PT73605B - Process for preparing treatment of brain injury due to gray matter edema with indanyloxybutric acids - Google Patents
Process for preparing treatment of brain injury due to gray matter edema with indanyloxybutric acidsInfo
- Publication number
- PT73605B PT73605B PT73605A PT7360581A PT73605B PT 73605 B PT73605 B PT 73605B PT 73605 A PT73605 A PT 73605A PT 7360581 A PT7360581 A PT 7360581A PT 73605 B PT73605 B PT 73605B
- Authority
- PT
- Portugal
- Prior art keywords
- carbon atoms
- gray matter
- indanyloxybutric
- acids
- brain injury
- Prior art date
Links
- 210000004884 grey matter Anatomy 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 206010030113 Oedema Diseases 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 208000029028 brain injury Diseases 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 208000010496 Heart Arrest Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 208000032382 Ischaemic stroke Diseases 0.000 abstract 1
- 201000007981 Reye syndrome Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 208000003906 hydrocephalus Diseases 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000029058 respiratory gaseous exchange Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18354680A | 1980-09-02 | 1980-09-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT73605A PT73605A (en) | 1981-10-01 |
| PT73605B true PT73605B (en) | 1983-09-01 |
Family
ID=22673265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT73605A PT73605B (en) | 1980-09-02 | 1981-09-01 | Process for preparing treatment of brain injury due to gray matter edema with indanyloxybutric acids |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0047011B1 (pt) |
| JP (1) | JPS57145832A (pt) |
| AT (1) | ATE13877T1 (pt) |
| DE (1) | DE3171029D1 (pt) |
| DK (1) | DK386581A (pt) |
| ES (1) | ES8303278A1 (pt) |
| GR (1) | GR75754B (pt) |
| IE (1) | IE51535B1 (pt) |
| PT (1) | PT73605B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61103850A (ja) * | 1984-10-29 | 1986-05-22 | Ono Pharmaceut Co Ltd | ３−（インダン−５−イルオキシ（またはチオ））シクロペンタンカルボン酸誘導体、それらの製造方法及びそれらを有効成分として含有する治療剤 |
| JPS6219552A (ja) | 1985-07-19 | 1987-01-28 | Ono Pharmaceut Co Ltd | ３−〔（４−アロイル）フエノキシ（またはフエニルチオ）〕シクロペンタンカルボン酸誘導体、それらの製造方法及びそれらを有効成分として含有する脳浮腫治療剤 |
| US12059403B2 (en) | 2016-08-04 | 2024-08-13 | University Of Iowa Research Foundation | Use of SWELL1 inhibitors and modulators to treat type 2 diabetes and obesity |
| EP3979998A4 (en) * | 2019-06-10 | 2023-07-19 | Washington University | Swell1-lrrc8 complex modulators |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3984465A (en) * | 1972-10-13 | 1976-10-05 | Merck & Co., Inc. | 1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids |
| NL187854C (nl) * | 1973-10-11 | 1992-02-03 | Merck & Co Inc | Werkwijze ter bereiding van farmaceutische preparaten met diuretische en saluretische werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte op plaats 2 gesubstitueerde 1-oxo-5-indanyloxy-(of -thio-)-alkaanzuren. |
| US4012524A (en) * | 1973-10-12 | 1977-03-15 | Merck & Co., Inc. | [1-Hydroxy-5-indanyloxy (or thio)]-alkanoic acids |
-
1981
- 1981-08-24 IE IE1935/81A patent/IE51535B1/en unknown
- 1981-08-31 GR GR65914A patent/GR75754B/el unknown
- 1981-09-01 ES ES505115A patent/ES8303278A1/es not_active Expired
- 1981-09-01 PT PT73605A patent/PT73605B/pt unknown
- 1981-09-01 DK DK386581A patent/DK386581A/da not_active Application Discontinuation
- 1981-09-01 AT AT81106827T patent/ATE13877T1/de not_active IP Right Cessation
- 1981-09-01 EP EP81106827A patent/EP0047011B1/en not_active Expired
- 1981-09-01 DE DE8181106827T patent/DE3171029D1/de not_active Expired
- 1981-09-02 JP JP56137108A patent/JPS57145832A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK386581A (da) | 1982-03-03 |
| GR75754B (pt) | 1984-08-02 |
| ATE13877T1 (de) | 1985-07-15 |
| ES505115A0 (es) | 1982-12-16 |
| IE51535B1 (en) | 1987-01-07 |
| EP0047011A1 (en) | 1982-03-10 |
| PT73605A (en) | 1981-10-01 |
| JPS57145832A (en) | 1982-09-09 |
| ES8303278A1 (es) | 1983-02-16 |
| DE3171029D1 (en) | 1985-07-25 |
| EP0047011B1 (en) | 1985-06-19 |
| IE811935L (en) | 1982-03-02 |
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