PT1753712E - Derivados de amino-propanol - Google Patents
Derivados de amino-propanol Download PDFInfo
- Publication number
- PT1753712E PT1753712E PT05752742T PT05752742T PT1753712E PT 1753712 E PT1753712 E PT 1753712E PT 05752742 T PT05752742 T PT 05752742T PT 05752742 T PT05752742 T PT 05752742T PT 1753712 E PT1753712 E PT 1753712E
- Authority
- PT
- Portugal
- Prior art keywords
- amino
- propanol derivatives
- propanol
- derivatives
- transplantation
- Prior art date
Links
- MXZROAOUCUVNHX-UHFFFAOYSA-N 2-Aminopropanol Chemical class CCC(N)O MXZROAOUCUVNHX-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/094—Esters of phosphoric acids with arylalkanols
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0411929.3A GB0411929D0 (en) | 2004-05-27 | 2004-05-27 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1753712E true PT1753712E (pt) | 2009-08-06 |
Family
ID=32671206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05752742T PT1753712E (pt) | 2004-05-27 | 2005-05-25 | Derivados de amino-propanol |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7928093B2 (pt) |
| EP (1) | EP1753712B1 (pt) |
| JP (1) | JP4490482B2 (pt) |
| KR (1) | KR100837897B1 (pt) |
| CN (1) | CN100575335C (pt) |
| AT (1) | ATE431333T1 (pt) |
| AU (1) | AU2005250112B2 (pt) |
| BR (1) | BRPI0511610A (pt) |
| CA (1) | CA2562332A1 (pt) |
| DE (1) | DE602005014473D1 (pt) |
| ES (1) | ES2327250T3 (pt) |
| GB (1) | GB0411929D0 (pt) |
| MX (1) | MXPA06013624A (pt) |
| PL (1) | PL1753712T3 (pt) |
| PT (1) | PT1753712E (pt) |
| RU (1) | RU2006146215A (pt) |
| WO (1) | WO2005118523A1 (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05011597A (es) * | 2003-04-30 | 2005-12-15 | Novartis Ag | Derivados de aminopropanol como moduladores del receptor 1-fosfato de esfingosina. |
| WO2005041899A2 (en) | 2003-11-03 | 2005-05-12 | University Of Virginia Patent Foundation | Orally available sphingosine 1-phosphate receptor agonists and antagonists |
| PT1772145E (pt) | 2004-07-16 | 2011-05-27 | Kyorin Seiyaku Kk | Processo de utiliza??o eficaz de um medicamento e processo respeitante ? preven??o de efeitos secund?rios |
| EP1781595A1 (en) | 2004-08-13 | 2007-05-09 | Praecis Pharmaceuticals Inc. | Methods and compositions for modulating sphingosine-1-phosphate (s1p) receptor activity |
| BRPI0516337A (pt) * | 2004-10-12 | 2008-04-29 | Kyorin Seiyaku Kk | processo para a produção de 2- amino-2-[4-(3-benziloxifeniltio) -2- (clorofenil} etil] - 1,3 - hidrocloreto de propanediol e hidratos dos mesmos e produtos intermerdiários para a produção dos mesmos |
| MX2007006706A (es) | 2004-12-06 | 2007-10-18 | Univ Virginia | Analogos de esfingosina 1-fosfato amida de arilo. |
| PL1932522T3 (pl) * | 2005-10-07 | 2012-09-28 | Kyorin Seiyaku Kk | Środek terapeutyczny do leczenia choroby wątroby zawierający jako składnik czynny pochodną 2-amino-1,3-propanodiolu |
| JP2009528274A (ja) | 2006-01-27 | 2009-08-06 | ユニバーシティ オブ バージニア パテント ファンデーション | 神経因性疼痛の治療法 |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| EP1987013A1 (en) * | 2006-02-09 | 2008-11-05 | University Of Virginia Patent Foundation | Bicyclic sphingosine 1-phosphate analogs |
| EP2053038B1 (en) * | 2006-08-08 | 2016-10-05 | Kyorin Pharmaceutical Co., Ltd. | Amino alcohol derivative and immunosuppressive agent having same as an active ingredient |
| EP2058317B1 (en) | 2006-08-08 | 2013-10-16 | Kyorin Pharmaceutical Co., Ltd. | Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient |
| CA2669102A1 (en) | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Tetralin analogs having sphingosine 1-phosphate agonist activity |
| JP2010510250A (ja) | 2006-11-21 | 2010-04-02 | ユニバーシティ オブ バージニア パテント ファンデーション | スフィンゴシン=1−燐酸受容体アゴニスト活性を有するヒドリンダンアナログ |
| AU2007323557A1 (en) * | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Benzocycloheptyl analogs having sphingosine 1-phosphate receptor activity |
| WO2008124210A1 (en) * | 2007-02-14 | 2008-10-16 | Emory University | Methods and compositions for treating or preventing infection using leukocyte sequestration agents |
| WO2009099174A1 (ja) | 2008-02-07 | 2009-08-13 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤 |
| PE20100371A1 (es) * | 2008-10-31 | 2010-06-01 | Lexicon Pharmaceuticals Inc | Agonistas del receptor s1p para el tratamiento de malaria cerebral |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0778263B1 (en) | 1994-08-22 | 2002-01-09 | Welfide Corporation | Benzene compound and medicinal use thereof |
| US5948820A (en) * | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
| SI1319651T1 (en) * | 1997-04-04 | 2005-10-31 | Mitsubishi Pharma Corporation | 2-Aminopropane-1,3-diol compound, pharmaceutical use thereof and synthetic intermediates therefor |
| IL157773A0 (en) | 2001-03-26 | 2004-03-28 | Novartis Ag | 2-amino-propanol derivatives |
| BR0314113A (pt) * | 2002-09-13 | 2005-07-12 | Novartis Ag | Derivados de amino propanol |
| MXPA05011597A (es) * | 2003-04-30 | 2005-12-15 | Novartis Ag | Derivados de aminopropanol como moduladores del receptor 1-fosfato de esfingosina. |
-
2004
- 2004-05-27 GB GBGB0411929.3A patent/GB0411929D0/en not_active Ceased
-
2005
- 2005-05-25 DE DE602005014473T patent/DE602005014473D1/de not_active Expired - Lifetime
- 2005-05-25 CA CA002562332A patent/CA2562332A1/en not_active Abandoned
- 2005-05-25 ES ES05752742T patent/ES2327250T3/es not_active Expired - Lifetime
- 2005-05-25 KR KR1020067024709A patent/KR100837897B1/ko not_active Expired - Fee Related
- 2005-05-25 JP JP2007513805A patent/JP4490482B2/ja not_active Expired - Fee Related
- 2005-05-25 US US11/568,645 patent/US7928093B2/en not_active Expired - Fee Related
- 2005-05-25 RU RU2006146215/04A patent/RU2006146215A/ru not_active Application Discontinuation
- 2005-05-25 CN CN200580012823A patent/CN100575335C/zh not_active Expired - Fee Related
- 2005-05-25 AT AT05752742T patent/ATE431333T1/de active
- 2005-05-25 AU AU2005250112A patent/AU2005250112B2/en not_active Ceased
- 2005-05-25 PT PT05752742T patent/PT1753712E/pt unknown
- 2005-05-25 PL PL05752742T patent/PL1753712T3/pl unknown
- 2005-05-25 EP EP05752742A patent/EP1753712B1/en not_active Expired - Lifetime
- 2005-05-25 WO PCT/EP2005/005685 patent/WO2005118523A1/en not_active Ceased
- 2005-05-25 MX MXPA06013624A patent/MXPA06013624A/es active IP Right Grant
- 2005-05-25 BR BRPI0511610-4A patent/BRPI0511610A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20070225260A1 (en) | 2007-09-27 |
| CN100575335C (zh) | 2009-12-30 |
| ES2327250T3 (es) | 2009-10-27 |
| MXPA06013624A (es) | 2007-02-28 |
| EP1753712A1 (en) | 2007-02-21 |
| WO2005118523A1 (en) | 2005-12-15 |
| EP1753712B1 (en) | 2009-05-13 |
| GB0411929D0 (en) | 2004-06-30 |
| CA2562332A1 (en) | 2005-12-15 |
| ATE431333T1 (de) | 2009-05-15 |
| RU2006146215A (ru) | 2008-07-10 |
| JP2008500302A (ja) | 2008-01-10 |
| JP4490482B2 (ja) | 2010-06-23 |
| PL1753712T3 (pl) | 2009-10-30 |
| AU2005250112B2 (en) | 2009-01-08 |
| CN1946679A (zh) | 2007-04-11 |
| DE602005014473D1 (en) | 2009-06-25 |
| BRPI0511610A (pt) | 2008-01-02 |
| KR20070015439A (ko) | 2007-02-02 |
| AU2005250112A1 (en) | 2005-12-15 |
| KR100837897B1 (ko) | 2008-06-13 |
| US7928093B2 (en) | 2011-04-19 |
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