PT1365762E - Processo para aumentar os níveis de leptina utilizando compostos do ácido nicotínico - Google Patents
Processo para aumentar os níveis de leptina utilizando compostos do ácido nicotínico Download PDFInfo
- Publication number
- PT1365762E PT1365762E PT02721337T PT02721337T PT1365762E PT 1365762 E PT1365762 E PT 1365762E PT 02721337 T PT02721337 T PT 02721337T PT 02721337 T PT02721337 T PT 02721337T PT 1365762 E PT1365762 E PT 1365762E
- Authority
- PT
- Portugal
- Prior art keywords
- nicotinic acid
- leptin levels
- acid compounds
- increasing leptin
- increase
- Prior art date
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical class OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 8
- 102000016267 Leptin Human genes 0.000 title abstract 3
- 108010092277 Leptin Proteins 0.000 title abstract 3
- NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 title abstract 3
- 229940039781 leptin Drugs 0.000 title abstract 3
- 229960003512 nicotinic acid Drugs 0.000 abstract 4
- 235000001968 nicotinic acid Nutrition 0.000 abstract 4
- 239000011664 nicotinic acid Substances 0.000 abstract 4
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- -1 nicotinic acid ester Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27434901P | 2001-03-08 | 2001-03-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1365762E true PT1365762E (pt) | 2008-11-27 |
Family
ID=23047813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT02721337T PT1365762E (pt) | 2001-03-08 | 2002-03-08 | Processo para aumentar os níveis de leptina utilizando compostos do ácido nicotínico |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6750234B2 (pt) |
| EP (1) | EP1365762B1 (pt) |
| JP (1) | JP5057353B2 (pt) |
| CN (1) | CN1265792C (pt) |
| AT (1) | ATE409037T1 (pt) |
| CA (1) | CA2437844C (pt) |
| DE (1) | DE60229041D1 (pt) |
| DK (1) | DK1365762T3 (pt) |
| ES (1) | ES2315358T3 (pt) |
| MX (1) | MXPA03008096A (pt) |
| PT (1) | PT1365762E (pt) |
| WO (1) | WO2002072092A1 (pt) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040037828A1 (en) | 2002-07-09 | 2004-02-26 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| AU8436401A (en) | 2000-07-31 | 2002-02-13 | Univ Bar Ilan | Methods and pharmaceutical compositions for healing wounds |
| WO2002072092A1 (en) * | 2001-03-08 | 2002-09-19 | University Of Kentucky | Method for increasing leptin levels using nicotinic acid compounds |
| BR0315942A (pt) | 2002-11-27 | 2005-10-04 | Dmi Biosciences Inc | Tratamento de doenças e condições mediadas pelo aumento de fosforilação |
| US7736636B2 (en) * | 2003-02-12 | 2010-06-15 | Shaker Mousa | Method for treating occlusive vascular diseases & wound healing |
| US7218948B2 (en) | 2003-02-24 | 2007-05-15 | Qualcomm Incorporated | Method of transmitting pilot tones in a multi-sector cell, including null pilot tones, for generating channel quality indicators |
| US9544860B2 (en) | 2003-02-24 | 2017-01-10 | Qualcomm Incorporated | Pilot signals for use in multi-sector cells |
| US8811348B2 (en) | 2003-02-24 | 2014-08-19 | Qualcomm Incorporated | Methods and apparatus for generating, communicating, and/or using information relating to self-noise |
| ATE529125T1 (de) | 2003-08-07 | 2011-11-15 | Healor Ltd | Pharmazeutische zusammensetzungen und verfahren zur beschleunigung der wundheilung |
| US8969291B2 (en) | 2004-10-08 | 2015-03-03 | Enzo Therapeutics, Inc. | Methods for decreasing leptin levels or activity for treating inflammation |
| US8503938B2 (en) | 2004-10-14 | 2013-08-06 | Qualcomm Incorporated | Methods and apparatus for determining, communicating and using information including loading factors which can be used for interference control purposes |
| BRPI0516493A (pt) | 2004-10-14 | 2008-09-09 | Qualcomm Flarion Tech | métodos e aparelho para determinar, comunicar e utilizar informações que podem ser usadas para fins de controle de interferência |
| JP2006253769A (ja) * | 2005-03-08 | 2006-09-21 | National Institute Of Advanced Industrial & Technology | 情報処理システムおよび方法 |
| HUE034582T2 (en) * | 2005-06-24 | 2018-02-28 | Arizona Board Of Regents Acting On Behalf Of The Univ Of Arizona | A method of treating hair growth disorders, such as female alopecia, and compositions for use therein |
| EP2452691A3 (en) | 2005-08-29 | 2012-09-05 | HealOr Ltd. | Methods and compositions for prevention of diabetic and aged skin |
| US20070066512A1 (en) * | 2005-09-12 | 2007-03-22 | Dominique Verhelle | Methods and compositions using immunomodulatory compounds for the treatment of disorders associated with low plasma leptin levels |
| US8989084B2 (en) | 2005-10-14 | 2015-03-24 | Qualcomm Incorporated | Methods and apparatus for broadcasting loading information corresponding to neighboring base stations |
| US9191840B2 (en) | 2005-10-14 | 2015-11-17 | Qualcomm Incorporated | Methods and apparatus for determining, communicating and using information which can be used for interference control |
| US9119220B2 (en) | 2005-12-22 | 2015-08-25 | Qualcomm Incorporated | Methods and apparatus for communicating backlog related information |
| US9148795B2 (en) | 2005-12-22 | 2015-09-29 | Qualcomm Incorporated | Methods and apparatus for flexible reporting of control information |
| US7801589B2 (en) | 2005-12-22 | 2010-09-21 | Olympus Corporation | In-vivo examination method and in-vivo examination apparatus |
| US9473265B2 (en) | 2005-12-22 | 2016-10-18 | Qualcomm Incorporated | Methods and apparatus for communicating information utilizing a plurality of dictionaries |
| US9451491B2 (en) | 2005-12-22 | 2016-09-20 | Qualcomm Incorporated | Methods and apparatus relating to generating and transmitting initial and additional control information report sets in a wireless system |
| US9338767B2 (en) | 2005-12-22 | 2016-05-10 | Qualcomm Incorporated | Methods and apparatus of implementing and/or using a dedicated control channel |
| US9137072B2 (en) | 2005-12-22 | 2015-09-15 | Qualcomm Incorporated | Methods and apparatus for communicating control information |
| US8514771B2 (en) | 2005-12-22 | 2013-08-20 | Qualcomm Incorporated | Methods and apparatus for communicating and/or using transmission power information |
| US9125093B2 (en) | 2005-12-22 | 2015-09-01 | Qualcomm Incorporated | Methods and apparatus related to custom control channel reporting formats |
| US9125092B2 (en) | 2005-12-22 | 2015-09-01 | Qualcomm Incorporated | Methods and apparatus for reporting and/or using control information |
| US9572179B2 (en) | 2005-12-22 | 2017-02-14 | Qualcomm Incorporated | Methods and apparatus for communicating transmission backlog information |
| US8437251B2 (en) | 2005-12-22 | 2013-05-07 | Qualcomm Incorporated | Methods and apparatus for communicating transmission backlog information |
| US20070253449A1 (en) | 2005-12-22 | 2007-11-01 | Arnab Das | Methods and apparatus related to determining, communicating, and/or using delay information |
| US20070243882A1 (en) | 2006-04-12 | 2007-10-18 | Qualcomm Incorporated | Method and apparatus for locating a wireless local area network associated with a wireless wide area network |
| JP5051471B2 (ja) * | 2006-08-31 | 2012-10-17 | 智 板見 | 休止期脱毛症治療剤 |
| AU2008219633B2 (en) * | 2007-02-28 | 2011-05-26 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Method for alleviating side effects of retinoic acid therapy and/or improving efficacy without interfering with efficacy |
| AU2011204425A1 (en) | 2010-01-11 | 2012-08-02 | Healor Ltd. | Method for treatment of inflammatory disease and disorder |
| JP7229772B2 (ja) * | 2016-04-22 | 2023-02-28 | ジェイシー(ウーシー) カンパニー,インコーポレーテッド | イソチオシアネート系化合物の使用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4505896A (en) * | 1979-04-19 | 1985-03-19 | Elorac, Ltd. | Method of treating acne vulgaris and composition |
| DE3110611A1 (de) * | 1981-03-18 | 1982-10-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | "mitogene der leukozyten und des entzuendungsgewebes:natuerliche leukopoetine zur selektiven anregung der teilung und differenzierung von leukozyten" |
| GB8330969D0 (en) * | 1983-11-21 | 1983-12-29 | Wellcome Found | Promoting healing |
| DE3570598D1 (en) * | 1984-11-15 | 1989-07-06 | Nitto Denko Corp | Composition for percutaneous administration |
| US4965252A (en) * | 1988-06-28 | 1990-10-23 | Hauser-Kuhrts, Inc. | Cholesterol-lowering combination compositions of guar gum and niacin |
| EP0573568B1 (en) * | 1991-03-01 | 2001-01-24 | University Of Florida Research Foundation, Inc. | Use of nicotinic analogs for treatment of degenerative diseases of the nervous system |
| US5240945A (en) * | 1992-02-18 | 1993-08-31 | Warshaw Thelma G | Method and compositions for treating acne |
| US5496827A (en) * | 1994-07-15 | 1996-03-05 | Patrick; Jay | Compositions for the transdermal delivery of nutrients |
| US5612382A (en) * | 1994-07-15 | 1997-03-18 | Frances B. Fike | Composition for percutaneous absorption of pharmaceutically active ingredients |
| WO1996029405A2 (en) * | 1995-03-20 | 1996-09-26 | Ligand Pharmaceuticals Incorporated | MODULATORS OF ob GENE AND SCREENING METHODS THEREFOR |
| JP4553166B2 (ja) * | 1995-05-01 | 2010-09-29 | スカリスタ リミテッド | ニコチン酸エステルおよびそれを含む薬剤組成物 |
| US20040102358A1 (en) * | 1997-05-19 | 2004-05-27 | Scivoletto Rosemarie | Composition for treating skin conditions |
| AU4672199A (en) * | 1998-05-20 | 1999-12-06 | Yale University | Modulation of angiogenesis and wound healing |
| NZ511708A (en) * | 1998-12-01 | 2003-12-19 | Univ Kentucky Res Found | A method for enhancing protective cellular responses to genotoxic stress in skin |
| IT1306141B1 (it) * | 1999-05-17 | 2001-05-30 | Giampiero Valletta | Composizione per il trattamento del prurito uremico e di forme diprurito non riconducibili a lesioni organiche. |
| US6326034B1 (en) * | 1999-12-22 | 2001-12-04 | Natural Compounds Ltd | Natural extracted and synthetic antioxidant compositions |
| WO2002072092A1 (en) * | 2001-03-08 | 2002-09-19 | University Of Kentucky | Method for increasing leptin levels using nicotinic acid compounds |
-
2002
- 2002-03-08 WO PCT/US2002/007256 patent/WO2002072092A1/en not_active Ceased
- 2002-03-08 MX MXPA03008096A patent/MXPA03008096A/es active IP Right Grant
- 2002-03-08 DE DE60229041T patent/DE60229041D1/de not_active Expired - Lifetime
- 2002-03-08 PT PT02721337T patent/PT1365762E/pt unknown
- 2002-03-08 JP JP2002571051A patent/JP5057353B2/ja not_active Expired - Fee Related
- 2002-03-08 EP EP02721337A patent/EP1365762B1/en not_active Expired - Lifetime
- 2002-03-08 AT AT02721337T patent/ATE409037T1/de active
- 2002-03-08 CN CNB028061209A patent/CN1265792C/zh not_active Expired - Fee Related
- 2002-03-08 US US10/094,063 patent/US6750234B2/en not_active Expired - Lifetime
- 2002-03-08 DK DK02721337T patent/DK1365762T3/da active
- 2002-03-08 ES ES02721337T patent/ES2315358T3/es not_active Expired - Lifetime
- 2002-03-08 CA CA002437844A patent/CA2437844C/en not_active Expired - Lifetime
-
2004
- 2004-04-14 US US10/825,405 patent/US20040198776A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2437844A1 (en) | 2002-09-19 |
| US20020128298A1 (en) | 2002-09-12 |
| US20040198776A1 (en) | 2004-10-07 |
| HK1065941A1 (en) | 2005-03-11 |
| ATE409037T1 (de) | 2008-10-15 |
| MXPA03008096A (es) | 2005-10-05 |
| ES2315358T3 (es) | 2009-04-01 |
| CN1265792C (zh) | 2006-07-26 |
| WO2002072092A1 (en) | 2002-09-19 |
| DE60229041D1 (de) | 2008-11-06 |
| EP1365762B1 (en) | 2008-09-24 |
| US6750234B2 (en) | 2004-06-15 |
| CN1496260A (zh) | 2004-05-12 |
| JP2004519488A (ja) | 2004-07-02 |
| CA2437844C (en) | 2007-05-15 |
| EP1365762A1 (en) | 2003-12-03 |
| EP1365762A4 (en) | 2005-05-25 |
| DK1365762T3 (da) | 2008-11-17 |
| JP5057353B2 (ja) | 2012-10-24 |
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