PT1030667E - Utilizacao de mirtazapina para o fabrico de um medicamento para o tratamento de apenas do sono - Google Patents
Utilizacao de mirtazapina para o fabrico de um medicamento para o tratamento de apenas do sonoInfo
- Publication number
- PT1030667E PT1030667E PT98962348T PT98962348T PT1030667E PT 1030667 E PT1030667 E PT 1030667E PT 98962348 T PT98962348 T PT 98962348T PT 98962348 T PT98962348 T PT 98962348T PT 1030667 E PT1030667 E PT 1030667E
- Authority
- PT
- Portugal
- Prior art keywords
- mirtazapine
- sleep
- drug
- manufacture
- treatment
- Prior art date
Links
- RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001785 mirtazapine Drugs 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- RTHCYVBBDHJXIQ-UHFFFAOYSA-N N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine Chemical compound C=1C=CC=CC=1C(CCNC)OC1=CC=C(C(F)(F)F)C=C1 RTHCYVBBDHJXIQ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960002464 fluoxetine Drugs 0.000 abstract 1
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 abstract 1
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 abstract 1
- 201000002859 sleep apnea Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97203548 | 1997-11-14 | ||
| PCT/EP1998/007330 WO1999025356A1 (en) | 1997-11-14 | 1998-11-13 | Use of mirtazapine for treating sleep apneas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1030667E true PT1030667E (pt) | 2005-06-30 |
Family
ID=8228923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98962348T PT1030667E (pt) | 1997-11-14 | 1998-11-13 | Utilizacao de mirtazapina para o fabrico de um medicamento para o tratamento de apenas do sono |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6303595B1 (pt) |
| EP (1) | EP1030667B1 (pt) |
| JP (1) | JP2001522891A (pt) |
| KR (1) | KR20010032009A (pt) |
| CN (1) | CN1154495C (pt) |
| AT (1) | ATE289816T1 (pt) |
| AU (1) | AU737590B2 (pt) |
| BR (1) | BR9815098A (pt) |
| CA (1) | CA2309744A1 (pt) |
| CZ (1) | CZ296282B6 (pt) |
| DE (1) | DE69829202T2 (pt) |
| DK (1) | DK1030667T3 (pt) |
| ES (1) | ES2238781T3 (pt) |
| HU (1) | HUP0100080A3 (pt) |
| IL (2) | IL135825A0 (pt) |
| NO (1) | NO20002218L (pt) |
| PL (1) | PL192272B1 (pt) |
| PT (1) | PT1030667E (pt) |
| TR (1) | TR200001293T2 (pt) |
| WO (1) | WO1999025356A1 (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060241164A1 (en) * | 1998-02-27 | 2006-10-26 | The Board Of Trustees Of The University Of Illinoi | Pharmacological treatment for sleep apnea |
| ATE324110T1 (de) | 1998-02-27 | 2006-05-15 | Univ Illinois | Stoffe mit serotoninartiger wirkung zur behandlung der schlafapnoe |
| US7160898B2 (en) * | 2001-12-14 | 2007-01-09 | Board Of Trustees Of The University Of Illinois | Pharmacological treatment for sleep apnea |
| IL150290A0 (en) * | 2000-02-11 | 2002-12-01 | Akzo Nobel Nv | The use of mirtazapine for the treatment of sleep disorders |
| US20020183306A1 (en) * | 2001-05-30 | 2002-12-05 | Pfizer Inc. | Combination treatment for sleep disorders including sleep apnea |
| UA83666C2 (ru) | 2003-07-10 | 2008-08-11 | Н.В. Органон | Способ получения энантиомерно чистого миртазапина |
| US7838029B1 (en) | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
| EP1667972B1 (en) | 2003-09-10 | 2013-06-19 | Brentwood Equities Ltd. | Diastereomers of 4-aryloxy-3-hydroxypiperidines |
| WO2006023702A2 (en) * | 2004-08-20 | 2006-03-02 | Cypress Bioscience, Inc. | Method for treating sleep related breathing disorders with setiptiline |
| US20060122127A1 (en) * | 2004-11-17 | 2006-06-08 | Cypress Bioscience, Inc. | Methods for reducing the side effects associated with mirtzapine treatment |
| CN101132777A (zh) * | 2004-12-20 | 2008-02-27 | 科利吉姆制药公司 | 用于睡眠障碍的药物组合物 |
| EP2146993B1 (en) | 2007-04-11 | 2015-08-05 | Merck Sharp & Dohme B.V. | A method for the preparation of mirtazapine |
| WO2008157094A1 (en) * | 2007-06-13 | 2008-12-24 | Cypress Bioscience, Inc. | Improving the tolerability of mirtazapine and a second active by using them in combination |
| WO2013188806A1 (en) * | 2012-06-14 | 2013-12-19 | The Regents Of The University Of Michigan | Sleep apnea treatment |
| PT3261645T (pt) | 2015-02-27 | 2021-06-17 | Dechra Ltd | Estimulação do apetite, gestão da perda de peso, e tratamento da anorexia em cães e gatos |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
| EP0517984A1 (en) * | 1991-06-11 | 1992-12-16 | Merrell Dow Pharmaceuticals Inc. | Derivatives of amide analogs of certain methano bridged quinolizines |
| US5968932A (en) * | 1995-10-24 | 1999-10-19 | Gruenenthal Gmbh | Method of inhibiting sleep apnea |
| SE9504537D0 (sv) * | 1995-12-19 | 1995-12-19 | Jan Hedner | Sätt att behandla och diagnosticera andningsstörningar under sömn och medel för utförande av sättet |
| IL121076A (en) * | 1996-06-19 | 2000-10-31 | Akzo Nobel Nv | Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors |
| US6117855A (en) * | 1996-10-07 | 2000-09-12 | Merck Sharp & Dohme Ltd. | Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent |
-
1998
- 1998-11-13 CZ CZ20001751A patent/CZ296282B6/cs not_active IP Right Cessation
- 1998-11-13 JP JP2000520789A patent/JP2001522891A/ja active Pending
- 1998-11-13 WO PCT/EP1998/007330 patent/WO1999025356A1/en not_active Ceased
- 1998-11-13 US US09/554,143 patent/US6303595B1/en not_active Expired - Fee Related
- 1998-11-13 AU AU17548/99A patent/AU737590B2/en not_active Ceased
- 1998-11-13 DK DK98962348T patent/DK1030667T3/da active
- 1998-11-13 PT PT98962348T patent/PT1030667E/pt unknown
- 1998-11-13 ES ES98962348T patent/ES2238781T3/es not_active Expired - Lifetime
- 1998-11-13 DE DE69829202T patent/DE69829202T2/de not_active Expired - Fee Related
- 1998-11-13 HU HU0100080A patent/HUP0100080A3/hu unknown
- 1998-11-13 PL PL340467A patent/PL192272B1/pl not_active IP Right Cessation
- 1998-11-13 EP EP98962348A patent/EP1030667B1/en not_active Expired - Lifetime
- 1998-11-13 BR BR9815098-7A patent/BR9815098A/pt not_active Application Discontinuation
- 1998-11-13 AT AT98962348T patent/ATE289816T1/de not_active IP Right Cessation
- 1998-11-13 CA CA002309744A patent/CA2309744A1/en not_active Abandoned
- 1998-11-13 IL IL13582598A patent/IL135825A0/xx active IP Right Grant
- 1998-11-13 CN CNB988111349A patent/CN1154495C/zh not_active Expired - Fee Related
- 1998-11-13 KR KR1020007005121A patent/KR20010032009A/ko not_active Ceased
- 1998-11-13 TR TR2000/01293T patent/TR200001293T2/xx unknown
-
2000
- 2000-04-25 IL IL135825A patent/IL135825A/en not_active IP Right Cessation
- 2000-04-28 NO NO20002218A patent/NO20002218L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001522891A (ja) | 2001-11-20 |
| PL340467A1 (en) | 2001-02-12 |
| NO20002218L (no) | 2000-05-12 |
| HK1029932A1 (en) | 2001-04-20 |
| PL192272B1 (pl) | 2006-09-29 |
| US6303595B1 (en) | 2001-10-16 |
| DK1030667T3 (da) | 2005-06-20 |
| IL135825A (en) | 2006-12-31 |
| EP1030667B1 (en) | 2005-03-02 |
| CA2309744A1 (en) | 1999-05-27 |
| ES2238781T3 (es) | 2005-09-01 |
| TR200001293T2 (tr) | 2002-09-23 |
| ATE289816T1 (de) | 2005-03-15 |
| HUP0100080A2 (hu) | 2001-08-28 |
| CN1278731A (zh) | 2001-01-03 |
| EP1030667A1 (en) | 2000-08-30 |
| CZ296282B6 (cs) | 2006-02-15 |
| WO1999025356A1 (en) | 1999-05-27 |
| AU1754899A (en) | 1999-06-07 |
| AU737590B2 (en) | 2001-08-23 |
| CN1154495C (zh) | 2004-06-23 |
| DE69829202T2 (de) | 2005-07-21 |
| BR9815098A (pt) | 2000-10-10 |
| KR20010032009A (ko) | 2001-04-16 |
| NO20002218D0 (no) | 2000-04-28 |
| HUP0100080A3 (en) | 2002-05-28 |
| DE69829202D1 (de) | 2005-04-07 |
| IL135825A0 (en) | 2001-05-20 |
| CZ20001751A3 (cs) | 2000-10-11 |
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