PT1819353E - Composi??o para inibi??o de proteassoma - Google Patents
Composi??o para inibi??o de proteassoma Download PDFInfo
- Publication number
- PT1819353E PT1819353E PT05853385T PT05853385T PT1819353E PT 1819353 E PT1819353 E PT 1819353E PT 05853385 T PT05853385 T PT 05853385T PT 05853385 T PT05853385 T PT 05853385T PT 1819353 E PT1819353 E PT 1819353E
- Authority
- PT
- Portugal
- Prior art keywords
- composition
- compositions
- proteasome inhibition
- proteasome inhibitors
- cyclodextrin
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 102000004245 Proteasome Endopeptidase Complex Human genes 0.000 title 1
- 108090000708 Proteasome Endopeptidase Complex Proteins 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 2
- 229940079156 Proteasome inhibitor Drugs 0.000 abstract 2
- 239000003207 proteasome inhibitor Substances 0.000 abstract 2
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 2
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/396—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
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- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
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- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Psychology (AREA)
- Biochemistry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63436604P | 2004-12-07 | 2004-12-07 | |
| US65593005P | 2005-02-23 | 2005-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1819353E true PT1819353E (pt) | 2011-05-12 |
Family
ID=36143200
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT101794220T PT2261236E (pt) | 2004-12-07 | 2005-12-07 | Composição para a inibição de proteassoma |
| PT101789980T PT2260835E (pt) | 2004-12-07 | 2005-12-07 | Composição para inibição do proteassoma |
| PT05853385T PT1819353E (pt) | 2004-12-07 | 2005-12-07 | Composi??o para inibi??o de proteassoma |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT101794220T PT2261236E (pt) | 2004-12-07 | 2005-12-07 | Composição para a inibição de proteassoma |
| PT101789980T PT2260835E (pt) | 2004-12-07 | 2005-12-07 | Composição para inibição do proteassoma |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7737112B2 (pt) |
| EP (3) | EP2261236B1 (pt) |
| JP (1) | JP4990155B2 (pt) |
| KR (1) | KR101299821B1 (pt) |
| CN (2) | CN102847136A (pt) |
| AT (1) | ATE499109T1 (pt) |
| AU (1) | AU2005313975B2 (pt) |
| CA (1) | CA2589921C (pt) |
| CY (1) | CY1111489T1 (pt) |
| DE (1) | DE602005026556D1 (pt) |
| DK (1) | DK1819353T3 (pt) |
| ES (2) | ES2549763T3 (pt) |
| HU (1) | HUE027850T2 (pt) |
| IL (1) | IL183607A (pt) |
| PL (3) | PL2260835T3 (pt) |
| PT (3) | PT2261236E (pt) |
| WO (1) | WO2006063154A1 (pt) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8129346B2 (en) | 2004-04-15 | 2012-03-06 | Onyx Therapeutics, Inc. | Compounds for enzyme inhibition |
| US8198270B2 (en) * | 2004-04-15 | 2012-06-12 | Onyx Therapeutics, Inc. | Compounds for proteasome enzyme inhibition |
| PT2030981E (pt) * | 2004-05-10 | 2014-10-14 | Onyx Therapeutics Inc | Compostos para inibição da enzima proteassoma |
| US9034846B2 (en) * | 2004-10-10 | 2015-05-19 | Universite De Liege | Use of cyclodextrin for treatment and prevention of bronchial inflammatory diseases |
| KR101434522B1 (ko) | 2005-11-09 | 2014-08-26 | 오닉스 세라퓨틱스, 인크. | 효소 저해를 위한 화합물 |
| RU2450016C2 (ru) * | 2006-06-19 | 2012-05-10 | Протеоликс, Инк. | Пептидные эпоксикетоны для ингибирования протеасомы |
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- 2005-12-07 WO PCT/US2005/044451 patent/WO2006063154A1/en not_active Ceased
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- 2005-12-07 HU HUE10179422A patent/HUE027850T2/en unknown
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