PT1066027E - PHARMACEUTICAL COMPOSITION OF TOPIRAMATO - Google Patents

PHARMACEUTICAL COMPOSITION OF TOPIRAMATO

Info

Publication number: PT1066027E
Authority: PT; Portugal
Prior art keywords: topiramato; pharmaceutical composition; pharmaceutical; composition
Prior art date: 1998-03-04

Application number

PT99908594T

Other languages

Portuguese (pt)

Inventor

Pramod M Kotwal

Madhav S Thakur

Irwin S Gibbs

Original Assignee

Ortho Mcneil Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-04

Filing date

1999-03-01

Publication date

2003-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22134079&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1066027(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-03-01 Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc

2003-12-31 Publication of PT1066027E publication Critical patent/PT1066027E/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pain & Pain Management (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PT99908594T 1998-03-04 1999-03-01 PHARMACEUTICAL COMPOSITION OF TOPIRAMATO PT1066027E (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7677098P	1998-03-04	1998-03-04

Publications (1)

Publication Number	Publication Date
PT1066027E true PT1066027E (en)	2003-12-31

Family

ID=22134079

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT99908594T PT1066027E (en)	1998-03-04	1999-03-01	PHARMACEUTICAL COMPOSITION OF TOPIRAMATO

Country Status (31)

Country	Link
US (4)	US6696091B2 (en)
EP (1)	EP1066027B1 (en)
JP (1)	JP2003530295A (en)
KR (1)	KR20010041592A (en)
CN (1)	CN100364501C (en)
AR (3)	AR017984A1 (en)
AT (1)	ATE246490T1 (en)
AU (1)	AU763643B2 (en)
BG (1)	BG64885B1 (en)
BR (1)	BR9908488A (en)
CA (1)	CA2322644C (en)
DE (1)	DE69910186T2 (en)
DK (1)	DK1066027T3 (en)
EA (1)	EA200000814A1 (en)
EE (1)	EE04175B1 (en)
ES (1)	ES2204109T3 (en)
HR (1)	HRP20000563B1 (en)
HU (1)	HUP0301192A3 (en)
ID (1)	ID26982A (en)
IL (2)	IL138032A0 (en)
MY (1)	MY125821A (en)
NO (1)	NO20004311L (en)
NZ (1)	NZ506532A (en)
PL (1)	PL194559B1 (en)
PT (1)	PT1066027E (en)
SK (1)	SK285440B6 (en)
TR (1)	TR200002541T2 (en)
TW (1)	TW590778B (en)
UA (1)	UA65607C2 (en)
WO (1)	WO1999044581A2 (en)
ZA (1)	ZA991716B (en)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6099865A (en) *	1998-07-08	2000-08-08	Fmc Corporation	Croscarmellose taste masking
DK1158950T3 (en)	1999-02-17	2006-04-24	Ortho Mcneil Pharm Inc	anticonvulsant derivatives for the treatment of essential tremor
NZ514811A (en) *	1999-04-08	2005-01-28	Ortho Mcneil Pharm Inc	Anticonvulsant derivatives useful in reducing blood glucose levels
ES2542892T3 (en) *	1999-06-14	2015-08-12	Vivus, Inc.	Combination therapy for the treatment of hypertension associated with obesity
EP1157682A1 (en) *	2000-05-25	2001-11-28	Cilag AG	Blister package for topiramate tablets
PL365680A1 (en) *	2000-07-07	2005-01-10	Ortho-Mcneil Pharmaceutical, Inc.	Anticonvulsant derivatives useful for preventing the development of type ii diabetes mellitus and syndrome x
ES2269297T3 (en) *	2000-10-30	2007-04-01	Ortho-Mcneil Pharmaceutical, Inc.	THERAPEUTIC COMBINATION CONTAINING ANTIDIABETIC AND ANTICONVULSIVE AGENTS.
US7771749B2 (en)	2001-07-11	2010-08-10	Monsanto Technology Llc	Lignin-based microparticles for the controlled release of agricultural actives
US20070281003A1 (en)	2001-10-12	2007-12-06	Fuisz Richard C	Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8603514B2 (en)	2002-04-11	2013-12-10	Monosol Rx, Llc	Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US10285910B2 (en)	2001-10-12	2019-05-14	Aquestive Therapeutics, Inc.	Sublingual and buccal film compositions
US8900497B2 (en)	2001-10-12	2014-12-02	Monosol Rx, Llc	Process for making a film having a substantially uniform distribution of components
US7357891B2 (en)	2001-10-12	2008-04-15	Monosol Rx, Llc	Process for making an ingestible film
US11207805B2 (en)	2001-10-12	2021-12-28	Aquestive Therapeutics, Inc.	Process for manufacturing a resulting pharmaceutical film
US20110033542A1 (en)	2009-08-07	2011-02-10	Monosol Rx, Llc	Sublingual and buccal film compositions
US8900498B2 (en)	2001-10-12	2014-12-02	Monosol Rx, Llc	Process for manufacturing a resulting multi-layer pharmaceutical film
US20190328679A1 (en)	2001-10-12	2019-10-31	Aquestive Therapeutics, Inc.	Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8765167B2 (en)	2001-10-12	2014-07-01	Monosol Rx, Llc	Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20050175690A1 (en) *	2003-12-29	2005-08-11	David Edgren	Novel drug compositions and dosage forms
US20050232995A1 (en)	2002-07-29	2005-10-20	Yam Nyomi V	Methods and dosage forms for controlled delivery of paliperidone and risperidone
JP2005536568A (en) *	2002-07-29	2005-12-02	アルザ・コーポレーシヨン	Formulations and dosage forms for the controlled distribution of topiramate
CN1726027A (en) *	2002-12-13	2006-01-25	西拉格股份公司	Controlled release formulation comprising tramadol and topiramate
EP1587499A1 (en) *	2003-01-31	2005-10-26	Elan Pharma International Limited	Nanoparticulate topiramate formulations
ITMI20031096A1 (en) *	2003-05-30	2004-11-30	Eurand Spa	MICROCAPS FOR COACERVATION CONTAINING DRUG INCORPORATED IN THE COATING POLYMER
US6949518B1 (en)	2003-06-25	2005-09-27	Pao-Hsien Chu	Methods for treating macular degeneration with topiramate
WO2005020961A1 (en) *	2003-08-28	2005-03-10	Sandoz Ag	Pharmaceutical composition comprising anticonvulsant with taste mask coating
EP1701697A2 (en) *	2003-09-02	2006-09-20	ALZA Corporation	Novel drug compositions and dosage forms of topiramate
JP4808392B2 (en) *	2003-09-04	2011-11-02	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Pharmacological composition concealing bitterness
MXPA06006586A (en) *	2003-12-09	2007-02-21	Pharmasset Inc	DOSING METHODS FOR ß-D-2aCO,3aCO-DIDEOXY-2aCO,3aCO-DIDEHYDRO-5-FLUOROCYTIDINE ANTIVIRAL THERAPY.
WO2005065648A2 (en) *	2003-12-29	2005-07-21	Alza Corporation, Inc.,	Novel drug compositions and dosage forms of topiramate
JP2007517062A (en) *	2003-12-29	2007-06-28	アルザ・コーポレーシヨン	Coating of drug granules giving adhesion resistance during mechanical compression
MY147767A (en)	2004-06-16	2013-01-31	Janssen Pharmaceutica Nv	Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
MX2007014613A (en)	2005-05-20	2008-04-02	Johnson & Johnson	Process for preparation of sulfamide derivatives.
WO2007002009A2 (en) *	2005-06-20	2007-01-04	Johnson & Johnson	Product authentication
US8247018B2 (en) *	2005-06-20	2012-08-21	Authentiform Technologies, Llc	Methods for quality control
US7874489B2 (en) *	2005-06-20	2011-01-25	Authentiform Technologies, Llc	Product authentication
CA2521272A1 (en) *	2005-10-04	2007-04-04	Bernard Charles Sherman	Capsules comprising topiramate
AR058389A1 (en)	2005-12-19	2008-01-30	Janssen Pharmaceutica Nv	USE OF SULFAMIDE BENZO-FUSED HETEROCICLIC DERIVATIVES FOR THE TREATMENT OF OBESITY
US8691867B2 (en)	2005-12-19	2014-04-08	Janssen Pharmaceutica Nv	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8937096B2 (en)	2005-12-19	2015-01-20	Janssen Pharmaceutica Nv	Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8497298B2 (en)	2005-12-19	2013-07-30	Janssen Pharmaceutica Nv	Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8716231B2 (en)	2005-12-19	2014-05-06	Janssen Pharmaceutica Nv	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
EP2026790A2 (en)	2006-05-19	2009-02-25	Janssen Pharmaceutica, N.V.	Co-therapy for the treatment of epilepsy and related disorders
WO2008027557A2 (en) *	2006-08-31	2008-03-06	Spherics, Inc.	Topiramate compositions and methods of enhancing its bioavailability
US20090239942A1 (en) *	2006-09-15	2009-09-24	Cloyd James C	Topiramate Compositions and Methods of Making and Using the Same
WO2008034040A1 (en) *	2006-09-15	2008-03-20	Regents Of The University Of Minnesota	Topiramate compositions and methods for their use
EP1973528B1 (en)	2006-11-17	2012-11-07	Supernus Pharmaceuticals, Inc.	Sustained-release formulations of topiramate
WO2008070670A2 (en) *	2006-12-04	2008-06-12	Supernus Pharmaceuticals, Inc.	Enhanced immediate release formulations of topiramate
US8895061B2 (en) *	2007-03-02	2014-11-25	Meda Pharmaceuticals Inc.	Compositions comprising carisoprodol and methods of use thereof
CN101677958A (en) *	2007-03-26	2010-03-24	帝国制药株式会社	Oral pharmaceutical formulations for colon-specific delivery
JP5424571B2 (en) *	2007-04-12	2014-02-26	協和発酵キリン株式会社	Topiramate-containing solid preparation
US20090076128A1 (en) *	2007-09-15	2009-03-19	Protia Llc	Deuterium-enriched topiramate
WO2010008776A2 (en)	2008-06-23	2010-01-21	Janssen Pharmaceutica Nv	Disposable patch and reusable sensor assembly for use in medical device localization and mapping systems
US8815939B2 (en)	2008-07-22	2014-08-26	Janssen Pharmaceutica Nv	Substituted sulfamide derivatives
JP6133009B2 (en) *	2010-08-11	2017-05-24	協和発酵キリン株式会社	Topiramate granules
JP4803686B2 (en) *	2010-08-31	2011-10-26	協和発酵キリン株式会社	Granules and orally disintegrating tablets containing a bitter-tasting drug
US9149959B2 (en)	2010-10-22	2015-10-06	Monosol Rx, Llc	Manufacturing of small film strips
US9457008B2 (en)	2012-03-23	2016-10-04	Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China	Joint product comprising synephrine and topiramate
CN103316026B (en)	2012-03-23	2016-05-11	中国人民解放军军事医学科学院毒物药物研究所	Contain joint product of Phentermine and Topiramate and preparation method thereof
CN102579367B (en) *	2012-03-23	2014-03-12	中国人民解放军军事医学科学院毒物药物研究所	Topiramate sustained-release drug composition, method for preparing same and application of Topiramate sustained-release drug composition
WO2014070958A1 (en)	2012-10-30	2014-05-08	Certirx Corporation	Product, image, or document authentication, verification, and item identification
JP6062077B2 (en) *	2013-03-12	2017-01-18	バイオ−ファームソリューションズカンパニーリミテッド	Phenylcarbamate compound for prevention or treatment of childhood epilepsy and epilepsy-related disease group {PHENYLCARBAMATECOMPOUNDSFORPREENTINGINGRETATINGINGPEDIATRICEPIANDYANDEPILESY-RELATEDSYNDROMES}
US8652527B1 (en) *	2013-03-13	2014-02-18	Upsher-Smith Laboratories, Inc	Extended-release topiramate capsules
ES2761407T3 (en)	2013-03-15	2020-05-19	Aprecia Pharmaceuticals LLC	Quickly dispersible topiramate dosage form
US9101545B2 (en)	2013-03-15	2015-08-11	Upsher-Smith Laboratories, Inc.	Extended-release topiramate capsules
WO2014167439A1 (en) *	2013-03-26	2014-10-16	Wockhardt Limited	Modified release pharmaceutical compositions of topiramate or salts thereof
US20160128943A1 (en) *	2013-06-04	2016-05-12	KVK-Tech, Inc.	Controlled release caffeine dosage forms
CN104922075A (en) *	2015-05-31	2015-09-23	黑龙江佰彤儿童药物研究有限公司	Solid preparation for treating pediatric epilepsy and preparation method thereof
US20170312223A1 (en) *	2016-05-02	2017-11-02	Sun Pharmaceutical Industries Limited	Sprinkle Composition of Cinacalcet
KR20230137362A (en)	2016-05-05	2023-10-04	어퀘스티브 테라퓨틱스, 아이엔씨.	Enhanced delivery epinephrine compositions
US11273131B2 (en)	2016-05-05	2022-03-15	Aquestive Therapeutics, Inc.	Pharmaceutical compositions with enhanced permeation
US12427121B2 (en)	2016-05-05	2025-09-30	Aquestive Therapeutics, Inc.	Enhanced delivery epinephrine compositions
US12433850B2 (en)	2016-05-05	2025-10-07	Aquestive Therapeutics, Inc.	Enhanced delivery epinephrine and prodrug compositions
WO2020104837A1 (en)	2018-11-21	2020-05-28	Rosemont Pharmaceuticals Limited	Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability
WO2023076281A1 (en)	2021-10-25	2023-05-04	Aquestive Therapeutics, Inc.	Oral and nasal compositions and methods of treatment

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1509866A (en)	1975-06-10	1978-05-04	Johnson & Johnson	Enteric coated digestive enzyme compositions
DD146547A5 (en)	1978-07-15	1981-02-18	Boehringer Sohn Ingelheim	MEDICINAL RETARDANT SHAPE WITH UNFORGETTABLE POROESEN DIFFUSION SHELLS
US4205060A (en)	1978-12-20	1980-05-27	Pennwalt Corporation	Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use
DE3012136C2 (en)	1980-03-28	1984-02-16	Bauer, Kurt Heinz, Prof. Dr., 7800 Freiburg	Process for the production of a granulate
JPS5758631A (en) *	1980-09-24	1982-04-08	Toyo Jozo Co Ltd	Coating composition
EP0088635B1 (en) *	1982-03-10	1986-12-30	Toray Industries, Inc.	Laminated film and magnetic recording medium made therewith
US4994260A (en)	1982-05-28	1991-02-19	Astra Lakemedel Aktiebolag	Pharmaceutical mixture
US4505616A (en) *	1983-05-26	1985-03-19	Litton Systems, Inc.	Self-locking chock system for a jack-up rig unit
US4513006A (en) *	1983-09-26	1985-04-23	Mcneil Lab., Inc.	Anticonvulsant sulfamate derivatives
US4568559A (en)	1984-02-06	1986-02-04	Biotek, Inc.	Composite core coated microparticles and process of preparing same
GB8403359D0 (en)	1984-02-08	1984-03-14	Erba Farmitalia	Pharmaceutical compositions
GB8403361D0 (en)	1984-02-08	1984-03-14	Erba Farmitalia	Pharmaceutical composition
GB8403360D0 (en)	1984-02-08	1984-03-14	Erba Farmitalia	Pharmaceutical compositions
DE3405378A1 (en)	1984-02-15	1985-08-22	Röhm GmbH, 6100 Darmstadt	MEDICINE COVER
GB8414220D0 (en) *	1984-06-04	1984-07-11	Sterwin Ag	Medicaments in unit dose form
DE3440288C2 (en)	1984-11-05	1987-03-12	Gergely, Gerhard, Dr.-Ing., Wien	Pharmaceutical preparation containing ibuprofen and process for its preparation
IT1183574B (en)	1985-05-08	1987-10-22	Eurand Spa	METHOD FOR OBTAINING A HOMOGENEOUS ETHERPORARY SUSPENSION OF MICROCAPS
US5286489A (en)	1985-08-26	1994-02-15	The Procter & Gamble Company	Taste masking compositions
US4800087A (en)	1986-11-24	1989-01-24	Mehta Atul M	Taste-masked pharmaceutical compositions
JPS63188621A (en)	1987-01-30	1988-08-04	Taisho Pharmaceut Co Ltd	Flavor masking oral preparation
GB8702411D0 (en)	1987-02-03	1987-03-11	Zyma Sa	Swellable pellets
US4874613A (en) *	1987-03-06	1989-10-17	Baker Cummins Pharmaceuticals, Inc.	Taste concealing pharmaceutical dosage unit
DK130287D0 (en)	1987-03-13	1987-03-13	Benzon As Alfred	ORAL PREPARATION
FR2613619B1 (en)	1987-04-07	1993-10-15	Recherche Informatique Pharmacie	DRUGS, DIETETIC PRODUCTS OR HYGIENE PRODUCTS IN THE FORM OF POWDER COMPOSITIONS OBTAINED BY ADSORPTION OF ACTIVE INGREDIENTS ON A FAST-DISSOLVING SUGAR
US4994496A (en)	1987-09-09	1991-02-19	Repasky Elizabeth A	Use of milk globules as carriers for drugs
NZ226822A (en) *	1987-11-16	1990-03-27	Mcneil Consumer Prod	Chewable medicament tablet containing means for taste masking
US4851226A (en)	1987-11-16	1989-07-25	Mcneil Consumer Products Company	Chewable medicament tablet containing means for taste masking
US4851266A (en) *	1988-05-31	1989-07-25	Akira Momose	Surface treatment of powderfree surgical gloves
IT1226549B (en) *	1988-07-12	1991-01-24	Resa Farma	PHARMACEUTICAL COMPOSITIONS WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY FOR ORAL USE, EQUIPPED WITH EXCELLENT PALATABILITY AND FREE FROM IRRITATING EFFECTS ON MUCOSES.
US4916161A (en)	1988-10-25	1990-04-10	Bristol-Myers Squibb	Taste-masking pharmaceutical agents
US5013716A (en)	1988-10-28	1991-05-07	Warner-Lambert Company	Unpleasant taste masking compositions and methods for preparing same
IT1227899B (en)	1988-12-23	1991-05-14	Poli Ind Chimica Spa	TOTAL OR PARTIAL COATING OF PHARMACEUTICAL ACTIVE SUBSTANCES AND RELATED COMPOSITIONS
US5275823A (en)	1989-04-27	1994-01-04	Smith Kline & French Laboratories Ltd.	Pharmaceutical compositions
US5133974A (en) *	1989-05-05	1992-07-28	Kv Pharmaceutical Company	Extended release pharmaceutical formulations
US5084278A (en)	1989-06-02	1992-01-28	Nortec Development Associates, Inc.	Taste-masked pharmaceutical compositions
JP3317444B2 (en) *	1989-07-20	2002-08-26	大日本製薬株式会社	Immediate release formulation with unpleasant taste masked
US5417985A (en)	1989-07-20	1995-05-23	Farmalyoc	Solid and porous single dosage form comprising particles in the form of beads and its preparation
US5082669A (en)	1989-07-20	1992-01-21	Dainippon Pharmaceutical Co., Ltd.	Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked
NZ234587A (en)	1989-08-04	1991-11-26	Mcneil Ppc Inc	A chewable pharmaceutical tablet of compressed coated granules
DE3929166A1 (en) *	1989-09-02	1991-03-07	Basf Ag	METHOD FOR PRODUCING MAGNETIC RECORDING CARRIERS
US4958252A (en) *	1990-01-16	1990-09-18	Westinghouse Electric Corp.	Circuit breaker with rating plug having memory
US5206030A (en)	1990-02-26	1993-04-27	Fmc Corporation	Film-forming composition and use for coating pharmaceuticals, foods and the like
IT1241417B (en)	1990-03-06	1994-01-14	Vectorpharma Int	THERAPEUTIC COMPOSITIONS WITH CONTROLLED RELEASE OF DRUGS SUPPORTED ON CROSS-LINKED POLYMERS AND COATED WITH POLYMER FILM, AND THEIR PREPARATION PROCESS
FR2660317B1 (en)	1990-03-27	1994-01-14	Seppic	FILM-FORMING PRODUCT FOR COATING SOLID FORMS; ITS MANUFACTURING PROCESS AND PRODUCTS COATED WITH THIS PRODUCT.
IT1246383B (en)	1990-04-17	1994-11-18	Eurand Int	METHOD FOR MASKING THE TASTE OF DRUGS
US5075114A (en) *	1990-05-23	1991-12-24	Mcneil-Ppc, Inc.	Taste masking and sustained release coatings for pharmaceuticals
US5460825A (en)	1990-05-23	1995-10-24	Mcneil-Ppc, Inc.	Taste mask coatings for preparing chewable pharmaceutical tablets
CA2052679C (en) *	1990-08-30	1997-12-02	Edward J. Roche	Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5260072A (en) *	1990-08-30	1993-11-09	Mcneil-Ppc, Inc.	Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
CA2068402C (en)	1991-06-14	1998-09-22	Michael R. Hoy	Taste mask coatings for preparation of chewable pharmaceutical tablets
AU651244B2 (en) *	1991-09-19	1994-07-14	Mcneilab, Inc.	Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-0-(1-methylethylidene)-beta-D- fructopyranose and (1-methylcyclohexyl)methanol
DE4201179A1 (en)	1992-01-17	1993-07-22	Alfatec Pharma Gmbh	Granulates or pellets comprising dispersion of active agent in hydrophilic macromolecules - are e.g. for treatment of depression, hypertension, rheumatism, etc.
CA2137265C (en)	1992-06-04	2003-10-28	Sanjay Bhardwaj	Palatable pharmaceutical compositions
PH30929A (en)	1992-09-03	1997-12-23	Janssen Pharmaceutica Nv	Beads having a core coated with an antifungal and a polymer.
ATE175132T1 (en)	1992-10-26	1999-01-15	Sanol Arznei Schwarz Gmbh	METHOD FOR PRODUCING MICRO CAPSULES
GB9224855D0 (en) *	1992-11-27	1993-01-13	Smithkline Beecham Plc	Pharmaceutical compositions
US5354566A (en)	1993-06-02	1994-10-11	Kraft General Foods, Inc.	Preparation of yeast-leavened dough crusts
CA2164344C (en)	1993-08-30	2004-06-29	Stanley Lech	Tablet coating based on a melt-spun mixture of a saccharide and a polymer
US5425742A (en) *	1994-03-28	1995-06-20	Patrick S. Quigley	Use of hollow hypobaric chambers on body parts for increasing blood flow, reducing pressure and decreasing pain
SE9402422D0 (en) *	1994-07-08	1994-07-08	Astra Ab	New beads for controlled release and a pharmaceutical preparation containing the same
JPH0826977A (en) *	1994-07-19	1996-01-30	Tanabe Seiyaku Co Ltd	Controlled dissolution oral formulation
US5705183A (en)	1994-11-16	1998-01-06	Phillips Company	Cotton candy coated medication and a method for making and administering the same
US5560913A (en)	1995-01-27	1996-10-01	The Procter & Gamble Company	Pharmaceutical compositions
US5607697A (en) *	1995-06-07	1997-03-04	Cima Labs, Incorporated	Taste masking microparticles for oral dosage forms
US5795909A (en) *	1996-05-22	1998-08-18	Neuromedica, Inc.	DHA-pharmaceutical agent conjugates of taxanes
US5760007A (en) *	1997-07-16	1998-06-02	Ortho Pharmaceutical Corporation	Anticonvulsant derivatives useful in treating neuropathic pain

1999
- 1999-01-03 UA UA2000085074A patent/UA65607C2/en unknown
- 1999-03-01 EA EA200000814A patent/EA200000814A1/en unknown
- 1999-03-01 JP JP2000534184A patent/JP2003530295A/en active Pending
- 1999-03-01 TR TR2000/02541T patent/TR200002541T2/en unknown
- 1999-03-01 NZ NZ506532A patent/NZ506532A/en not_active IP Right Cessation
- 1999-03-01 DK DK99908594T patent/DK1066027T3/en active
- 1999-03-01 CA CA002322644A patent/CA2322644C/en not_active Expired - Lifetime
- 1999-03-01 PT PT99908594T patent/PT1066027E/en unknown
- 1999-03-01 MY MYPI99000735A patent/MY125821A/en unknown
- 1999-03-01 WO PCT/US1999/004449 patent/WO1999044581A2/en not_active Ceased
- 1999-03-01 ES ES99908594T patent/ES2204109T3/en not_active Expired - Lifetime
- 1999-03-01 DE DE69910186T patent/DE69910186T2/en not_active Revoked
- 1999-03-01 AT AT99908594T patent/ATE246490T1/en active
- 1999-03-01 SK SK1306-2000A patent/SK285440B6/en not_active IP Right Cessation
- 1999-03-01 HU HU0301192A patent/HUP0301192A3/en unknown
- 1999-03-01 US US09/259,718 patent/US6696091B2/en not_active Expired - Lifetime
- 1999-03-01 IL IL13803299A patent/IL138032A0/en active IP Right Grant
- 1999-03-01 EE EEP200000503A patent/EE04175B1/en unknown
- 1999-03-01 ID IDW20001690A patent/ID26982A/en unknown
- 1999-03-01 CN CNB998035890A patent/CN100364501C/en not_active Expired - Lifetime
- 1999-03-01 AU AU27989/99A patent/AU763643B2/en not_active Expired
- 1999-03-01 BR BR9908488-0A patent/BR9908488A/en not_active Application Discontinuation
- 1999-03-01 KR KR1020007009784A patent/KR20010041592A/en not_active Ceased
- 1999-03-01 PL PL99343894A patent/PL194559B1/en unknown
- 1999-03-01 HR HR20000563A patent/HRP20000563B1/en not_active IP Right Cessation
- 1999-03-01 EP EP99908594A patent/EP1066027B1/en not_active Revoked
- 1999-03-03 ZA ZA9901716A patent/ZA991716B/en unknown
- 1999-03-03 AR ARP990100895A patent/AR017984A1/en not_active Application Discontinuation
- 1999-03-26 TW TW088103263A patent/TW590778B/en not_active IP Right Cessation
2000
- 2000-08-23 IL IL138032A patent/IL138032A/en not_active IP Right Cessation
- 2000-08-29 BG BG104727A patent/BG64885B1/en unknown
- 2000-08-30 NO NO20004311A patent/NO20004311L/en unknown
2003
- 2003-12-30 US US10/748,764 patent/US7125560B2/en not_active Expired - Lifetime
2005
- 2005-03-31 AR ARP050101281A patent/AR048456A2/en not_active Application Discontinuation
- 2005-03-31 AR ARP050101282A patent/AR048457A2/en not_active Application Discontinuation
2006
- 2006-08-25 US US11/467,298 patent/US20060286163A1/en not_active Abandoned
2007
- 2007-10-30 US US11/927,850 patent/US20080260813A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AR017984A1 (en)	2001-10-24
JP2003530295A (en)	2003-10-14
HRP20000563B1 (en)	2009-07-31
NZ506532A (en)	2003-08-29
US20040156901A1 (en)	2004-08-12
BG104727A (en)	2001-05-31
ZA991716B (en)	2000-10-11
US6696091B2 (en)	2004-02-24
IL138032A0 (en)	2001-10-31
EE200000503A (en)	2002-02-15
EP1066027B1 (en)	2003-08-06
EP1066027A1 (en)	2001-01-10
US20020064563A1 (en)	2002-05-30
HUP0301192A3 (en)	2004-03-01
ATE246490T1 (en)	2003-08-15
WO1999044581A2 (en)	1999-09-10
TR200002541T2 (en)	2001-03-21
EE04175B1 (en)	2003-12-15
TW590778B (en)	2004-06-11
AU2798999A (en)	1999-09-20
DE69910186T2 (en)	2004-07-29
US20080260813A1 (en)	2008-10-23
DK1066027T3 (en)	2003-11-10
CN1419444A (en)	2003-05-21
PL194559B1 (en)	2007-06-29
UA65607C2 (en)	2004-04-15
HUP0301192A2 (en)	2003-08-28
US7125560B2 (en)	2006-10-24
IL138032A (en)	2007-09-20
BG64885B1 (en)	2006-08-31
HK1032009A1 (en)	2001-07-06
CN100364501C (en)	2008-01-30
CA2322644C (en)	2005-07-26
US20060286163A1 (en)	2006-12-21
EA200000814A1 (en)	2001-02-26
AR048456A2 (en)	2006-04-26
PL343894A1 (en)	2001-09-10
DE69910186D1 (en)	2003-09-11
NO20004311L (en)	2000-10-25
ES2204109T3 (en)	2004-04-16
WO1999044581A3 (en)	2003-07-17
NO20004311D0 (en)	2000-08-30
SK285440B6 (en)	2007-01-04
ID26982A (en)	2001-02-22
BR9908488A (en)	2000-12-05
MY125821A (en)	2006-08-30
AR048457A2 (en)	2006-04-26
AU763643B2 (en)	2003-07-31
SK13062000A3 (en)	2001-04-09
CA2322644A1 (en)	1999-09-10
KR20010041592A (en)	2001-05-25
HRP20000563A2 (en)	2001-04-30

Publication	Publication Date	Title
PT1066027E (en)	2003-12-31	PHARMACEUTICAL COMPOSITION OF TOPIRAMATO
PT945132E (en)	2004-08-31	COMPOSITION OF IBUPPHENE
ID27415A (en)	2001-04-05	PHARMACEUTICAL COMPOSITION
EA199900373A3 (en)	2000-08-28	PHARMACEUTICAL COMPOSITIONS
NO20005913D0 (en)	2000-11-22	Medicinal Composition
PT907364E (en)	2002-12-31	PHARMACEUTICAL COMPOSITION OF SUSTAINED LIBERTACAO
ID29021A (en)	2001-07-26	COMPOSITION OF CONTROLLED GALANTAMINA
DK1052974T3 (en)	2009-08-10	Pharmaceutical composition containing epothilone
PT892640E (en)	2004-06-30	PHARMACEUTICAL COMPOUNDS OF MYCOFENOLATE
ID29262A (en)	2001-08-16	PHARMACEUTICAL COMPOSITION
IS2325B (en)	2007-12-15	Microplated formulations of eplerone
ID22891A (en)	1999-12-16	PHARMACEUTICAL COMPOSITION FOR PIPERIDINOALANOL-DECONGESTANT COMBINATIONS
PT1014987E (en)	2004-06-30	ORAL COMPOSITIONS OF LEVOSIMENDANO
ID27201A (en)	2001-03-08	PHARMACEUTICAL COMPOSITION
FI991302L (en)	1999-06-08	Improved pharmaceutical compositions
ID29294A (en)	2001-08-16	PHARMACEUTICAL COMPOSITION
PT1227817E (en)	2004-11-30	AQUOSA PHARMACEUTICAL COMPOSITION CYCLOSONIDE CONTAINING
ID18698A (en)	1998-04-30	PHARMACEUTICAL COMPOSITION
ID25857A (en)	2000-11-09	PHARMACEUTICAL COMPOSITION
ID26215A (en)	2000-12-07	PHARMACEUTICAL COMPOSITION
ITMI962628A0 (en)	1996-12-16	PHARMACEUTICAL COMPOSITION
ID23531A (en)	2000-04-27	PHARMACEUTICAL COMPOSITION
ID23032A (en)	2000-01-06	COMPOSITION OF INSECTICIDE
SE9800330D0 (en)	1998-02-05	Pharmaceutical compositions
SE9800052D0 (en)	1998-01-13	Pharmaceutical compositions