/SK282338B6/en not_active IP Right Cessation
- 1996-06-03 PL PL96324660A patent/PL187897B1/en not_active IP Right Cessation
- 1996-06-03 CA CA002219742A patent/CA2219742C/en not_active Expired - Fee Related
- 1996-06-03 IL IL12246496A patent/IL122464A/en not_active IP Right Cessation
- 1996-06-03 TR TR97/01502T patent/TR199701502T1/en unknown
- 1996-06-03 CN CN96196149A patent/CN1097051C/en not_active Expired - Fee Related
- 1996-06-03 DE DE69617236T patent/DE69617236T2/en not_active Expired - Lifetime
- 1996-06-04 MY MYPI96002166A patent/MY114926A/en unknown
- 1996-06-04 US US08/658,969 patent/US5866568A/en not_active Expired - Lifetime
- 1996-06-04 AR ARP960102899A patent/AR003132A1/en active IP Right Grant
- 1996-06-04 TW TW085106632A patent/TW340845B/en not_active IP Right Cessation
- 1996-06-06 HR HR960272A patent/HRP960272B1/en not_active IP Right Cessation
- 1996-06-06 EG EG50996A patent/EG25227A/en active
1997
- 1997-12-05 NO NO19975700A patent/NO314503B1/en not_active IP Right Cessation
1998
- 1998-12-14 US US09/211,483 patent/US6060475A/en not_active Expired - Lifetime
2000
- 2000-02-15 US US09/504,364 patent/US6258817B1/en not_active Expired - Lifetime
2004
- 2004-07-19 GE GE5624A patent/GEP20053470B/en unknown

Also Published As

Publication number	Publication date
SK282338B6 (en)	2002-01-07
NO314503B1 (en)	2003-03-31
CZ289387B6 (en)	2002-01-16
MY114926A (en)	2003-02-28
DK0832082T3 (en)	2002-05-21
TW340845B (en)	1998-09-21
CZ388797A3 (en)	1998-03-18
PL187897B1 (en)	2004-10-29
GEP20053470B (en)	2005-02-25
CN1192739A (en)	1998-09-09
BR9608611A (en)	1999-05-11
NO975700L (en)	1997-12-05
CA2219742A1 (en)	1996-12-19
NZ308619A (en)	2000-01-28
DE69617236T2 (en)	2002-07-11
EP0832082B1 (en)	2001-11-21
SK168097A3 (en)	1998-05-06
EG25227A (en)	2011-11-17
UA58494C2 (en)	2003-08-15
CN1097051C (en)	2002-12-25
PL324660A1 (en)	1998-06-08
JP3193058B2 (en)	2001-07-30
NO975700D0 (en)	1997-12-05
US5866568A (en)	1999-02-02
US6060475A (en)	2000-05-09
AU5840396A (en)	1996-12-30
KR19990022327A (en)	1999-03-25
CA2219742C (en)	2007-01-16
AU715041B2 (en)	2000-01-13
HRP960272B1 (en)	2006-06-30
US6258817B1 (en)	2001-07-10
IL122464A0 (en)	1998-09-15
HUP9802300A2 (en)	1999-10-28
EP0832082A1 (en)	1998-04-01
KR100451523B1 (en)	2004-12-03
DE69617236D1 (en)	2002-01-03
HRP960272A2 (en)	1997-08-31
RU2172738C2 (en)	2001-08-27
AR003132A1 (en)	1998-07-08
HUP9802300A3 (en)	2002-02-28
IL122464A (en)	2002-05-23
JPH11509175A (en)	1999-08-17
TR199701502T1 (en)	1998-03-21
ES2168487T3 (en)	2002-06-16
HK1005801A1 (en)	1999-01-29
MX9709521A (en)	1998-03-31
WO1996040681A1 (en)	1996-12-19
ATE209200T1 (en)	2001-12-15

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