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PT2680873T - Agentes antifúngicos e suas utilizações - Google Patents

Agentes antifúngicos e suas utilizações

Info

Publication number
PT2680873T
PT2680873T PT127519940T PT12751994T PT2680873T PT 2680873 T PT2680873 T PT 2680873T PT 127519940 T PT127519940 T PT 127519940T PT 12751994 T PT12751994 T PT 12751994T PT 2680873 T PT2680873 T PT 2680873T
Authority
PT
Portugal
Prior art keywords
antifungal agents
antifungal
agents
Prior art date
Application number
PT127519940T
Other languages
English (en)
Inventor
Duke James Kenneth Jr
Patrick Laudeman Christopher
Balkrishna Malkar Navdeep
Radhakrishnan Balasingham
Original Assignee
Cidara Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cidara Therapeutics Inc filed Critical Cidara Therapeutics Inc
Publication of PT2680873T publication Critical patent/PT2680873T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT127519940T 2011-03-03 2012-03-02 Agentes antifúngicos e suas utilizações PT2680873T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161448807P 2011-03-03 2011-03-03

Publications (1)

Publication Number Publication Date
PT2680873T true PT2680873T (pt) 2017-11-01

Family

ID=46758514

Family Applications (1)

Application Number Title Priority Date Filing Date
PT127519940T PT2680873T (pt) 2011-03-03 2012-03-02 Agentes antifúngicos e suas utilizações

Country Status (21)

Country Link
US (6) US8722619B2 (pt)
EP (2) EP3192803B1 (pt)
JP (4) JP5809296B2 (pt)
CN (2) CN106279369B (pt)
CA (2) CA2865791C (pt)
CY (2) CY1119709T1 (pt)
DK (1) DK2680873T3 (pt)
ES (1) ES2645074T3 (pt)
FI (1) FIC20240022I1 (pt)
FR (1) FR24C1027I2 (pt)
HR (1) HRP20171579T8 (pt)
HU (2) HUE036778T2 (pt)
LT (2) LT2680873T (pt)
NL (1) NL301280I2 (pt)
NO (1) NO2680873T3 (pt)
PL (1) PL2680873T3 (pt)
PT (1) PT2680873T (pt)
RS (1) RS56426B1 (pt)
SI (1) SI2680873T1 (pt)
SM (1) SMT201700460T1 (pt)
WO (1) WO2012119065A2 (pt)

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PL3677252T3 (pl) * 2012-03-19 2024-01-08 Cidara Therapeutics, Inc. Schematy dawkowania dla związków z klasy echinokandyn
WO2015035102A2 (en) * 2013-09-04 2015-03-12 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
EP3136864A4 (en) * 2014-04-28 2017-12-27 University of Central Florida Research Foundation, Inc. Compositions, methods of making a composition, and methods of use
WO2016201283A1 (en) * 2015-06-12 2016-12-15 Cidara Therapeutics, Inc. Antifungal agents
US20180256673A1 (en) * 2015-09-16 2018-09-13 Cidara Therapeutics, Inc. Methods for treating fungal infections
CN106674333B (zh) * 2015-11-06 2020-10-27 博瑞生物医药(苏州)股份有限公司 一种环肽类抗真菌化合物及其制备方法
CN108883152A (zh) * 2016-01-08 2018-11-23 奇达拉治疗公司 防止和治疗肺孢子虫感染的方法
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CA3061164A1 (en) 2017-04-25 2018-11-01 Prothera Biologics, Inc. Methods for quantifying inter-alpha inhibitor proteins
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CN112839951B (zh) * 2018-06-15 2025-12-09 纳普制药集团有限公司 棘白菌素类抗真菌剂的合成
WO2020086931A1 (en) * 2018-10-25 2020-04-30 Cidara Therapeutics, Inc. Polymorph of echinocandin antifungal agent
MX2022006424A (es) 2019-12-06 2022-06-22 Shanghai Senhui Medicine Co Ltd Analogos de equinocandina y metodo de preparacion de los mismos.
TW202313656A (zh) 2021-06-03 2023-04-01 大陸商上海森輝醫藥有限公司 一種阿尼芬淨衍生物的製備方法
CN115850383A (zh) * 2022-12-15 2023-03-28 江苏九阳生物制药有限公司 一种雷扎芬净纯化方法
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

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Also Published As

Publication number Publication date
JP6111447B2 (ja) 2017-04-12
PL2680873T3 (pl) 2018-01-31
US20130244930A1 (en) 2013-09-19
JP6302108B2 (ja) 2018-03-28
SMT201700460T1 (it) 2018-01-11
HRP20171579T8 (hr) 2018-12-14
SI2680873T1 (sl) 2017-12-29
US20170253635A1 (en) 2017-09-07
NO2680873T3 (pt) 2018-01-06
US20150024997A1 (en) 2015-01-22
US20250289852A1 (en) 2025-09-18
JP2017132770A (ja) 2017-08-03
EP2680873B1 (en) 2017-08-09
FR24C1027I2 (fr) 2025-05-23
CN103889221A (zh) 2014-06-25
HUE036778T2 (hu) 2018-07-30
EP2680873A2 (en) 2014-01-08
EP3192803B1 (en) 2020-12-09
ES2645074T8 (es) 2018-09-28
US8722619B2 (en) 2014-05-13
DK2680873T3 (en) 2017-10-30
NL301280I2 (nl) 2024-08-01
US12344680B2 (en) 2025-07-01
CN103889221B (zh) 2016-08-31
JP2014516339A (ja) 2014-07-10
FR24C1027I1 (fr) 2024-08-30
WO2012119065A2 (en) 2012-09-07
HUS2400021I1 (hu) 2024-07-28
CA2865791C (en) 2019-10-08
LT2680873T (lt) 2017-11-27
LTPA2024520I1 (pt) 2024-07-10
JP2016029052A (ja) 2016-03-03
JP5809296B2 (ja) 2015-11-10
CN106279369A (zh) 2017-01-04
US9676821B2 (en) 2017-06-13
FIC20240022I1 (fi) 2024-06-19
RS56426B1 (sr) 2018-01-31
CY2024022I1 (el) 2025-03-28
WO2012119065A3 (en) 2014-03-13
JP2018118977A (ja) 2018-08-02
CA2865791A1 (en) 2012-09-07
US20160075740A1 (en) 2016-03-17
US20220162263A1 (en) 2022-05-26
CY1119709T1 (el) 2018-06-27
CY2024022I2 (el) 2025-03-28
EP3192803A1 (en) 2017-07-19
ES2645074T3 (es) 2017-12-04
CA3053850A1 (en) 2012-09-07
CN106279369B (zh) 2020-02-11
HRP20171579T1 (hr) 2018-02-09
US9217014B2 (en) 2015-12-22
EP2680873A4 (en) 2015-08-26

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