PL3770160T3 - Środki kontrastowe na bazie PCTA zawierające gadolin - Google Patents

Środki kontrastowe na bazie PCTA zawierające gadolin

Info

Publication number: PL3770160T3
Authority: PL; Poland
Prior art keywords: pcta; contrast agents; agents containing; based contrast; containing gadolinium
Prior art date: 2018-08-06

Application number

PL20193824.8T

Other languages

English (en)

Inventor

Roberta Napolitano

Luciano Lattuada

Zsolt Baranyai

Nicole GUIDOLIN

Giuseppe Marazzi

Original Assignee

Bracco Imaging Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-08-06

Filing date

2019-08-06

Publication date

2023-05-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=63165233&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3770160(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2019-08-06 Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa

2023-05-29 Publication of PL3770160T3 publication Critical patent/PL3770160T3/pl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
- A61K49/108—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA the metal complex being Gd-DOTA
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Radiology & Medical Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PL20193824.8T 2018-08-06 2019-08-06 Środki kontrastowe na bazie PCTA zawierające gadolin PL3770160T3 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP18187422		2018-08-06

Publications (1)

Publication Number	Publication Date
PL3770160T3 true PL3770160T3 (pl)	2023-05-29

Family

ID=63165233

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
PL19753296T PL3687994T3 (pl)	2018-08-06	2019-08-06	Środki kontrastowe na bazie pcta zawierające gadolin
PL22205189.8T PL4151637T3 (pl)	2018-08-06	2019-08-06	Środki kontrastowe na bazie PCTA zawierające gadolin
PL20193824.8T PL3770160T3 (pl)	2018-08-06	2019-08-06	Środki kontrastowe na bazie PCTA zawierające gadolin

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
PL19753296T PL3687994T3 (pl)	2018-08-06	2019-08-06	Środki kontrastowe na bazie pcta zawierające gadolin
PL22205189.8T PL4151637T3 (pl)	2018-08-06	2019-08-06	Środki kontrastowe na bazie PCTA zawierające gadolin

Country Status (14)

Country	Link
US (3)	US10973934B2 (pl)
EP (4)	EP4491199A3 (pl)
JP (2)	JP7558146B2 (pl)
KR (2)	KR102815156B1 (pl)
CN (4)	CN119930615A (pl)
AU (1)	AU2019319599B2 (pl)
BR (1)	BR112021001102B1 (pl)
CA (1)	CA3105610C (pl)
DK (3)	DK3770160T3 (pl)
ES (3)	ES2841070T3 (pl)
FI (2)	FI4151637T3 (pl)
PL (3)	PL3687994T3 (pl)
PT (3)	PT3687994T (pl)
WO (1)	WO2020030618A1 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP7558146B2 (ja) *	2018-08-06	2024-09-30	ブラッコ・イメージング・ソシエタ・ペル・アチオニ	Ｐｃｔａベースの造影剤
US11370804B2 (en)	2019-01-17	2022-06-28	Guerbet	Complex of gadolinium and a chelating ligand derived from a diastereoisomerically enriched PCTA and preparation and purification process
FR3091872B1 (fr) *	2019-01-17	2020-12-25	Guerbet Sa	Complexe de gadolinium et d’un ligand chelateur derive de pcta diastereoisomeriquement enrichi et procede de synthese
US11426470B2 (en)	2019-01-17	2022-08-30	Guerbet	Complex of gadolinium and a chelating ligand derived of a diastereoisomerically enriched PCTA and synthesis method
FR3091873B1 (fr) *	2019-01-17	2020-12-25	Guerbet Sa	Complexe de gadolinium et d’un ligand chelateur derive de pcta diastereoisomeriquement enrichi et procede de preparation et de purification
LT4025259T (lt) *	2019-09-03	2025-02-10	Ge Healthcare As	Mangano chelato izomerai
FI4143153T3 (fi) *	2020-07-16	2023-12-20	Guerbet Sa	Menetelmä 2-bromiglutaarihapon diesterien synteesiä varten
KR20230041007A (ko) *	2020-07-17	2023-03-23	게르브	Pcta로부터 유도된 킬레이팅 리간드의 제조 방법
WO2024046833A1 (de)	2022-08-30	2024-03-07	Bayer Aktiengesellschaft	Erzeugen von synthetischen radiologischen aufnahmen
WO2024046831A1 (de)	2022-08-30	2024-03-07	Bayer Aktiengesellschaft	Erzeugen von synthetischen radiologischen aufnahmen
EP4581641A1 (de)	2022-08-30	2025-07-09	Bayer Aktiengesellschaft	Erzeugen von synthetischen radiologischen aufnahmen
JP2025529949A (ja) *	2022-09-01	2025-09-09	テラノキュアカンパニーリミテッド	新規化合物、およびこれを含むｍｒｉ造影剤
KR102845061B1 (ko) *	2022-09-01	2025-08-13	주식회사 테라노큐어	신규한 화합물 및 이를 포함하는 mri 조영제
WO2024052156A1 (de)	2022-09-05	2024-03-14	Bayer Aktiengesellschaft	Erzeugen von künstlichen kontrastverstärkten radiologischen aufnahmen
WO2024083466A1 (de)	2022-10-17	2024-04-25	Bayer Aktiengesellschaft	Automatisches analysieren von radiologischen aufnahmen
EP4369353A1 (de)	2022-11-12	2024-05-15	Bayer Aktiengesellschaft	Erzeugung von künstlichen kontrastmittelverstärkten radiologischen aufnahmen
EP4471710B1 (de)	2023-05-30	2025-12-17	Bayer Aktiengesellschaft	Erkennen von artefakten in synthetischen medizinischen aufnahmen
EP4475137B1 (de)	2023-06-05	2025-12-03	Bayer Aktiengesellschaft	Erzeugen von künstlichen kontrastverstärkten radiologischen aufnahmen
WO2024251601A1 (de)	2023-06-05	2024-12-12	Bayer Aktiengesellschaft	Erzeugen von künstlichen kontrastverstärkten radiologischen aufnahmen
EP4498324A1 (de)	2023-07-25	2025-01-29	Bayer AG	Erkennen von artefakten in synthetischen bildern
WO2025045168A1 (zh) *	2023-09-01	2025-03-06	江苏恒瑞医药股份有限公司	一种大环化合物及其用途
EP4567716A1 (en)	2023-12-06	2025-06-11	Bayer Aktiengesellschaft	Generating synthetic representations
EP4567715A1 (en)	2023-12-06	2025-06-11	Bayer Aktiengesellschaft	Generating synthetic representations
WO2025190828A1 (en)	2024-03-15	2025-09-18	Bayer Aktiengesellschaft	Correction of an mri image
EP4664393A1 (de)	2024-06-10	2025-12-17	Bayer Aktiengesellschaft	Erzeugen von synthetischen kontrastverstärkten radiologischen aufnahmen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0992245A1 (en)	1998-09-16	2000-04-12	Goldham Bioglan Pharma GmbH	Radio-contrast agents
FR2794744B1 (fr)	1999-06-09	2001-09-21	Guerbet Sa	Complexes metalliques de polyaminoacides bicycliques, leur procede de preparation et leur application en imagerie medicale
FR2836916B1 (fr)	2002-03-05	2004-06-11	Guerbet Sa	Oligomeres de chelates de gadolinium, leur application comme produits de contraste en imagerie par resonance magnetique et leurs intermediaires de synthese
FR2883562B1 (fr)	2005-03-24	2009-02-27	Guerbet Sa	Chelates lipophiles et leur utilisation en imagerie
FR2891830B1 (fr) *	2005-10-07	2011-06-24	Guerbet Sa	Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale
JP6608805B2 (ja)	2013-04-26	2019-11-20	ゲルベ	造影製剤および関連する調製方法
JP7558146B2 (ja) *	2018-08-06	2024-09-30	ブラッコ・イメージング・ソシエタ・ペル・アチオニ	Ｐｃｔａベースの造影剤
FR3091873B1 (fr)	2019-01-17	2020-12-25	Guerbet Sa	Complexe de gadolinium et d’un ligand chelateur derive de pcta diastereoisomeriquement enrichi et procede de preparation et de purification

2019
- 2019-08-06 JP JP2021506481A patent/JP7558146B2/ja active Active
- 2019-08-06 EP EP24217012.4A patent/EP4491199A3/en active Pending
- 2019-08-06 US US16/766,619 patent/US10973934B2/en active Active
- 2019-08-06 CN CN202510106257.3A patent/CN119930615A/zh active Pending
- 2019-08-06 KR KR1020217003707A patent/KR102815156B1/ko active Active
- 2019-08-06 PT PT197532963T patent/PT3687994T/pt unknown
- 2019-08-06 ES ES19753296T patent/ES2841070T3/es active Active
- 2019-08-06 FI FIEP22205189.8T patent/FI4151637T3/fi active
- 2019-08-06 PL PL19753296T patent/PL3687994T3/pl unknown
- 2019-08-06 DK DK20193824.8T patent/DK3770160T3/da active
- 2019-08-06 ES ES22205189T patent/ES3015456T3/es active Active
- 2019-08-06 PT PT201938248T patent/PT3770160T/pt unknown
- 2019-08-06 KR KR1020257017484A patent/KR20250079243A/ko active Pending
- 2019-08-06 FI FIEP20193824.8T patent/FI3770160T3/fi active
- 2019-08-06 WO PCT/EP2019/071075 patent/WO2020030618A1/en not_active Ceased
- 2019-08-06 PT PT222051898T patent/PT4151637T/pt unknown
- 2019-08-06 EP EP19753296.3A patent/EP3687994B1/en active Active
- 2019-08-06 CN CN202510106265.8A patent/CN119954806A/zh active Pending
- 2019-08-06 EP EP22205189.8A patent/EP4151637B1/en active Active
- 2019-08-06 BR BR112021001102-1A patent/BR112021001102B1/pt active IP Right Grant
- 2019-08-06 PL PL22205189.8T patent/PL4151637T3/pl unknown
- 2019-08-06 CN CN202410642657.1A patent/CN119039292A/zh active Pending
- 2019-08-06 ES ES20193824T patent/ES2938015T3/es active Active
- 2019-08-06 DK DK22205189.8T patent/DK4151637T3/da active
- 2019-08-06 PL PL20193824.8T patent/PL3770160T3/pl unknown
- 2019-08-06 DK DK19753296.3T patent/DK3687994T3/da active
- 2019-08-06 CA CA3105610A patent/CA3105610C/en active Active
- 2019-08-06 EP EP20193824.8A patent/EP3770160B1/en active Active
- 2019-08-06 AU AU2019319599A patent/AU2019319599B2/en active Active
- 2019-08-06 CN CN201980052546.2A patent/CN112533921B/zh active Active
2021
- 2021-03-11 US US17/199,122 patent/US12036289B2/en active Active
2024
- 2024-06-05 US US18/734,341 patent/US20240366802A1/en active Pending
- 2024-09-17 JP JP2024160004A patent/JP2024178261A/ja active Pending

Also Published As

Publication number	Publication date
AU2019319599B2 (en)	2024-01-04
AU2019319599A1 (en)	2021-01-28
EP4151637A1 (en)	2023-03-22
DK3770160T3 (da)	2023-02-20
ES2841070T3 (es)	2021-07-07
CN112533921B (zh)	2025-02-21
KR102815156B1 (ko)	2025-05-30
PL3687994T3 (pl)	2021-05-04
CA3105610A1 (en)	2020-02-13
PL4151637T3 (pl)	2025-04-28
EP4151637B1 (en)	2025-01-22
ES2938015T3 (es)	2023-04-03
US20210196840A1 (en)	2021-07-01
BR112021001102A2 (pt)	2021-04-20
US10973934B2 (en)	2021-04-13
KR20250079243A (ko)	2025-06-04
EP3687994A1 (en)	2020-08-05
BR112021001102B1 (pt)	2022-12-20
EP4491199A2 (en)	2025-01-15
CN119930615A (zh)	2025-05-06
JP7558146B2 (ja)	2024-09-30
ES3015456T3 (en)	2025-05-05
PT4151637T (pt)	2025-03-26
KR20210041566A (ko)	2021-04-15
CA3105610C (en)	2024-05-28
US20200376145A1 (en)	2020-12-03
PT3687994T (pt)	2020-12-07
EP4491199A3 (en)	2025-04-16
EP3770160A1 (en)	2021-01-27
CN112533921A (zh)	2021-03-19
WO2020030618A1 (en)	2020-02-13
EP3770160B1 (en)	2022-11-23
DK3687994T3 (da)	2021-01-25
US12036289B2 (en)	2024-07-16
DK4151637T3 (da)	2025-03-31
FI4151637T3 (fi)	2025-03-28
CN119039292A (zh)	2024-11-29
EP3687994B1 (en)	2020-11-04
US20240366802A1 (en)	2024-11-07
JP2024178261A (ja)	2024-12-24
PT3770160T (pt)	2023-02-21
CN119954806A (zh)	2025-05-09
JP2021533165A (ja)	2021-12-02
FI3770160T3 (fi)	2023-03-16

Publication	Publication Date	Title
PL3770160T3 (pl)	2023-05-29	Środki kontrastowe na bazie PCTA zawierające gadolin
IL286833A (en)	2021-10-31	Compositions containing brazzein
MA47609A (fr)	2020-01-01	Anticorps anti-il31 à usage vétérinaire
LT3810602T (lt)	2024-01-25	Junginiai
PL3910421T3 (pl)	2024-07-22	Kaseta na toner
EP3338142A4 (en)	2019-04-03	INK DEVELOPER
DK3866931T3 (da)	2023-04-24	Forbindelser indeholdende deuterium
EP3803743A4 (en)	2021-07-28	CONSISTENT TOKENIZATION INDEPENDENT OF THE SOURCE
LT3781200T (lt)	2024-08-12	Chelatintų radionuklidų antikūnai
PL3662894T3 (pl)	2022-01-10	Nanocząstki zawierające takrolimus
CL2018002821S1 (es)	2019-03-29	Envase
IL279620B1 (en)	2025-11-01	Compounds
EP3823902C0 (de)	2023-11-08	Behälter
EP3857311C0 (en)	2025-01-15	DEVELOPMENT CARTRIDGE
DK3569989T3 (da)	2023-05-30	Fluidmåler
EP3763628A4 (en)	2021-12-08	CONTAINER
EP3482729A4 (en)	2019-08-14	Pull-up type absorbent article
PL3856106T3 (pl)	2024-12-16	Strój
EP3831399A4 (en)	2021-09-08	AGENT AGAINST NOROVIRUS
EP3658993A4 (en)	2020-12-30	DEVELOPMENT CARTRIDGE
EP4055005A4 (en)	2023-11-29	Liquid melphalan composition
EP3819231C0 (en)	2024-01-10	Application container
EP3704032C0 (de)	2023-11-15	Behälter
DK3659700T3 (da)	2022-06-13	Magnetisk koblet væskeblander
EP3641761A4 (en)	2021-03-24	ALPHA-SYNUCLEIN MODULATORS