PL3720879T3 - Terapia skojarzona przeciwciałami przeciwko progastynie i immunoterapią w leczeniu nowotworu - Google Patents
Terapia skojarzona przeciwciałami przeciwko progastynie i immunoterapią w leczeniu nowotworuInfo
- Publication number
- PL3720879T3 PL3720879T3 PL18829742.8T PL18829742T PL3720879T3 PL 3720879 T3 PL3720879 T3 PL 3720879T3 PL 18829742 T PL18829742 T PL 18829742T PL 3720879 T3 PL3720879 T3 PL 3720879T3
- Authority
- PL
- Poland
- Prior art keywords
- immunotherapy
- combination therapy
- treat cancer
- progastrin antibody
- progastrin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762594755P | 2017-12-05 | 2017-12-05 | |
| PCT/EP2018/083651 WO2019110662A1 (en) | 2017-12-05 | 2018-12-05 | Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3720879T3 true PL3720879T3 (pl) | 2022-09-12 |
Family
ID=64949216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18829742.8T PL3720879T3 (pl) | 2017-12-05 | 2018-12-05 | Terapia skojarzona przeciwciałami przeciwko progastynie i immunoterapią w leczeniu nowotworu |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11046758B2 (pl) |
| EP (1) | EP3720879B1 (pl) |
| JP (1) | JP7104153B2 (pl) |
| KR (1) | KR102461238B1 (pl) |
| CN (1) | CN111670197A (pl) |
| AU (1) | AU2018379320B2 (pl) |
| CA (1) | CA3084687C (pl) |
| DK (1) | DK3720879T3 (pl) |
| ES (1) | ES2920283T3 (pl) |
| PL (1) | PL3720879T3 (pl) |
| PT (1) | PT3720879T (pl) |
| SG (1) | SG11202005296SA (pl) |
| TW (1) | TWI763956B (pl) |
| WO (1) | WO2019110662A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102461238B1 (ko) * | 2017-12-05 | 2022-11-01 | 프로가스트린 에 캔서스 에스.에이 알.엘. | 암을 치료하기 위한 항-프로가스트린 항체와 면역치료 사이의 병용 치료 |
| CN112368579B (zh) * | 2018-02-27 | 2024-05-03 | Ecs前胃泌素股份有限公司 | 作为生物标记物的前胃泌素用于免疫疗法 |
| CN111171146B (zh) * | 2020-02-20 | 2022-03-04 | 西北农林科技大学 | 抗h9n2亚型禽流感病毒的纳米抗体、制备方法和应用 |
| EP4353746A4 (en) * | 2021-06-11 | 2024-12-04 | Guangdong Fapon Biopharma Inc. | Anti-pd-1 humanized antibody or antigen-binding fragment thereof and application thereof |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444887A (en) | 1979-12-10 | 1984-04-24 | Sloan-Kettering Institute | Process for making human antibody producing B-lymphocytes |
| US4716111A (en) | 1982-08-11 | 1987-12-29 | Trustees Of Boston University | Process for producing human antibodies |
| US4975278A (en) | 1988-02-26 | 1990-12-04 | Bristol-Myers Company | Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells |
| GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| GB8924581D0 (en) | 1989-11-01 | 1989-12-20 | Pa Consulting Services | Bleaching of hair |
| EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| EP0519596B1 (en) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5546806A (en) | 1991-10-17 | 1996-08-20 | Kain; Aron Z. | Microwave vector displacement and acceleration transducer |
| JPH05244982A (ja) | 1991-12-06 | 1993-09-24 | Sumitomo Chem Co Ltd | 擬人化b−b10 |
| ZA932522B (en) | 1992-04-10 | 1993-12-20 | Res Dev Foundation | Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens |
| US5792632A (en) | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| US5474896A (en) | 1992-05-05 | 1995-12-12 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| PT752248E (pt) | 1992-11-13 | 2001-01-31 | Idec Pharma Corp | Aplicacao terapeutica de anticorpos quimericos e marcados radioactivamente contra antigenios de diferenciacao restrita de linfocitos b humanos para o tratamento do linfoma de celulas b |
| DE69637481T2 (de) | 1995-04-27 | 2009-04-09 | Amgen Fremont Inc. | Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8 |
| EP0823941A4 (en) | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
| US5830729A (en) | 1996-04-18 | 1998-11-03 | Institut Pasteur | I Sce I-induced gene replacement and gene conversion in embryonic stem cells |
| US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| ES2301183T3 (es) | 1996-12-03 | 2008-06-16 | Amgen Fremont Inc. | Anticuerpo completamente humano que se une al receptor del egfr. |
| GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
| CN100387621C (zh) | 1997-04-14 | 2008-05-14 | 麦可麦脱股份公司 | 抗人抗原受体的新的生产方法及其用途 |
| US6235883B1 (en) | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
| DE60236182D1 (de) | 2001-09-14 | 2010-06-10 | Cellectis | Zufällige integration von polynukleotide nach in vivo linearisierung |
| EP1391213A1 (en) | 2002-08-21 | 2004-02-25 | Boehringer Ingelheim International GmbH | Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents |
| JP2006518372A (ja) | 2003-01-28 | 2006-08-10 | セレクティス | 脊椎動物の体組織においてエクスビボかつイントトで相同的組換えを誘発するためのメガヌクレアーゼの使用およびその応用 |
| DK1794586T3 (da) | 2004-09-22 | 2013-05-13 | Cancer Advances Inc | Monoklonale antistoffer til progastrin |
| WO2009054985A1 (en) | 2007-10-25 | 2009-04-30 | Sangamo Biosciences, Inc. | Methods and compositions for targeted integration |
| UA106771C2 (uk) * | 2009-10-16 | 2014-10-10 | Ле Лаборатуар Сервьє | Моноклональні антитіла до прогастрину та їх використання |
| US9487582B2 (en) * | 2010-01-08 | 2016-11-08 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods for treating pancreatic cancer |
| US9217032B2 (en) * | 2010-01-08 | 2015-12-22 | Les Laboratoires Servier | Methods for treating colorectal cancer |
| ES2754774T3 (es) * | 2010-03-24 | 2020-04-20 | Progastrine Et Cancers S A R L | Profilaxis de cáncer colorrectal y gastrointestinal |
| AU2011284908B2 (en) * | 2010-07-26 | 2015-05-21 | Centre National De La Recherche Scientifique (Cnrs) | Methods and compositions for liver cancer therapy |
| JOP20200094A1 (ar) * | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| WO2016069727A1 (en) * | 2014-10-29 | 2016-05-06 | Five Prime Therapeutics, Inc. | Combination therapy for cancer |
| EA037027B1 (ru) * | 2015-12-31 | 2021-01-27 | Прогастрин Э Кансер С.А Р.Л. | Применение и способ для профилактики или лечения рака желудка с использованием композиции, содержащей моноклональное прогастринсвязывающее антитело |
| BR112018013272A2 (pt) * | 2015-12-31 | 2018-12-11 | Progastrine Et Cancers S A R L | composições e métodos para detectar e tratar câncer esofágico |
| CN108780091A (zh) * | 2015-12-31 | 2018-11-09 | 普莱戈斯瑞恩癌症有限责任公司 | 用于检测和治疗卵巢癌的组合物和方法 |
| CN110945025B (zh) * | 2017-03-30 | 2023-11-03 | Ecs前胃泌素股份有限公司 | 用于检测前列腺癌的组合物和方法 |
| CA3058270C (en) * | 2017-03-30 | 2023-07-18 | Ecs-Progastrin Sa | Compositions and methods for detecting lung cancer |
| EP3624841A4 (en) * | 2017-06-15 | 2021-01-27 | Cancer Advances, Inc., | COMPOSITIONS AND METHODS FOR INDUCING HUMORAL AND CELLULAR IMMUNITIES AGAINST TUMORS AND CANCER |
| KR102461238B1 (ko) * | 2017-12-05 | 2022-11-01 | 프로가스트린 에 캔서스 에스.에이 알.엘. | 암을 치료하기 위한 항-프로가스트린 항체와 면역치료 사이의 병용 치료 |
| CN112368579B (zh) * | 2018-02-27 | 2024-05-03 | Ecs前胃泌素股份有限公司 | 作为生物标记物的前胃泌素用于免疫疗法 |
-
2018
- 2018-12-05 KR KR1020207019218A patent/KR102461238B1/ko active Active
- 2018-12-05 US US16/769,844 patent/US11046758B2/en active Active
- 2018-12-05 AU AU2018379320A patent/AU2018379320B2/en active Active
- 2018-12-05 PT PT188297428T patent/PT3720879T/pt unknown
- 2018-12-05 TW TW107143746A patent/TWI763956B/zh active
- 2018-12-05 EP EP18829742.8A patent/EP3720879B1/en active Active
- 2018-12-05 JP JP2020530573A patent/JP7104153B2/ja active Active
- 2018-12-05 DK DK18829742.8T patent/DK3720879T3/da active
- 2018-12-05 CA CA3084687A patent/CA3084687C/en active Active
- 2018-12-05 ES ES18829742T patent/ES2920283T3/es active Active
- 2018-12-05 PL PL18829742.8T patent/PL3720879T3/pl unknown
- 2018-12-05 CN CN201880088139.2A patent/CN111670197A/zh active Pending
- 2018-12-05 WO PCT/EP2018/083651 patent/WO2019110662A1/en not_active Ceased
- 2018-12-05 SG SG11202005296SA patent/SG11202005296SA/en unknown
-
2021
- 2021-06-25 US US17/358,480 patent/US12180275B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK3720879T3 (da) | 2022-06-20 |
| AU2018379320A1 (en) | 2020-07-02 |
| CA3084687C (en) | 2024-01-02 |
| KR20200118409A (ko) | 2020-10-15 |
| US20210324069A1 (en) | 2021-10-21 |
| US12180275B2 (en) | 2024-12-31 |
| EP3720879A1 (en) | 2020-10-14 |
| ES2920283T3 (es) | 2022-08-02 |
| TW201927805A (zh) | 2019-07-16 |
| CN111670197A (zh) | 2020-09-15 |
| RU2020121176A3 (pl) | 2022-04-27 |
| JP2021505576A (ja) | 2021-02-18 |
| TWI763956B (zh) | 2022-05-11 |
| PT3720879T (pt) | 2022-07-13 |
| EP3720879B1 (en) | 2022-05-11 |
| SG11202005296SA (en) | 2020-07-29 |
| JP7104153B2 (ja) | 2022-07-20 |
| WO2019110662A1 (en) | 2019-06-13 |
| US11046758B2 (en) | 2021-06-29 |
| AU2018379320B2 (en) | 2023-06-15 |
| CA3084687A1 (en) | 2019-06-13 |
| RU2020121176A (ru) | 2022-01-10 |
| KR102461238B1 (ko) | 2022-11-01 |
| US20210009680A1 (en) | 2021-01-14 |
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