PT1339399E - Combinacoes de drogas (e.g., clorpromazina e pentamidina) para o tratamento de desordens neoplasicas - Google Patents
Combinacoes de drogas (e.g., clorpromazina e pentamidina) para o tratamento de desordens neoplasicasInfo
- Publication number
- PT1339399E PT1339399E PT01994213T PT01994213T PT1339399E PT 1339399 E PT1339399 E PT 1339399E PT 01994213 T PT01994213 T PT 01994213T PT 01994213 T PT01994213 T PT 01994213T PT 1339399 E PT1339399 E PT 1339399E
- Authority
- PT
- Portugal
- Prior art keywords
- clorpromazine
- pentamidine
- drugs
- combinations
- treatment
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 230000001613 neoplastic effect Effects 0.000 title 1
- XDRYMKDFEDOLFX-UHFFFAOYSA-N pentamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCOC1=CC=C(C(N)=N)C=C1 XDRYMKDFEDOLFX-UHFFFAOYSA-N 0.000 title 1
- 229960004448 pentamidine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/706,929 US6569853B1 (en) | 2000-11-06 | 2000-11-06 | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1339399E true PT1339399E (pt) | 2006-07-31 |
Family
ID=24839666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01994213T PT1339399E (pt) | 2000-11-06 | 2001-10-30 | Combinacoes de drogas (e.g., clorpromazina e pentamidina) para o tratamento de desordens neoplasicas |
Country Status (29)
| Country | Link |
|---|---|
| US (4) | US6569853B1 (pt) |
| EP (1) | EP1339399B1 (pt) |
| JP (1) | JP2004517915A (pt) |
| KR (1) | KR100720205B1 (pt) |
| CN (1) | CN1484525A (pt) |
| AR (1) | AR035500A1 (pt) |
| AT (1) | ATE318590T1 (pt) |
| AU (1) | AU2002246636B8 (pt) |
| BG (1) | BG107831A (pt) |
| BR (1) | BR0115166A (pt) |
| CA (1) | CA2436799C (pt) |
| CY (1) | CY1105501T1 (pt) |
| DE (1) | DE60117615T2 (pt) |
| DK (1) | DK1339399T3 (pt) |
| EE (1) | EE200300212A (pt) |
| ES (1) | ES2258566T3 (pt) |
| HR (1) | HRP20030460A2 (pt) |
| HU (1) | HUP0400529A3 (pt) |
| IL (1) | IL155795A0 (pt) |
| IS (1) | IS2457B (pt) |
| MX (1) | MXPA03003960A (pt) |
| NO (1) | NO20032036L (pt) |
| NZ (1) | NZ525773A (pt) |
| PL (1) | PL362690A1 (pt) |
| PT (1) | PT1339399E (pt) |
| RU (1) | RU2286769C2 (pt) |
| SK (1) | SK5452003A3 (pt) |
| TW (1) | TWI259077B (pt) |
| WO (1) | WO2002058684A2 (pt) |
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| WO2002069949A2 (en) * | 2001-03-06 | 2002-09-12 | Prendergast Patrick T | Combination therapy for reduction of toxycity of chemotherapeutic agents |
| CA2451845A1 (en) * | 2001-05-31 | 2002-12-05 | The Cleveland Clinic Foundation | Ptpase inhibitors and method of using same |
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| AU2004201240B2 (en) * | 2001-09-27 | 2008-08-07 | Bar Ilan University | Conjugated Psychotropic Drugs and Uses Thereof |
| US8053477B2 (en) * | 2002-03-29 | 2011-11-08 | University Of Maryland, Baltimore | Inhibitors of the S100-p53 protein-protein interaction and method of inhibiting cancer employing the same |
| AU2003241346A1 (en) * | 2002-05-01 | 2003-11-17 | The Cleveland Clinic Foundation | Therapeutic compositions comprised of pentamidine and methods of using same to treat cancer |
| EP1545544A2 (en) * | 2002-07-11 | 2005-06-29 | Combinatorx, Incorporated | Combinations of drugs for the treatment of neoplasms |
| EP1606759B1 (en) * | 2003-03-26 | 2010-05-05 | Synergy Biosystems Ltd. | Methods to identify biologically active agents and synergistic combinations |
| EP1651207A4 (en) * | 2003-06-12 | 2008-10-01 | Univ Colorado | SYSTEMS AND METHODS FOR THE TREATMENT OF HUMAN INFLAMMATORY AND PROLIFERATIVE DISEASES AND INJURIES USING INHIBITORS OF FATTY ACID METABOLISM AND / OR GLYCOLYTIC INHIBITORS |
| US20050054708A1 (en) * | 2003-07-28 | 2005-03-10 | Nichols Matthew James | Combinations of drugs for the treatment of neoplasms |
| WO2005020913A2 (en) * | 2003-08-25 | 2005-03-10 | Combinatorx, Incorporated | Formulations, conjugates, and combinations of drugs for the treatment of neoplasms |
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| US20050158320A1 (en) * | 2003-11-12 | 2005-07-21 | Nichols M. J. | Combinations for the treatment of proliferative diseases |
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| JP3679943B2 (ja) * | 1999-03-02 | 2005-08-03 | 大日本印刷株式会社 | パターン形成体の製造方法 |
| DK1231910T3 (da) | 1999-11-16 | 2009-08-31 | Oncozyme Pharma Inc | Pentamidin til behandling af cancer |
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| US6911468B2 (en) * | 2000-05-22 | 2005-06-28 | Takeda Chemical Industries, Ltd. | Tyrosine phosphatase inhibitors |
| US6569853B1 (en) * | 2000-11-06 | 2003-05-27 | Combinatorx, Incorporated | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
| US6642221B1 (en) * | 2000-11-15 | 2003-11-04 | Parker Hughes Institute | Vanadium compounds as anti-proliferative agents |
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| US20030161893A1 (en) * | 2001-09-07 | 2003-08-28 | Taolin Yi | PTPase inhibitors and methods of using the same |
| EP1545544A2 (en) * | 2002-07-11 | 2005-06-29 | Combinatorx, Incorporated | Combinations of drugs for the treatment of neoplasms |
| US20050054708A1 (en) * | 2003-07-28 | 2005-03-10 | Nichols Matthew James | Combinations of drugs for the treatment of neoplasms |
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| US20050100508A1 (en) * | 2003-11-12 | 2005-05-12 | Nichols M. J. | Methods for identifying drug combinations for the treatment of proliferative diseases |
| US20050158320A1 (en) * | 2003-11-12 | 2005-07-21 | Nichols M. J. | Combinations for the treatment of proliferative diseases |
-
2000
- 2000-11-06 US US09/706,929 patent/US6569853B1/en not_active Expired - Fee Related
-
2001
- 2001-10-30 KR KR1020037006212A patent/KR100720205B1/ko not_active Expired - Fee Related
- 2001-10-30 DK DK01994213T patent/DK1339399T3/da active
- 2001-10-30 ES ES01994213T patent/ES2258566T3/es not_active Expired - Lifetime
- 2001-10-30 JP JP2002559018A patent/JP2004517915A/ja active Pending
- 2001-10-30 BR BR0115166-5A patent/BR0115166A/pt not_active Application Discontinuation
- 2001-10-30 CN CNA018217230A patent/CN1484525A/zh active Pending
- 2001-10-30 WO PCT/US2001/047959 patent/WO2002058684A2/en not_active Ceased
- 2001-10-30 AU AU2002246636A patent/AU2002246636B8/en not_active Ceased
- 2001-10-30 CA CA002436799A patent/CA2436799C/en not_active Expired - Fee Related
- 2001-10-30 PT PT01994213T patent/PT1339399E/pt unknown
- 2001-10-30 RU RU2003116898/14A patent/RU2286769C2/ru not_active IP Right Cessation
- 2001-10-30 PL PL01362690A patent/PL362690A1/xx not_active Application Discontinuation
- 2001-10-30 IL IL15579501A patent/IL155795A0/xx unknown
- 2001-10-30 SK SK545-2003A patent/SK5452003A3/sk not_active Application Discontinuation
- 2001-10-30 DE DE60117615T patent/DE60117615T2/de not_active Expired - Fee Related
- 2001-10-30 AT AT01994213T patent/ATE318590T1/de not_active IP Right Cessation
- 2001-10-30 HU HU0400529A patent/HUP0400529A3/hu unknown
- 2001-10-30 EP EP01994213A patent/EP1339399B1/en not_active Expired - Lifetime
- 2001-10-30 MX MXPA03003960A patent/MXPA03003960A/es active IP Right Grant
- 2001-10-30 HR HR20030460A patent/HRP20030460A2/hr not_active Application Discontinuation
- 2001-10-30 EE EEP200300212A patent/EE200300212A/xx unknown
- 2001-10-30 NZ NZ525773A patent/NZ525773A/en unknown
- 2001-11-06 AR ARP010105193A patent/AR035500A1/es not_active Application Discontinuation
- 2001-11-06 TW TW090127505A patent/TWI259077B/zh not_active IP Right Cessation
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2003
- 2003-01-21 US US10/347,714 patent/US6846816B2/en not_active Expired - Fee Related
- 2003-05-05 IS IS6806A patent/IS2457B/is unknown
- 2003-05-06 NO NO20032036A patent/NO20032036L/no not_active Application Discontinuation
- 2003-05-20 BG BG107831A patent/BG107831A/bg unknown
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2004
- 2004-12-28 US US11/024,303 patent/US7148216B2/en not_active Expired - Fee Related
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2006
- 2006-05-19 CY CY20061100653T patent/CY1105501T1/el unknown
- 2006-12-07 US US11/635,704 patent/US20070099906A1/en not_active Abandoned
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