PL3755681T3 - Sposób wytwarzania 4-boronofenyloalaniny - Google Patents
Sposób wytwarzania 4-boronofenyloalaninyInfo
- Publication number
- PL3755681T3 PL3755681T3 PL19711724.5T PL19711724T PL3755681T3 PL 3755681 T3 PL3755681 T3 PL 3755681T3 PL 19711724 T PL19711724 T PL 19711724T PL 3755681 T3 PL3755681 T3 PL 3755681T3
- Authority
- PL
- Poland
- Prior art keywords
- boronophenylalanine
- production
- boronophenylalanine production
- Prior art date
Links
- NFIVJOSXJDORSP-QMMMGPOBSA-N (2s)-2-amino-3-(4-boronophenyl)propanoic acid Chemical compound OC(=O)[C@@H](N)CC1=CC=C(B(O)O)C=C1 NFIVJOSXJDORSP-QMMMGPOBSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B47/00—Formation or introduction of functional groups not provided for in groups C07B39/00 - C07B45/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B49/00—Grignard reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B51/00—Introduction of protecting groups or activating groups, not provided for in the preceding groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B63/00—Purification; Separation; Stabilisation; Use of additives
- C07B63/02—Purification; Separation; Stabilisation; Use of additives by treatment giving rise to a chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/02—Magnesium compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862632862P | 2018-02-20 | 2018-02-20 | |
| PCT/JP2019/005984 WO2019163738A1 (en) | 2018-02-20 | 2019-02-19 | Method of 4-boronophenylalanine production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3755681T3 true PL3755681T3 (pl) | 2022-11-28 |
Family
ID=65812368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19711724.5T PL3755681T3 (pl) | 2018-02-20 | 2019-02-19 | Sposób wytwarzania 4-boronofenyloalaniny |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11098067B2 (pl) |
| EP (1) | EP3755681B1 (pl) |
| JP (1) | JP7273854B2 (pl) |
| KR (1) | KR102635698B1 (pl) |
| CN (1) | CN111741939A (pl) |
| EA (1) | EA202091962A1 (pl) |
| ES (1) | ES2929196T3 (pl) |
| PL (1) | PL3755681T3 (pl) |
| WO (1) | WO2019163738A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230416280A1 (en) * | 2020-11-13 | 2023-12-28 | Stella Pharma Corporation | Method for producing 4-borono-l-phenylalanine and intermediate thereof |
| FR3120630B1 (fr) * | 2021-03-09 | 2023-02-10 | Orano Chimie Enrichissement | Composé boré utile pour la séparation isotopique du bore, son procédé de synthèse et ses utilisations |
| CN116925119A (zh) * | 2022-03-30 | 2023-10-24 | 海南普利制药股份有限公司 | 一种4-10硼酸-l-苯丙氨酸中间体的制备方法 |
| CN119039332A (zh) * | 2024-08-26 | 2024-11-29 | 西安交通大学 | 多硼酸取代苯丙氨酸化合物及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9206628A (es) * | 1991-11-22 | 1993-05-01 | Boehringer Ingelheim Pharma | Ester de prolinaboronato y metodo para su preparacion. |
| AU1932295A (en) * | 1994-03-04 | 1995-09-18 | Procter & Gamble Company, The | Process for making monoacetals of hydroquinone |
| JP2000212185A (ja) | 1999-01-14 | 2000-08-02 | Ajinomoto Co Inc | パラボロノフェニルアラニン誘導体の製造方法 |
| CN102875340B (zh) * | 2011-07-12 | 2015-05-20 | 北大方正集团有限公司 | 一种沙格雷酯中间体及其制备方法 |
| EP2865682B1 (en) | 2013-10-28 | 2016-10-26 | Taiwan Biotech Co., Ltd. | Process for preparing 4-Borono-L-Phenylalanine |
| CN104961756A (zh) | 2015-06-16 | 2015-10-07 | 上海应用技术学院 | 一种(S)-Boc-4-二羟基硼酰苯丙氨酸的制备方法 |
| JP6831834B2 (ja) | 2015-08-14 | 2021-02-17 | 南京中硼▲聯▼康医▲療▼科技有限公司Neuboron Medtech Ltd. | L−bpaの調製方法 |
| CN107488188B (zh) * | 2016-06-12 | 2019-03-15 | 重庆圣华曦药业股份有限公司 | 一种制备特地唑胺关键中间体的合成方法 |
-
2019
- 2019-02-19 EA EA202091962A patent/EA202091962A1/ru unknown
- 2019-02-19 CN CN201980014146.2A patent/CN111741939A/zh active Pending
- 2019-02-19 WO PCT/JP2019/005984 patent/WO2019163738A1/en not_active Ceased
- 2019-02-19 EP EP19711724.5A patent/EP3755681B1/en active Active
- 2019-02-19 JP JP2020566096A patent/JP7273854B2/ja active Active
- 2019-02-19 US US16/971,275 patent/US11098067B2/en active Active
- 2019-02-19 KR KR1020207026563A patent/KR102635698B1/ko active Active
- 2019-02-19 PL PL19711724.5T patent/PL3755681T3/pl unknown
- 2019-02-19 ES ES19711724T patent/ES2929196T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3755681A1 (en) | 2020-12-30 |
| KR20200123441A (ko) | 2020-10-29 |
| ES2929196T3 (es) | 2022-11-25 |
| CN111741939A (zh) | 2020-10-02 |
| US20200392163A1 (en) | 2020-12-17 |
| JP2021514008A (ja) | 2021-06-03 |
| KR102635698B1 (ko) | 2024-02-14 |
| EA202091962A1 (ru) | 2020-11-06 |
| US11098067B2 (en) | 2021-08-24 |
| WO2019163738A1 (en) | 2019-08-29 |
| EP3755681B1 (en) | 2022-09-07 |
| JP7273854B2 (ja) | 2023-05-15 |
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