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PL4180523T3 - Nowy wariant syntazy gmp hydrolizującej glutaminę i sposób wytwarzania nukleotydów purynowych z jego użyciem - Google Patents

Nowy wariant syntazy gmp hydrolizującej glutaminę i sposób wytwarzania nukleotydów purynowych z jego użyciem

Info

Publication number
PL4180523T3
PL4180523T3 PL21921687.6T PL21921687T PL4180523T3 PL 4180523 T3 PL4180523 T3 PL 4180523T3 PL 21921687 T PL21921687 T PL 21921687T PL 4180523 T3 PL4180523 T3 PL 4180523T3
Authority
PL
Poland
Prior art keywords
same
purine nucleotides
synthase variant
gmp synthase
producing purine
Prior art date
Application number
PL21921687.6T
Other languages
English (en)
Inventor
Nara Kwon
Ji Hyun Lee
Hyun-jung BAE
Dae Young Kim
Eunji Kim
Lan HUH
Hyeryun YOO
Bina KIM
Sung Kwang Son
Original Assignee
Cj Cheiljedang Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020210125841A external-priority patent/KR102419166B1/ko
Application filed by Cj Cheiljedang Corporation filed Critical Cj Cheiljedang Corporation
Publication of PL4180523T3 publication Critical patent/PL4180523T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/32Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y603/00Ligases forming carbon-nitrogen bonds (6.3)
    • C12Y603/05Carbon-nitrogen ligases with glutamine as amido-N-donor (6.3.5)
    • C12Y603/05002GMP synthase (glutamine-hydrolysing) (6.3.5.2), i.e. glutamine amidotransferase
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PL21921687.6T 2021-09-23 2021-12-17 Nowy wariant syntazy gmp hydrolizującej glutaminę i sposób wytwarzania nukleotydów purynowych z jego użyciem PL4180523T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020210125841A KR102419166B1 (ko) 2021-09-23 2021-09-23 신규한 글루타민 가수분해 gmp 합성효소 변이체 및 이를 이용한 퓨린 뉴클레오티드의 생산방법
PCT/KR2021/019303 WO2023048343A1 (ko) 2021-09-23 2021-12-17 신규한 글루타민 가수분해 gmp 합성효소 변이체 및 이를 이용한 퓨린 뉴클레오티드의 생산방법

Publications (1)

Publication Number Publication Date
PL4180523T3 true PL4180523T3 (pl) 2024-11-25

Family

ID=85685081

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21921687.6T PL4180523T3 (pl) 2021-09-23 2021-12-17 Nowy wariant syntazy gmp hydrolizującej glutaminę i sposób wytwarzania nukleotydów purynowych z jego użyciem

Country Status (12)

Country Link
US (1) US20240209342A1 (pl)
EP (1) EP4180523B1 (pl)
JP (2) JP7711078B2 (pl)
CN (1) CN116157524B (pl)
AU (1) AU2021420803B2 (pl)
CA (1) CA3170389A1 (pl)
ES (1) ES2992349T3 (pl)
MX (1) MX2022010627A (pl)
MY (1) MY209333A (pl)
PH (1) PH12022551919A1 (pl)
PL (1) PL4180523T3 (pl)
ZA (1) ZA202208933B (pl)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2383865A1 (en) * 1999-06-25 2001-01-04 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding metabolic pathway proteins
BR0014455A (pt) * 1999-10-01 2002-06-11 Basf Ag Sequência de dna, proteìna, uso de uma sequência de dna, métodos para encontrar substâncias, para identificar substâncias com ação herbicida e para eliminar crescimento de plantas indesejadas, sistema de teste, e, inibidor
JP5440489B2 (ja) * 2008-02-25 2014-03-12 味の素株式会社 5’−グアニル酸の製造法
JP5636648B2 (ja) * 2009-08-10 2014-12-10 味の素株式会社 5’−グアニル酸の製造法
KR101210704B1 (ko) 2010-03-19 2012-12-10 씨제이제일제당 (주) 5'-크산틸산 및 5'-구아닐산 생산능이 향상된 미생물 및 이를 이용한 5'-크산틸산 또는 5'-구아닐산의 생산방법
CN112574934B (zh) * 2020-10-12 2022-05-06 廊坊梅花生物技术开发有限公司 高产鸟苷的工程菌及其构建方法与应用

Also Published As

Publication number Publication date
EP4180523A4 (en) 2023-09-06
JP2023545878A (ja) 2023-11-01
AU2021420803B2 (en) 2024-06-13
PH12022551919A1 (en) 2024-01-08
CA3170389A1 (en) 2023-03-23
MX2022010627A (es) 2023-05-03
MY209333A (en) 2025-07-03
AU2021420803A1 (en) 2023-04-06
JP7711078B2 (ja) 2025-07-22
JP2024161506A (ja) 2024-11-19
EP4180523B1 (en) 2024-08-21
US20240209342A1 (en) 2024-06-27
ES2992349T3 (es) 2024-12-11
EP4180523A1 (en) 2023-05-17
ZA202208933B (en) 2023-12-20
CN116157524A (zh) 2023-05-23
CN116157524B (zh) 2023-10-20

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