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PT789767E - Processo para a producao de proteinas de papilomavirus purificadas - Google Patents

Processo para a producao de proteinas de papilomavirus purificadas

Info

Publication number
PT789767E
PT789767E PT95942431T PT95942431T PT789767E PT 789767 E PT789767 E PT 789767E PT 95942431 T PT95942431 T PT 95942431T PT 95942431 T PT95942431 T PT 95942431T PT 789767 E PT789767 E PT 789767E
Authority
PT
Portugal
Prior art keywords
papilomavirus
proteins
purified
production
purified papilomavirus
Prior art date
Application number
PT95942431T
Other languages
English (en)
Inventor
Kathryn J Hofmann
Henry Z Markus
Loren D Schultz
Ernest D Lehman
James C Cook
Hugh A George
Kathrin U Jansen
Joseph G Joyce
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT789767E publication Critical patent/PT789767E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PT95942431T 1994-11-14 1995-11-13 Processo para a producao de proteinas de papilomavirus purificadas PT789767E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33936894A 1994-11-14 1994-11-14

Publications (1)

Publication Number Publication Date
PT789767E true PT789767E (pt) 2003-11-28

Family

ID=23328696

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95942431T PT789767E (pt) 1994-11-14 1995-11-13 Processo para a producao de proteinas de papilomavirus purificadas

Country Status (23)

Country Link
EP (1) EP0789767B1 (pt)
JP (1) JPH11500002A (pt)
KR (1) KR987000420A (pt)
CN (1) CN1173203A (pt)
AR (1) AR004464A1 (pt)
AT (1) ATE245192T1 (pt)
AU (1) AU708737B2 (pt)
BR (1) BR9510520A (pt)
CZ (1) CZ145297A3 (pt)
DE (1) DE69531308T2 (pt)
DK (1) DK0789767T3 (pt)
ES (1) ES2201129T3 (pt)
FI (1) FI972030L (pt)
HR (1) HRP950557A2 (pt)
HU (1) HUT77559A (pt)
MX (1) MX9703570A (pt)
NZ (1) NZ298224A (pt)
PT (1) PT789767E (pt)
RU (1) RU2161651C2 (pt)
SK (1) SK281878B6 (pt)
UA (1) UA35639C2 (pt)
WO (1) WO1996015247A1 (pt)
YU (1) YU71195A (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153201A (en) * 1993-03-09 2000-11-28 University Of Rochester Oral immunization with papillomavirus virus-like particles
NZ293461A (en) * 1994-09-22 1998-04-27 Merck & Co Inc Dna encoding human papillomavirus type 6a, compounds derived therefrom
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
DK0973546T3 (da) * 1997-04-08 2004-06-28 Merck & Co Inc Stabiliserede formuleringer med human papillomavirus
ES2262333T3 (es) * 1998-08-14 2006-11-16 MERCK & CO., INC. Procedimiento para purificar particulas similares a virus de papilomavirus humano.
AUPP765398A0 (en) 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
EP1150712B1 (en) 1999-02-05 2008-11-05 Merck & Co., Inc. Human papilloma virus vaccine formulations
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
NZ535944A (en) 2002-04-30 2007-11-30 Oncolytics Biotech Inc Viral purification method comprising a simple extraction step in which a detergent is directly added to the cell culture, thereafter, cell debris is removed from the extraction mixture by filtration or centrifugation
NZ542246A (en) * 2003-03-24 2007-12-21 Merck & Co Inc Optimized expression of HPV 31 L1 yeast
RU2251699C1 (ru) * 2003-09-25 2005-05-10 Киселев Всеволод Иванович Способ ранней и доклинической диагностики цервикального рака
MY140664A (en) * 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
SG10201701988TA (en) * 2007-03-14 2017-04-27 Ligocyte Pharmaceuticals Inc Virus like particle purification
RU2377305C1 (ru) * 2008-11-13 2009-12-27 Всеволод Иванович Киселев Мукозальная вакцина для иммунотерапии заболеваний, обусловленных вирусами папилломы человека, и способ лечения с ее использованием (варианты)
CN102215861B (zh) * 2009-06-19 2014-10-08 艾金株式会社 宫颈癌疫苗
JOP20130186B1 (ar) 2012-06-22 2021-08-17 Takeda Vaccines Montana Inc تنقية الجزيئات الشبيهة بالفيروسات
CN103936840B (zh) * 2013-01-18 2019-04-09 北京康乐卫士生物技术股份有限公司 重组的人乳头瘤病毒33型l1蛋白及其用途
CN113278064B (zh) * 2021-07-20 2021-11-02 山东信得科技股份有限公司 一种用于胚毒类抗原净化处理的方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000023I1 (de) * 1991-07-19 2007-08-09 Univ Queensland St Lucia Impfsstoff gegen Humanes Papillomavirus (typ 18)
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
ES2242955T4 (es) * 1993-03-09 2010-04-12 The University Of Rochester Produccion de la proteina de la capside del virus del papiloma humano y particulas de tipo viral.
RO117541B1 (ro) * 1994-05-16 2002-04-30 Merck & Co Inc Procedeu pentru prepararea unui vaccin de papillomavirus uman, pentru administrare la om

Also Published As

Publication number Publication date
FI972030A0 (fi) 1997-05-13
KR987000420A (ko) 1998-03-30
FI972030A7 (fi) 1997-05-13
SK281878B6 (sk) 2001-08-06
EP0789767A1 (en) 1997-08-20
HUT77559A (hu) 1998-06-29
DE69531308T2 (de) 2004-04-15
NZ298224A (en) 1999-05-28
WO1996015247A1 (en) 1996-05-23
MX9703570A (es) 1997-08-30
ES2201129T3 (es) 2004-03-16
ATE245192T1 (de) 2003-08-15
CN1173203A (zh) 1998-02-11
JPH11500002A (ja) 1999-01-06
FI972030L (fi) 1997-05-13
RU2161651C2 (ru) 2001-01-10
BR9510520A (pt) 1998-07-14
CZ145297A3 (en) 1997-10-15
AU708737B2 (en) 1999-08-12
UA35639C2 (uk) 2001-04-16
HRP950557A2 (en) 1997-08-31
AU4365896A (en) 1996-06-06
DK0789767T3 (da) 2003-10-20
YU71195A (sh) 1999-06-15
AR004464A1 (es) 1998-12-16
SK59497A3 (en) 1998-03-04
EP0789767B1 (en) 2003-07-16
DE69531308D1 (de) 2003-08-21

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