PT2368118E - Biomarcadores para inibidores com atividade anti-angiogénica - Google Patents
Biomarcadores para inibidores com atividade anti-angiogénica Download PDFInfo
- Publication number
- PT2368118E PT2368118E PT97751143T PT09775114T PT2368118E PT 2368118 E PT2368118 E PT 2368118E PT 97751143 T PT97751143 T PT 97751143T PT 09775114 T PT09775114 T PT 09775114T PT 2368118 E PT2368118 E PT 2368118E
- Authority
- PT
- Portugal
- Prior art keywords
- biomarkers
- inhibitors
- angiogenic activity
- angiogenic
- activity
- Prior art date
Links
- 230000001772 anti-angiogenic effect Effects 0.000 title 1
- 239000000090 biomarker Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08022436 | 2008-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2368118E true PT2368118E (pt) | 2014-01-13 |
Family
ID=41666642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97751143T PT2368118E (pt) | 2008-12-23 | 2009-12-14 | Biomarcadores para inibidores com atividade anti-angiogénica |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20120004129A1 (pt) |
| EP (2) | EP2706358A3 (pt) |
| JP (1) | JP5680547B2 (pt) |
| KR (1) | KR101717304B1 (pt) |
| CN (1) | CN102265156B (pt) |
| AU (1) | AU2009331955B2 (pt) |
| CA (1) | CA2747937C (pt) |
| DK (1) | DK2368118T3 (pt) |
| EA (1) | EA020764B1 (pt) |
| ES (1) | ES2440565T3 (pt) |
| MX (1) | MX2011006675A (pt) |
| PL (1) | PL2368118T3 (pt) |
| PT (1) | PT2368118E (pt) |
| WO (1) | WO2010072348A1 (pt) |
| ZA (1) | ZA201105437B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2336185A1 (en) | 2002-03-13 | 2011-06-22 | Biogen Idec Inc. | Anti- alpha v beta 6 antibodies |
| EP2016394A4 (en) | 2006-04-04 | 2013-04-24 | Singulex Inc | METHOD AND COMPOSITIONS FOR HIGHLY SENSITIVE ANALYSIS OF MARKERS AND DETECTION OF MOLECULES |
| US7838250B1 (en) | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| AU2010259022B2 (en) | 2009-06-08 | 2016-05-12 | Singulex, Inc. | Highly sensitive biomarker panels |
| US8759298B2 (en) | 2010-05-03 | 2014-06-24 | Scott & White Healthcare | Protein therapy for corneal inflammation, epithelial wound healing, and photoreceptor degeneration |
| PL2672994T3 (pl) | 2011-02-11 | 2018-11-30 | Merck Patent Gmbh | Przeciwciało przeciwko integrynie alfa-v do leczenia raka prostaty |
| BR112013031019A2 (pt) * | 2011-06-02 | 2017-03-21 | Almac Diagnostics Ltd | teste diagnóstico molecular para câncer |
| EP2831104B1 (en) * | 2012-03-29 | 2021-04-21 | Biogen MA Inc. | Biomarkers for use in integrin therapy applications |
| US11091809B2 (en) | 2012-12-03 | 2021-08-17 | Almac Diagnostic Services Limited | Molecular diagnostic test for cancer |
| CN103083686B (zh) * | 2013-02-18 | 2014-09-10 | 上海交通大学医学院附属仁济医院 | Dkk4基因及其编码蛋白在制备药物中的应用 |
| US10035859B2 (en) | 2013-03-15 | 2018-07-31 | Biogen Ma Inc. | Anti-alpha V beta 6 antibodies and uses thereof |
| WO2014143739A2 (en) | 2013-03-15 | 2014-09-18 | Biogen Idec Ma Inc. | Anti-alpha v beta 6 antibodies and uses thereof |
| GB201409479D0 (en) | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| ES2856348T3 (es) * | 2014-09-17 | 2021-09-27 | Merck Patent Gmbh | Un método para el tratamiento de cánceres sólidos y/o metástasis de los mismos, medicamentos relacionados, y un método para la predicción de la evolución clínica del tratamiento de cánceres sólidos y/o metástasis de los mismos |
| ES2897782T3 (es) * | 2014-09-17 | 2022-03-02 | Merck Patent Gmbh | Método de tratamiento de las enfermedades de la metástasis ósea, medicamentos para el tratamiento y método para predecir el resultado clínico del tratamiento de las enfermedades causadas por metástasis ósea |
| KR101751929B1 (ko) * | 2015-01-05 | 2017-06-28 | 서울대학교 산학협력단 | 신규 간암 환자의 소라페닙 저항성 예측 마커 |
| WO2017042812A2 (en) | 2015-09-10 | 2017-03-16 | Magentiq Eye Ltd. | A system and method for detection of suspicious tissue regions in an endoscopic procedure |
| EP3364190A1 (en) * | 2017-02-20 | 2018-08-22 | Panka Cancer Research AG | Method of detecting cancer or cancer cells |
| WO2019072888A1 (en) * | 2017-10-11 | 2019-04-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | METHODS OF PREDICTING THE THERAPEUTIC RESPONSE IN HEPATOCELLULAR CANCER |
| BR112021001798A2 (pt) * | 2018-07-31 | 2021-04-27 | F. Hoffmann-La Roche Ag | métodos para avaliar a fibrilação atrial, para diagnosticar insuficiência cardíaca, para auxiliar na avaliação da fibrilação atrial, para prever o risco de acidente vascular cerebral e para aprimorar a precisão da previsão, usos e kit |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
| DE69531187T2 (de) | 1994-12-20 | 2004-04-22 | Merck Patent Gmbh | Monoklonaler Antikörper gegen das Alpha-V-Integrin |
| DE19534177A1 (de) | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| US6521593B1 (en) | 1999-02-01 | 2003-02-18 | Childrens Hospital Los Angeles | Methods for inhibiting brain tumor growth |
| DK1381382T3 (da) | 2000-11-01 | 2009-02-02 | Merck Patent Gmbh | Fremgangsmåder og præparater til behandling af öjensygdomme |
| GB0202881D0 (en) * | 2002-02-07 | 2002-03-27 | Univ Cambridge Tech | Improvements relating to diagnostics |
| GB0330002D0 (en) * | 2003-12-24 | 2004-01-28 | Astrazeneca Ab | Quinazoline derivatives |
| CN1977049A (zh) * | 2004-04-26 | 2007-06-06 | 儿童医疗中心有限公司 | 用于检测疾病的血小板生物标志物 |
| KR20070043868A (ko) * | 2004-08-02 | 2007-04-25 | 칠드런'즈 메디컬 센터 코포레이션 | 암에 대한 혈소판 바이오마커 |
| SG158089A1 (en) * | 2004-12-17 | 2010-01-29 | Genentech Inc | Antiangiogenesis therapy of autoimmune disease in patients who have failed prior therapy |
| WO2007022412A2 (en) * | 2005-08-18 | 2007-02-22 | The General Hospital Corporation | Combination therapy for preventing angiogenesis comprising a inhibitor ofhif-1 and a further anti-angiogenic agent |
| US8158107B2 (en) * | 2005-09-30 | 2012-04-17 | National Jewish Health | Genes and proteins associated with angiogenesis and uses thereof |
| KR101559596B1 (ko) | 2007-07-17 | 2015-10-12 | 메르크 파텐트 게엠베하 | 조작 항-알파 ｖ-인테그린 잡종 항체 |
-
2009
- 2009-12-14 US US13/141,616 patent/US20120004129A1/en not_active Abandoned
- 2009-12-14 KR KR1020117017291A patent/KR101717304B1/ko not_active Expired - Fee Related
- 2009-12-14 WO PCT/EP2009/008929 patent/WO2010072348A1/en not_active Ceased
- 2009-12-14 EA EA201100965A patent/EA020764B1/ru not_active IP Right Cessation
- 2009-12-14 AU AU2009331955A patent/AU2009331955B2/en not_active Ceased
- 2009-12-14 CN CN200980152028.4A patent/CN102265156B/zh not_active Expired - Fee Related
- 2009-12-14 EP EP13004904.2A patent/EP2706358A3/en not_active Withdrawn
- 2009-12-14 ES ES09775114.3T patent/ES2440565T3/es active Active
- 2009-12-14 MX MX2011006675A patent/MX2011006675A/es active IP Right Grant
- 2009-12-14 PL PL09775114T patent/PL2368118T3/pl unknown
- 2009-12-14 JP JP2011542699A patent/JP5680547B2/ja not_active Expired - Fee Related
- 2009-12-14 DK DK09775114.3T patent/DK2368118T3/da active
- 2009-12-14 PT PT97751143T patent/PT2368118E/pt unknown
- 2009-12-14 EP EP09775114.3A patent/EP2368118B1/en active Active
- 2009-12-14 CA CA2747937A patent/CA2747937C/en active Active
-
2011
- 2011-07-22 ZA ZA2011/05437A patent/ZA201105437B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL2368118T3 (pl) | 2014-03-31 |
| CN102265156B (zh) | 2014-11-05 |
| JP2012513422A (ja) | 2012-06-14 |
| MX2011006675A (es) | 2011-07-12 |
| US20120004129A1 (en) | 2012-01-05 |
| EP2368118A1 (en) | 2011-09-28 |
| EP2706358A2 (en) | 2014-03-12 |
| CA2747937C (en) | 2019-02-26 |
| EP2368118B1 (en) | 2013-10-16 |
| AU2009331955B2 (en) | 2015-09-24 |
| JP5680547B2 (ja) | 2015-03-04 |
| ES2440565T3 (es) | 2014-01-29 |
| CA2747937A1 (en) | 2010-07-01 |
| EA020764B1 (ru) | 2015-01-30 |
| EA201100965A1 (ru) | 2012-05-30 |
| ZA201105437B (en) | 2012-03-28 |
| KR101717304B1 (ko) | 2017-03-16 |
| CN102265156A (zh) | 2011-11-30 |
| KR20110116021A (ko) | 2011-10-24 |
| AU2009331955A1 (en) | 2011-08-04 |
| DK2368118T3 (da) | 2013-11-25 |
| EP2706358A3 (en) | 2014-05-07 |
| WO2010072348A1 (en) | 2010-07-01 |
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