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PT3294904T - Methods for assesing the purity of a mesenchymal stem cells preparation - Google Patents

Methods for assesing the purity of a mesenchymal stem cells preparation

Info

Publication number
PT3294904T
PT3294904T PT167230622T PT16723062T PT3294904T PT 3294904 T PT3294904 T PT 3294904T PT 167230622 T PT167230622 T PT 167230622T PT 16723062 T PT16723062 T PT 16723062T PT 3294904 T PT3294904 T PT 3294904T
Authority
PT
Portugal
Prior art keywords
assesing
purity
methods
stem cells
mesenchymal stem
Prior art date
Application number
PT167230622T
Other languages
Portuguese (pt)
Original Assignee
Univ Catholique Louvain
Cliniques Univ Saint Luc
Novadip Biosciences Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Catholique Louvain, Cliniques Univ Saint Luc, Novadip Biosciences Sa filed Critical Univ Catholique Louvain
Publication of PT3294904T publication Critical patent/PT3294904T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PT167230622T 2015-05-08 2016-05-09 Methods for assesing the purity of a mesenchymal stem cells preparation PT3294904T (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562158875P 2015-05-08 2015-05-08

Publications (1)

Publication Number Publication Date
PT3294904T true PT3294904T (en) 2021-10-14

Family

ID=53776427

Family Applications (1)

Application Number Title Priority Date Filing Date
PT167230622T PT3294904T (en) 2015-05-08 2016-05-09 Methods for assesing the purity of a mesenchymal stem cells preparation

Country Status (15)

Country Link
US (2) US11203785B2 (en)
EP (2) EP3091084A1 (en)
JP (2) JP6727291B2 (en)
KR (1) KR20180002760A (en)
CN (1) CN107709575B (en)
AU (1) AU2016259736B2 (en)
CA (1) CA2985268A1 (en)
DK (1) DK3294904T3 (en)
ES (1) ES2892487T3 (en)
IL (1) IL255500B (en)
MX (1) MX389029B (en)
PT (1) PT3294904T (en)
RU (1) RU2738969C2 (en)
WO (1) WO2016180788A1 (en)
ZA (1) ZA201707477B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3012128T3 (en) * 2017-09-29 2025-04-08 Pharmabio Corp Quality management method for regeneration medical product or the like by using standardized expression amount
PL241520B1 (en) * 2020-03-27 2022-10-17 Polski Bank Komorek Macierzystych Spolka Akcyjna Application of the gene panel to determine the teratogenic potential of mesenchymal and perinatal cells
CN112159794B (en) * 2020-09-17 2022-07-15 中国人民解放军空军军医大学 Preparation and application of CD166+ subset of bone-related mesenchymal stem cells
US20230365937A1 (en) * 2020-10-26 2023-11-16 Hadasit Medical Research Services And Development Ltd. Mesenchymal stem cells and their culture
WO2022139442A1 (en) * 2020-12-22 2022-06-30 주식회사 셀투인 Marker for selecting high-quality stem cells, and method for selecting high-quality stem cells using same
EP4408979A1 (en) * 2021-09-30 2024-08-07 Polski Bank Komórek Macierzystych S.A. Expression analysis of a specific gene pool to determine whether the population of adipose tissue-derived mesenchymal cells (at-msc) selected for clinical application can undergo a transformation into neoplastic cells
WO2025144762A1 (en) * 2023-12-28 2025-07-03 Immorta Bio, Inc. Reprogrammed cell modulation of cancer microenvironment by tumor homing personalized regenerative cells
CN118048446B (en) * 2024-03-21 2025-05-16 杭州凤喆凰生物科技有限公司 One-step double RT-Q-PCR method for analyzing biological activity and stability of mesenchymal stem cell product, primer and TaqMan probe

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049139A1 (en) 2000-03-23 2001-12-06 Eric Lagasse Hepatic regeneration from hematopoietic stem cells
ES2325715B1 (en) * 2007-08-03 2010-06-17 Genetrix, S.L. POPULATION OF ADULT MOTHER CELLS DERIVED FROM CARDIAC ADIPOSE TISSUE AND ITS USE IN CARDIAC REGENERATION.
JP5416895B2 (en) * 2007-10-23 2014-02-12 学校法人慶應義塾 Efficient production of monocyte-derived pluripotent cells (MOMC)
ES2351916B8 (en) * 2009-07-30 2012-07-09 Centro Nacional De Investigaciones Cardiovasculares (Cnic) METHOD OF IDENTIFICATION OF SENESCENT MOTHER MESENQUIMAL CELLS
CN103200937B (en) 2010-09-01 2020-07-03 托马斯杰弗逊大学 Compositions and methods for muscle repair and regeneration
ES2675693T3 (en) * 2011-07-06 2018-07-11 Cell Therapy Limited Mesodermal lineage progenitor cells
KR101751355B1 (en) * 2011-08-24 2017-07-04 (주)아모레퍼시픽 Adult stem cells derived human skin dermis
US20130251670A1 (en) * 2011-09-13 2013-09-26 Aidan Products, Inc Treatment of Macular Edema Utilizing Stem Cell and Conditioned Media Thereof
BR112014017320A2 (en) * 2012-01-13 2018-05-29 Genentech Inc method for determining whether a patient is prone to respond to treatment with a vegf antagonist, method for optimizing the therapeutic efficacy of a vegf antagonist, method for selecting a therapy, method for identifying a biomarker, and method for diagnosing an angiogenic disorder
JP6198199B2 (en) * 2013-03-12 2017-09-20 美智代 津留 Method for producing parallel fibrous connective tissue
WO2014144392A1 (en) 2013-03-15 2014-09-18 Turner Designs Hydrocarbon Instruments, Inc. Solvent-free method for measuring hydrocarbons in water
JP5889856B2 (en) 2013-10-15 2016-03-22 佛教慈濟醫療財團法人 Method for proliferating human mesenchymal stem cells ex vivo, adjuvant used therefor, method for extracting growth factor of human mesenchymal stem cells ex vivo, and use of the growth factor

Also Published As

Publication number Publication date
EP3294904A1 (en) 2018-03-21
MX389029B (en) 2025-03-20
JP6967122B2 (en) 2021-11-17
CA2985268A1 (en) 2016-11-17
ES2892487T3 (en) 2022-02-04
US20220064729A1 (en) 2022-03-03
WO2016180788A1 (en) 2016-11-17
ZA201707477B (en) 2020-05-27
CN107709575B (en) 2022-11-15
IL255500B (en) 2021-04-29
HK1251620A1 (en) 2019-02-01
CN107709575A (en) 2018-02-16
MX2017014247A (en) 2018-06-28
JP2018522251A (en) 2018-08-09
RU2017139097A (en) 2019-06-10
US11203785B2 (en) 2021-12-21
JP2020173265A (en) 2020-10-22
DK3294904T3 (en) 2021-10-11
BR112017024011A2 (en) 2018-07-17
EP3294904B1 (en) 2021-08-18
KR20180002760A (en) 2018-01-08
EP3091084A1 (en) 2016-11-09
RU2738969C2 (en) 2020-12-21
US20180135124A1 (en) 2018-05-17
RU2017139097A3 (en) 2019-08-30
IL255500A (en) 2018-01-31
AU2016259736B2 (en) 2022-06-16
JP6727291B2 (en) 2020-07-22
AU2016259736A1 (en) 2017-11-30

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