[go: up one dir, main page]

PT1649051E - Determinação da sequência de um polinucleótido - Google Patents

Determinação da sequência de um polinucleótido Download PDF

Info

Publication number
PT1649051E
PT1649051E PT04743561T PT04743561T PT1649051E PT 1649051 E PT1649051 E PT 1649051E PT 04743561 T PT04743561 T PT 04743561T PT 04743561 T PT04743561 T PT 04743561T PT 1649051 E PT1649051 E PT 1649051E
Authority
PT
Portugal
Prior art keywords
target polynucleotide
sequence
polymerase
polynucleotide
determining
Prior art date
Application number
PT04743561T
Other languages
English (en)
Inventor
Daniel Henry Densham
Original Assignee
Medical Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Biosystems Ltd filed Critical Medical Biosystems Ltd
Publication of PT1649051E publication Critical patent/PT1649051E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/10Nucleotidyl transfering
    • C12Q2521/101DNA polymerase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00Reactions demanding special reaction conditions
    • C12Q2527/113Time
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50Detection characterised by immobilisation to a surface
    • C12Q2565/501Detection characterised by immobilisation to a surface being an array of oligonucleotides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
PT04743561T 2003-07-24 2004-07-26 Determinação da sequência de um polinucleótido PT1649051E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0317343.2A GB0317343D0 (en) 2003-07-24 2003-07-24 Polynucleotide sequencing

Publications (1)

Publication Number Publication Date
PT1649051E true PT1649051E (pt) 2008-05-26

Family

ID=27772590

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04743561T PT1649051E (pt) 2003-07-24 2004-07-26 Determinação da sequência de um polinucleótido

Country Status (21)

Country Link
US (3) US7604963B2 (pt)
EP (1) EP1649051B1 (pt)
JP (1) JP4394684B2 (pt)
KR (1) KR20060052863A (pt)
CN (1) CN1852991A (pt)
AT (1) ATE388243T1 (pt)
AU (1) AU2004259893A1 (pt)
BR (1) BRPI0412813A (pt)
CA (2) CA2780958C (pt)
DE (1) DE602004012273T2 (pt)
DK (1) DK1649051T3 (pt)
ES (1) ES2303083T3 (pt)
GB (1) GB0317343D0 (pt)
IL (1) IL173314A0 (pt)
IS (1) IS8314A (pt)
MX (1) MXPA06000962A (pt)
PL (1) PL1649051T3 (pt)
PT (1) PT1649051E (pt)
RU (1) RU2006105626A (pt)
SI (1) SI1649051T1 (pt)
WO (1) WO2005010210A2 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2267165B1 (en) * 1997-07-28 2016-11-30 Gen-Probe Incorporated Nucleic acid sequence analysis
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
JP2004347621A (ja) * 2003-04-24 2004-12-09 Dainippon Printing Co Ltd 透過型スクリーン
JP4431549B2 (ja) * 2006-05-31 2010-03-17 株式会社日立ハイテクノロジーズ 蛍光分析装置
GB0721340D0 (en) * 2007-10-30 2007-12-12 Isis Innovation Polymerase-based single-molecule DNA sequencing
JP4982523B2 (ja) * 2009-05-11 2012-07-25 株式会社日立ハイテクノロジーズ 蛍光分析方法,蛍光分析装置及び画像検出方法
US9353412B2 (en) 2010-06-18 2016-05-31 Illumina, Inc. Conformational probes and methods for sequencing nucleic acids
US9279154B2 (en) * 2011-12-21 2016-03-08 Illumina, Inc. Apparatus and methods for kinetic analysis and determination of nucleic acid sequences
US9593371B2 (en) * 2013-12-27 2017-03-14 Intel Corporation Integrated photonic electronic sensor arrays for nucleic acid sequencing
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
US10077470B2 (en) 2015-07-21 2018-09-18 Omniome, Inc. Nucleic acid sequencing methods and systems
WO2017176679A1 (en) * 2016-04-04 2017-10-12 The Trustees Of Columbia University In The City Of New York Dna sequencing by synthesis with nucleotide analogues and raman detection
AU2017258619B2 (en) 2016-04-29 2020-05-14 Pacific Biosciences Of California, Inc. Sequencing method employing ternary complex destabilization to identify cognate nucleotides
JP6828140B2 (ja) 2016-08-15 2021-02-10 オムニオム インコーポレイテッドOmniome, Inc. 核酸をシーケンシングするための方法及びシステム
US10428378B2 (en) 2016-08-15 2019-10-01 Omniome, Inc. Sequencing method for rapid identification and processing of cognate nucleotide pairs
US11248254B2 (en) 2016-12-30 2022-02-15 Omniome, Inc. Method and system employing distinguishable polymerases for detecting ternary complexes and identifying cognate nucleotides
US10415029B2 (en) 2017-01-20 2019-09-17 Omniome, Inc. Allele-specific capture of nucleic acids
CA3050695C (en) 2017-01-20 2024-02-20 Omniome, Inc. Process for cognate nucleotide detection in a nucleic acid sequencing workflow
US9932631B1 (en) 2017-09-11 2018-04-03 Omniome, Inc. Genotyping by polymerase binding
US9951385B1 (en) 2017-04-25 2018-04-24 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
US10161003B2 (en) 2017-04-25 2018-12-25 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
AU2018353136B2 (en) 2017-10-19 2022-05-19 Pacific Biosciences Of California, Inc. Simultaneous background reduction and complex stabilization in binding assay workflows
EA202092684A1 (ru) 2018-08-27 2021-03-11 Ридженерон Фармасьютикалз, Инк. Применение рамановской спектроскопии для последующей очистки

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416952B1 (en) * 1989-06-07 2002-07-09 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
PT912766E (pt) * 1996-06-04 2009-07-16 Univ Utah Res Found Monitorização da hibridização durante a pcr
EP2267165B1 (en) 1997-07-28 2016-11-30 Gen-Probe Incorporated Nucleic acid sequence analysis
CN1245218A (zh) 1998-08-19 2000-02-23 中国人民解放军军事医学科学院放射医学研究所 一种固相逐个碱基核酸分析方法和仪器
EP1961826A3 (en) 1999-03-10 2008-09-17 ASM Scientific, Inc. A method for direct nucleic acid sequencing
US7056661B2 (en) * 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
WO2001016375A2 (en) 1999-08-30 2001-03-08 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
US6908736B1 (en) * 1999-10-06 2005-06-21 Medical Biosystems, Ltd. DNA sequencing method
GB9923644D0 (en) 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
GB0112238D0 (en) 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
US6982165B2 (en) * 2001-09-24 2006-01-03 Intel Corporation Nucleic acid sequencing by raman monitoring of molecular deconstruction
GB0413082D0 (en) * 2004-06-11 2004-07-14 Medical Biosystems Ltd Method

Also Published As

Publication number Publication date
ES2303083T3 (es) 2008-08-01
US7604963B2 (en) 2009-10-20
CN1852991A (zh) 2006-10-25
JP4394684B2 (ja) 2010-01-06
WO2005010210A3 (en) 2005-03-24
KR20060052863A (ko) 2006-05-19
DE602004012273D1 (de) 2008-04-17
US8592183B2 (en) 2013-11-26
CA2533579A1 (en) 2005-02-03
WO2005010210A2 (en) 2005-02-03
DE602004012273T2 (de) 2009-04-30
EP1649051A2 (en) 2006-04-26
US20100279288A1 (en) 2010-11-04
CA2780958C (en) 2016-10-25
CA2780958A1 (en) 2005-02-03
MXPA06000962A (es) 2006-03-30
RU2006105626A (ru) 2006-08-10
US20080070236A1 (en) 2008-03-20
CA2533579C (en) 2012-09-11
US7888073B2 (en) 2011-02-15
BRPI0412813A (pt) 2006-09-26
PL1649051T3 (pl) 2008-12-31
ATE388243T1 (de) 2008-03-15
EP1649051B1 (en) 2008-03-05
DK1649051T3 (da) 2008-07-07
US20110097729A1 (en) 2011-04-28
AU2004259893A1 (en) 2005-02-03
IL173314A0 (en) 2006-06-11
IS8314A (is) 2006-02-20
SI1649051T1 (sl) 2008-10-31
JP2006528485A (ja) 2006-12-21
GB0317343D0 (en) 2003-08-27

Similar Documents

Publication Publication Date Title
IL173314A0 (en) Determining the sequence of a polynucleotide
WO2009102878A3 (en) Method for archiving and clonal expansion
DK1778867T3 (da) Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve
WO2004072238A3 (en) Terminal-phosphate-labeled nucleotides with new linkers
WO2009097368A3 (en) Methods and compositions for efficient base calling in sequencing reactions
WO2008014485A3 (en) Multiplex q-pcr arrays
PL1633888T3 (pl) Środki i sposoby detekcji docelowych sekwencji nukleotydowych z użyciem oznaczeń ligacji i par ulepszonych sond oligonukleotydowych
SE0301951D0 (sv) New method
MX2007009809A (es) Amplificacion de sonda por seleccion.
WO2005054270A3 (en) Identification and design of sirna molecules
CN103740824B (zh) 一种两核苷酸实时合成测序图谱鉴定微生物种群的方法
WO2004048397A3 (en) Detectable labeled nucleoside analogs and methods of use thereof
WO2009000764A3 (de) Verfahren und schnelltest zum nachweis spezifischer nukleinsäuresequenzen
TW200506067A (en) Method of detecting target nucleotide sequence, detection target structure to be used in embodying the method, process for producing the same and assay kit for detecting target nucleotide sequence
EP2383349A3 (en) Primer and probe for detection of mycobacterium avium and method for detection of mycobacterium avium using the same
MY149655A (en) Detection and enumeration of microorganisms
WO2004046344A3 (en) Polynucleotide sequence detection assays
WO2005045059A3 (en) Allele assignment and probe selection in multiplexed assays of polymorphic targets
DE602004030036D1 (de) Multiplexanalyse von Nukleinsäuren zur Bestimmung von Genotypen des humanen Papillomavirus
WO2006005081A3 (en) Compositions and methods for identifying nucleotides in polynucleotide sequences
WO2008093336A3 (en) Genome determination assay
GB2444101A (en) Methods and compositions for detecting polynucleotides
WO2007056332A3 (en) Molecular diagnosis of autoimmune diseases
WO2008102606A1 (ja) ゲノムdna断片の増幅または欠失の検出方法
WO2005043114A3 (en) Oligonucleotide probe sets and uses thereof