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PT80577B - Processo para a producao de novos agentes macrolidos ll-f28249 uteis no tratamento de infeccoes helminticas por ectoparasitas artropodes e por acarideos - Google Patents

Processo para a producao de novos agentes macrolidos ll-f28249 uteis no tratamento de infeccoes helminticas por ectoparasitas artropodes e por acarideos

Info

Publication number
PT80577B
PT80577B PT80577A PT8057785A PT80577B PT 80577 B PT80577 B PT 80577B PT 80577 A PT80577 A PT 80577A PT 8057785 A PT8057785 A PT 8057785A PT 80577 B PT80577 B PT 80577B
Authority
PT
Portugal
Prior art keywords
helmintical
ectoparasitas
acarideos
uteis
arthropodes
Prior art date
Application number
PT80577A
Other languages
English (en)
Other versions
PT80577A (en
Inventor
Guy Thomas Carter
Irwin Boyden Wood
Michael Greenstein
John Anthony Pankavich
Margareth Jennings Torrey
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/617,649 external-priority patent/US4869901A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PT80577A publication Critical patent/PT80577A/pt
Publication of PT80577B publication Critical patent/PT80577B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
    • A01N63/28—Streptomyces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Agronomy & Crop Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Fodder In General (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Protection Of Plants (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT80577A 1984-06-05 1985-06-03 Processo para a producao de novos agentes macrolidos ll-f28249 uteis no tratamento de infeccoes helminticas por ectoparasitas artropodes e por acarideos PT80577B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61765084A 1984-06-05 1984-06-05
US06/617,649 US4869901A (en) 1984-06-05 1984-06-05 Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents

Publications (2)

Publication Number Publication Date
PT80577A PT80577A (en) 1985-07-01
PT80577B true PT80577B (pt) 1987-09-18

Family

ID=27088071

Family Applications (1)

Application Number Title Priority Date Filing Date
PT80577A PT80577B (pt) 1984-06-05 1985-06-03 Processo para a producao de novos agentes macrolidos ll-f28249 uteis no tratamento de infeccoes helminticas por ectoparasitas artropodes e por acarideos

Country Status (9)

Country Link
EP (1) EP0170006B1 (pt)
JP (2) JPH0776223B2 (pt)
AU (1) AU588811B2 (pt)
DE (1) DE3519834C2 (pt)
DK (4) DK165119C (pt)
ES (1) ES8703159A1 (pt)
HU (1) HU199900B (pt)
IE (1) IE58100B1 (pt)
PT (1) PT80577B (pt)

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AR240943A1 (es) * 1985-02-05 1991-03-27 Sankio Company Limited Nuevo compuesto agroquimico denominado "sustancia n*51262" procedimiento para prepararlo y composicion que lo comprende"
IL78621A (en) * 1985-04-30 1991-06-30 American Cyanamid Co Mylbemycin analogs,their preparation and pesticidal compositions containing them
AU598204B2 (en) * 1985-09-13 1990-06-21 American Cyanamid Company Chemical derivatives of antibiotics S541
EP0238258B1 (en) * 1986-03-12 1994-01-26 American Cyanamid Company Macrolide compounds
GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
GB8606116D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
EP0242052B1 (en) * 1986-03-12 1993-04-21 American Cyanamid Company Macrolide compounds
GB8606122D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
GB8606123D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
GB8606105D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
AT398312B (de) * 1986-03-12 1994-11-25 American Cyanamid Co Verfahren zur herstellung einer neuen makroliden verbindung
US5185456A (en) * 1986-03-12 1993-02-09 American Cyanamid Company Macrolide compounds
GB2187742B (en) * 1986-03-12 1990-05-23 Glaxo Group Ltd Macrolide compound
IE62125B1 (en) * 1986-03-12 1994-12-14 American Cyanamid Co Macrolide compounds
US5336789A (en) * 1986-03-12 1994-08-09 American Cyanamid Company Macrolide compounds
NZ219575A (en) * 1986-03-12 1990-04-26 Glaxo Group Ltd Phosphate, substituted alkoxy, or amino-carbonyloxy derivatives of milbemycin, and pesticidal compositions
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
NZ221077A (en) * 1986-07-18 1990-06-26 Ciba Geigy Ag 13b-alkyl milbemycins and use as parasiticides
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US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
EP0259779B1 (en) * 1986-09-12 1994-08-10 American Cyanamid Company 23-Oxo (Keto) and 23-imino Derivatives of LL-F28249 Compounds
US5149832A (en) * 1986-09-12 1992-09-22 American Cyanamid Company Mono and diacyl derivatives of ll-f28249 compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
US5019589A (en) * 1986-09-12 1991-05-28 American Cyanamid Company Δ23 -LL-F28249 compounds
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4956479A (en) * 1987-03-06 1990-09-11 American Cyanamid Company 23-deoxy-27-chloro derivatives of LL-F28249 compounds
US4857544A (en) * 1987-03-06 1989-08-15 American Cyanamid Company 27-Halo derivatives of LL-F28249 compounds
US4851428A (en) * 1987-03-06 1989-07-25 American Cyanamid Company Mono- and diepoxide derivatives of Δ22-LL-F28249 compounds
US4886830A (en) * 1987-03-06 1989-12-12 American Cyanamid Company Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
EP0285561A3 (de) * 1987-03-27 1989-10-25 Ciba-Geigy Ag Parasitizide und insektizide Milbemycin-Derivate
NZ225364A (en) * 1987-07-20 1990-04-26 Merck & Co Inc 5,23-di-hydroxy 25-(4-methyl-hex-2-en-2-yl) milbemycin and parasiticidal compositions
JPS6431776A (en) * 1987-07-28 1989-02-02 Sankyo Co Novel macrolide compound and production thereof
GB8721371D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8721647D0 (en) * 1987-09-15 1987-10-21 Pfizer Ltd Antiparasitic agents
DE3888936T2 (de) * 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
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US5008250A (en) * 1988-05-25 1991-04-16 Merck & Co., Inc. Avermectins with a cleaved furan ring and an 8a hydroxy group
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US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US5015662A (en) * 1988-10-18 1991-05-14 Merck & Co., Inc. Anthelmintic bioconversion products
NZ232422A (en) * 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
DE69007515T2 (de) * 1989-02-28 1994-11-03 American Cyanamid Co Bolus mit lang andauernder Wirkstoffabgabe, wirksam bei der Prophylaxe, Behandlung oder Bekämpfung des Befalls bei Wiederkäuern durch Fadenwürmer, Milben und Endo- und Ektoparasiten.
GB8917064D0 (en) * 1989-07-26 1989-09-13 Pfizer Ltd Antiparasitic agent
US5030650A (en) * 1989-09-11 1991-07-09 American Cyanamid Company 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
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DE60118132T2 (de) 2000-10-10 2006-10-19 Wyeth Anthelmintika
US7772194B2 (en) 2001-09-17 2010-08-10 Eli Lilly And Company Pesticidal formulations
EP2327410A1 (en) * 2009-10-28 2011-06-01 Consiglio Nazionale Delle Ricerche - Infm Istituto Nazionale Per La Fisica Della Materia Avermectins and milbemycins for the treatment of flavivirus infections
WO2011075592A1 (en) 2009-12-17 2011-06-23 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
CN103242338B (zh) * 2013-05-07 2015-03-04 东北农业大学 一种大环内酯类化合物及其制备方法和应用
CN103588784B (zh) * 2013-11-14 2015-12-30 大连九信生物化工科技有限公司 一种制备高纯度尼莫克汀的方法

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Also Published As

Publication number Publication date
DK53691A (da) 1991-03-25
DK165461C (da) 1993-04-13
DK248885D0 (da) 1985-06-03
DE3519834C2 (de) 1993-12-16
PT80577A (en) 1985-07-01
DK51991D0 (da) 1991-03-22
DK53591D0 (da) 1991-03-25
DK165210C (da) 1993-03-22
DK51991A (da) 1991-03-22
DK165436B (da) 1992-11-30
DK53691D0 (da) 1991-03-25
HU199900B (en) 1990-03-28
ES8703159A1 (es) 1987-02-01
ES543948A0 (es) 1987-02-01
DE3519834A1 (de) 1986-03-27
DK53591A (da) 1991-03-25
EP0170006A2 (en) 1986-02-05
DK165210B (da) 1992-10-26
JPH07233170A (ja) 1995-09-05
IE58100B1 (en) 1993-06-30
JPH0776223B2 (ja) 1995-08-16
DK165119C (da) 1993-03-01
DK165119B (da) 1992-10-12
HUT43637A (en) 1987-11-30
DK248885A (da) 1985-12-06
IE851391L (en) 1985-12-05
JPS6110589A (ja) 1986-01-18
EP0170006B1 (en) 1992-07-08
JP2524688B2 (ja) 1996-08-14
EP0170006A3 (en) 1988-07-20
DK165461B (da) 1992-11-30
AU4328385A (en) 1985-12-12
DK165436C (da) 1993-04-13
AU588811B2 (en) 1989-09-28

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Legal Events

Date Code Title Description
PD3A Change of proprietorship

Free format text: WYETH HOLDINGS CORPORATION US

Effective date: 20031117

TE3A Change of address (patent)

Free format text: AMERICAN CYANAMID COMPANY US

Effective date: 20031117