PT81898B - Processo para a preparacao de tieno-triazolo-1,4-diazepino-2-carboxamidas e de composicoes farmaceuticas contendo estes compostos - Google Patents

Processo para a preparacao de tieno-triazolo-1,4-diazepino-2-carboxamidas e de composicoes farmaceuticas contendo estes compostos

Info

Publication number: PT81898B
Authority: PT; Portugal
Prior art keywords: carbon atoms; halogen; diazepino; triazolo; thyo
Prior art date: 1985-01-25

Application number

PT81898A

Other languages

English (en)

Other versions

PT81898A (de

Original Assignee

Boehringer Ingelheim Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-25

Filing date

1986-01-24

Publication date

1988-05-27

1986-01-24 Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg

1986-02-01 Publication of PT81898A publication Critical patent/PT81898A/pt

1988-05-27 Publication of PT81898B publication Critical patent/PT81898B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT81898A 1985-01-25 1986-01-24 Processo para a preparacao de tieno-triazolo-1,4-diazepino-2-carboxamidas e de composicoes farmaceuticas contendo estes compostos PT81898B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19853502392 DE3502392A1 (de)	1985-01-25	1985-01-25	Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Publications (2)

Publication Number	Publication Date
PT81898A PT81898A (de)	1986-02-01
PT81898B true PT81898B (pt)	1988-05-27

Family

ID=6260695

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT81898A PT81898B (pt)	1985-01-25	1986-01-24	Processo para a preparacao de tieno-triazolo-1,4-diazepino-2-carboxamidas e de composicoes farmaceuticas contendo estes compostos

Country Status (28)

Country	Link
US (3)	US4968794A (pt)
EP (1)	EP0194416B1 (pt)
JP (2)	JPH0633278B2 (pt)
KR (1)	KR920010711B1 (pt)
AT (1)	ATE42556T1 (pt)
AU (1)	AU584663B2 (pt)
CA (1)	CA1269373A (pt)
CS (1)	CS254992B2 (pt)
CZ (1)	CZ410791A3 (pt)
DD (3)	DD263063A5 (pt)
DE (2)	DE3502392A1 (pt)
DK (2)	DK165323C (pt)
ES (3)	ES8704949A1 (pt)
FI (1)	FI86851C (pt)
GR (1)	GR860189B (pt)
HK (1)	HK75792A (pt)
HU (2)	HU193624B (pt)
IE (1)	IE58728B1 (pt)
IL (1)	IL77702A (pt)
MX (1)	MX9203258A (pt)
NO (2)	NO164029C (pt)
NZ (1)	NZ214926A (pt)
PL (1)	PL144948B1 (pt)
PT (1)	PT81898B (pt)
SG (1)	SG44292G (pt)
SU (1)	SU1402265A3 (pt)
YU (2)	YU44280B (pt)
ZA (1)	ZA86542B (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3502392A1 (de) *	1985-01-25	1986-07-31	Boehringer Ingelheim KG, 6507 Ingelheim	Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3778559D1 (de) *	1986-01-21	1992-06-04	Boehringer Ingelheim Kg	Thieno-1,4-diazepine.
DE3610848A1 (de) *	1986-04-01	1987-10-15	Boehringer Ingelheim Kg	Neue 1,4-diazepine
PH30676A (en) *	1986-07-22	1997-09-16	Boehringer Ingelhein Kg	Hetrazepine compounds which have useful pharmaceutical utility
DE3745135C2 (de) *	1986-10-21	1999-05-12	Korth Ruth	Verwendung von hydrophilen Triazolothieno-diazepinen zur Behandlung von Arteriosklerose
EP0268242B1 (en) *	1986-11-17	1992-03-18	Yoshitomi Pharmaceutical Industries, Ltd.	Paf-antagonistic thienotriazolodiazepine compounds and pharmaceutical uses thereof
DE3725130C2 (de) *	1987-07-29	1996-12-12	Boehringer Ingelheim Kg	Tritium-oder ·1··4·C-markiertes 4-(2-Chlorphenyl)-9-methyl-2-[3-(4-morpholinyl)-3-propanon-1-yl]-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin, Verfahren zu deren Herstellung und deren Verwendung als Radiorezeptorassay sowie zu diagnostischen Zwecken
US5895785A (en) *	1987-10-20	1999-04-20	Ruth Korth	Treatment and prevention of disorders mediated by LA-paf or endothelial cells
US4959361A (en) *	1987-12-18	1990-09-25	Hoffmann-La Roche Inc.	Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists
CA1324863C (en) *	1988-01-30	1993-11-30	Minoru Moriwaki	Thienotriazolodiazepine compounds and pharmaceutical uses thereof
EP0338993A1 (en) *	1988-04-21	1989-10-25	Sandoz Ag	6-Aryl-substituted-4h-thieno[2,3-e][1,2,4]triazolo [3,4-c][1,4]diazepines
US5334592A (en) *	1988-04-27	1994-08-02	Schering Corporation	Certain PAF antagonist antihistamine combinations and methods
ATE84724T1 (de) *	1988-04-27	1993-02-15	Schering Corp	Gewisse paf-antagonist/antihistamin-mischungen und verfahren.
CA1322367C (en) *	1988-05-17	1993-09-21	Yoshitomi Pharmaceutical Industries Ltd.	Thienotriazolodiazepine compounds and pharmaceutical uses thereof
FI95708C (fi) *	1988-10-31	1996-03-11	Eisai Co Ltd	Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
US5221671A (en) *	1988-10-31	1993-06-22	Eisai Co., Ltd.	Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5304553A (en) *	1988-10-31	1994-04-19	Eisai Co., Ltd.	1,4-diazepine derivative and its pharmaceutical use
US5468740A (en) *	1988-10-31	1995-11-21	Eisai Co., Ltd.	1,4-diazepine derivative and its pharmaceutical use
US5382579A (en) *	1988-10-31	1995-01-17	Eisai Co., Ltd.	Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
RU2117670C1 (ru) *	1988-10-31	1998-08-20	Эйсай Ко., Лтд.	Производные триазоло[1,4]диазепина и способы их получения
EP0387613A1 (de) *	1989-03-03	1990-09-19	Boehringer Ingelheim Kg	Neue Thienodiazepine
DE4010528A1 (de) *	1990-04-02	1991-10-17	Boehringer Ingelheim Kg	Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
ES2095316T3 (es) *	1990-05-31	1997-02-16	Allergan Inc	Uso de antagonistas del factor activador de plaquetas como agentes antipruriticos.
DE4027470A1 (de) *	1990-08-30	1992-03-05	Boehringer Ingelheim Kg	Neue hetrazepinoide amide
DE4128579A1 (de) *	1991-08-28	1993-03-04	Boehringer Ingelheim Kg	Verwendung von 4-(2-chlorphenyl)-9-methyl-2-(3(4-morpholinyl)-3-propanon-1-y1)-6h-thieno-(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin zur behandlung der allergischen rhinitis
ATE221779T1 (de) *	1991-11-04	2002-08-15	Ruth-Maria Korth	Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten
TW219935B (pt) *	1991-12-25	1994-02-01	Mitsubishi Chemicals Co Ltd
DE4200619A1 (de) *	1992-01-13	1993-07-15	Boehringer Ingelheim Kg	Verwendung von 4-(2-chlorphenyl)-9-methyl-2-/3(4-morpholinyl)-3-propanon-1-yl/-6h-thieno-/3,2-f//1,2,4/ triazolo/4,3-a//1,4/diazepin zur behandlung der dysmenorrhes
GB9207645D0 (en) *	1992-04-08	1992-05-27	Smithkline Beecham Corp	Methods
WO1994004537A2 (en) *	1992-08-20	1994-03-03	Cytomed, Inc.	Dual functional anti-inflammatory and immunosuppressive agents
US5288514A (en) *	1992-09-14	1994-02-22	The Regents Of The University Of California	Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5302590A (en) *	1992-12-18	1994-04-12	Hoffmann-La Roche Inc.	Compounds useful as dual antagonists of platelet activating factor and leukotriene D4
HUT77348A (hu) *	1994-11-08	1998-03-30	Takeda Chemical Industries, Ltd.	Tienopiridin- és tienopirimidinszármazékok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények
EP0995752A4 (en)	1997-06-25	2001-08-16	Nikken Chemicals Co Ltd	TIRAZOLO-1,4-DIAZEPINE DERIVATIVES AND MEDICAL PREPARATION CONTAINING THEM
BRPI0410840A (pt)	2003-05-30	2006-07-04	Ranbaxy Lab Ltd	derivados substituìdos de pirrol, composição farmacêutica contendo os mesmos e processo para sua preparação
US7223167B2 (en) *	2005-04-01	2007-05-29	Cnh America Llc	Anti-wind wiper with adjustable extension
EP1948599A1 (en)	2005-11-08	2008-07-30	Ranbaxy Laboratories Limited	Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US9638493B2 (en)	2011-11-26	2017-05-02	Orval E. Bowman	Pointing devices, apparatus, systems and methods for high shock environments
US11766443B2 (en)	2020-11-16	2023-09-26	Boehringer Ingelheim International Gmbh	Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists
EP4452985A1 (en)	2021-12-22	2024-10-30	Boehringer Ingelheim International Gmbh	Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH12303A (en) *	1973-02-08	1979-01-16	Hoffmann La Roche	Thienotriazolodiazepine derivatives
DE2503235A1 (de) *	1975-01-27	1976-07-29	Boehringer Sohn Ingelheim	Neues verfahren zur herstellung von 8-brom-thieno-triazolo-1,4-diazepinen
US4201712A (en) *	1975-07-16	1980-05-06	Boehringer Ingelheim Gmbh	Process for preparation of 6-aryl-4H-s-triazolo-[3,4-c]-thieno-[2,3-e]-1,4-diazepines
AU518438B2 (en) *	1978-04-26	1981-10-01	Boehringer Ingelheim International Gmbh	Substituted 6-aryl-4h-s-triazolo-3,4-c-thieno-2,3-e-1,4-diazepines
AU520063B2 (en) *	1978-07-13	1982-01-14	Boehringer Ingelheim International Gmbh	Substituted 4h-s-triazolo(3,4-c)thieno(2,3-e)1,4-diazepines
DE3435973A1 (de) *	1984-10-01	1986-04-10	Boehringer Ingelheim KG, 6507 Ingelheim	Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
DE3502392A1 (de) *	1985-01-25	1986-07-31	Boehringer Ingelheim KG, 6507 Ingelheim	Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3778559D1 (de) *	1986-01-21	1992-06-04	Boehringer Ingelheim Kg	Thieno-1,4-diazepine.
WO1988009333A1 (fr) *	1987-05-28	1988-12-01	Yoshitomi Pharmaceutical Industries, Ltd.	Compose a base de thieno(triazolo)diazepine et applications medicales de ce compose
US4959361A (en) *	1987-12-18	1990-09-25	Hoffmann-La Roche Inc.	Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists
US4914096A (en) *	1988-04-21	1990-04-03	Sandoz Pharmaceuticals Corp.	6-aryl-substituted-4H-thieno(2,3-e)(1,2,4)triazolo(3,4-c)(1,4)diazepines

1985
- 1985-01-25 DE DE19853502392 patent/DE3502392A1/de not_active Withdrawn
- 1985-12-23 NO NO855260A patent/NO164029C/no unknown
1986
- 1986-01-16 SU SU864008368A patent/SU1402265A3/ru active
- 1986-01-20 DE DE8686100656T patent/DE3663028D1/de not_active Expired
- 1986-01-20 EP EP86100656A patent/EP0194416B1/de not_active Expired
- 1986-01-20 AT AT86100656T patent/ATE42556T1/de not_active IP Right Cessation
- 1986-01-20 YU YU78/86A patent/YU44280B/xx unknown
- 1986-01-21 CS CS86452A patent/CS254992B2/cs not_active IP Right Cessation
- 1986-01-22 FI FI860296A patent/FI86851C/fi not_active IP Right Cessation
- 1986-01-23 DD DD86286429A patent/DD263063A5/de unknown
- 1986-01-23 PL PL1986257602A patent/PL144948B1/pl unknown
- 1986-01-23 DD DD86311011A patent/DD265899A5/de not_active IP Right Cessation
- 1986-01-23 DD DD86311014A patent/DD265799A5/de not_active IP Right Cessation
- 1986-01-23 GR GR860189A patent/GR860189B/el not_active IP Right Cessation
- 1986-01-24 IL IL77702A patent/IL77702A/xx not_active IP Right Cessation
- 1986-01-24 AU AU52728/86A patent/AU584663B2/en not_active Ceased
- 1986-01-24 JP JP61013605A patent/JPH0633278B2/ja not_active Expired - Fee Related
- 1986-01-24 IE IE20986A patent/IE58728B1/en not_active IP Right Cessation
- 1986-01-24 DK DK036786A patent/DK165323C/da not_active IP Right Cessation
- 1986-01-24 ES ES551198A patent/ES8704949A1/es not_active Expired
- 1986-01-24 HU HU86356A patent/HU193624B/hu not_active IP Right Cessation
- 1986-01-24 ZA ZA85542A patent/ZA86542B/xx unknown
- 1986-01-24 CA CA000500345A patent/CA1269373A/en not_active Expired - Fee Related
- 1986-01-24 KR KR1019860000445A patent/KR920010711B1/ko not_active Expired
- 1986-01-24 PT PT81898A patent/PT81898B/pt not_active IP Right Cessation
- 1986-01-24 NZ NZ214926A patent/NZ214926A/xx unknown
- 1986-01-24 HU HU852044A patent/HU195821B/hu not_active IP Right Cessation
1987
- 1987-01-21 ES ES557344A patent/ES8802523A1/es not_active Expired
- 1987-01-21 ES ES557343A patent/ES8802426A1/es not_active Expired
- 1987-05-05 YU YU79987A patent/YU46049B/sh unknown
1988
- 1988-10-03 US US07/252,725 patent/US4968794A/en not_active Expired - Lifetime
1989
- 1989-09-13 JP JP1238305A patent/JPH0651704B2/ja not_active Expired - Fee Related
- 1989-11-22 NO NO894640A patent/NO166646C/no unknown
1990
- 1990-06-15 US US07/539,416 patent/US5082839A/en not_active Expired - Lifetime
1991
- 1991-10-11 US US07/774,683 patent/US5155103A/en not_active Expired - Fee Related
- 1991-12-27 CZ CS914107A patent/CZ410791A3/cs unknown
1992
- 1992-04-06 DK DK046292A patent/DK46292A/da not_active Application Discontinuation
- 1992-04-22 SG SG442/92A patent/SG44292G/en unknown
- 1992-06-24 MX MX9203258A patent/MX9203258A/es unknown
- 1992-10-01 HK HK757/92A patent/HK75792A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
US4968794A (en)	1990-11-06
HK75792A (en)	1992-10-09
ES8704949A1 (es)	1987-04-16
IL77702A (en)	1989-02-28
YU46049B (sh)	1992-12-21
MX9203258A (es)	1992-07-01
DE3663028D1 (en)	1989-06-01
DK36786A (da)	1986-07-26
IE58728B1 (en)	1993-11-03
ES557344A0 (es)	1988-07-16
NO164029B (no)	1990-05-14
ES557343A0 (es)	1988-06-01
DK46292D0 (da)	1992-04-06
FI86851C (fi)	1992-10-26
ES551198A0 (es)	1987-04-16
ZA86542B (en)	1987-09-30
NO894640D0 (no)	1989-11-22
KR920010711B1 (ko)	1992-12-14
JPH02191281A (ja)	1990-07-27
NO855260L (no)	1986-07-28
ATE42556T1 (de)	1989-05-15
CS254992B2 (en)	1988-02-15
DD265799A5 (de)	1989-03-15
HU193624B (en)	1987-11-30
FI86851B (fi)	1992-07-15
DK165323B (da)	1992-11-09
DK46292A (da)	1992-04-06
IE860209L (en)	1986-07-25
HUT40441A (en)	1986-12-28
ES8802426A1 (es)	1988-06-01
HU195821B (en)	1988-07-28
AU5272886A (en)	1986-07-31
PL257602A1 (en)	1987-05-04
PL144948B1 (en)	1988-07-30
DK165323C (da)	1993-03-29
NO166646B (no)	1991-05-13
SU1402265A3 (ru)	1988-06-07
JPH0651704B2 (ja)	1994-07-06
CA1269373A (en)	1990-05-22
AU584663B2 (en)	1989-06-01
SG44292G (en)	1992-09-04
EP0194416B1 (de)	1989-04-26
JPS61176591A (ja)	1986-08-08
DD265899A5 (de)	1989-03-15
YU79987A (en)	1988-06-30
NZ214926A (en)	1989-04-26
EP0194416A1 (de)	1986-09-17
PT81898A (de)	1986-02-01
NO894640L (no)	1986-07-28
YU44280B (en)	1990-04-30
FI860296L (fi)	1986-07-26
GR860189B (en)	1986-05-26
NO164029C (no)	1990-08-22
DD263063A5 (de)	1988-12-21
NO166646C (no)	1991-08-21
DE3502392A1 (de)	1986-07-31
YU7886A (en)	1987-10-31
FI860296A0 (fi)	1986-01-22
KR860005822A (ko)	1986-08-13
JPH0633278B2 (ja)	1994-05-02
CZ410791A3 (en)	1993-04-14
US5155103A (en)	1992-10-13
DK36786D0 (da)	1986-01-24
ES8802523A1 (es)	1988-07-16
US5082839A (en)	1992-01-21

Publication	Publication Date	Title
PT81898B (pt)	1988-05-27	Processo para a preparacao de tieno-triazolo-1,4-diazepino-2-carboxamidas e de composicoes farmaceuticas contendo estes compostos
DE3069408D1 (en)	1984-11-15	5-oxo- and 5-thioxoproline derivatives, process for their production and pharmaceutical compositions containing them
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