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PT2482841T - A presente invenção refere-se à utilização de lactonas macrocíclicas para o tratamento da demodicose, em particular em cães. - Google Patents

A presente invenção refere-se à utilização de lactonas macrocíclicas para o tratamento da demodicose, em particular em cães.

Info

Publication number
PT2482841T
PT2482841T PT10821393T PT10821393T PT2482841T PT 2482841 T PT2482841 T PT 2482841T PT 10821393 T PT10821393 T PT 10821393T PT 10821393 T PT10821393 T PT 10821393T PT 2482841 T PT2482841 T PT 2482841T
Authority
PT
Portugal
Prior art keywords
compositions
methods
factor viii
coagulation factor
viii function
Prior art date
Application number
PT10821393T
Other languages
English (en)
Inventor
ARRUDA Valder
Camire Rodney
Iacobelli Nicholas
Original Assignee
Childrens Hospital Philadelphia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43826687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2482841(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Childrens Hospital Philadelphia filed Critical Childrens Hospital Philadelphia
Publication of PT2482841T publication Critical patent/PT2482841T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT10821393T 2009-10-02 2010-10-04 A presente invenção refere-se à utilização de lactonas macrocíclicas para o tratamento da demodicose, em particular em cães. PT2482841T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24817909P 2009-10-02 2009-10-02

Publications (1)

Publication Number Publication Date
PT2482841T true PT2482841T (pt) 2019-03-01

Family

ID=43826687

Family Applications (1)

Application Number Title Priority Date Filing Date
PT10821393T PT2482841T (pt) 2009-10-02 2010-10-04 A presente invenção refere-se à utilização de lactonas macrocíclicas para o tratamento da demodicose, em particular em cães.

Country Status (8)

Country Link
US (3) US8816054B2 (pt)
EP (1) EP2482841B2 (pt)
AU (1) AU2010300292B2 (pt)
CA (1) CA2776503C (pt)
DK (1) DK2482841T4 (pt)
ES (1) ES2717902T5 (pt)
PT (1) PT2482841T (pt)
WO (1) WO2011041770A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013086125A2 (en) * 2011-12-08 2013-06-13 Bloodcenter Research Foundation Method of inducing immune tolerance through targetted gene expression
EP3404105A1 (en) 2012-07-06 2018-11-21 Bioverativ Therapeutics Inc. Cell line expressing single chain factor viii polypeptides and uses thereof
CN107427557B (zh) * 2014-08-13 2022-01-04 费城儿童医院 用于包装和表达变体因子viii以治疗血友病的改良表达组件
WO2017123961A1 (en) * 2016-01-14 2017-07-20 The Children's Hospital Of Philadelphia Factor viii variants, nucleic acid sequences, and methods and uses for treatment of hemostasis disorders
US12161696B2 (en) 2016-12-02 2024-12-10 Bioverativ Therapeutics Inc. Methods of treating hemophilic arthropathy using chimeric clotting factors
WO2019067766A1 (en) 2017-09-27 2019-04-04 Sigilon Therapeutics, Inc. METHODS, COMPOSITIONS AND IMPLANTABLE ELEMENTS COMPRISING ACTIVE CELLS
WO2019195056A1 (en) 2018-04-04 2019-10-10 Sigilon Therapeutics, Inc. Methods, compositions, and implantable elements comprising stem cells
UY38160A (es) 2018-04-04 2019-11-29 Sigilon Therapeutics Inc Partículas implantables y métodos relacionados
TW202015723A (zh) 2018-05-18 2020-05-01 美商百歐維拉提夫治療公司 治療a型血友病的方法
UY38389A (es) 2018-09-27 2020-04-30 Sigilon Therapeutics Inc Dispositivos implantables para terapia celular y métodos relacionados
AU2019366942B2 (en) 2018-10-23 2025-10-30 The Children's Hospital Of Philadelphia Compositions and methods for modulating factor VIII function
AU2020221340A1 (en) 2019-02-15 2021-09-16 Bayer Healthcare Llc Gene editing for hemophilia A with improved Factor VIII expression
EP3736286A1 (en) 2019-05-09 2020-11-11 Biotest AG Single chain factor viii molecule
EP4602155A1 (en) 2022-10-11 2025-08-20 Sigilon Therapeutics, Inc. Engineered cells and implantable elements for treatment of disease
CN120659872A (zh) 2022-10-11 2025-09-16 西吉隆医疗股份有限公司 用于治疗疾病的经工程化的细胞和可植入元件

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR910006424B1 (ko) 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
US5451521A (en) 1986-05-29 1995-09-19 Genetics Institute, Inc. Procoagulant proteins
US5422260A (en) 1986-05-29 1995-06-06 Genetics Institute, Inc. -Legal Affairs Human factor VIII:c muteins
WO1988005825A1 (en) 1987-01-30 1988-08-11 Biogen N.V. A method for producing factor viii in high yield
EP0294910B1 (en) 1987-06-12 1996-09-11 Immuno Ag Novel proteins with factor VIII activity, process for their preparation using genetically engineered cells and pharmaceutical compositions containing them
DE3720246A1 (de) 1987-06-19 1988-12-29 Behringwerke Ag Faktor viii:c-aehnliches molekuel mit koagulationsaktivitaet
CA2264431A1 (en) * 1998-03-05 1999-09-05 Queen's University At Kingston Canine factor viii gene, protein and methods of use
BRPI0109494B8 (pt) 2000-03-22 2021-05-25 Octagene Gmbh muteína de fator viii, sequência de dna, vetor, processo para produção da muteína de fator viii, composição farmacêutica e uso da muteína do fator viii
WO2003100053A1 (en) 2002-05-22 2003-12-04 The Children's Hospital Of Philadelphia Compositions and methods for the treatment of hemophilia a
US7041635B2 (en) 2003-01-28 2006-05-09 In2Gen Co., Ltd. Factor VIII polypeptide

Also Published As

Publication number Publication date
AU2010300292B2 (en) 2016-11-10
EP2482841A4 (en) 2013-07-03
CA2776503C (en) 2020-07-28
ES2717902T3 (es) 2019-06-26
US9670267B2 (en) 2017-06-06
WO2011041770A1 (en) 2011-04-07
US20170369554A1 (en) 2017-12-28
EP2482841B2 (en) 2022-09-28
EP2482841A1 (en) 2012-08-08
US10442850B2 (en) 2019-10-15
EP2482841B1 (en) 2018-11-21
US8816054B2 (en) 2014-08-26
US20120308641A1 (en) 2012-12-06
CA2776503A1 (en) 2011-04-07
DK2482841T4 (da) 2022-10-24
DK2482841T3 (en) 2019-03-18
ES2717902T5 (es) 2022-11-29
US20150056271A1 (en) 2015-02-26
AU2010300292A1 (en) 2012-05-03

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