PL3813816T3 - Zastosowanie kwasu (s)-3-amino-4-(difluorometylenylo)cyklopentano-1-eno-1-karboksylowego i związków pokrewnych, kwasu (1s,3s)-3-amino-4-(difluorometylideno)cyklopentano-1-karboksylowego w leczeniu zespołu łamliwego chromosomu x lub zespołu drżenia/ataksji związanego z zespołem łamliwego chromosomu x - Google Patents
Zastosowanie kwasu (s)-3-amino-4-(difluorometylenylo)cyklopentano-1-eno-1-karboksylowego i związków pokrewnych, kwasu (1s,3s)-3-amino-4-(difluorometylideno)cyklopentano-1-karboksylowego w leczeniu zespołu łamliwego chromosomu x lub zespołu drżenia/ataksji związanego z zespołem łamliwego chromosomu xInfo
- Publication number
- PL3813816T3 PL3813816T3 PL19815892.5T PL19815892T PL3813816T3 PL 3813816 T3 PL3813816 T3 PL 3813816T3 PL 19815892 T PL19815892 T PL 19815892T PL 3813816 T3 PL3813816 T3 PL 3813816T3
- Authority
- PL
- Poland
- Prior art keywords
- fragile
- amino
- carboxylic acid
- syndrome
- difluoromethylenyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862681913P | 2018-06-07 | 2018-06-07 | |
| PCT/US2019/035934 WO2019236938A1 (en) | 2018-06-07 | 2019-06-07 | Use of (s)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid and related compounds, (1s,3s)-3-amino-4-(difluoromethylidene) cyclopentane-1-carboxylic acid and vigabatrin in the treatment of developmental disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3813816T3 true PL3813816T3 (pl) | 2023-07-31 |
Family
ID=68765508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19815892.5T PL3813816T3 (pl) | 2018-06-07 | 2019-06-07 | Zastosowanie kwasu (s)-3-amino-4-(difluorometylenylo)cyklopentano-1-eno-1-karboksylowego i związków pokrewnych, kwasu (1s,3s)-3-amino-4-(difluorometylideno)cyklopentano-1-karboksylowego w leczeniu zespołu łamliwego chromosomu x lub zespołu drżenia/ataksji związanego z zespołem łamliwego chromosomu x |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10813899B2 (pl) |
| EP (1) | EP3813816B1 (pl) |
| JP (1) | JP7387179B2 (pl) |
| KR (1) | KR102744830B1 (pl) |
| CN (1) | CN112770739B (pl) |
| AU (1) | AU2019280980B2 (pl) |
| CA (1) | CA3102786A1 (pl) |
| ES (1) | ES2948263T3 (pl) |
| IL (2) | IL304270B2 (pl) |
| MX (2) | MX2020013290A (pl) |
| PL (1) | PL3813816T3 (pl) |
| WO (1) | WO2019236938A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3813816T3 (pl) | 2018-06-07 | 2023-07-31 | Ovid Therapeutics Inc. | Zastosowanie kwasu (s)-3-amino-4-(difluorometylenylo)cyklopentano-1-eno-1-karboksylowego i związków pokrewnych, kwasu (1s,3s)-3-amino-4-(difluorometylideno)cyklopentano-1-karboksylowego w leczeniu zespołu łamliwego chromosomu x lub zespołu drżenia/ataksji związanego z zespołem łamliwego chromosomu x |
| US20240285565A1 (en) * | 2023-02-17 | 2024-08-29 | Ovid Therapeutics Inc. | Use of (s)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid in the treatment of diabetes and pre-diabetes |
| US20240285564A1 (en) * | 2023-02-17 | 2024-08-29 | Ovid Therapeutics Inc. | Use of (s)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid for gastrointestinal tract disorders and as an immunomodulatory agent |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6794413B1 (en) | 2002-07-19 | 2004-09-21 | Northwestern University | Compounds and related methods for inhibition of γ-aminobutyric acid aminotransferase |
| WO2005120496A2 (en) | 2004-05-24 | 2005-12-22 | Regents Of The University Of California | TREATING LEARNING DEFICITS WITH INHIBITORS OF HMG CoA REDUCTASE |
| WO2009033818A2 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
| CA2790820A1 (en) | 2010-02-25 | 2011-09-01 | Northwestern University | Use (1s,3s)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid as a gaba aminotransferse inhibitor |
| WO2012042314A1 (en) | 2010-10-02 | 2012-04-05 | Link Research & Grants Corporation | Treatment of tinnitus and related auditory dysfunctions |
| WO2013006857A1 (en) | 2011-07-07 | 2013-01-10 | The Children's Hospital Of Philadelphia | Genetic alterations associated with autism and the autistic phenotype and methods of use thereof for the diagnosis and treatment of autism |
| WO2013112363A1 (en) | 2012-01-27 | 2013-08-01 | Catalyst Pharmaceutical Partners | Method of treating tourette's disorder with gaba-aminotransferase inactivators |
| TW201606304A (zh) * | 2013-09-09 | 2016-02-16 | 亞克柏拉有限公司 | 測定治療反應之方法 |
| US20150224164A1 (en) | 2013-11-26 | 2015-08-13 | Neuren Pharmaceuticals Limited | Treatment of autism spectrum disorders using glycyl-l-2-methylprolyl-l-glumatic acid |
| US9603820B2 (en) | 2014-11-07 | 2017-03-28 | Northwestern University | Ornithine aminotransferase inhibition with GABA analogues for treatment of hepatocellular carcinoma |
| US20170348232A1 (en) * | 2016-06-07 | 2017-12-07 | Ovid Therapeutics Inc. | Formulations of gaboxadol for treatment of angelman syndrome, fragile x syndrome and fragile x-associated tremor/ataxia syndrome |
| PL3341355T3 (pl) | 2015-10-09 | 2021-03-08 | Northwestern University | Kwas (S)-3-amino-4-(difluorometylenylo)cyklopent-1-eno-1-karboksylowy i związki pokrewne jako dezaktywatory aminotransferazy GABA do leczenia padaczki, uzależnienia oraz raka wątrobowokomórkowego |
| US10632088B2 (en) | 2016-10-10 | 2020-04-28 | Northwestern University | Inactivators of Toxoplasma gondii ornithine aminotransferase for treating toxoplasmosis and malaria |
| EP3579826A4 (en) * | 2017-02-08 | 2020-11-18 | Ovid Therapeutics Inc | METHODS OF TREATMENT OF EPILEPTIC DISORDERS AND PRADER-WILLI SYNDROME |
| BR112020009255A2 (pt) * | 2017-11-14 | 2020-10-20 | Sk Biopharmaceuticals Co., Ltd. | medicamentos para o alívio ou tratamento de distúrbio de desenvolvimento, para o alívio ou tratamento de síndrome do x frágil, para o alívio ou tratamento de síndrome de angelman e para o alívio ou tratamento de síndrome de rett |
| IL278932B2 (en) | 2018-05-25 | 2024-03-01 | Univ Northwestern | PROCESS FOR THE SYNTHESIS OF (S)-3-AMINO-4-(DIFLUOROMETHYLENYL)CYCLOPENT-l-ENE-l-CARBOXYLIC ACID |
| PL3813816T3 (pl) | 2018-06-07 | 2023-07-31 | Ovid Therapeutics Inc. | Zastosowanie kwasu (s)-3-amino-4-(difluorometylenylo)cyklopentano-1-eno-1-karboksylowego i związków pokrewnych, kwasu (1s,3s)-3-amino-4-(difluorometylideno)cyklopentano-1-karboksylowego w leczeniu zespołu łamliwego chromosomu x lub zespołu drżenia/ataksji związanego z zespołem łamliwego chromosomu x |
-
2019
- 2019-06-07 PL PL19815892.5T patent/PL3813816T3/pl unknown
- 2019-06-07 MX MX2020013290A patent/MX2020013290A/es unknown
- 2019-06-07 IL IL304270A patent/IL304270B2/en unknown
- 2019-06-07 IL IL279220A patent/IL279220B2/en unknown
- 2019-06-07 ES ES19815892T patent/ES2948263T3/es active Active
- 2019-06-07 KR KR1020217000541A patent/KR102744830B1/ko active Active
- 2019-06-07 AU AU2019280980A patent/AU2019280980B2/en active Active
- 2019-06-07 JP JP2020567857A patent/JP7387179B2/ja active Active
- 2019-06-07 CA CA3102786A patent/CA3102786A1/en active Pending
- 2019-06-07 WO PCT/US2019/035934 patent/WO2019236938A1/en not_active Ceased
- 2019-06-07 EP EP19815892.5A patent/EP3813816B1/en active Active
- 2019-06-07 CN CN201980052607.5A patent/CN112770739B/zh active Active
- 2019-06-07 US US16/434,300 patent/US10813899B2/en active Active
-
2020
- 2020-10-16 US US17/072,511 patent/US11660277B2/en active Active
- 2020-12-07 MX MX2023006497A patent/MX2023006497A/es unknown
-
2023
- 2023-04-19 US US18/302,997 patent/US12285397B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US12285397B2 (en) | 2025-04-29 |
| AU2019280980A1 (en) | 2021-01-07 |
| CN112770739A (zh) | 2021-05-07 |
| IL304270B2 (en) | 2024-10-01 |
| IL279220A (en) | 2021-01-31 |
| EP3813816C0 (en) | 2023-06-07 |
| JP2021527053A (ja) | 2021-10-11 |
| IL304270B1 (en) | 2024-06-01 |
| US20210100763A1 (en) | 2021-04-08 |
| US10813899B2 (en) | 2020-10-27 |
| EP3813816A1 (en) | 2021-05-05 |
| ES2948263T3 (es) | 2023-09-07 |
| MX2023006497A (es) | 2023-06-21 |
| US20190374492A1 (en) | 2019-12-12 |
| CA3102786A1 (en) | 2019-12-12 |
| IL304270A (en) | 2023-09-01 |
| EP3813816A4 (en) | 2021-06-23 |
| CN112770739B (zh) | 2023-12-12 |
| KR102744830B1 (ko) | 2024-12-19 |
| US20230255914A1 (en) | 2023-08-17 |
| IL279220B1 (en) | 2023-08-01 |
| US11660277B2 (en) | 2023-05-30 |
| KR20210035802A (ko) | 2021-04-01 |
| WO2019236938A1 (en) | 2019-12-12 |
| AU2019280980B2 (en) | 2025-02-27 |
| JP7387179B2 (ja) | 2023-11-28 |
| EP3813816B1 (en) | 2023-06-07 |
| MX2020013290A (es) | 2021-04-29 |
| IL279220B2 (en) | 2023-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL289975A (en) | Use of cannabidiol in the treatment of Derva syndrome | |
| GB201915517D0 (en) | Use of cannabidiol preparations in the treatment of fragile X syndrome | |
| AU2018295515A1 (en) | Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes | |
| GB201915522D0 (en) | Use of cannabidiol preparations in the treatment of absence epilepsy | |
| IL268125A (en) | Pridopidine for the treatment of fragile x syndrome | |
| ZA201801300B (en) | Composition and medical device comprising acetylsalicylic acid for the treatment of human papilloma virus skin infections | |
| IL269555A (en) | Glatiramer depot systems for treating progressive forms of multiple sclerosis | |
| IL287704A (en) | Use of cannabidiol in the treatment of multiple sclerosis complex | |
| EP3280722B8 (en) | Antimicrobial peptides and their use for the treatment of topical infections | |
| PL3813816T3 (pl) | Zastosowanie kwasu (s)-3-amino-4-(difluorometylenylo)cyklopentano-1-eno-1-karboksylowego i związków pokrewnych, kwasu (1s,3s)-3-amino-4-(difluorometylideno)cyklopentano-1-karboksylowego w leczeniu zespołu łamliwego chromosomu x lub zespołu drżenia/ataksji związanego z zespołem łamliwego chromosomu x | |
| IL277599A (en) | Use of (1S, 3S)-3-amino-4-(difluoromethylidene)cyclopentane-1-carboxylic acid and (S)-3-amino-4-(difluoromethylenyl)cyclopentane-1-ene-1-carboxylic acid in the treatment of eye disorders | |
| IL288531A (en) | Broad-spectrum antibacterial pharmaceutical formulations comprising lyses and methods of using them | |
| ZA202104891B (en) | Liposomial eye drops solution and uses thereof for the treatment of dry eye syndrome | |
| IL285265A (en) | Triamtrin or nolatrexad for use in the treatment of phenylketonuria | |
| HUE051948T2 (hu) | Protokollok és eljárások sclerosis multiplex kezelésére ofatumumab alkalmazásával | |
| EP3611170A4 (en) | ANXIOLYTIC COMPOUNDS BY DEUTERATION AND MEDICAL APPLICATIONS | |
| IL277253A (en) | Formulations of cyclosporine and use in the treatment of obliterative bronchiolitis syndrome | |
| WO2017100600A3 (en) | Methods and systems for stiffening of tissue for improved processing | |
| WO2016072854A3 (en) | Pantothenamide analogues | |
| WO2019025803A3 (en) | ANTIMICROBIAL COMPOSITION | |
| HK40092172A (en) | Pharmaceutical use of an extended-release composition containing pirfenidone for the treatment and reversal of human steatohepatitis | |
| HK40045205A (en) | Use of (1s,3s)-3-amino-4-(difluoromethylidene) cyclopentane-1-carboxylic acid and (s)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid in the treatment of eye disorders | |
| HK40043299B (en) | Liposomial eye drops solution and uses thereof for the treatment of dry eye syndrome | |
| HK40074743A (en) | Methylthioninium for use in the treatment of synaptopathies | |
| HK40075457A (en) | Use of cannabidiol in the treatment of dravet syndrome |