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PL382055A1 - Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu - Google Patents

Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu

Info

Publication number
PL382055A1
PL382055A1 PL382055A PL38205507A PL382055A1 PL 382055 A1 PL382055 A1 PL 382055A1 PL 382055 A PL382055 A PL 382055A PL 38205507 A PL38205507 A PL 38205507A PL 382055 A1 PL382055 A1 PL 382055A1
Authority
PL
Poland
Prior art keywords
clopidogrel
production method
crystalline form
hydrogen sulphate
sulphate
Prior art date
Application number
PL382055A
Other languages
English (en)
Inventor
Tomasz Koźluk
Robert Woźniak
Original Assignee
Koźluk Tomasz Nobilus Ent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koźluk Tomasz Nobilus Ent filed Critical Koźluk Tomasz Nobilus Ent
Priority to PL382055A priority Critical patent/PL382055A1/pl
Priority to EP08741764A priority patent/EP2139902A1/en
Priority to US12/531,888 priority patent/US20100216999A1/en
Priority to PCT/PL2008/000023 priority patent/WO2008118030A1/en
Publication of PL382055A1 publication Critical patent/PL382055A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL382055A 2007-03-23 2007-03-23 Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu PL382055A1 (pl)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PL382055A PL382055A1 (pl) 2007-03-23 2007-03-23 Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu
EP08741764A EP2139902A1 (en) 2007-03-23 2008-03-19 Process for preparation of pure polymorphic form 1 of clopidogrel hydrogensulfate
US12/531,888 US20100216999A1 (en) 2007-03-23 2008-03-19 Process for preparation of pure polymorphic form 1 of clopidogrel hydrogensulfate
PCT/PL2008/000023 WO2008118030A1 (en) 2007-03-23 2008-03-19 Process for preparation of pure polymorphic form 1 of clopidogrel hydrogensulfate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL382055A PL382055A1 (pl) 2007-03-23 2007-03-23 Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu

Publications (1)

Publication Number Publication Date
PL382055A1 true PL382055A1 (pl) 2008-09-29

Family

ID=39628754

Family Applications (1)

Application Number Title Priority Date Filing Date
PL382055A PL382055A1 (pl) 2007-03-23 2007-03-23 Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu

Country Status (4)

Country Link
US (1) US20100216999A1 (pl)
EP (1) EP2139902A1 (pl)
PL (1) PL382055A1 (pl)
WO (1) WO2008118030A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010046852A1 (en) * 2008-10-20 2010-04-29 Ranbaxy Laboratories Limited Process for the preparation of clopidogrel hydrogen sulphate form 1
WO2011042804A2 (en) * 2009-10-08 2011-04-14 Jubliant Life Sciences Limited An improved process for the preparation of clopidogrel hydrogen sulfate form i
WO2011051976A2 (en) * 2009-10-30 2011-05-05 Matrix Laboratories Ltd An improved process for the preparation of clopidogrel bisulfate form i
EP2491044A4 (en) * 2009-11-09 2013-04-24 Pharmazell Gmbh IMPROVED METHOD FOR THE PREPARATION OF CLOPIODOGREL BISULFATE IN THE CRYSTAL FORM 1
WO2011125069A1 (en) * 2010-03-22 2011-10-13 Rpg Life Sciences Limited A process for preparation of crystalline form i of clopidogrel bisulfate
CN102558194A (zh) * 2010-12-11 2012-07-11 山东方明药业股份有限公司 一种硫酸氢氯吡格雷i型的制备方法
WO2020013305A1 (ja) * 2018-07-12 2020-01-16 有機合成薬品工業株式会社 クロピドグレル硫酸塩のｉ型結晶の製造方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) * 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
HU225503B1 (en) * 1997-05-13 2007-01-29 Sanofi Aventis Novel 2-(2-halophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides and process for producing them
FR2779726B1 (fr) * 1998-06-15 2001-05-18 Sanofi Sa Forme polymorphe de l'hydrogenosulfate de clopidogrel
US7074928B2 (en) * 2002-01-11 2006-07-11 Teva Pharmaceutical Industries, Ltd. Polymorphs of clopidogrel hydrogensulfate
WO2004048385A2 (en) * 2002-11-28 2004-06-10 Instytut Farmaceutyczny A process for the preparation of crystalline form 1 or clopidogrel hydrogen sulfate
WO2005012300A1 (en) * 2003-08-04 2005-02-10 Wockhardt Limited A novel process for the manufacture of (+)-(s)-clopidogrel bisulfate form-i
DE10337773A1 (de) * 2003-08-13 2005-03-24 Krka Tovarna Zdravil, D.D. Kristallisation von festen Formen von Clopidogrel-Additionssalzen
US7629465B2 (en) * 2004-03-05 2009-12-08 Ipca Laboratories Ltd. Industrial process for preparation of Clopidogrel hydrogen sulphate
EP1740593B1 (en) * 2004-04-19 2016-04-06 KRKA, tovarna zdravil, d.d., Novo mesto Processes for the preparation of clopidogrel hydrogen sulfate polymorphic form i
CA2567806C (en) * 2005-02-15 2011-04-26 Usv Limited Rapid resolution process of clopidogrel base and a process for preparation of clopidogrel bisulfate polymorph - form i
EP1693375A1 (en) * 2005-02-21 2006-08-23 KRKA, tovarna zdravil, d.d., Novo mesto Process for preparing clopidrogel hydrogen sulfate of form I
US7772398B2 (en) * 2005-03-11 2010-08-10 Dr. Reddy's Laboratories, Inc. Process for making crystalline form I of clopidogrel hydrogen sulphate
MX2008013724A (es) * 2006-04-27 2009-06-19 Ind Swift Lab Ltd Proceso para la preparacion de formas polimorficas de hidrogeno sulfato clopidrogel.
WO2008004249A2 (en) * 2006-07-04 2008-01-10 Msn Laboratories Limited An improved process for the preparation of clopidogrel and its pharmaceutically acceptable salts
TW200825093A (en) * 2006-08-03 2008-06-16 Teva Pharma Process for preparing clopidogrel bisulphate

Also Published As

Publication number Publication date
WO2008118030A1 (en) 2008-10-02
EP2139902A1 (en) 2010-01-06
US20100216999A1 (en) 2010-08-26

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