PT728147E - Peptideos natriureticos auriculares especificos dereceptor - Google Patents
Peptideos natriureticos auriculares especificos dereceptorInfo
- Publication number
- PT728147E PT728147E PT95901112T PT95901112T PT728147E PT 728147 E PT728147 E PT 728147E PT 95901112 T PT95901112 T PT 95901112T PT 95901112 T PT95901112 T PT 95901112T PT 728147 E PT728147 E PT 728147E
- Authority
- PT
- Portugal
- Prior art keywords
- human
- receptor
- dereceptor
- headphones
- peptide specific
- Prior art date
Links
- 235000016709 nutrition Nutrition 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 239000002934 diuretic Substances 0.000 abstract 2
- 208000009304 Acute Kidney Injury Diseases 0.000 abstract 1
- 102000002723 Atrial Natriuretic Factor Human genes 0.000 abstract 1
- 101800001288 Atrial natriuretic factor Proteins 0.000 abstract 1
- 101800001890 Atrial natriuretic peptide Proteins 0.000 abstract 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 208000033626 Renal failure acute Diseases 0.000 abstract 1
- 201000011040 acute kidney failure Diseases 0.000 abstract 1
- NSQLIUXCMFBZME-MPVJKSABSA-N carperitide Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)=O)[C@@H](C)CC)C1=CC=CC=C1 NSQLIUXCMFBZME-MPVJKSABSA-N 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 230000001452 natriuretic effect Effects 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 206010038464 renal hypertension Diseases 0.000 abstract 1
- 102220005466 rs35816645 Human genes 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 230000002883 vasorelaxation effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15299493A | 1993-11-12 | 1993-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT728147E true PT728147E (pt) | 2003-06-30 |
Family
ID=22545344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT95901112T PT728147E (pt) | 1993-11-12 | 1994-11-04 | Peptideos natriureticos auriculares especificos dereceptor |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0728147B1 (pt) |
| JP (1) | JP3989535B2 (pt) |
| AT (1) | ATE232545T1 (pt) |
| AU (1) | AU1934995A (pt) |
| CA (1) | CA2174517C (pt) |
| DE (1) | DE69432123T2 (pt) |
| DK (1) | DK0728147T3 (pt) |
| ES (1) | ES2194895T3 (pt) |
| PT (1) | PT728147E (pt) |
| WO (1) | WO1995013296A1 (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6028055A (en) * | 1996-10-22 | 2000-02-22 | Genetech, Inc. | Receptor selective BNP |
| AU4816497A (en) * | 1996-10-22 | 1998-05-15 | Genentech Inc. | Receptor specific brain natriuretic peptide (bnp) |
| AU6820898A (en) * | 1997-04-04 | 1998-10-30 | Novo Nordisk A/S | Natriuretic peptide derivatives |
| US6013630A (en) | 1997-08-21 | 2000-01-11 | Curagen Corporation | Atrial natriuretic factor mutants and ischemic stroke |
| PL2348114T3 (pl) | 2004-04-21 | 2019-08-30 | Alexion Pharmaceuticals, Inc. | Koniugaty do dostarczania do kości i sposób ich wykorzystania do nakierowywania białek na kość |
| EP2004633A4 (en) | 2006-03-30 | 2009-08-26 | Palatin Technologies Inc | LINEAR NATRIURETIC PEPTIDE CONSTRUCTS |
| US8580746B2 (en) | 2006-03-30 | 2013-11-12 | Palatin Technologies, Inc. | Amide linkage cyclic natriuretic peptide constructs |
| KR101434612B1 (ko) | 2006-03-30 | 2014-08-26 | 팔라틴 테크놀로지스 인코포레이티드 | 사이클릭 나트륨 이뇨 펩타이드 구조물 |
| EP2658979B1 (en) | 2010-12-27 | 2018-02-14 | Alexion Pharmaceuticals, Inc. | Compositions comprising natriuretic peptides and methods of use thereof |
| US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
| US10822596B2 (en) | 2014-07-11 | 2020-11-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for treating craniosynostosis |
| MX389350B (es) | 2014-12-05 | 2025-03-19 | Alexion Pharma Inc | Fosfatasas alcalinas recombinantes y usos de las mismas para el tratamiento de convulsiones. |
| US10603361B2 (en) | 2015-01-28 | 2020-03-31 | Alexion Pharmaceuticals, Inc. | Methods of treating a subject with an alkaline phosphatase deficiency |
| KR102644116B1 (ko) | 2015-08-17 | 2024-03-05 | 알렉시온 파마슈티칼스, 인코포레이티드 | 알칼린 포스파타제의 제조 |
| WO2017058822A1 (en) | 2015-09-28 | 2017-04-06 | Alexion Pharmaceuticals, Inc. | Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia |
| JP2018533571A (ja) | 2015-10-30 | 2018-11-15 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 患者の頭蓋縫合早期癒合症を治療するための方法 |
| WO2017155569A1 (en) | 2016-03-08 | 2017-09-14 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
| CA3019726A1 (en) | 2016-04-01 | 2017-10-05 | Alexion Pharmaceuticals, Inc. | Treating muscle weakness with alkaline phosphatases |
| EP3436020A4 (en) | 2016-04-01 | 2019-12-25 | Alexion Pharmaceuticals, Inc. | METHOD FOR TREATING HYPOPHOSPHATASIE IN TEENS AND ADULTS |
| EP3464573A4 (en) | 2016-06-06 | 2020-02-19 | Alexion Pharmaceuticals, Inc. | EFFECTS OF METALS ON THE PRODUCTION OF ALKALINE PHOSPHATASES |
| WO2018035420A1 (en) | 2016-08-18 | 2018-02-22 | Alexion Pharmaceuticals, Inc. | Methods for treating tracheobronchomalacia |
| JP2020512363A (ja) | 2017-03-31 | 2020-04-23 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 成人及び青年における低ホスファターゼ症(hpp)を治療する方法 |
| US11913039B2 (en) | 2018-03-30 | 2024-02-27 | Alexion Pharmaceuticals, Inc. | Method for producing recombinant alkaline phosphatase |
| US12268733B2 (en) | 2018-08-10 | 2025-04-08 | Alexion Pharmaceuticals, Inc. | Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase |
| JP2023504208A (ja) | 2019-12-09 | 2023-02-01 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | アルカリホスファターゼポリペプチド及びその使用方法 |
| US12083169B2 (en) | 2021-02-12 | 2024-09-10 | Alexion Pharmaceuticals, Inc. | Alkaline phosphatase polypeptides and methods of use thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4211989A (en) * | 1988-08-18 | 1990-03-23 | California Biotechnology, Inc. | Atrial natriuretic peptide clearance inhibitors |
| EP0465097A3 (en) * | 1990-06-26 | 1993-03-24 | Merck & Co. Inc. | Peptides having atrial natriuretic factor activity |
-
1994
- 1994-11-04 WO PCT/US1994/012591 patent/WO1995013296A1/en not_active Ceased
- 1994-11-04 AT AT95901112T patent/ATE232545T1/de active
- 1994-11-04 ES ES95901112T patent/ES2194895T3/es not_active Expired - Lifetime
- 1994-11-04 DK DK95901112T patent/DK0728147T3/da active
- 1994-11-04 EP EP95901112A patent/EP0728147B1/en not_active Expired - Lifetime
- 1994-11-04 JP JP51387895A patent/JP3989535B2/ja not_active Expired - Fee Related
- 1994-11-04 CA CA002174517A patent/CA2174517C/en not_active Expired - Lifetime
- 1994-11-04 DE DE69432123T patent/DE69432123T2/de not_active Expired - Lifetime
- 1994-11-04 AU AU19349/95A patent/AU1934995A/en not_active Abandoned
- 1994-11-04 PT PT95901112T patent/PT728147E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69432123T2 (de) | 2004-01-08 |
| JPH09505049A (ja) | 1997-05-20 |
| WO1995013296A1 (en) | 1995-05-18 |
| AU1934995A (en) | 1995-05-29 |
| ES2194895T3 (es) | 2003-12-01 |
| EP0728147A1 (en) | 1996-08-28 |
| CA2174517A1 (en) | 1995-05-18 |
| CA2174517C (en) | 2007-01-02 |
| JP3989535B2 (ja) | 2007-10-10 |
| DK0728147T3 (da) | 2003-06-10 |
| ATE232545T1 (de) | 2003-02-15 |
| DE69432123D1 (de) | 2003-03-20 |
| EP0728147B1 (en) | 2003-02-12 |
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