PL3774862T3 - Novel glp-1 analogues - Google Patents

Novel glp-1 analogues

Info

Publication number: PL3774862T3
Authority: PL; Poland
Prior art keywords: analogues; novel glp; glp; novel
Prior art date: 2018-04-05

Application number

PL19724915.4T

Other languages

Polish (pl)

Inventor

Rajamannar Thennati

Nishith Chaturvedi

Vinod Sampatrao BURADE

Pradeep Dinesh SHAHI

Muthukumaran Natarajan

Ravishankara Madavati NAGARAJA

Rishit Mansukhlal ZALAWADIA

Kunal PANDYA

Brijeshkumar PATEL

Dhiren Rameshchandra JOSHI

Krunal Harishbhai SONI

Abhishek Tiwari

Vipulkumar Shankarbhai PATEL

Original Assignee

Sun Pharmaceutical Industries Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-04-05

Filing date

2019-04-05

Publication date

2022-10-03

2019-04-05 Application filed by Sun Pharmaceutical Industries Limited filed Critical Sun Pharmaceutical Industries Limited

2022-10-03 Publication of PL3774862T3 publication Critical patent/PL3774862T3/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Immunology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Transmission And Conversion Of Sensor Element Output (AREA)

PL19724915.4T 2018-04-05 2019-04-05 Novel glp-1 analogues PL3774862T3 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
IN201821013109		2018-04-05
IN201821040474		2018-10-26
IN201821040468		2018-10-26
PCT/IB2019/052835 WO2019193576A1 (en)	2018-04-05	2019-04-05	Novel glp-1 analogues

Publications (1)

Publication Number	Publication Date
PL3774862T3 true PL3774862T3 (en)	2022-10-03

Family

ID=66589592

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL19724915.4T PL3774862T3 (en)	2018-04-05	2019-04-05	Novel glp-1 analogues
PL22177403.7T PL4122954T3 (en)	2018-04-05	2019-04-05	Novel glp-1 analogues

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL22177403.7T PL4122954T3 (en)	2018-04-05	2019-04-05	Novel glp-1 analogues

Country Status (33)

Country	Link
US (7)	US11447535B2 (en)
EP (3)	EP3774862B1 (en)
JP (2)	JP7250814B2 (en)
KR (2)	KR20250065720A (en)
CN (3)	CN117964735A (en)
AU (3)	AU2019247936C1 (en)
BR (1)	BR112020020419A2 (en)
CA (1)	CA3095988A1 (en)
CL (1)	CL2020002574A1 (en)
CO (1)	CO2020012425A2 (en)
DK (2)	DK4122954T3 (en)
EC (1)	ECSP20070185A (en)
ES (2)	ES2980707T3 (en)
FI (1)	FI4122954T3 (en)
HR (2)	HRP20240749T1 (en)
HU (2)	HUE060135T2 (en)
IL (1)	IL277483A (en)
JO (1)	JOP20200251A1 (en)
LT (2)	LT3774862T (en)
MX (2)	MX2020010505A (en)
MY (1)	MY202560A (en)
NZ (1)	NZ768446A (en)
PE (1)	PE20211417A1 (en)
PH (1)	PH12020551591A1 (en)
PL (2)	PL3774862T3 (en)
PT (2)	PT4122954T (en)
RS (2)	RS65639B1 (en)
SG (1)	SG11202009467YA (en)
SI (2)	SI4122954T1 (en)
SM (2)	SMT202400241T1 (en)
UA (1)	UA128210C2 (en)
WO (1)	WO2019193576A1 (en)
ZA (1)	ZA202306729B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20250065720A (en) *	2018-04-05	2025-05-13	썬 파마슈티칼 인더스트리스 리미티드	Novel glp-1 analogues
TWI829687B (en)	2018-05-07	2024-01-21	丹麥商諾佛儂迪克股份有限公司	Solid compositions comprising a glp-1 agonist and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid
TW202216746A (en) *	2020-06-22	2022-05-01	印度商太陽製藥工業有限公司	Long acting glp-1/gip dual agonists
TW202229323A (en) *	2020-10-17	2022-08-01	印度商太陽製藥工業有限公司	Novel glp-1/gip dual agonists
CN114685646B (en) *	2020-12-31	2023-04-07	厦门赛诺邦格生物科技股份有限公司	Preparation method and application of polypeptide side chain analogue
CA3204051A1 (en)	2021-01-20	2022-07-28	Brian Lian	Compositions and methods for the treatment of metabolic and liver disorders
IL311411A (en)	2021-09-15	2024-05-01	Viking Therapeutics Inc	Compositions and methods for the treatment of metabolic and liver disorders
IL312672A (en) *	2021-11-10	2024-07-01	I2O Therapeutics Inc	Ionic liquid compositions
CN115785249B (en) *	2022-10-13	2023-07-21	江苏师范大学	A class of GLP-1 analogues and their applications
WO2024252366A1 (en)	2023-06-09	2024-12-12	Sun Pharmaceutical Industries Limited	Glp-1/gip dual, glp-1/gcg dual and glp-1/gip/gcg triple receptor agonists
WO2024261580A1 (en)	2023-06-20	2024-12-26	Sun Pharmaceutical Industries Limited	Glp-1 analog for use in the treatment of metabolic disorders
CN117756914B (en) *	2023-12-15	2024-09-03	瀚晖制药有限公司	Preparation method of lithocarpic insulin
WO2025163615A1 (en)	2024-01-31	2025-08-07	Sun Pharmaceutical Industries Ltd.	High level production of glp1 analogues

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6849708B1 (en)	1986-05-05	2005-02-01	The General Hospital Corporation	Insulinotropic hormone and uses thereof
CZ300837B6 (en)	1996-08-30	2009-08-26	Novo Nordisk A/S	GLP-1 (7-37) derivatives or analogs thereof, pharmaceutical composition in which the derivatives are comprised as well as their use
US6268343B1 (en)	1996-08-30	2001-07-31	Novo Nordisk A/S	Derivatives of GLP-1 analogs
WO1999043705A1 (en)	1998-02-27	1999-09-02	Novo Nordisk A/S	N-terminally truncated glp-1 derivatives
WO1999043708A1 (en)	1998-02-27	1999-09-02	Novo Nordisk A/S	Glp-1 derivatives of glp-1 and exendin with protracted profile of action
EP1062240B1 (en)	1998-02-27	2010-04-28	Novo Nordisk A/S	N-terminally modified glp-1 derivatives
DE69942306D1 (en)	1998-02-27	2010-06-10	Novo Nordisk As	ABSTRACT OF GLP-1 ANALOG
FR2777283B1 (en)	1998-04-10	2000-11-24	Adir	NOVEL GLUCAGON-PEPTIDE- 1 (7-37) ANALOGUE PEPTIDE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
RU2214418C2 (en)	1998-12-07	2003-10-20	Сосьете Де Консей Де Решерш Э Д'Аппликасьон Сьентифик Сас	Glp-1 analogs
PT1695983E (en)	2000-06-16	2009-05-05	Lilly Co Eli	Glucagon-like peptide-1 analogs
MXPA03005036A (en)	2000-12-07	2003-09-05	Lilly Co Eli	Glp-1 fusion proteins.
EP1585959A4 (en)	2002-01-08	2007-11-14	Lilly Co Eli	Extended glucagon-like peptide-1 analogs
JPWO2004037859A1 (en)	2002-10-11	2006-02-23	株式会社三和化学研究所	GLP-1 derivative and transmucosal absorption preparation thereof
EP1626981A4 (en)	2003-03-04	2006-11-22	Biorexis Pharmaceutical Corp	Dipeptidyl-peptidase protected proteins
EP1633384B1 (en)	2003-05-15	2012-03-14	Trustees Of Tufts College	Stable analogs of glp-1
TW200526254A (en)	2003-09-19	2005-08-16	Novo Nordisk As	Novel GLP-1 derivatives
CA2551039C (en)	2003-12-16	2013-01-29	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R	Analogues of glp-1
JP2008515856A (en)	2004-10-07	2008-05-15	ノボノルディスクアクティーゼルスカブ	Delayed GLP-1 compound
MX2007011307A (en) *	2005-03-18	2007-10-08	Novo Nordisk As	Extended glp-1 compounds.
TWI362392B (en) *	2005-03-18	2012-04-21	Novo Nordisk As	Acylated glp-1 compounds
EP1883419A4 (en)	2005-05-06	2010-08-04	Bayer Pharmaceuticals Corp	Glucagon-like peptide 1 (glp-1) receptor agonists and their pharmacological methods of use
US8318668B2 (en)	2005-09-08	2012-11-27	Trustees Of Tufts College	Stabilized GLP-1 analogs
ES2336575T3 (en)	2005-09-22	2010-04-14	Biocompatibles Uk Limited	GLP-1 FUSION POLYPEPTIDES (PEPTIDE-1 SIMILAR TO GLUCAGON) WITH INCREASED RESISTANCE TO PEPTIDASE.
ES2532116T3 (en)	2007-09-05	2015-03-24	Novo Nordisk A/S	Peptides derived with A-B-C-D and their therapeutic uses
ES2558155T3 (en)	2007-10-30	2016-02-02	Indiana University Research And Technology Corporation	Compounds showing glucacon antagonist activity and GLP-1 agonist
WO2011080103A1 (en)	2009-12-16	2011-07-07	Novo Nordisk A/S	Double-acylated glp-1 derivatives
CA2797431C (en)	2010-04-27	2016-06-21	Zhejiang Beta Pharma Inc.	Glucagon-like peptide-1 analogue and use thereof
WO2012016419A1 (en)	2010-08-06	2012-02-09	浙江贝达药业有限公司	Glp-1 derivatives and uses thereof
CN103209711B (en)	2010-11-09	2016-04-13	诺沃—诺迪斯克有限公司	Bis-acylated GLP-1 derivatives
DK2696687T3 (en)	2011-04-12	2017-02-06	Novo Nordisk As	Double-acylated GLP-1 derivatives
WO2012150503A2 (en)	2011-05-03	2012-11-08	Zealand Pharma A/S	Glu-glp-1 dual agonist signaling-selective compounds
US9758560B2 (en)	2011-09-06	2017-09-12	Novo Nordisk A/S	GLP-1 derivatives
EP2578599A1 (en)	2011-10-07	2013-04-10	LanthioPep B.V.	Cyclic analogs of GLP-1 and GLP-1 related peptides
ES2629735T3 (en)	2012-05-08	2017-08-14	Novo Nordisk A/S	Double-acylated GLP-1 derivatives
EP2846823B1 (en)	2012-05-08	2019-12-04	Novo Nordisk A/S	Double-acylated glp-1 derivatives
AR091422A1 (en)	2012-06-14	2015-02-04	Sanofi Sa	PEPTIDIC ANALOGS OF EXENDINA 4
UA116217C2 (en)	2012-10-09	2018-02-26	Санофі	Exendin-4 derivatives as dual glp1/glucagon agonists
TWI674270B (en)	2012-12-11	2019-10-11	英商梅迪繆思有限公司	Glucagon and glp-1 co-agonists for the treatment of obesity
HRP20181300T1 (en)	2012-12-21	2018-10-05	Sanofi	Exendin-4 derivatives as dual glp1/gip/glucagon agonists
MX2015016564A (en)	2013-06-20	2016-04-15	Novo Nordisk As	Glp-1 derivatives and uses thereof.
WO2014209886A1 (en)	2013-06-23	2014-12-31	Wisconsin Alumni Research Foundation	Alpha/beta-polypeptide analogs of glucagon-like peptid-1
AU2014286234A1 (en)	2013-07-04	2015-12-17	Novo Nordisk A/S	Derivatives of GLP-1 like peptides, and uses thereof
EP3033112B1 (en)	2013-08-15	2020-10-07	Novo Nordisk A/S	Glp-1 derivatives, and uses thereof
AP2016009212A0 (en) *	2013-10-17	2016-05-31	Zealand Pharma As	Acylated glucagon analogues
WO2015086731A1 (en)	2013-12-13	2015-06-18	Sanofi	Exendin-4 peptide analogues as dual glp-1/glucagon receptor agonists
MX2016007407A (en)	2013-12-13	2016-12-12	Medimmune Ltd	Protease resistant peptides.
EP3080149A1 (en)	2013-12-13	2016-10-19	Sanofi	Dual glp-1/glucagon receptor agonists
CN106999602B (en)	2014-11-27	2022-02-01	诺和诺德股份有限公司	GLP-1 derivatives and uses thereof
WO2016097108A1 (en)	2014-12-17	2016-06-23	Novo Nordisk A/S	Glp-1 derivatives and uses thereof
TWI726889B (en)	2015-06-10	2021-05-11	英商梅迪繆思有限公司	Protease-resistant lipidated peptides
US10111932B2 (en)	2015-08-26	2018-10-30	Syracuse University	Coagonists of glucagon-like peptide 1 receptor and neuropeptide Y2 receptor
JP7053480B2 (en)	2016-03-03	2022-04-12	ノヴォノルディスクアー／エス	GLP-1 derivative and its use
CN109195984A (en)	2016-06-09	2019-01-11	免疫医疗有限公司	The mono- esterified peptide of protease resistant
JP7076442B2 (en)	2016-11-07	2022-05-27	ノヴォノルディスクアー／エス	DCHBS active ester of PEG compound and its use
TW201833131A (en)	2016-12-02	2018-09-16	法商賽諾菲公司	New compounds as peptidic glp1/glucagon/gip receptor agonists
WO2018178796A1 (en) *	2017-03-27	2018-10-04	Sun Pharmaceutical Industries Limited	Method for making kex1 protease sensitive polypeptides using yeast strain
EP3704143B1 (en)	2018-03-09	2023-10-18	Fresenius Kabi iPSUM S.r.l.	Chemo-enzymatic synthesis of liraglutide, semaglutide and glp-1
KR20250065720A (en) *	2018-04-05	2025-05-13	썬 파마슈티칼 인더스트리스 리미티드	Novel glp-1 analogues

2019
- 2019-04-05 KR KR1020257013603A patent/KR20250065720A/en active Pending
- 2019-04-05 PL PL19724915.4T patent/PL3774862T3/en unknown
- 2019-04-05 NZ NZ768446A patent/NZ768446A/en unknown
- 2019-04-05 US US16/376,190 patent/US11447535B2/en active Active
- 2019-04-05 SM SM20240241T patent/SMT202400241T1/en unknown
- 2019-04-05 LT LTEPPCT/IB2019/052835T patent/LT3774862T/en unknown
- 2019-04-05 CN CN202311777728.0A patent/CN117964735A/en active Pending
- 2019-04-05 RS RS20240706A patent/RS65639B1/en unknown
- 2019-04-05 BR BR112020020419-6A patent/BR112020020419A2/en unknown
- 2019-04-05 HU HUE19724915A patent/HUE060135T2/en unknown
- 2019-04-05 AU AU2019247936A patent/AU2019247936C1/en active Active
- 2019-04-05 SI SI201930764T patent/SI4122954T1/en unknown
- 2019-04-05 ES ES22177403T patent/ES2980707T3/en active Active
- 2019-04-05 EP EP19724915.4A patent/EP3774862B1/en active Active
- 2019-04-05 CA CA3095988A patent/CA3095988A1/en active Pending
- 2019-04-05 CN CN201980037166.1A patent/CN112236444B/en active Active
- 2019-04-05 CN CN202510743440.4A patent/CN120554480A/en active Pending
- 2019-04-05 JO JOP/2020/0251A patent/JOP20200251A1/en unknown
- 2019-04-05 SI SI201930322T patent/SI3774862T1/en unknown
- 2019-04-05 EP EP22177403.7A patent/EP4122954B1/en active Active
- 2019-04-05 PL PL22177403.7T patent/PL4122954T3/en unknown
- 2019-04-05 PE PE2020001535A patent/PE20211417A1/en unknown
- 2019-04-05 SG SG11202009467YA patent/SG11202009467YA/en unknown
- 2019-04-05 DK DK22177403.7T patent/DK4122954T3/en active
- 2019-04-05 PT PT221774037T patent/PT4122954T/en unknown
- 2019-04-05 WO PCT/IB2019/052835 patent/WO2019193576A1/en not_active Ceased
- 2019-04-05 KR KR1020207031696A patent/KR102801994B1/en active Active
- 2019-04-05 SM SM20220352T patent/SMT202200352T1/en unknown
- 2019-04-05 FI FIEP22177403.7T patent/FI4122954T3/en active
- 2019-04-05 UA UAA202006178A patent/UA128210C2/en unknown
- 2019-04-05 HR HRP20240749TT patent/HRP20240749T1/en unknown
- 2019-04-05 JP JP2020553627A patent/JP7250814B2/en active Active
- 2019-04-05 HR HRP20221054TT patent/HRP20221054T1/en unknown
- 2019-04-05 LT LTEP22177403.7T patent/LT4122954T/en unknown
- 2019-04-05 EP EP24161843.8A patent/EP4364751A3/en active Pending
- 2019-04-05 PT PT197249154T patent/PT3774862T/en unknown
- 2019-04-05 RS RS20220814A patent/RS63523B1/en unknown
- 2019-04-05 DK DK19724915.4T patent/DK3774862T3/en active
- 2019-04-05 ES ES19724915T patent/ES2925678T3/en active Active
- 2019-04-05 MX MX2020010505A patent/MX2020010505A/en unknown
- 2019-04-05 HU HUE22177403A patent/HUE067499T2/en unknown
- 2019-04-05 MY MYPI2020004864A patent/MY202560A/en unknown
2020
- 2020-08-04 US US16/985,207 patent/US11242373B2/en active Active
- 2020-09-21 IL IL277483A patent/IL277483A/en unknown
- 2020-09-29 PH PH12020551591A patent/PH12020551591A1/en unknown
- 2020-10-02 CO CONC2020/0012425A patent/CO2020012425A2/en unknown
- 2020-10-05 MX MX2024007688A patent/MX2024007688A/en unknown
- 2020-10-05 CL CL2020002574A patent/CL2020002574A1/en unknown
- 2020-11-05 EC ECSENADI202070185A patent/ECSP20070185A/en unknown
- 2020-12-28 US US17/134,982 patent/US11485766B2/en active Active
2022
- 2022-08-01 US US17/816,577 patent/US11873328B2/en active Active
- 2022-08-12 US US17/819,466 patent/US11866477B2/en active Active
2023
- 2023-03-22 JP JP2023045498A patent/JP2023078367A/en active Pending
- 2023-06-01 AU AU2023203430A patent/AU2023203430B2/en active Active
- 2023-06-30 ZA ZA2023/06729A patent/ZA202306729B/en unknown
- 2023-11-21 US US18/515,712 patent/US12421289B2/en active Active
2024
- 2024-05-17 US US18/667,531 patent/US20240376175A1/en active Pending
2025
- 2025-10-02 AU AU2025242190A patent/AU2025242190A1/en active Pending

Also Published As

Publication number	Publication date
ES2925678T3 (en)	2022-10-19
UA128210C2 (en)	2024-05-08
JP2023078367A (en)	2023-06-06
SI4122954T1 (en)	2024-07-31
CA3095988A1 (en)	2019-10-10
EP3774862A1 (en)	2021-02-17
CN112236444A (en)	2021-01-15
LT3774862T (en)	2022-09-12
RS65639B1 (en)	2024-07-31
RS63523B1 (en)	2022-09-30
KR102801994B1 (en)	2025-04-30
US20240199718A1 (en)	2024-06-20
SMT202200352T1 (en)	2022-09-14
AU2023203430A1 (en)	2023-06-29
JP7250814B2 (en)	2023-04-03
DK3774862T3 (en)	2022-09-05
EP4122954A1 (en)	2023-01-25
KR20250065720A (en)	2025-05-13
SMT202400241T1 (en)	2024-07-09
AU2019247936B2 (en)	2023-03-02
EP4364751A3 (en)	2024-06-26
FI4122954T3 (en)	2024-06-18
PH12020551591A1 (en)	2021-08-16
SG11202009467YA (en)	2020-10-29
MY202560A (en)	2024-05-08
US11242373B2 (en)	2022-02-08
AU2019247936A1 (en)	2020-10-15
ES2980707T3 (en)	2024-10-02
BR112020020419A2 (en)	2021-01-19
KR20200141469A (en)	2020-12-18
EP4364751A2 (en)	2024-05-08
US12421289B2 (en)	2025-09-23
EP4122954B1 (en)	2024-04-03
ECSP20070185A (en)	2021-01-29
US11485766B2 (en)	2022-11-01
HRP20221054T1 (en)	2022-11-11
ZA202306729B (en)	2024-03-27
US20220402992A1 (en)	2022-12-22
US20240376175A1 (en)	2024-11-14
IL277483A (en)	2020-11-30
AU2019247936C1 (en)	2023-06-15
HUE060135T2 (en)	2023-02-28
CN120554480A (en)	2025-08-29
US20210206823A1 (en)	2021-07-08
SI3774862T1 (en)	2022-10-28
CO2020012425A2 (en)	2020-12-21
US20220402991A1 (en)	2022-12-22
PL4122954T3 (en)	2024-08-12
CN112236444B (en)	2025-09-19
HRP20240749T1 (en)	2024-09-13
PT3774862T (en)	2022-09-05
LT4122954T (en)	2024-06-25
CN117964735A (en)	2024-05-03
PE20211417A1 (en)	2021-08-02
MX2020010505A (en)	2021-01-15
AU2023203430B2 (en)	2025-07-03
JOP20200251A1 (en)	2020-10-04
EP3774862B1 (en)	2022-06-08
HUE067499T2 (en)	2024-10-28
US11866477B2 (en)	2024-01-09
US20200362007A1 (en)	2020-11-19
CL2020002574A1 (en)	2021-06-04
AU2025242190A1 (en)	2025-10-23
PT4122954T (en)	2024-06-05
NZ768446A (en)	2025-10-31
MX2024007688A (en)	2024-07-09
US11873328B2 (en)	2024-01-16
JP2021520346A (en)	2021-08-19
DK4122954T3 (en)	2024-06-10
US11447535B2 (en)	2022-09-20
US20190309040A1 (en)	2019-10-10
WO2019193576A1 (en)	2019-10-10

Publication	Publication Date	Title
IL277483A (en)	2020-11-30	Novel glp-1 analogues
CA190078S (en)	2021-04-23	Case
SG11202105586YA (en)	2021-06-29	Modified gip peptide analogues
GB202005105D0 (en)	2020-05-20	n
GB2577682B (en)	2021-10-20	Auto-injector
GB2582783B (en)	2021-05-12	Checkpointing
GB2589548B (en)	2022-09-07	Auto-Injector
PL3630806T3 (en)	2024-05-13	Long-acting gip peptide analogues
GB2575149B (en)	2023-07-05	Lanyards
GB201800400D0 (en)	2018-02-21	Structural components
ZA202100322B (en)	2022-08-31	Polytunnel structure
GB2591977B (en)	2022-03-16	Auto-Injector
GB202002530D0 (en)	2020-04-08	N
CA204449S (en)	2021-11-25	Auto-injector
SMT202300247T1 (en)	2023-11-13	Triazacyclododecansulfonamide (
CA189431S (en)	2020-11-02	Case
CA189432S (en)	2020-11-02	Case
GB202006585D0 (en)	2020-06-17	n
HK40060357A (en)	2022-05-13	Modified gip peptide analogues
GB2576916B (en)	2022-09-07	Polytunnel structure
GB201908550D0 (en)	2019-07-31	n
GB2575634B (en)	2020-12-16	Polytunnel structure
GB201818676D0 (en)	2019-01-02	Polytunnel structure
GB201803158D0 (en)	2018-04-11	Improved structure