[go: up one dir, main page]

PL3984590T3 - Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu - Google Patents

Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu

Info

Publication number
PL3984590T3
PL3984590T3 PL21205743.4T PL21205743T PL3984590T3 PL 3984590 T3 PL3984590 T3 PL 3984590T3 PL 21205743 T PL21205743 T PL 21205743T PL 3984590 T3 PL3984590 T3 PL 3984590T3
Authority
PL
Poland
Prior art keywords
ttfields
brain
high uniformity
uniformity throughout
tumor treating
Prior art date
Application number
PL21205743.4T
Other languages
English (en)
Inventor
Zeev Bomzon
Ariel NAEH
Ofir YESHARIM
Original Assignee
Novocure Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novocure Gmbh filed Critical Novocure Gmbh
Publication of PL3984590T3 publication Critical patent/PL3984590T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0456Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0476Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0492Patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/08Arrangements or circuits for monitoring, protecting, controlling or indicating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002Cancer treatment, e.g. tumour
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/3603Control systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Databases & Information Systems (AREA)
  • Urology & Nephrology (AREA)
  • General Business, Economics & Management (AREA)
  • Pathology (AREA)
  • Business, Economics & Management (AREA)
  • Data Mining & Analysis (AREA)
  • Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Social Psychology (AREA)
  • Electrotherapy Devices (AREA)
PL21205743.4T 2018-10-15 2019-10-11 Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu PL3984590T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862745689P 2018-10-15 2018-10-15

Publications (1)

Publication Number Publication Date
PL3984590T3 true PL3984590T3 (pl) 2023-05-02

Family

ID=68426548

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21205743.4T PL3984590T3 (pl) 2018-10-15 2019-10-11 Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu

Country Status (7)

Country Link
US (4) US11154707B2 (pl)
EP (4) EP3984590B1 (pl)
JP (2) JP7284886B2 (pl)
CN (3) CN112930209B (pl)
HU (1) HUE061361T2 (pl)
PL (1) PL3984590T3 (pl)
WO (1) WO2020079554A1 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10441776B2 (en) 2016-06-30 2019-10-15 Novocure Gmbh Arrays for longitudinal delivery of TTFields to a body
US11986647B2 (en) 2018-09-07 2024-05-21 Novocure Gmbh Treating autoinflammatory and mitochondrial diseases using an alternating electric field
HUE061361T2 (hu) 2018-10-15 2023-06-28 Novocure Gmbh Az egész agyban nagy egyenletességû tumorkezelõ mezõk (TT-mezõk) generálása
EP3870271A1 (en) 2018-10-25 2021-09-01 Zeev Bomzon Delivering alternating electric fields (e.g., ttfields) to a subject's spinal anatomy
WO2021111186A1 (en) 2019-12-02 2021-06-10 Novocure Gmbh Methods and apparatuses for optimizing transducer array placement
MX2022006135A (es) 2019-12-31 2022-06-17 Novocure Gmbh Generador de ondas sinusoidales de alta eficiencia, alto voltaje, que evita los picos durante los ajustes de amplitud y la conmutacion de canales.
WO2021137094A1 (en) 2019-12-31 2021-07-08 Novocure Gmbh Arrays for delivering tumor treating fields (ttfields) with individually accessible electrode elements and temperature sensors
EP4075442A1 (en) 2019-12-31 2022-10-19 Novocure GmbH Methods, systems, and apparatuses for fast approximation of electric field distribution
EP4105890A1 (en) 2019-12-31 2022-12-21 Novocure GmbH Methods, systems, and apparatuses for image segmentation
US20210299440A1 (en) 2020-03-30 2021-09-30 Novocure Gmbh Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases
JP2023522817A (ja) 2020-04-24 2023-06-01 ノボキュア ゲーエムベーハー 血液脳関門の透過性を増加させるための交流電界の使用
US11818943B2 (en) 2020-06-25 2023-11-14 Novocure Gmbh Fabricating organic light emitting diodes (OLEDs) using tubulin
US12114991B2 (en) 2020-09-25 2024-10-15 Novocure Gmbh Varying the metallization area on individual electrode elements in a tumor treating fields (TTFields) system to maximize current without overheating
US12194295B2 (en) 2020-09-30 2025-01-14 Novocure Gmbh Method and apparatus for delivering tumor treating fields to a torso, and method for determining locations for transducers to deliver tumor treating fields
TWI830958B (zh) * 2020-10-16 2024-02-01 瑞士商諾沃庫勒有限責任公司 用於判定傳感器陣列在個體之身體上之最佳位置以及規劃電極元件集合在個體之身體上之定位的方法
US11869151B2 (en) * 2021-01-26 2024-01-09 Beth Israel Deaconess Medical Center Systems and methods for finite element analysis of tumor treating fields
WO2022175803A1 (en) * 2021-02-17 2022-08-25 Novocure Gmbh Arrays for delivering tumor treating fields (ttfields) with sets of electrode elements having individually adjustable active areas
EP4304704A1 (en) 2021-03-12 2024-01-17 Novocure GmbH Methods of treating disease by skewing macrophage phenotype with alternating electric fields
EP4596025A1 (en) 2021-03-31 2025-08-06 Novocure Gmbh Impedance tomography using electrodes of a tumor treating fields (ttfields) system
EP4363047B1 (en) * 2021-06-30 2025-03-19 Novocure GmbH Nonconductive field guide for resection cavity, and systems of using same
EP4408516A1 (en) * 2021-09-30 2024-08-07 Novocure GmbH Reducing electrosensation whilst treating a subject using alternating electric fields
WO2023111863A1 (en) * 2021-12-14 2023-06-22 Novocure Gmbh Transducer array with shape that contours to a subject's body and method of determining shape and placement of transducer arrays
US12377280B2 (en) 2021-12-30 2025-08-05 Novocure Gmbh Selecting values of parameters for treatment using tumor treating fields (TTFields)
CA3255016A1 (en) 2022-03-30 2023-10-05 Novocure Gmbh REDUCING ELECTROSENSITIVITY WHILE TREATING A SUBJECT WITH ALTERNATING ELECTRIC FIELDS BY MATCHING TRANSDUCER NETWORKS TOGETHER
IL314390A (en) 2022-03-30 2024-09-01 Novocure Gmbh Using interleaved cooling periods to increase the peak intensity of tumor treating fields
US12268863B2 (en) 2023-02-06 2025-04-08 Novocure Gmbh Shiftable transducer array with anisotropic material layer
CN119421730B (zh) * 2023-02-06 2025-09-23 诺沃库勒有限责任公司 具有各向异性材料层的可移位换能器阵列
SE2350150A1 (en) * 2023-02-15 2024-08-16 Force Oncology Ab Tumor treating fields (ttfields) equipment configurations for improved ease-of-use

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6081744A (en) * 1993-05-28 2000-06-27 Loos; Hendricus G. Electric fringe field generator for manipulating nervous systems
US6366813B1 (en) * 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US8447395B2 (en) 2000-02-17 2013-05-21 Novocure Ltd Treating bacteria with electric fields
US7599746B2 (en) 2000-02-17 2009-10-06 Standen Ltd Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases
WO2001060994A1 (en) 2000-02-17 2001-08-23 Palti Yoram Prof Method and apparatus for destroying dividing cells
US7089054B2 (en) 2002-10-02 2006-08-08 Standen Ltd. Apparatus and method for treating a tumor or the like
US7136699B2 (en) 2002-10-02 2006-11-14 Standen, Ltd. Apparatus for destroying dividing cells
US7146210B2 (en) 2000-02-17 2006-12-05 Standen Ltd. Apparatus and method for optimizing tumor treatment efficiency by electric fields
US7805201B2 (en) 2000-02-17 2010-09-28 Standen Ltd. Treating a tumor or the like with an electric field
US8175698B2 (en) 2000-02-17 2012-05-08 Novocure Ltd. Treating bacteria with electric fields
US6868289B2 (en) 2002-10-02 2005-03-15 Standen Ltd. Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor
US7016725B2 (en) 2001-11-06 2006-03-21 Standen Ltd. Method and apparatus for destroying dividing cells
CA2426810A1 (en) * 2000-10-26 2002-06-13 Medtronic, Inc. Method and apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac comditions
PT2345451T (pt) 2004-12-07 2018-04-19 Novocure Ltd Eléctrodos para aplicar um campo eléctrico in-vivo ao longo de um extenso período de tempo
EP3666328B1 (en) 2004-12-27 2022-04-06 Novocure GmbH Treating a tumor or the like with electric fields at different orientations
WO2007039799A2 (en) 2005-10-03 2007-04-12 Novocure Ltd. Optimizing characteristics of an electric field to increase the field's effect on proliferating cells
US10537728B2 (en) 2005-11-10 2020-01-21 ElectroCore, LLC Vagal nerve stimulation to avert or treat stroke or transient ischemic attack
US8019414B2 (en) 2006-04-05 2011-09-13 Novocure Ltd. Treating cancer using electromagnetic fields in combination with other treatment regimens
US7949403B2 (en) * 2007-02-27 2011-05-24 Accelerated Care Plus Corp. Electrical stimulation device and method for the treatment of neurological disorders
EP2167194B1 (en) 2007-03-06 2017-04-19 Novocure Ltd. Treating cancer using electromagnetic fields in combination with photodynamic therapy
CA2696352C (en) 2007-08-14 2017-03-21 Novocure Limited Treating parasites with electric fields
US8715203B2 (en) * 2007-09-17 2014-05-06 Novocure Limited Composite electrode
CA2765891A1 (en) * 2008-06-18 2009-12-23 Accelerated Care Plus Corp. Electrical stimulation method for reduction of joint compression
US8968173B2 (en) * 2008-07-16 2015-03-03 Frank Sivo Methods to arrest cancer cell growth and proliferation using electromagnetic energy delivered via electromagnetic coil systems
US20170164878A1 (en) * 2012-06-14 2017-06-15 Medibotics Llc Wearable Technology for Non-Invasive Glucose Monitoring
US9180302B2 (en) * 2012-08-31 2015-11-10 Greatbatch Ltd. Touch screen finger position indicator for a spinal cord stimulation programming device
WO2014113813A1 (en) * 2013-01-21 2014-07-24 Cala Health, Inc. Devices and methods for controlling tremor
EP2983629B1 (en) * 2013-04-10 2022-06-08 Zoll Circulation, Inc. Detecting and responding to preshivering
US10779875B2 (en) 2013-05-06 2020-09-22 Novocure Gmbh Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment
US9655669B2 (en) 2013-05-06 2017-05-23 Novocure Limited Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment
US20140371566A1 (en) * 2013-06-14 2014-12-18 Cardiothrive, Inc. Conforming patient contact interface and method for using same
US10293161B2 (en) * 2013-06-29 2019-05-21 Thync Global, Inc. Apparatuses and methods for transdermal electrical stimulation of nerves to modify or induce a cognitive state
US20150094557A1 (en) 2013-09-30 2015-04-02 Mediatek Inc. Patches for bio-electrical signal processing
US9498635B2 (en) * 2013-10-16 2016-11-22 Syntilla Medical LLC Implantable head located radiofrequency coupled neurostimulation system for head pain
US9358396B2 (en) * 2013-11-01 2016-06-07 Boston Scientific Neuromodulation Corporation Systems and methods for delivering sub-threshold therapy to a patient at a physiological midline
US20150224318A1 (en) * 2014-02-12 2015-08-13 Pacesetter, Inc. Methods and systems for neurostimulation using paddle lead
EP3145584B1 (en) * 2014-05-23 2022-02-16 electroCore, Inc. Systems for vagal nerve stimulation
US9393401B2 (en) * 2014-05-25 2016-07-19 Thync Global, Inc. Wearable transdermal neurostimulator having cantilevered attachment
CN107949351A (zh) * 2015-03-30 2018-04-20 伊诺佩斯生物医药有限公司 用于血管内装置的天线
US9910453B2 (en) 2015-09-25 2018-03-06 Novocure Limited High voltage, high efficiency sine wave generator with pre-set frequency and adjustable amplitude
US10188851B2 (en) 2015-10-28 2019-01-29 Novocure Limited TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements
US9956405B2 (en) * 2015-12-18 2018-05-01 Thyne Global, Inc. Transdermal electrical stimulation at the neck to induce neuromodulation
US10821283B2 (en) 2016-04-04 2020-11-03 Novocure Gmbh Reducing motility of cancer cells using tumor treating fields (TTFields)
US10646708B2 (en) * 2016-05-20 2020-05-12 Thync Global, Inc. Transdermal electrical stimulation at the neck
US10441776B2 (en) * 2016-06-30 2019-10-15 Novocure Gmbh Arrays for longitudinal delivery of TTFields to a body
US20180008708A1 (en) 2016-07-10 2018-01-11 Novocure Limited Synchronizing Tumor Cells to the G2/M Phase Using TTFields Combined with Taxane or Other Anti-Microtubule Agents
DK3500334T3 (da) 2016-08-18 2023-10-09 Novocure Gmbh Temperaturmåling i arrays til levering af ttfields
US11446487B2 (en) * 2016-09-23 2022-09-20 Beth Israel Deaconess Medical Center, Inc. System and methods for cancer treatment using alternating electric fields
ES2916252T3 (es) * 2016-12-13 2022-06-29 Novocure Gmbh Tratamiento de pacientes con campos TT con las posiciones de los electrodos optimizadas utilizando plantillas deformables
US11573221B2 (en) 2017-01-19 2023-02-07 Novocure Gmbh System for viewing cell cultures under a microscope whilst applying TTFields
PL421532A1 (pl) * 2017-05-08 2018-11-19 Michalczyk Marta System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii
US20180333574A1 (en) * 2017-05-22 2018-11-22 Sumon K. PAL Systems and methods for applying electrical energy to treat psoriasis
JP2021503360A (ja) 2017-11-17 2021-02-12 アッヴィ・インコーポレイテッド 膠芽腫の処置方法
US10953209B2 (en) 2018-03-28 2021-03-23 Board Of Regents Of The University Of Texas System Treating tumors using TTFields combined with a PARP inhibitor
EP3773726B1 (en) 2018-04-09 2024-06-05 Novocure GmbH Treating tumors with ttfields and an aurora kinase inhibitor
CN112424626B (zh) 2018-04-10 2025-07-08 诺沃库勒有限责任公司 优化多个电极位置并创建3d模型的方法
CN116236688A (zh) 2018-07-03 2023-06-09 埃德温·阊 使用交变电场提高细胞膜通透性
MX2020013427A (es) 2018-07-10 2021-05-27 Novocure Gmbh Inhibicion de infecciones virales usando campos electricos alternos.
US11179322B2 (en) 2018-07-10 2021-11-23 Novocure Gmbh Methods and compositions for treating tumors with TTFields and sorafenib
EP3823715A1 (en) 2018-07-18 2021-05-26 Novocure GmbH Using power loss density and related measures to quantify the dose of tumor treating fields (ttfields)
CA3242209A1 (en) 2018-08-23 2020-02-27 Novocure Gmbh Using alternating electric fields to increase permeability of the blood brain barrier
US11160977B2 (en) * 2018-09-04 2021-11-02 Novocure Gmbh Delivering tumor treating fields (TTFields) to the infratentorial brain
US11020585B2 (en) 2018-09-07 2021-06-01 Novocure Gmbh Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells
US11986647B2 (en) 2018-09-07 2024-05-21 Novocure Gmbh Treating autoinflammatory and mitochondrial diseases using an alternating electric field
US20200108031A1 (en) 2018-10-05 2020-04-09 Novocure Gmbh Treating Tumors Using TTFields Combined with ABT-751
HUE061361T2 (hu) * 2018-10-15 2023-06-28 Novocure Gmbh Az egész agyban nagy egyenletességû tumorkezelõ mezõk (TT-mezõk) generálása
EP3870188B1 (en) 2018-10-23 2024-06-19 The Board of Trustees of the Leland Stanford Junior University Prevention and treatment of teratoma formation in stem cell-based thereapies using alternating electric fields
EP3870271A1 (en) 2018-10-25 2021-09-01 Zeev Bomzon Delivering alternating electric fields (e.g., ttfields) to a subject's spinal anatomy
US20200146586A1 (en) 2018-11-14 2020-05-14 Novocure Gmbh Creating Accurate Computational Head Models of Patients Using Datasets Combining MRI and CT Images
CN113015553B (zh) 2018-11-19 2025-01-14 诺沃库勒有限责任公司 用于递送具有选择性可寻址子元件的肿瘤治疗场(TTField)的阵列
JP7246486B2 (ja) 2019-01-08 2023-03-27 ノボキュア ゲーエムベーハー 腫瘍治療電場(ttfields)を使用した治療を計画するための異なるタイプの組織への画像のセグメンテーションの品質評価
US11911610B2 (en) 2019-03-29 2024-02-27 Novocure Gmbh Methods for restoring sensitivity to TTFields in TTFields-resistant cancer cells with PTGER3 inhibitors
ES2940749T3 (es) 2019-04-17 2023-05-11 Novocure Gmbh Carga de datos desde un sistema aislado sin comprometer el aislamiento
USD934892S1 (en) 2019-05-03 2021-11-02 Novocure Gmbh Display screen or portion thereof with a graphical user interface
US11654279B2 (en) 2019-07-31 2023-05-23 Novocure Gmbh Applying tumor treating fields (TTFields) via electrodes embedded into skull implants
WO2021024170A1 (en) 2019-08-05 2021-02-11 Voloshin Sela Tali Increasing cancer cells' sensitivity to tumor treating fields (ttfields) by inhibiting il11 activity
CN114364433A (zh) 2019-08-30 2022-04-15 诺沃库勒有限责任公司 向颈部输送肿瘤治疗场(TTFields)
EP4028052A1 (en) 2019-09-10 2022-07-20 Novocure GmbH A method of reducing viability of cancer cells by applying alternating electric fields and administering checkpoint inhibitors to the cancer cells
US20210199640A1 (en) 2019-12-26 2021-07-01 The Board of Trustees of the Leland Stanford Junior Unviersity Methods of Normalizing Aberrant Glycolytic Metabolism in Cancer Cells
MX2022006135A (es) 2019-12-31 2022-06-17 Novocure Gmbh Generador de ondas sinusoidales de alta eficiencia, alto voltaje, que evita los picos durante los ajustes de amplitud y la conmutacion de canales.
WO2021137094A1 (en) 2019-12-31 2021-07-08 Novocure Gmbh Arrays for delivering tumor treating fields (ttfields) with individually accessible electrode elements and temperature sensors
US20210299440A1 (en) 2020-03-30 2021-09-30 Novocure Gmbh Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases
JP2023522817A (ja) 2020-04-24 2023-06-01 ノボキュア ゲーエムベーハー 血液脳関門の透過性を増加させるための交流電界の使用

Also Published As

Publication number Publication date
US12208275B2 (en) 2025-01-28
US20240082592A1 (en) 2024-03-14
EP4137195C0 (en) 2024-12-11
EP4137195B1 (en) 2024-12-11
US11154707B2 (en) 2021-10-26
EP3840823A1 (en) 2021-06-30
US11241577B2 (en) 2022-02-08
EP3878505A1 (en) 2021-09-15
US20200114141A1 (en) 2020-04-16
JP2022512690A (ja) 2022-02-07
EP3840823C0 (en) 2023-07-12
HUE061361T2 (hu) 2023-06-28
EP3840823B1 (en) 2023-07-12
EP3984590A1 (en) 2022-04-20
CN112930209A (zh) 2021-06-08
JP2023083291A (ja) 2023-06-15
EP3984590B1 (en) 2022-12-07
US11865355B2 (en) 2024-01-09
EP3878505B1 (en) 2023-05-24
US20200114142A1 (en) 2020-04-16
EP4137195A1 (en) 2023-02-22
JP7284886B2 (ja) 2023-06-01
WO2020079554A1 (en) 2020-04-23
CN118925057A (zh) 2024-11-12
CN112930209B (zh) 2024-10-15
US20220118249A1 (en) 2022-04-21
CN118925056A (zh) 2024-11-12
JP7536934B2 (ja) 2024-08-20

Similar Documents

Publication Publication Date Title
PL3984590T3 (pl) Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu
IL280844A (en) Transducer arrays with improved flexibility to provide tumor treating fields
IL280843A (en) Arrays for administration of fields treat the tumor with sub-elements administered selectively
IL291844B1 (en) smc combined therapy for cancer treatment
ZA201905902B (en) 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer
GB201719076D0 (en) Particles for the treatment of cancer in combination with radiotherapy
PL3439733T3 (pl) Zmniejszanie ruchliwości komórek nowotworowych z użyciem leczących nowotwory pól (ttfields)
ZA202004913B (en) Improved microbes and methods for producing the same
EP3832003A4 (en) GARMENT TREATMENT APPARATUS
EP4061477C0 (en) IMPLANTABLE NETWORKS TO PROVIDE TUMOR TREATMENT FIELDS
ZA202203776B (en) Methods of treating epilepsy using the same
PH12018501455A1 (en) Therapeutic compostions and methods for treating hepatitis b
IL261160B (en) Methods of treating acute myeloid leukemia
GB201811630D0 (en) Radiotherapy apparatus
IL277739A (en) Radiotherapy process and system
GB201707503D0 (en) New Therapy 3
GB201707501D0 (en) New therapy 2
SI3423440T1 (sl) 5-metil-6-fenil-4,5-dihidro-2H-piridazin-3-ON derivat za zdravljenje možganskih tumorjev
EP3674398A4 (en) ECHOVIRUS FOR TUMOR TREATMENT
ZA202101493B (en) Hair treatment process
KR102167683B9 (ko) 고주파 심부열 발생장치
IL269681A (en) New methods for treating multiple sclerosis
GB201819920D0 (en) Cancer treatment
HK40115898A (zh) 使用组合疗法治疗脑肿瘤的方法
GB201907204D0 (en) Cancer treatment 3