PL385805A1 - Sposób wytwarzania imatinibu - Google Patents
Sposób wytwarzania imatinibuInfo
- Publication number
- PL385805A1 PL385805A1 PL385805A PL38580508A PL385805A1 PL 385805 A1 PL385805 A1 PL 385805A1 PL 385805 A PL385805 A PL 385805A PL 38580508 A PL38580508 A PL 38580508A PL 385805 A1 PL385805 A1 PL 385805A1
- Authority
- PL
- Poland
- Prior art keywords
- imatinib
- manufacturing
- imatinib manufacturing
- Prior art date
Links
- 239000005517 L01XE01 - Imatinib Substances 0.000 title 1
- KTUFNOKKBVMGRW-UHFFFAOYSA-N imatinib Chemical compound C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 KTUFNOKKBVMGRW-UHFFFAOYSA-N 0.000 title 1
- 229960002411 imatinib Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL385805A PL215042B1 (pl) | 2008-08-01 | 2008-08-01 | Sposób wytwarzania imatinibu |
| PCT/PL2009/000077 WO2010014022A1 (en) | 2008-08-01 | 2009-07-30 | A process for the preparation of imatinib |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL385805A PL215042B1 (pl) | 2008-08-01 | 2008-08-01 | Sposób wytwarzania imatinibu |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL385805A1 true PL385805A1 (pl) | 2010-02-15 |
| PL215042B1 PL215042B1 (pl) | 2013-10-31 |
Family
ID=41168537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL385805A PL215042B1 (pl) | 2008-08-01 | 2008-08-01 | Sposób wytwarzania imatinibu |
Country Status (2)
| Country | Link |
|---|---|
| PL (1) | PL215042B1 (pl) |
| WO (1) | WO2010014022A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011157450A1 (en) | 2010-06-18 | 2011-12-22 | Krka, D. D., Novo Mesto | New polymorphic form of imatinib base and preparation of salts thereof |
| WO2013120852A1 (en) | 2012-02-13 | 2013-08-22 | Grindeks, A Joint Stock Company | Intermediates for a novel process of preparing imatinib and related tyrosine kinase inhibitors |
| WO2013136141A1 (en) * | 2012-03-13 | 2013-09-19 | Fresenius Kabi Oncology Ltd. | An improved process for the preparation of alpha form of imatinib mesylate |
| CN103980230B (zh) * | 2014-05-27 | 2016-02-17 | 西北大学 | 一种制备4-(4-甲基哌嗪-l-甲基)苯甲酰胺的方法 |
| CN106854198B (zh) * | 2015-12-08 | 2019-11-05 | 湖南华腾医药有限公司 | 一种伊马替尼的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW225528B (pl) * | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
| GB0202873D0 (en) * | 2002-02-07 | 2002-03-27 | Novartis Ag | Organic compounds |
| WO2004108699A1 (en) * | 2003-06-06 | 2004-12-16 | Natco Pharma Limited | Process for the preparation of the anti-cancer drug imatinib and its analogues |
| US8168787B2 (en) * | 2006-11-16 | 2012-05-01 | F.I.S. Fabbrica Italiana Sintetici S.P.A. | Process for the preparation of imatinib and intermediates thereof |
-
2008
- 2008-08-01 PL PL385805A patent/PL215042B1/pl unknown
-
2009
- 2009-07-30 WO PCT/PL2009/000077 patent/WO2010014022A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010014022A1 (en) | 2010-02-04 |
| PL215042B1 (pl) | 2013-10-31 |
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