PL378135A1 - 2-Cyjanopirolopirymidyny i ich zastosowania w farmaceutykach - Google Patents
2-Cyjanopirolopirymidyny i ich zastosowania w farmaceutykachInfo
- Publication number
- PL378135A1 PL378135A1 PL378135A PL37813504A PL378135A1 PL 378135 A1 PL378135 A1 PL 378135A1 PL 378135 A PL378135 A PL 378135A PL 37813504 A PL37813504 A PL 37813504A PL 378135 A1 PL378135 A1 PL 378135A1
- Authority
- PL
- Poland
- Prior art keywords
- cyanopyrrolopyrimidines
- pharmaceutical uses
- pharmaceutical
- Prior art date
Links
- WTPFGNCJZHVQBG-UHFFFAOYSA-N N1C(C#N)=NC=C2N=CC=C21 Chemical class N1C(C#N)=NC=C2N=CC=C21 WTPFGNCJZHVQBG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0302748A GB0302748D0 (en) | 2003-02-06 | 2003-02-06 | Organic compounds |
| GB0304641A GB0304641D0 (en) | 2003-02-28 | 2003-02-28 | Organic compounds |
| GB0304642A GB0304642D0 (en) | 2003-02-28 | 2003-02-28 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL378135A1 true PL378135A1 (pl) | 2006-03-06 |
Family
ID=32854008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL378135A PL378135A1 (pl) | 2003-02-06 | 2004-02-05 | 2-Cyjanopirolopirymidyny i ich zastosowania w farmaceutykach |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20060247251A1 (pl) |
| EP (1) | EP1592426B1 (pl) |
| JP (1) | JP4499667B2 (pl) |
| AR (1) | AR043692A1 (pl) |
| AT (1) | ATE381335T1 (pl) |
| AU (1) | AU2004210422B2 (pl) |
| BR (1) | BRPI0407327A (pl) |
| CA (1) | CA2514287A1 (pl) |
| DE (1) | DE602004010785T2 (pl) |
| ES (1) | ES2297378T3 (pl) |
| MX (1) | MXPA05008348A (pl) |
| PE (1) | PE20050068A1 (pl) |
| PL (1) | PL378135A1 (pl) |
| PT (1) | PT1592426E (pl) |
| TW (1) | TW200420566A (pl) |
| WO (1) | WO2004069256A1 (pl) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0201980D0 (sv) | 2002-06-24 | 2002-06-24 | Astrazeneca Ab | Novel compounds |
| GB0304640D0 (en) * | 2003-02-28 | 2003-04-02 | Novartis Ag | Organic compounds |
| EP1797883A3 (en) * | 2003-04-28 | 2007-08-01 | Novartis AG | Pharmaceutical composition comprising a cathepsin S inhibitor and an opioid |
| AU2005243238B2 (en) * | 2004-05-03 | 2011-11-10 | Janssen Pharmaceutica N.V. | Novel indole derivatives as selective androgen receptor modulators (SARMS) |
| US9107864B2 (en) | 2004-06-07 | 2015-08-18 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to treat cancers |
| US8501198B2 (en) | 2004-06-07 | 2013-08-06 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to treat cancers |
| HRP20140754T2 (hr) | 2009-06-29 | 2015-07-17 | Incyte Corporation | Pirimidinoni kao inhibitori pi3k |
| US8759359B2 (en) | 2009-12-18 | 2014-06-24 | Incyte Corporation | Substituted heteroaryl fused derivatives as PI3K inhibitors |
| UY33304A (es) * | 2010-04-02 | 2011-10-31 | Amgen Inc | Compuestos heterocíclicos y sus usos |
| WO2011130342A1 (en) | 2010-04-14 | 2011-10-20 | Incyte Corporation | FUSED DERIVATIVES AS ΡI3Κδ INHIBITORS |
| US9062055B2 (en) | 2010-06-21 | 2015-06-23 | Incyte Corporation | Fused pyrrole derivatives as PI3K inhibitors |
| ES2645509T3 (es) | 2010-07-26 | 2017-12-05 | Qu Biologics Inc | Composiciones antiinflamatorias inmunogénicas |
| TWI527814B (zh) | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI501967B (zh) | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| WO2012087881A1 (en) | 2010-12-20 | 2012-06-28 | Incyte Corporation | N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors |
| WO2012125629A1 (en) | 2011-03-14 | 2012-09-20 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors |
| WO2012135009A1 (en) | 2011-03-25 | 2012-10-04 | Incyte Corporation | Pyrimidine-4,6-diamine derivatives as pi3k inhibitors |
| LT3196202T (lt) | 2011-09-02 | 2019-07-10 | Incyte Holdings Corporation | Heterociklilaminai, kaip pi3k slopikliai |
| CN103304525B (zh) * | 2012-03-08 | 2015-08-05 | 深圳海王药业有限公司 | 一种制备达非那新中间体5-(卤代乙基)-2,3-二氢苯并呋喃的方法 |
| AR090548A1 (es) | 2012-04-02 | 2014-11-19 | Incyte Corp | Azaheterociclobencilaminas biciclicas como inhibidores de pi3k |
| US9328118B2 (en) * | 2012-04-17 | 2016-05-03 | Astellas Pharma Inc. | Nitrogen-containing bicyclic aromatic heterocyclic compound |
| US20150111868A1 (en) | 2012-06-15 | 2015-04-23 | Jansen R&D Ireland | Novel 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents |
| BR112015008325B1 (pt) | 2012-10-16 | 2022-01-25 | Janssen Sciences Ireland Uc | Compostos antivirais contra o rsv, seu uso e composição farmacêutica que os compreende |
| JP6387391B2 (ja) * | 2013-03-14 | 2018-09-05 | ノバルティス アーゲー | 眼科疾患の処置に有用な補体因子Ｂ阻害剤としての２−（１Ｈ−インドール−４−イルメチル）−３Ｈ−イミダゾ［４，５−ｂ］ピリジン−６−カルボニトリル誘導体 |
| EP3089963A1 (en) | 2013-10-30 | 2016-11-09 | Novartis AG | 2-benzyl-benzimidazole complement factor b inhibitors and uses thereof |
| TWI671299B (zh) | 2014-04-14 | 2019-09-11 | 愛爾蘭商健生科學愛爾蘭無限公司 | 作為ｒｓｖ抗病毒化合物之螺脲化合物 |
| CA3254723A1 (en) | 2014-05-02 | 2025-04-15 | Qu Biologics Inc | ANTIMICROBIAL IMMUNOMODULATION |
| US10077277B2 (en) | 2014-06-11 | 2018-09-18 | Incyte Corporation | Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors |
| CN117736209A (zh) | 2015-02-27 | 2024-03-22 | 因赛特控股公司 | Pi3k抑制剂的盐及其制备方法 |
| US10537552B2 (en) | 2015-05-05 | 2020-01-21 | Carafe Drug Innovation, Llc | Substituted 5-hydroxyoxindoles and their use as analgesics and fever reducers |
| WO2016183063A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Crystalline forms of a pi3k inhibitor |
| US9732097B2 (en) | 2015-05-11 | 2017-08-15 | Incyte Corporation | Process for the synthesis of a phosphoinositide 3-kinase inhibitor |
| BR112020008371A2 (pt) * | 2017-10-27 | 2020-11-03 | Esteve Pharmaceuticals, S.A. | novos derivados de alcoxiamino para tratamento de dor e condições relacionadas à dor |
| PE20211208A1 (es) | 2018-06-01 | 2021-07-05 | Incyte Corp | Regimen de dosificacion para el tratamiento de trastornos relacionados con pi3k |
| WO2020048829A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 3,9-diazaspiro[5.5]undecane compounds |
| WO2021250180A1 (en) | 2020-06-11 | 2021-12-16 | Janssen Sciences Ireland Unlimited Company | Hemi (l)-tartrate forms of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1h-indol-2 yl} methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2h-imidazo[4,5-c]pyridin-2-one and pharmaceutical compositions comprising the same |
| CN116396202A (zh) * | 2023-04-17 | 2023-07-07 | 南京优氟医药科技有限公司 | 一种（2s，4s）-4-氟代吡咯烷-2-羧酸的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0888353B1 (de) * | 1996-03-15 | 2003-07-09 | Novartis AG | N-7 HETEROCYCLYL-PYRROLO[ 2,3-d]PYRIMIDINE UND IHRE VERWENDUNG |
| ATE347362T1 (de) * | 1998-06-30 | 2006-12-15 | Lilly Co Eli | Bicyclische spla 2-inhibitoren |
| GB0100622D0 (en) * | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds V111 |
| US20030144234A1 (en) * | 2001-08-30 | 2003-07-31 | Buxton Francis Paul | Methods for the treatment of chronic pain and compositions therefor |
| GB0121033D0 (en) * | 2001-08-30 | 2001-10-24 | Novartis Ag | Organic compounds |
-
2004
- 2004-02-04 AR ARP040100349A patent/AR043692A1/es unknown
- 2004-02-04 PE PE2004000127A patent/PE20050068A1/es not_active Application Discontinuation
- 2004-02-05 BR BR0407327-4A patent/BRPI0407327A/pt not_active IP Right Cessation
- 2004-02-05 EP EP04708332A patent/EP1592426B1/en not_active Expired - Lifetime
- 2004-02-05 ES ES04708332T patent/ES2297378T3/es not_active Expired - Lifetime
- 2004-02-05 AU AU2004210422A patent/AU2004210422B2/en not_active Ceased
- 2004-02-05 DE DE602004010785T patent/DE602004010785T2/de not_active Expired - Fee Related
- 2004-02-05 US US10/544,694 patent/US20060247251A1/en not_active Abandoned
- 2004-02-05 PL PL378135A patent/PL378135A1/pl not_active Application Discontinuation
- 2004-02-05 MX MXPA05008348A patent/MXPA05008348A/es active IP Right Grant
- 2004-02-05 JP JP2005518660A patent/JP4499667B2/ja not_active Expired - Fee Related
- 2004-02-05 PT PT04708332T patent/PT1592426E/pt unknown
- 2004-02-05 TW TW093102603A patent/TW200420566A/zh unknown
- 2004-02-05 AT AT04708332T patent/ATE381335T1/de not_active IP Right Cessation
- 2004-02-05 WO PCT/EP2004/001081 patent/WO2004069256A1/en not_active Ceased
- 2004-02-05 CA CA002514287A patent/CA2514287A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006516554A (ja) | 2006-07-06 |
| MXPA05008348A (es) | 2005-11-04 |
| DE602004010785T2 (de) | 2008-12-04 |
| JP4499667B2 (ja) | 2010-07-07 |
| CA2514287A1 (en) | 2004-08-19 |
| AU2004210422A1 (en) | 2004-08-19 |
| ATE381335T1 (de) | 2008-01-15 |
| TW200420566A (en) | 2004-10-16 |
| EP1592426B1 (en) | 2007-12-19 |
| AR043692A1 (es) | 2005-08-10 |
| EP1592426A1 (en) | 2005-11-09 |
| ES2297378T3 (es) | 2008-05-01 |
| HK1084883A1 (en) | 2006-08-11 |
| PE20050068A1 (es) | 2005-03-11 |
| WO2004069256A1 (en) | 2004-08-19 |
| BRPI0407327A (pt) | 2006-01-10 |
| AU2004210422B2 (en) | 2008-01-17 |
| DE602004010785D1 (de) | 2008-01-31 |
| PT1592426E (pt) | 2008-03-13 |
| US20060247251A1 (en) | 2006-11-02 |
| WO2004069256A8 (en) | 2004-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |