PT3725791T - Sal que serve como inibidor de akt e seu cristal - Google Patents
Sal que serve como inibidor de akt e seu cristalInfo
- Publication number
- PT3725791T PT3725791T PT188877179T PT18887717T PT3725791T PT 3725791 T PT3725791 T PT 3725791T PT 188877179 T PT188877179 T PT 188877179T PT 18887717 T PT18887717 T PT 18887717T PT 3725791 T PT3725791 T PT 3725791T
- Authority
- PT
- Portugal
- Prior art keywords
- crystal
- akt inhibitor
- salt serving
- serving
- salt
- Prior art date
Links
- 229940126638 Akt inhibitor Drugs 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
- 239000003197 protein kinase B inhibitor Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711331448 | 2017-12-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3725791T true PT3725791T (pt) | 2023-04-04 |
Family
ID=66819227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT188877179T PT3725791T (pt) | 2017-12-13 | 2018-12-12 | Sal que serve como inibidor de akt e seu cristal |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11261196B2 (pt) |
| EP (1) | EP3725791B1 (pt) |
| JP (1) | JP7101781B2 (pt) |
| KR (1) | KR102394934B1 (pt) |
| CN (1) | CN111433213B (pt) |
| ES (1) | ES2943092T3 (pt) |
| PT (1) | PT3725791T (pt) |
| WO (1) | WO2019114741A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3186565A1 (en) * | 2020-07-22 | 2022-01-27 | Lei Miao | Unit dosage composition of akt inhibitor |
| JP7472391B2 (ja) * | 2020-07-22 | 2024-04-22 | 南京正大天晴制薬有限公司 | ジヒドロピリド［２，３－ｄ］ピリミジノン誘導体の塩及び結晶形 |
| CN116583525A (zh) * | 2020-12-07 | 2023-08-11 | 南京正大天晴制药有限公司 | 一种吡唑并氮杂卓类akt抑制剂 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6887864B2 (en) * | 2002-03-12 | 2005-05-03 | Hoffmann-La Roche Inc. | Azepane derivatives |
| WO2007076423A2 (en) * | 2005-12-22 | 2007-07-05 | Smithkline Beecham Corporation | INHIBITORS OF Akt ACTIVITY |
| US8207180B2 (en) * | 2006-11-28 | 2012-06-26 | Nerviano Medical Sciences S.R.L. | Tricyclic indoles and (4,5-dihydro) indoles |
| UY30892A1 (es) | 2007-02-07 | 2008-09-02 | Smithkline Beckman Corp | Inhibidores de la actividad akt |
| DE602008003055D1 (de) * | 2007-05-31 | 2010-12-02 | Nerviano Medical Sciences Srl | Zyklokondensierte Azaindole, die als Kinase-Hemmer wirken |
| EP2306825A4 (en) | 2008-06-26 | 2011-12-28 | Glaxosmithkline Llc | HAMMER OF ACT ACTIVITY |
| EP3473628B1 (en) * | 2016-06-16 | 2019-12-11 | Harbin Zhenbao Pharmaceutical Co., Ltd. | Dihydropyrazole azepine compound serving as akt inhibitor |
-
2018
- 2018-12-12 ES ES18887717T patent/ES2943092T3/es active Active
- 2018-12-12 EP EP18887717.9A patent/EP3725791B1/en active Active
- 2018-12-12 JP JP2020532703A patent/JP7101781B2/ja active Active
- 2018-12-12 US US16/772,322 patent/US11261196B2/en active Active
- 2018-12-12 CN CN201880078387.9A patent/CN111433213B/zh active Active
- 2018-12-12 WO PCT/CN2018/120531 patent/WO2019114741A1/zh not_active Ceased
- 2018-12-12 KR KR1020207020007A patent/KR102394934B1/ko active Active
- 2018-12-12 PT PT188877179T patent/PT3725791T/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20210087205A1 (en) | 2021-03-25 |
| CN111433213A (zh) | 2020-07-17 |
| KR102394934B1 (ko) | 2022-05-04 |
| CN111433213B (zh) | 2023-03-10 |
| ES2943092T3 (es) | 2023-06-08 |
| EP3725791B1 (en) | 2023-03-15 |
| US11261196B2 (en) | 2022-03-01 |
| EP3725791A1 (en) | 2020-10-21 |
| JP2021508319A (ja) | 2021-03-04 |
| KR20200097771A (ko) | 2020-08-19 |
| WO2019114741A1 (zh) | 2019-06-20 |
| JP7101781B2 (ja) | 2022-07-15 |
| EP3725791A4 (en) | 2020-11-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3658557A4 (en) | TYK2 INHIBITORS AND USES THEREOF | |
| IL270330B (en) | Beta-lactamase inhibitors and their uses | |
| EP3344624B8 (en) | Tyk2 inhibitors and uses thereof | |
| EP3268369A4 (en) | Anti-alphavbeta1 integrin inhibitors and methods of use | |
| EP3134091A4 (en) | Irak inhibitors and uses thereof | |
| EP3262049A4 (en) | Tyk2 inhibitors and uses thereof | |
| GB201605126D0 (en) | Inhibitors and their uses | |
| EP3681499A4 (en) | CONNECTIONS AS RAS INHIBITORS AND THEIR USE | |
| EP3281942A4 (en) | B-lactamase inhibitor and application thereof | |
| EP3336090A4 (en) | INHIBITOR OF IRAQ4 AND ITS USE | |
| PT3621694T (pt) | Inibidores de lrrc33 e sua utilização | |
| PT3532459T (pt) | Inibidores de lsd1 e seus usos médicos | |
| PL3447056T3 (pl) | Związek będący inhibitorem wielu kinaz oraz jego postać krystaliczna i zastosowanie | |
| EP3555051A4 (en) | HEPARANASE INHIBITORS AND USE THEREOF | |
| IL254916A0 (en) | Inhibitors and their uses | |
| IL262400A (en) | Erbb inhibitors and uses thereof | |
| EP3731840A4 (en) | NADPH OXIDASE INHIBITORS AND THEIR USE | |
| PT3725791T (pt) | Sal que serve como inibidor de akt e seu cristal | |
| EP3573611A4 (en) | AMIDE COMPOUNDS AND USES THEREOF | |
| EP3524254A4 (en) | LIN28A ACTIVATOR AND USE OF IT | |
| EP3269710A4 (en) | Nintedanib diethanesulfonate salt crystal and preparation method and use thereof | |
| EP3555071A4 (en) | HEPARANASE INHIBITORS AND THEIR USE | |
| HK40029662A (en) | Novel salts and crystals | |
| ZA201901155B (en) | Salt and crystal of diaza-benzofluorane compound | |
| HK40036520A (en) | Dopamine-b-hydroxylase inhibitors |