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PT73763B - Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent - Google Patents

Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent

Info

Publication number
PT73763B
PT73763B PT7376381A PT7376381A PT73763B PT 73763 B PT73763 B PT 73763B PT 7376381 A PT7376381 A PT 7376381A PT 7376381 A PT7376381 A PT 7376381A PT 73763 B PT73763 B PT 73763B
Authority
PT
Portugal
Prior art keywords
benzofenantridine
alkaloids
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
PT7376381A
Other languages
English (en)
French (fr)
Other versions
PT73763A (fr
Original Assignee
Quatrum Empresa Nacional De Qu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quatrum Empresa Nacional De Qu filed Critical Quatrum Empresa Nacional De Qu
Priority to PT7376381A priority Critical patent/PT73763B/pt
Publication of PT73763A publication Critical patent/PT73763A/pt
Priority to GB08228066A priority patent/GB2108955B/en
Priority to DE19823236455 priority patent/DE3236455A1/de
Priority to BR8205780A priority patent/BR8205780A/pt
Priority to NL8203839A priority patent/NL8203839A/nl
Priority to IN1179/CAL/82A priority patent/IN155552B/en
Publication of PT73763B publication Critical patent/PT73763B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT7376381A 1981-10-01 1981-10-01 Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent PT73763B (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
PT7376381A PT73763B (fr) 1981-10-01 1981-10-01 Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent
GB08228066A GB2108955B (en) 1981-10-01 1982-10-01 Chemical compounds
DE19823236455 DE3236455A1 (de) 1981-10-01 1982-10-01 Epoxide von benzophenanthridinalkaloiden, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
BR8205780A BR8205780A (pt) 1981-10-01 1982-10-01 Processo para a preparacao de novos epoxidos de alcaloides-benzenofenantridinicos e processo para a preparacao de composicoes
NL8203839A NL8203839A (nl) 1981-10-01 1982-10-01 Nieuwe epoxyden van benzofenanthridine-alkaloiden, nieuwe farmaceutische preparaten die deze alkaloiden bevatten en werkwijzen voor de bereiding van zowel de nieuwe alkaloiden als de farmaceutische preparaten.
IN1179/CAL/82A IN155552B (pt) 1981-10-01 1982-10-12

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT7376381A PT73763B (fr) 1981-10-01 1981-10-01 Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
PT73763A PT73763A (fr) 1981-11-01
PT73763B true PT73763B (fr) 1983-10-26

Family

ID=20082989

Family Applications (1)

Application Number Title Priority Date Filing Date
PT7376381A PT73763B (fr) 1981-10-01 1981-10-01 Procede pour la preparation de nouveaux epoxides d'alkaloides benzofenantridiniques et de compositions pharmaceutiques qui les contiennent

Country Status (6)

Country Link
BR (1) BR8205780A (pt)
DE (1) DE3236455A1 (pt)
GB (1) GB2108955B (pt)
IN (1) IN155552B (pt)
NL (1) NL8203839A (pt)
PT (1) PT73763B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140328A (en) 1997-12-12 2000-10-31 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
US6740650B2 (en) 1999-10-29 2004-05-25 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
WO2003047505A2 (en) 2001-11-14 2003-06-12 Rutgers, The State University Topoisomerase poison agents
MXPA04004607A (es) 2001-11-14 2004-09-10 Univ Rutgers Agentes de venenos de topoisomerasa solubilizados.
EP2286812A1 (en) 2001-11-14 2011-02-23 Rutgers, The State University Solubilized topoisomerase poisons
AU2002352708A1 (en) 2001-11-14 2003-05-26 Edmond J. Lavoie Cytotoxic agents
US6992088B2 (en) 2002-08-09 2006-01-31 Rutgers, The State University Of New Jersey Nitro and amino substituted heterocycles as topoisomerase I targeting agents
AU2003265406A1 (en) 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted topoisomerase agents
WO2004014906A2 (en) 2002-08-09 2004-02-19 Rutgers, The State University Nitro and amino substituted dibenzonaphthyridines as topoisomerase agents
JP4774212B2 (ja) 2002-11-12 2011-09-14 ラトガーズ、ザ・ステイト・ユニバーシテイ・オブ・ニユー・ジヤージー トポイソメラーゼ−ターゲッティング剤
ES2401563T3 (es) 2009-03-06 2013-04-22 Rutgers, The State University Of New Jersey Derivados de metilendioxibenzo [I]fenantridina usados para tratar el cáncer
WO2010127363A1 (en) 2009-05-01 2010-11-04 Rutgers, The State University Of New Jersey Toposiomerase inhibitors
WO2017176648A1 (en) 2016-04-04 2017-10-12 Rutgers, The State University Of New Jersey Topoisomerase poisons

Also Published As

Publication number Publication date
IN155552B (pt) 1985-02-16
BR8205780A (pt) 1983-09-06
GB2108955B (en) 1985-08-21
GB2108955A (en) 1983-05-25
NL8203839A (nl) 1983-05-02
DE3236455A1 (de) 1983-05-05
PT73763A (fr) 1981-11-01

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Legal Events

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MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19950430