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PT788350E - Formacao de particulas pequenas - Google Patents

Formacao de particulas pequenas

Info

Publication number
PT788350E
PT788350E PT95938091T PT95938091T PT788350E PT 788350 E PT788350 E PT 788350E PT 95938091 T PT95938091 T PT 95938091T PT 95938091 T PT95938091 T PT 95938091T PT 788350 E PT788350 E PT 788350E
Authority
PT
Portugal
Prior art keywords
pct
formation
small particles
date
sec
Prior art date
Application number
PT95938091T
Other languages
English (en)
Inventor
Jan-Erik Lofroth
Sylvan Frank
Levon Bostanian
Original Assignee
Univ Ohio State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ohio State Res Found filed Critical Univ Ohio State Res Found
Publication of PT788350E publication Critical patent/PT788350E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/10—Complex coacervation, i.e. interaction of oppositely charged particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Saccharide Compounds (AREA)
  • Soft Magnetic Materials (AREA)
  • Confectionery (AREA)
  • Surgical Instruments (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Steroid Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
PT95938091T 1994-11-09 1995-11-03 Formacao de particulas pequenas PT788350E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9403846A SE9403846D0 (sv) 1994-11-09 1994-11-09 Small particle formation

Publications (1)

Publication Number Publication Date
PT788350E true PT788350E (pt) 2002-07-31

Family

ID=20395907

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95938091T PT788350E (pt) 1994-11-09 1995-11-03 Formacao de particulas pequenas

Country Status (27)

Country Link
US (1) US5780062A (pt)
EP (1) EP0788350B1 (pt)
JP (1) JP4098827B2 (pt)
KR (1) KR970706799A (pt)
CN (1) CN1165478A (pt)
AT (1) ATE213625T1 (pt)
AU (1) AU700644B2 (pt)
BR (1) BR9509720A (pt)
CA (1) CA2203512A1 (pt)
CZ (1) CZ129597A3 (pt)
DE (1) DE69525639T2 (pt)
DK (1) DK0788350T3 (pt)
EE (1) EE9700214A (pt)
ES (1) ES2173204T3 (pt)
FI (1) FI118511B (pt)
HU (1) HUT77629A (pt)
IL (1) IL115878A0 (pt)
IS (1) IS4467A (pt)
NO (1) NO971986D0 (pt)
NZ (1) NZ295497A (pt)
PL (1) PL320425A1 (pt)
PT (1) PT788350E (pt)
SE (1) SE9403846D0 (pt)
SK (1) SK55997A3 (pt)
TR (1) TR199501400A2 (pt)
WO (1) WO1996014833A1 (pt)
ZA (1) ZA959386B (pt)

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US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
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US6977085B2 (en) 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US20030096013A1 (en) * 2000-12-22 2003-05-22 Jane Werling Preparation of submicron sized particles with polymorph control
US9700866B2 (en) * 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US6951656B2 (en) 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
ATE319432T1 (de) * 2000-12-22 2006-03-15 Baxter Int Verfahren zur herstellung von submikropartikel- suspensionen pharmazeutischer substanzen
DE10117049A1 (de) * 2001-04-05 2002-10-17 Novartis Ag Zusammensetzung
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WO2003026611A2 (en) 2001-09-26 2003-04-03 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
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US7511079B2 (en) * 2003-03-24 2009-03-31 Baxter International Inc. Methods and apparatuses for the comminution and stabilization of small particles
CN1791386A (zh) * 2003-05-19 2006-06-21 巴克斯特国际公司 抗癫痫和抗痴呆药物以及免疫抑制剂的小－颗粒药物制剂
US20060135523A1 (en) * 2003-06-18 2006-06-22 Astrazeneca Ab 2-substituted 5,6-diaryl-pyrazine derivatives as cb1 modulator
GB0314057D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
GB0314261D0 (en) * 2003-06-19 2003-07-23 Astrazeneca Ab Therapeutic agents
US8986736B2 (en) * 2003-06-24 2015-03-24 Baxter International Inc. Method for delivering particulate drugs to tissues
BRPI0414970A2 (pt) * 2003-06-24 2012-12-11 Baxter Int método para transporte de drogas ao cérebro
CN1905905B (zh) 2003-09-22 2011-06-08 巴克斯特国际公司 用于药物制剂和医药产品最终灭菌的高压灭菌
JP2007507527A (ja) * 2003-09-30 2007-03-29 スフェリックス， インコーポレイテッド 生物学的に活性なナノ粒子治療用因子
DE10351087A1 (de) * 2003-10-31 2005-05-25 Bayer Technology Services Gmbh Feste Wirkstoff-Formulierung
CA2554246A1 (en) * 2004-01-29 2005-08-11 Baxter International Inc. Nanosuspensions of anti-retroviral agents for increased central nervous system delivery
EP1711163A2 (en) * 2004-02-05 2006-10-18 Baxter International Inc. Dispersions prepared by use of self-stabilizing agents
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WO2008135855A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer
US8309129B2 (en) * 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US8530463B2 (en) * 2007-05-07 2013-09-10 Hale Biopharma Ventures Llc Multimodal particulate formulations
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CA1282405C (en) * 1984-05-21 1991-04-02 Michael R. Violante Method for making uniformly sized particles from water-insoluble organic compounds
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Also Published As

Publication number Publication date
NO971986L (no) 1997-04-29
EP0788350A1 (en) 1997-08-13
DE69525639T2 (de) 2002-08-29
DE69525639D1 (de) 2002-04-04
IL115878A0 (en) 1996-01-31
ZA959386B (en) 1996-05-09
ATE213625T1 (de) 2002-03-15
PL320425A1 (en) 1997-09-29
ES2173204T3 (es) 2002-10-16
SE9403846D0 (sv) 1994-11-09
IS4467A (is) 1997-04-21
HUT77629A (hu) 1998-06-29
CA2203512A1 (en) 1996-05-23
WO1996014833A1 (en) 1996-05-23
KR970706799A (ko) 1997-12-01
TR199501400A2 (tr) 1996-06-21
NO971986D0 (no) 1997-04-29
US5780062A (en) 1998-07-14
JPH10508840A (ja) 1998-09-02
FI971947L (fi) 1997-05-07
EP0788350B1 (en) 2002-02-27
AU700644B2 (en) 1999-01-14
CN1165478A (zh) 1997-11-19
SK55997A3 (en) 1998-01-14
DK0788350T3 (da) 2002-04-29
FI118511B (fi) 2007-12-14
BR9509720A (pt) 1997-10-21
JP4098827B2 (ja) 2008-06-11
FI971947A0 (fi) 1997-05-07
EE9700214A (et) 1998-04-15
NZ295497A (en) 1998-05-27
AU3885195A (en) 1996-06-06
CZ129597A3 (en) 1997-12-17

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