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PT3038654T - Nova utilização - Google Patents

Nova utilização

Info

Publication number
PT3038654T
PT3038654T PT147617021T PT14761702T PT3038654T PT 3038654 T PT3038654 T PT 3038654T PT 147617021 T PT147617021 T PT 147617021T PT 14761702 T PT14761702 T PT 14761702T PT 3038654 T PT3038654 T PT 3038654T
Authority
PT
Portugal
Prior art keywords
new use
new
Prior art date
Application number
PT147617021T
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51494327&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3038654(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2013/056680 external-priority patent/WO2015030711A1/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT3038654T publication Critical patent/PT3038654T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • A61K9/2826Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
PT147617021T 2013-08-26 2014-08-26 Nova utilização PT3038654T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US2013/056680 WO2015030711A1 (en) 2013-08-26 2013-08-26 New use
US201461972933P 2014-03-31 2014-03-31

Publications (1)

Publication Number Publication Date
PT3038654T true PT3038654T (pt) 2020-02-04

Family

ID=51494327

Family Applications (3)

Application Number Title Priority Date Filing Date
PT147617021T PT3038654T (pt) 2013-08-26 2014-08-26 Nova utilização
PT232021907T PT4321157T (pt) 2013-08-26 2014-08-26 Nova utilização de uma combinação de um bloqueador dos recetores da angiotensina (arb) com um inibidor da endopeptidase neutra (nepi)
PT192028546T PT3626270T (pt) 2013-08-26 2014-08-26 Tratamento de doenças cardiovasculares

Family Applications After (2)

Application Number Title Priority Date Filing Date
PT232021907T PT4321157T (pt) 2013-08-26 2014-08-26 Nova utilização de uma combinação de um bloqueador dos recetores da angiotensina (arb) com um inibidor da endopeptidase neutra (nepi)
PT192028546T PT3626270T (pt) 2013-08-26 2014-08-26 Tratamento de doenças cardiovasculares

Country Status (16)

Country Link
US (2) US20160213646A1 (pt)
EP (4) EP3038654B1 (pt)
JP (1) JP6097888B2 (pt)
CY (1) CY1122531T1 (pt)
DK (3) DK3626270T3 (pt)
ES (3) ES3001196T3 (pt)
FI (2) FI4321157T3 (pt)
HR (3) HRP20241763T1 (pt)
HU (3) HUE047186T2 (pt)
LT (3) LT3038654T (pt)
PL (3) PL3626270T3 (pt)
PT (3) PT3038654T (pt)
RS (3) RS65037B1 (pt)
SI (3) SI3626270T1 (pt)
SM (1) SMT202500001T1 (pt)
WO (1) WO2015028941A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE047186T2 (hu) 2013-08-26 2020-04-28 Novartis Ag Új alkalmazás
EP3253740A1 (en) * 2015-02-06 2017-12-13 Mylan Laboratories Ltd. Amorphous trisodium sacubitril valsartan and a process for the preparation thereof
US20180140579A1 (en) * 2015-05-29 2018-05-24 Novartis Ag Sacubitril and valsartan for treating metabolic disease
CN106309388A (zh) * 2015-06-30 2017-01-11 深圳信立泰药业股份有限公司 一种用于心衰治疗的药物组合物及其制备方法
WO2017036420A1 (zh) * 2015-09-06 2017-03-09 常州方楠医药技术有限公司 含沙库比曲和缬沙坦的药用组合物及其制备方法
CN106491600A (zh) * 2015-09-06 2017-03-15 常州方楠医药技术有限公司 无定型沙库区比、缬沙坦或其药学上可接受的盐与药用辅料的组合物及其制备方法
CN107510653A (zh) * 2016-06-17 2017-12-26 常州爱诺新睿医药技术有限公司 一种含有无定型沙库比曲和缬沙坦的固体分散体的药用组合物及其制备方法
WO2017042700A1 (en) * 2015-09-07 2017-03-16 Sun Pharmaceutical Industries Limited Solid forms of valsartan and sacubitril
WO2017063581A1 (zh) * 2015-10-16 2017-04-20 深圳信立泰药业股份有限公司 一种用于心血管疾病治疗的口服制剂及其制备方法
CN105330609B (zh) * 2015-12-07 2017-12-22 南京正大天晴制药有限公司 一种制备lcz696的方法
EP3411018A1 (en) 2016-02-03 2018-12-12 Novartis AG Galenic formulations of organic compounds
CN106176681A (zh) * 2016-08-25 2016-12-07 泰力特医药(湖北)有限公司 一种抗心脏衰竭药物lcz696口服缓释微丸及其制备方法
US11382866B2 (en) 2017-07-06 2022-07-12 Mankind Pharma Ltd. Fixed dose pharmaceutical composition of valsartan and sacubitril
WO2020039386A1 (en) 2018-08-23 2020-02-27 Novartis Ag New pharmaceutical use for the treatment of heart failure
WO2020039394A1 (en) 2018-08-24 2020-02-27 Novartis Ag New drug combinations
JP7316449B2 (ja) * 2019-09-20 2023-07-27 シェンヅェン サルブリス ファーマシューティカルズ カンパニー リミテッド 心不全治療におけるアンジオテンシンii受容体アンタゴニスト代謝産物とnep阻害剤との複合体の使用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97219A (en) 1990-02-19 1995-12-08 Ciba Geigy Ag Biphenyl substituted aliphatic amino compounds process for their preparation and pharmaceutical compositions containing them
US5217996A (en) 1992-01-22 1993-06-08 Ciba-Geigy Corporation Biaryl substituted 4-amino-butyric acid amides
CN1249682A (zh) * 1997-01-10 2000-04-05 麦克公司 用于治疗有症状的心力哀竭的血管紧张素ⅱ拮抗剂
ES2290429T3 (es) 2002-01-17 2008-02-16 Novartis Ag Composiciones farmaceuticas que comprenden valsartan e inhibidores de nep.
AU2004238546A1 (en) * 2003-05-16 2004-11-25 Novartis Ag Pharmaceutical composition comprising valsartan
AR057882A1 (es) * 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
WO2009061713A1 (en) 2007-11-06 2009-05-14 Novartis Ag Dual-acting pharmaceutical compositions based on superstructures of angiotensin receptor antagonist/blocker (arb) and neutral endopeptidase (nep) inhibitor
KR20170015525A (ko) 2008-11-22 2017-02-08 제넨테크, 인크. 유방암의 치료를 위한, 화학요법과 조합된 항-vegf 항체의 용도
EP2608784B1 (en) * 2010-08-24 2018-09-19 Novartis AG Treatment or prevention of heart failure in a mammal receiving anti-coagulant therapy
EP3943084A1 (en) 2012-08-24 2022-01-26 Novartis AG Nep inhibitors for treating diseases characterized by atrial enlargement or remodeling
HUE047186T2 (hu) 2013-08-26 2020-04-28 Novartis Ag Új alkalmazás
WO2015030711A1 (en) * 2013-08-26 2015-03-05 Novartis Ag New use

Also Published As

Publication number Publication date
EP3626270B1 (en) 2023-10-11
EP4321157A2 (en) 2024-02-14
RS65037B1 (sr) 2024-02-29
FI3626270T3 (fi) 2024-01-11
DK3626270T3 (da) 2024-01-15
PL3626270T3 (pl) 2024-04-08
DK4321157T3 (da) 2024-12-16
RS66371B1 (sr) 2025-02-28
SI3626270T1 (sl) 2024-03-29
ES2767084T3 (es) 2020-06-16
EP3038654B1 (en) 2019-10-30
ES2968541T3 (es) 2024-05-10
EP4512397A2 (en) 2025-02-26
ES3001196T3 (es) 2025-03-04
PL3038654T3 (pl) 2020-05-18
PL4321157T3 (pl) 2025-03-03
HUE069419T2 (hu) 2025-03-28
LT3626270T (lt) 2024-01-25
RS59816B1 (sr) 2020-02-28
CY1122531T1 (el) 2021-01-27
PT3626270T (pt) 2024-01-11
WO2015028941A1 (en) 2015-03-05
HRP20240034T1 (hr) 2024-03-29
SMT202500001T1 (it) 2025-03-12
DK3038654T3 (da) 2020-02-03
EP4512397A3 (en) 2025-05-14
HRP20241763T1 (hr) 2025-03-14
PT4321157T (pt) 2025-01-08
EP3626270A1 (en) 2020-03-25
FI4321157T3 (fi) 2025-01-20
HUE064634T2 (hu) 2024-04-28
EP4321157B1 (en) 2024-10-23
HRP20200060T1 (hr) 2020-04-03
US20210077461A1 (en) 2021-03-18
JP6097888B2 (ja) 2017-03-15
EP4321157A3 (en) 2024-05-15
US20160213646A1 (en) 2016-07-28
SI4321157T1 (sl) 2025-03-31
HUE047186T2 (hu) 2020-04-28
LT4321157T (lt) 2025-01-10
LT3038654T (lt) 2020-01-27
SI3038654T1 (sl) 2020-02-28
EP3038654A1 (en) 2016-07-06
JP2016528303A (ja) 2016-09-15

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