PT2044020E - Formas cristalinas de 4-[2-(4-metilfenilsulfanil)- fenil] piperidina com inibi??o de reabsor??o combinada de serotonina e norepinefrina para o tratamento da dor neurop?tica - Google Patents
Formas cristalinas de 4-[2-(4-metilfenilsulfanil)- fenil] piperidina com inibi??o de reabsor??o combinada de serotonina e norepinefrina para o tratamento da dor neurop?tica Download PDFInfo
- Publication number
- PT2044020E PT2044020E PT07764496T PT07764496T PT2044020E PT 2044020 E PT2044020 E PT 2044020E PT 07764496 T PT07764496 T PT 07764496T PT 07764496 T PT07764496 T PT 07764496T PT 2044020 E PT2044020 E PT 2044020E
- Authority
- PT
- Portugal
- Prior art keywords
- methylphenylsulfanyl
- piperidine
- phenyl
- treatment
- neuropathic pain
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title 2
- CVASBKDYSQKLSO-UHFFFAOYSA-N Tedatioxetine Chemical compound C1=CC(C)=CC=C1SC1=CC=CC=C1C1CCNCC1 CVASBKDYSQKLSO-UHFFFAOYSA-N 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 208000004296 neuralgia Diseases 0.000 title 1
- 208000021722 neuropathic pain Diseases 0.000 title 1
- 230000000966 norepinephrine reuptake Effects 0.000 title 1
- 229940076279 serotonin Drugs 0.000 title 1
- 230000000697 serotonin reuptake Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/08—Malonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/12—Glutaric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/08—Lactic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80500906P | 2006-06-16 | 2006-06-16 | |
| DKPA200600816 | 2006-06-16 | ||
| DKPA200700423 | 2007-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2044020E true PT2044020E (pt) | 2011-05-12 |
Family
ID=39722478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT07764496T PT2044020E (pt) | 2006-06-16 | 2007-06-15 | Formas cristalinas de 4-[2-(4-metilfenilsulfanil)- fenil] piperidina com inibi??o de reabsor??o combinada de serotonina e norepinefrina para o tratamento da dor neurop?tica |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JP2014098017A (zh) |
| KR (1) | KR101472595B1 (zh) |
| AR (1) | AR061480A1 (zh) |
| AT (1) | ATE508115T1 (zh) |
| BR (1) | BRPI0712758A2 (zh) |
| CA (1) | CA2784304A1 (zh) |
| DE (1) | DE602007014372D1 (zh) |
| DK (1) | DK2044020T3 (zh) |
| MY (1) | MY150698A (zh) |
| NZ (1) | NZ572856A (zh) |
| PT (1) | PT2044020E (zh) |
| RS (1) | RS51687B (zh) |
| SI (1) | SI2044020T1 (zh) |
| TN (1) | TNSN08461A1 (zh) |
| TW (1) | TWI444365B (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101972931B1 (ko) | 2017-10-19 | 2019-04-26 | 재단법인대구경북과학기술원 | 풍선 타입 피질전도 측정장치 및 이의 제조방법 |
| CN116930385B (zh) * | 2023-08-08 | 2024-02-20 | 北京爱思益普生物科技股份有限公司 | 一种高盐浓度制剂中化合物浓度的测定方法 |
| CN117305360B (zh) * | 2023-09-15 | 2024-09-24 | 江南大学 | 一种哺乳动物细胞核转染液及其制备方法和在细胞核内递送的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| AU2007260356B2 (en) * | 2006-06-16 | 2013-01-24 | H. Lundbeck A/S | Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain |
-
2007
- 2007-06-15 CA CA2784304A patent/CA2784304A1/en not_active Abandoned
- 2007-06-15 DE DE602007014372T patent/DE602007014372D1/de active Active
- 2007-06-15 SI SI200730594T patent/SI2044020T1/sl unknown
- 2007-06-15 RS RS20110223A patent/RS51687B/sr unknown
- 2007-06-15 NZ NZ572856A patent/NZ572856A/en not_active IP Right Cessation
- 2007-06-15 AT AT07764496T patent/ATE508115T1/de active
- 2007-06-15 PT PT07764496T patent/PT2044020E/pt unknown
- 2007-06-15 MY MYPI20084894 patent/MY150698A/en unknown
- 2007-06-15 AR ARP070102640A patent/AR061480A1/es unknown
- 2007-06-15 DK DK07764496.1T patent/DK2044020T3/da active
- 2007-06-15 BR BRPI0712758-8A patent/BRPI0712758A2/pt not_active IP Right Cessation
- 2007-06-20 TW TW096121999A patent/TWI444365B/zh not_active IP Right Cessation
-
2008
- 2008-11-17 TN TNP2008000461A patent/TNSN08461A1/en unknown
- 2008-12-11 KR KR1020087030260A patent/KR101472595B1/ko not_active Expired - Fee Related
-
2014
- 2014-02-03 JP JP2014018411A patent/JP2014098017A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| KR20090018630A (ko) | 2009-02-20 |
| DK2044020T3 (da) | 2011-08-15 |
| CA2784304A1 (en) | 2007-12-21 |
| RS51687B (sr) | 2011-10-31 |
| DE602007014372D1 (de) | 2011-06-16 |
| MY150698A (en) | 2014-02-28 |
| KR101472595B1 (ko) | 2014-12-15 |
| SI2044020T1 (sl) | 2011-06-30 |
| TWI444365B (zh) | 2014-07-11 |
| AR061480A1 (es) | 2008-08-27 |
| TW200817329A (en) | 2008-04-16 |
| NZ572856A (en) | 2012-02-24 |
| BRPI0712758A2 (pt) | 2012-09-25 |
| ATE508115T1 (de) | 2011-05-15 |
| JP2014098017A (ja) | 2014-05-29 |
| TNSN08461A1 (en) | 2010-04-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL195310A0 (en) | Crystalline forms of 4-[2-(4-methylphenylsulfanyl)- phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain | |
| IL197420A0 (en) | Polymorphic form of 4-[3-(4-cyclopropanecarbonyl-piperazine-1- | |
| PL2139479T3 (pl) | 4-[2-(4-Metylofenylosulfanylo)fenylo]piperydyna o połączonym hamowaniu wychwytu zwrotnego serotoniny i norepinefryny do leczenia ADHD, melancholii, depresji opornej na leczenie lub pozostałych objawów depresji | |
| IL195273A0 (en) | Pharmaceutical use of substituted piperidine carboxamides | |
| IL192241A (en) | A process for making 4 - (benzimidazolylmethylamino) - benzamides and their salts | |
| EP2358691B8 (en) | Process for the preparation of piperazine compounds and hydrochloride salts thereof | |
| EP1976377A4 (en) | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | |
| EP1983972A4 (en) | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | |
| IL195203A0 (en) | Compounds for the treatment of metabolic disorders | |
| IL192852A0 (en) | Compounds for the treatment of metabolic disorders | |
| NZ592543A (en) | 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds | |
| PT2044020E (pt) | Formas cristalinas de 4-[2-(4-metilfenilsulfanil)- fenil] piperidina com inibi??o de reabsor??o combinada de serotonina e norepinefrina para o tratamento da dor neurop?tica | |
| GB0700830D0 (en) | Crystalline duloxetine hydrochloride | |
| ZA200809917B (en) | Crystalline forms of 4- [2-(4-Methylphenylsulfanyl) - Phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain | |
| IL200959A0 (en) | Liquid formulations of salts of 4-[2-(4-methylphenylfanyl)phenyl]piperidine | |
| IL192851A0 (en) | Compounds for the treatment of metabolic disorders | |
| ZA200801703B (en) | 3-(2-(Dimethylamino)methyl(cyclohex-1-yl))phenol maleate and its crystalline forms | |
| IL198999A0 (en) | Compounds with a combination of cannabinobi-cb1 antagonism and serotonin reuptake inhibition | |
| IL192982A0 (en) | Compounds for the treatment of metabolic disorders | |
| HUP0600946A2 (en) | Process for the preparation of duloxetine and the new intermediates | |
| HK1124587A (zh) | 曲美布汀和n-去甲基曲美布汀的盐 |