[go: up one dir, main page]

PT1161530E - Proteina para bloquear a adesao de plaquetas - Google Patents

Proteina para bloquear a adesao de plaquetas

Info

Publication number
PT1161530E
PT1161530E PT00909351T PT00909351T PT1161530E PT 1161530 E PT1161530 E PT 1161530E PT 00909351 T PT00909351 T PT 00909351T PT 00909351 T PT00909351 T PT 00909351T PT 1161530 E PT1161530 E PT 1161530E
Authority
PT
Portugal
Prior art keywords
protein
block plate
plate adhesion
adhesion
block
Prior art date
Application number
PT00909351T
Other languages
English (en)
Inventor
Wolfgang Strittmatter
Detlef Guessow
Uwe Hofmann
Juergen Hemberger
Zisi Fotev
Bernhard Scheuble
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PT1161530E publication Critical patent/PT1161530E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT00909351T 1999-03-18 2000-03-10 Proteina para bloquear a adesao de plaquetas PT1161530E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99105530 1999-03-18
EP99109503 1999-05-12
PCT/EP2000/002117 WO2000056885A1 (en) 1999-03-18 2000-03-10 Protein for blocking platelet adhesion

Publications (1)

Publication Number Publication Date
PT1161530E true PT1161530E (pt) 2005-09-30

Family

ID=26152935

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00909351T PT1161530E (pt) 1999-03-18 2000-03-10 Proteina para bloquear a adesao de plaquetas

Country Status (27)

Country Link
US (3) US6774107B1 (pt)
EP (1) EP1161530B1 (pt)
JP (1) JP4805461B2 (pt)
KR (1) KR100788219B1 (pt)
CN (1) CN1185344C (pt)
AR (1) AR023099A1 (pt)
AT (1) ATE295883T1 (pt)
AU (1) AU767172B2 (pt)
BR (1) BR0009074A (pt)
CA (1) CA2367457C (pt)
CO (1) CO5241328A1 (pt)
CZ (1) CZ301524B6 (pt)
DE (1) DE60020220T2 (pt)
DK (1) DK1161530T3 (pt)
ES (1) ES2240067T3 (pt)
HK (1) HK1045330B (pt)
HU (1) HU228068B1 (pt)
MX (1) MXPA01009363A (pt)
MY (1) MY123371A (pt)
NO (1) NO330769B1 (pt)
PL (1) PL200384B1 (pt)
PT (1) PT1161530E (pt)
RU (1) RU2292351C2 (pt)
SI (1) SI1161530T1 (pt)
SK (1) SK287496B6 (pt)
TR (1) TR200102729T2 (pt)
WO (1) WO2000056885A1 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000056885A1 (en) * 1999-03-18 2000-09-28 Merck Patent Gmbh Protein for blocking platelet adhesion
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
JP2005511005A (ja) * 2001-07-18 2005-04-28 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング 糖タンパク質ｖｉ融合タンパク質
ATE430593T1 (de) 2003-10-28 2009-05-15 Medtronic Inc Verfahren zur herstellung von vernetzten materialien und bioprothetischen vorrichtungen
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
EP1799828B1 (en) * 2004-10-12 2013-05-01 Board of Trustees of Michigan State University Biosynthesis of phloroglucinol and preparation of 1,3-dihydroxybenzene therefrom
US8999370B2 (en) * 2005-05-26 2015-04-07 Thomas Jefferson University Method to treat and prevent posterior capsule opacification
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
US7691839B2 (en) 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20080015145A1 (en) * 2006-07-11 2008-01-17 Maria Gyongyossy-Issa Mimotope receptors and inhibitors for platelet-platelet and platelet-endothelium interactions
GB2460915B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor
KR101773551B1 (ko) 2008-10-15 2017-08-31 아이오니스 파마수티컬즈, 인코포레이티드 인자 １１ 발현의 조정
WO2012003461A2 (en) 2010-07-02 2012-01-05 Draths Corporation Phloroglucinol synthases and methods of making and using the same
WO2012006245A1 (en) 2010-07-06 2012-01-12 Draths Corporation Phloroglucinol reductase and methods of making and using the same
WO2012006244A1 (en) 2010-07-06 2012-01-12 Draths Corporation Method for producing phloroglucinol and dihydrophloroglucinol
ES2910305T3 (es) 2010-08-19 2022-05-12 Zoetis Belgium S A Anticuerpos anti-NGF y su uso
US8790651B2 (en) 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
DE202012012998U1 (de) 2011-08-31 2014-06-13 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
AU2013271564A1 (en) 2012-06-06 2014-12-04 Zoetis Services Llc Caninized anti-NGF antibodies and methods thereof
EP2875041A2 (en) 2012-07-19 2015-05-27 Zoetis LLC Bovine influenza c virus compositions
WO2014018724A1 (en) 2012-07-27 2014-01-30 Zoetis Llc Tick toxin compositions
CA3153265A1 (en) 2016-08-17 2018-02-22 Pharmaq As Sea lice vaccine
BR102017005783A2 (pt) 2017-03-21 2018-10-02 Fund Butantan processo de obtenção de esculptina e seus fragmentos, esculptina recombinante e seus usos
BR112020017701A2 (pt) 2018-03-12 2020-12-29 Zoetis Services Llc Anticorpos anti-ngf e métodos dos mesmos
EP3765069A1 (en) 2018-03-16 2021-01-20 Zoetis Services LLC Peptide vaccines against interleukin-31
CA3093539A1 (en) 2018-03-16 2019-09-19 Zoetis Services Llc Interleukin-31 monoclonal antibodies for veterinary use
MY204000A (en) 2018-05-09 2024-07-31 Ionis Pharmaceuticals Inc Compounds and methods for reducing fxi expression
BR112022004488A2 (pt) 2019-09-11 2022-05-31 Zoetis Services Llc Herpesvírus recombinante de vetores de peru que expressam antígenos de patógenos aviários e seus usos
US20220119513A1 (en) 2020-06-08 2022-04-21 Zoetis Services Llc Anti-tgfb antibodies and therapeutic uses thereof
US12440556B2 (en) 2020-06-15 2025-10-14 Zoetis Services Llc Genetically modified cell line for production of Marek's disease virus vaccine and methods of making and using the same
CN116568708A (zh) 2020-10-07 2023-08-08 硕腾服务有限责任公司 抗ngf抗体和其使用方法
CN116406378A (zh) 2020-10-19 2023-07-07 硕腾服务有限责任公司 犬和猫抑瘤素M受体β的抗体及其用途
JP2024534643A (ja) 2021-09-27 2024-09-20 ゾエティス・サービシーズ・エルエルシー 抗ＴＧＦβ１、２、３抗体及びその治療的使用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705355A (en) * 1984-03-27 1998-01-06 Transgene, S.A. Hirudin, pharmaceutical compositions comprising it and their use
US4898734A (en) 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
IL86857A (en) * 1988-06-24 1994-04-12 Yissum Res Dev Co Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same
US5182260A (en) * 1989-01-27 1993-01-26 Biogen, Inc. Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them
NZ237244A (en) * 1990-03-02 1992-10-28 Bio Technology General Corp Cloning and production of human von willebrand factor analogues and compositions thereof
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation
GB9022040D0 (en) * 1990-10-10 1990-11-21 Biopharm Ltd Platelet adhesion inhibitor
DE4136513A1 (de) * 1991-11-06 1993-05-13 Basf Ag Neues thrombininhibitorisches protein aus raubwanzen
KR100445309B1 (ko) * 1993-07-01 2004-11-12 메르크 파텐트 게엠베하 콜라겐-자극혈소판응집에대한억제제
EP1649853A3 (en) 1993-07-29 2006-11-22 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Microtubule stabilizing agents for treating atherosclerosis or restenosis
US5882887A (en) * 1994-09-12 1999-03-16 Schering Aktiengesellschaft Process for manufacture of a modified collagen-induced platelet aggregation inhibitor pallidipin
CA2203827A1 (en) * 1994-10-28 1996-05-09 Gerard Voerman Novel family of protease inhibitors, and other biologic active substances
WO2000056885A1 (en) 1999-03-18 2000-09-28 Merck Patent Gmbh Protein for blocking platelet adhesion
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen

Also Published As

Publication number Publication date
NO330769B1 (no) 2011-07-11
DK1161530T3 (da) 2005-08-08
US6962801B2 (en) 2005-11-08
HUP0200353A2 (hu) 2002-05-29
JP2002539788A (ja) 2002-11-26
RU2292351C2 (ru) 2007-01-27
CO5241328A1 (es) 2003-01-31
ES2240067T3 (es) 2005-10-16
HU228068B1 (en) 2012-09-28
CN1344318A (zh) 2002-04-10
AU767172B2 (en) 2003-11-06
PL350147A1 (en) 2002-11-04
HK1045330B (zh) 2005-09-09
SK12902001A3 (sk) 2002-03-05
DE60020220T2 (de) 2006-05-24
US20050065084A1 (en) 2005-03-24
NO20014506D0 (no) 2001-09-17
KR100788219B1 (ko) 2007-12-26
HK1045330A1 (en) 2002-11-22
NO20014506L (no) 2001-11-16
MXPA01009363A (es) 2002-06-04
BR0009074A (pt) 2002-01-02
US6774107B1 (en) 2004-08-10
SI1161530T1 (en) 2005-10-31
JP4805461B2 (ja) 2011-11-02
DE60020220D1 (de) 2005-06-23
WO2000056885A1 (en) 2000-09-28
HUP0200353A3 (en) 2003-12-29
EP1161530B1 (en) 2005-05-18
ATE295883T1 (de) 2005-06-15
KR20020008131A (ko) 2002-01-29
CA2367457A1 (en) 2000-09-28
TR200102729T2 (tr) 2002-04-22
US20060094079A1 (en) 2006-05-04
CZ301524B6 (cs) 2010-03-31
MY123371A (en) 2006-05-31
PL200384B1 (pl) 2008-12-31
CN1185344C (zh) 2005-01-19
CA2367457C (en) 2010-09-21
CZ20013341A3 (cs) 2002-01-16
AU3166200A (en) 2000-10-09
EP1161530A1 (en) 2001-12-12
AR023099A1 (es) 2002-09-04
SK287496B6 (sk) 2010-12-07
US7090986B2 (en) 2006-08-15

Similar Documents

Publication Publication Date Title
PT1161530E (pt) Proteina para bloquear a adesao de plaquetas
DE69926157D1 (de) Plattenverbindungsvorrichtungen
DE59900456D1 (de) Druckplattenzylinder
DE69819847D1 (de) Plattensystem
DE10083270D2 (de) Belagträgerplatte
PT904285E (pt) Inibidores de adesao ciclicos
FI990638L (fi) Jakotukki
DK1127983T3 (da) Pladevibrator
DE69819218D1 (de) Plattenrüttler
DE69907647D1 (de) Plattenschieber
DE69825481D1 (de) Plattengerät
ID25700A (id) Unit penggerak piringan
DE60132579D1 (de) Raupenplatte
DE69821556D1 (de) Ventilblock
DE59901954D1 (de) Fünfzylinderoffsetdruckeinheiten
DE59909685D1 (de) Plattenventil
DE50015688D1 (de) Pflastersteinsystem
DE59901956D1 (de) Zehnzylinderoffsetdruckeinheiten
DE50013313D1 (de) Verdampferplatine
NO996125D0 (no) Roerpressforbindelse
NO20012133L (no) Smertestillende kur
FR2794092B1 (fr) Maitre-cylindre
ATA117397A (de) Kunststoffplatte
DE69826429D1 (de) Zylinderblockaufbau
DE50015729D1 (de) Exzenterpresse