PT755249E - Utilizacao de inibidores da reaccao de maillard para o tratamento de doenca com base em amiloidose - Google Patents

Utilizacao de inibidores da reaccao de maillard para o tratamento de doenca com base em amiloidose

Info

Publication number: PT755249E
Authority: PT; Portugal
Prior art keywords: amiloidose; maillard reaction; disease treatment; based disease; reaction inhibitors
Prior art date: 1994-04-13

Application number

PT95915254T

Other languages

English (en)

Inventor

Camilo Colaco

Bruce Joseph Roser

Original Assignee

Elan Drug Delivery Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-13

Filing date

1995-04-13

Publication date

2004-08-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10753465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT755249(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-04-13 Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd

2004-08-31 Publication of PT755249E publication Critical patent/PT755249E/pt

Links

201000010099 disease Diseases 0.000 title abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
238000011282 treatment Methods 0.000 title abstract 2
239000002683 reaction inhibitor Substances 0.000 title 1
208000024827 Alzheimer disease Diseases 0.000 abstract 1
APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 abstract 1
HAMNKKUPIHEESI-UHFFFAOYSA-N aminoguanidine Chemical compound NNC(N)=N HAMNKKUPIHEESI-UHFFFAOYSA-N 0.000 abstract 1
APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 abstract 1
229960003942 amphotericin b Drugs 0.000 abstract 1
206010002022 amyloidosis Diseases 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Molecular Biology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PT95915254T 1994-04-13 1995-04-13 Utilizacao de inibidores da reaccao de maillard para o tratamento de doenca com base em amiloidose PT755249E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB9407305A GB2288732B (en)	1994-04-13	1994-04-13	Pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
PT755249E true PT755249E (pt)	2004-08-31

Family

ID=10753465

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT95915254T PT755249E (pt)	1994-04-13	1995-04-13	Utilizacao de inibidores da reaccao de maillard para o tratamento de doenca com base em amiloidose

Country Status (11)

Country	Link
US (2)	US5891873A (pt)
EP (1)	EP0755249B1 (pt)
JP (1)	JPH09512005A (pt)
AT (1)	ATE262895T1 (pt)
AU (1)	AU2219795A (pt)
DE (1)	DE69532804T2 (pt)
DK (1)	DK0755249T3 (pt)
ES (1)	ES2216012T3 (pt)
GB (1)	GB2288732B (pt)
PT (1)	PT755249E (pt)
WO (1)	WO1995028151A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6582728B1 (en) *	1992-07-08	2003-06-24	Inhale Therapeutic Systems, Inc.	Spray drying of macromolecules to produce inhaleable dry powders
US6673335B1 (en) *	1992-07-08	2004-01-06	Nektar Therapeutics	Compositions and methods for the pulmonary delivery of aerosolized medicaments
DK0679088T3 (da) *	1992-09-29	2002-10-28	Inhale Therapeutic Syst	Pulmonal levering af aktive fragmenter af parathyreoideaea hormon
US20030113273A1 (en) *	1996-06-17	2003-06-19	Patton John S.	Methods and compositions for pulmonary delivery of insulin
CA2183577C (en) *	1994-03-07	2007-10-30	John S. Patton	Methods and compositions for pulmonary delivery of insulin
GB2288732B (en) *	1994-04-13	1998-04-29	Quadrant Holdings Cambridge	Pharmaceutical compositions
ATE299892T1 (de) *	1994-05-18	2005-08-15	Nektar Therapeutics	Methoden und zusammensetzungen für die trockenpuderarznei aus interferonen
US6290991B1 (en)	1994-12-02	2001-09-18	Quandrant Holdings Cambridge Limited	Solid dose delivery vehicle and methods of making same
US6512010B1 (en)	1996-07-15	2003-01-28	Alza Corporation	Formulations for the administration of fluoxetine
US5780513A (en) *	1996-08-22	1998-07-14	Washington University	Method of inhibiting the release of bioactive IL-1
US6203817B1 (en)	1997-02-19	2001-03-20	Alza Corporation	Reduction of skin reactions caused by transdermal drug delivery
US20030035778A1 (en) *	1997-07-14	2003-02-20	Robert Platz	Methods and compositions for the dry powder formulation of interferon
JPH1143432A (ja) *	1997-07-25	1999-02-16	Biremo Sci:Kk	脳の老化抑制及び治療剤
US20060165606A1 (en)	1997-09-29	2006-07-27	Nektar Therapeutics	Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) *	1997-09-29	2001-10-30	Inhale Therapeutic Systems, Inc.	Stabilized preparations for use in metered dose inhalers
US6565885B1 (en)	1997-09-29	2003-05-20	Inhale Therapeutic Systems, Inc.	Methods of spray drying pharmaceutical compositions
WO1999039716A1 (en) *	1998-02-03	1999-08-12	Senju Pharmaceutical Co., Ltd.	Preventives and remedies for neuron digeneration-associated diseaseas
GB9916316D0 (en)	1999-07-12	1999-09-15	Quadrant Holdings Cambridge	Dry powder compositions
JP2003531570A (ja) *	1999-07-27	2003-10-28	アブジェニックスインク．	神経障害に関連したポリペプチド蓄積を阻害する方法および組成物
US8404217B2 (en)	2000-05-10	2013-03-26	Novartis Ag	Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en)	2000-05-10	2011-01-18	Novartis Ag	Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt)	2000-05-10	2014-12-16	Novartis Ag	Pós à base de fosfolípidos para administração de fármacos
AU2001280934A1 (en) *	2000-07-28	2002-02-13	Alliance Pharmaceutical Corp.	Methods and compositions to upregulate, redirect or limit immune responses to bioactive compounds
WO2003053411A1 (en)	2001-12-19	2003-07-03	Nektar Therapeutics	Pulmonary delivery of aminoglycosides
WO2006125207A2 (en) *	2005-05-19	2006-11-23	Amgen Inc.	Compositions and methods for increasing the stability of antibodies
CA2609980C (en) *	2005-05-27	2015-10-13	Queen's University At Kingston	Treatment of protein folding disorders
US20070031342A1 (en) *	2005-06-22	2007-02-08	Nektar Therapeutics	Sustained release microparticles for pulmonary delivery
TW200831129A (en) *	2006-10-06	2008-08-01	Amgen Inc	Stable formulations
TW200833357A (en) *	2006-10-20	2008-08-16	Amgen Inc	Stable polypeptide formulations
WO2018225623A1 (ja)	2017-06-07	2018-12-13	天野エンザイム株式会社	ラクターゼ原末及びラクターゼ製剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0325936A3 (en) *	1988-01-16	1990-01-17	Ono Pharmaceutical Co., Ltd.	Aminoguanidine derivatives and inhibitory agents on maillard reaction containing them as active ingredients
JPH03161441A (ja) *	1989-11-20	1991-07-11	Senjiyu Seiyaku Kk	メイラード反応阻害剤
JP2854631B2 (ja) *	1989-11-21	1999-02-03	千寿製薬株式会社	糖尿病合併症および老化によって引き起こされる疾患の予防・治療剤
HU218654B (hu) *	1989-11-28	2000-10-28	Syntex (U.S.A.) Inc.	Triciklusos vegyületek, ezeket hatóanyagként tartalmazó gyógyászati készítmények és eljárás előállításukra
DE69113938T2 (de) *	1990-02-19	1996-04-11	Senju Pharma Co	Zusammensetzungen von Maillard-Reaktion inhibitoren.
ATE220320T1 (de) *	1990-03-02	2002-07-15	Oregon State	Tri- und tetra-substituierte guanidine und deren verwendung als antagonisten von exzitatorischen aminosäuren
US5112596A (en) *	1990-04-23	1992-05-12	Alkermes, Inc.	Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability
ATE288262T1 (de) *	1991-02-08	2005-02-15	Scion Pharmaceuticals Inc	Substituierte guanidine und derivate hiervon als modulatoren der freisetzung von neurotransmittern und neue methode zur identifizierung von inhibitoren der neurotransmitter-freisetzung
TW221689B (pt) *	1991-08-27	1994-03-11	Otsuka Pharma Co Ltd
US5453514A (en) *	1992-12-25	1995-09-26	Yamanouchi Pharmaceutical Co., Ltd.	Pyrazole derivatives and compositions and methods of use as maillard reaction inhibitors
CA2182731A1 (en) *	1994-02-03	1995-08-10	Michael P. Vitek	Compositions and methods for advanced glycosylation endproduct-mediated modulation of amyloidosis
GB2288732B (en) *	1994-04-13	1998-04-29	Quadrant Holdings Cambridge	Pharmaceutical compositions

1994
- 1994-04-13 GB GB9407305A patent/GB2288732B/en not_active Revoked
1995
- 1995-04-13 DK DK95915254T patent/DK0755249T3/da active
- 1995-04-13 WO PCT/GB1995/000843 patent/WO1995028151A1/en not_active Ceased
- 1995-04-13 EP EP95915254A patent/EP0755249B1/en not_active Expired - Lifetime
- 1995-04-13 AU AU22197/95A patent/AU2219795A/en not_active Abandoned
- 1995-04-13 ES ES95915254T patent/ES2216012T3/es not_active Expired - Lifetime
- 1995-04-13 AT AT95915254T patent/ATE262895T1/de not_active IP Right Cessation
- 1995-04-13 DE DE69532804T patent/DE69532804T2/de not_active Expired - Fee Related
- 1995-04-13 US US08/727,597 patent/US5891873A/en not_active Expired - Lifetime
- 1995-04-13 JP JP7526804A patent/JPH09512005A/ja not_active Ceased
- 1995-04-13 PT PT95915254T patent/PT755249E/pt unknown
1998
- 1998-12-04 US US09/205,329 patent/US6034080A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH09512005A (ja)	1997-12-02
DE69532804D1 (de)	2004-05-06
DK0755249T3 (da)	2004-07-26
GB2288732A (en)	1995-11-01
GB2288732B (en)	1998-04-29
EP0755249A1 (en)	1997-01-29
DE69532804T2 (de)	2005-02-10
US5891873A (en)	1999-04-06
US6034080A (en)	2000-03-07
ATE262895T1 (de)	2004-04-15
AU2219795A (en)	1995-11-10
WO1995028151A1 (en)	1995-10-26
EP0755249B1 (en)	2004-03-31
ES2216012T3 (es)	2004-10-16
GB9407305D0 (en)	1994-06-08

Publication	Publication Date	Title
PT755249E (pt)	2004-08-31	Utilizacao de inibidores da reaccao de maillard para o tratamento de doenca com base em amiloidose
EE04221B1 (et)	2004-02-16	Östrogeeni kasutamine ravimi valmistamiseks füüsiliste seisundite raviks menopausijärgsetel isikutel
TR199701212T1 (xx)	1998-03-21	�drar� tutamama halinin tedavisi i�in alfa IL- agonistlerinin kullan�lmas�.
DK0960127T3 (da)	2010-03-29	Isoleret dimert fibroblastaktiverende protein-alfa og anvendelser deraf
TR200200068T2 (tr)	2002-05-21	Nematisital triflüorobütenler
PT1052905E (pt)	2004-06-30	Processo anti-germinativo de tuberculos e bolbos utilizando o eugenol e/ou o isoeugenol
EP0685219A3 (de)	1996-08-28	Haarbehandlungsmittel und Verfahren zur Anwendung.
BR9612283A (pt)	1999-07-13	Composição para o tratamento de manchas em peças de roupa e métodos de tratamento
ZA978639B (en)	1998-03-27	Use of 1-hydroxy-2-pyridones for the treatment of skin infections.
PL316656A1 (en)	1997-02-03	Free halophantrin base for use in treating marsh-fever and compositions containing same
TR199900505T2 (pt)	1999-06-21
FI971127A7 (fi)	1997-03-18	2,4-diaminopyrimidiini-3-oksidin tai jonkin sen suolan käyttö kollagee nin kypsymis- ja rakentumishäiriöiden hoitamiseen
MX9707642A (es)	1997-12-31	Uso de 2-oxoindol-1-carboxamidas 3-sustituidas y sus sales de base farmaceuticamente aceptables para preparar composiciones para el tratamiento y prevencion de la enfermedad de alzheimer en mamiferos, incluyendo a humanos.
ZA98420B (en)	1999-07-19	Use of pramipexole in the treatment of restless legs syndrome.
GB9916729D0 (en)	1999-09-15	Fuller for the treatment of leather,pelts and the like
NO20005548L (no)	2000-12-04	Mykobakterieinhibitorer
DE60235132D1 (de)	2010-03-11	Sojaprodukte enthaltende Zusammensetzungen
PT1052991E (pt)	2003-08-29	Utilizacao de loperamida para o tratamento de infeccoes microbianas
ES2190581T3 (es)	2003-08-01	2-aminotetralina opticamente activa, procedimiento para su preparacion y composiciones farmaceuticas que la contienen, activa en la prevencion y tratamiento de shock septico.
GB9723824D0 (en)	1998-01-07	Cytostatic agents
BR0012380A (pt)	2002-08-27	2-amino-benzoxazinonas para o tratamento de vìrus do herpes simples
SE9403861D0 (sv)	1994-11-09	Novel medicinal use
FR2786099B1 (fr)	2000-12-29	Nouvelle application therapeutique de la 1,6-dimethyl-8beta- hydroxymethyl-10alpha-methoxyergoline
IL91582A0 (en)	1990-04-29	Compositions for treating acne,for disinfecting the skin and the hair and for treating the hair
ES2181160T3 (es)	2003-02-16	Derivados de 1,4-dihidropiridina y su utilizacion en terapia.